product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Ku-86 (B-1) Antibody
catalog :
sc-5280
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-1
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; fig 5
Li L, Shi L, Yang S, Yan R, Zhang D, Yang J, et al. SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability. Nat Commun. 2016;7:12235 pubmed publisher
  • western blot; human; fig 2b
Mukherjee S, Chakraborty P, Saha P. Phosphorylation of Ku70 subunit by cell cycle kinases modulates the replication related function of Ku heterodimer. Nucleic Acids Res. 2016;44:7755-65 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 4c
Swann J, Murry J, Young J. Cytosolic sulfotransferase 1A1 regulates HIV-1 minus-strand DNA elongation in primary human monocyte-derived macrophages. Virol J. 2016;13:30 pubmed publisher
  • western blot; human; fig 1
Laurette P, Strub T, Koludrovic D, Keime C, Le Gras S, Seberg H, et al. Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells. elife. 2015;4: pubmed publisher
  • western blot; human; fig 6a
Wu Z, Wang C, Bai M, Li X, Mei Q, Li X, et al. An LRP16-containing preassembly complex contributes to NF-κB activation induced by DNA double-strand breaks. Nucleic Acids Res. 2015;43:3167-79 pubmed publisher
  • western blot; human; 1:500; fig 2, 3
Raghunandan M, Chaudhury I, Kelich S, Hanenberg H, Sobeck A. FANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex. Cell Cycle. 2015;14:342-53 pubmed publisher
  • western blot; human
Dutta B, Yan R, Lim S, Tam J, Sze S. Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesis. Mol Cell Proteomics. 2014;13:3236-49 pubmed publisher
  • western blot; human
Zhou Y, Caron P, Legube G, Paull T. Quantitation of DNA double-strand break resection intermediates in human cells. Nucleic Acids Res. 2014;42:e19 pubmed publisher
Munnur D, Somers J, Skalka G, Weston R, Jukes Jones R, Bhogadia M, et al. NR4A Nuclear Receptors Target Poly-ADP-Ribosylated DNA-PKcs Protein to Promote DNA Repair. Cell Rep. 2019;26:2028-2036.e6 pubmed publisher
Liu H, Wang X, Feng B, Tang L, Li W, Zheng X, et al. Golgi phosphoprotein 3 (GOLPH3) promotes hepatocellular carcinoma progression by activating mTOR signaling pathway. BMC Cancer. 2018;18:661 pubmed publisher
Thompson E, Yeo J, Lee E, Kan Y, Raghunandan M, Wiek C, et al. FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response. Nucleic Acids Res. 2017;45:11837-11857 pubmed publisher
Avgousti D, Herrmann C, Kulej K, Pancholi N, Sekulic N, Petrescu J, et al. A core viral protein binds host nucleosomes to sequester immune danger signals. Nature. 2016;535:173-7 pubmed
Kalra R, Bapat S. Enhanced levels of double-strand DNA break repair proteins protect ovarian cancer cells against genotoxic stress-induced apoptosis. J Ovarian Res. 2013;6:66 pubmed publisher
Berti M, Ray Chaudhuri A, Thangavel S, Gomathinayagam S, Kenig S, Vujanovic M, et al. Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition. Nat Struct Mol Biol. 2013;20:347-54 pubmed publisher
Song L, Robson T, Doig T, Brenn T, Mathers M, Brown E, et al. DNA repair and replication proteins as prognostic markers in melanoma. Histopathology. 2013;62:343-50 pubmed publisher
Adeyemi R, Landry S, Davis M, Weitzman M, Pintel D. Parvovirus minute virus of mice induces a DNA damage response that facilitates viral replication. PLoS Pathog. 2010;6:e1001141 pubmed publisher
Wang Y, Ghosh G, Hendrickson E. Ku86 represses lethal telomere deletion events in human somatic cells. Proc Natl Acad Sci U S A. 2009;106:12430-5 pubmed publisher
Wu X, Geraldes P, Platt J, Cascalho M. The double-edged sword of activation-induced cytidine deaminase. J Immunol. 2005;174:934-41 pubmed
product information
Product Name :
Ku-86 (B-1) Antibody
Gene Name :
XRCC5
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-5280
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Ku-86
reactive species  :
human
Application :
WB, IP, IF, IHC(P), FCM, ELISA
Epitope :
433-732 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA