product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
CD63 (MX-49.129.5) Antibody
catalog :
sc-5275
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MX-49.129.5
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 41
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:200; loading ...; fig 2a, s3a
Yokoi A, Villar Prados A, Oliphint P, Zhang J, Song X, De Hoff P, et al. Mechanisms of nuclear content loading to exosomes. Sci Adv. 2019;5:eaax8849 pubmed publisher
  • western blot; mouse; loading ...; fig s1c
Zhang Y, Jin X, Liang J, Guo Y, Sun G, Zeng X, et al. Extracellular vesicles derived from ODN-stimulated macrophages transfer and activate Cdc42 in recipient cells and thereby increase cellular permissiveness to EV uptake. Sci Adv. 2019;5:eaav1564 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1b
  • western blot; mouse; 1:1000; loading ...; fig 4b
Zhang H, Deng T, Ge S, Liu Y, Bai M, Zhu K, et al. Exosome circRNA secreted from adipocytes promotes the growth of hepatocellular carcinoma by targeting deubiquitination-related USP7. Oncogene. 2019;38:2844-2859 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s3c
Shi G, OZOG S, Torbett B, Compton A. mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3. Proc Natl Acad Sci U S A. 2018;115:E10069-E10078 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s1a
Kühnl A, Musiol A, Heitzig N, Johnson D, Ehrhardt C, Grewal T, et al. Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus. MBio. 2018;9: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3c
Chia J, Louber J, Glauser I, Taylor S, Bass G, Dower S, et al. Half-life-extended recombinant coagulation factor IX-albumin fusion protein is recycled via the FcRn-mediated pathway. J Biol Chem. 2018;293:6363-6373 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s1b
Toh W, Chia P, Hossain M, Gleeson P. GGA1 regulates signal-dependent sorting of BACE1 to recycling endosomes, which moderates Aβ production. Mol Biol Cell. 2018;29:191-208 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4e
Guo H, Chitiprolu M, Roncevic L, Javalet C, Hemming F, Trung M, et al. Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy. Dev Cell. 2017;43:716-730.e7 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 7
Wang G, Zhou H, Strulovici Barel Y, Al Hijji M, Ou X, Salit J, et al. Role of OSGIN1 in mediating smoking-induced autophagy in the human airway epithelium. Autophagy. 2017;13:1205-1220 pubmed publisher
  • western blot; human; 1 ug/ml; loading ...; fig 2b
Lang J, Young R, Ashraf H, Canty J. Inhibiting Extracellular Vesicle Release from Human Cardiosphere Derived Cells with Lentiviral Knockdown of nSMase2 Differentially Effects Proliferation and Apoptosis in Cardiomyocytes, Fibroblasts and Endothelial Cells In Vitro. PLoS ONE. 2016;11:e0165926 pubmed publisher
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 3
Labani Motlagh A, Israelsson P, Ottander U, Lundin E, Nagaev I, Nagaeva O, et al. Differential expression of ligands for NKG2D and DNAM-1 receptors by epithelial ovarian cancer-derived exosomes and its influence on NK cell cytotoxicity. Tumour Biol. 2016;37:5455-66 pubmed publisher
  • immunocytochemistry; human; fig 3
Cavaletto N, Luganini A, Gribaudo G. Inactivation of the Human Cytomegalovirus US20 Gene Hampers Productive Viral Replication in Endothelial Cells. J Virol. 2015;89:11092-106 pubmed publisher
  • immunocytochemistry; human; fig s1b
Munson M, Allen G, Toth R, Campbell D, Lucocq J, Ganley I. mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival. EMBO J. 2015;34:2272-90 pubmed publisher
  • western blot; human; 1 ug/ml; fig 2
Shao H, Chung J, Lee K, Balaj L, Min C, Carter B, et al. Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma. Nat Commun. 2015;6:6999 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400
Ivan V, van der Sluijs P. Methods for analysis of AP-3/Rabin4' in regulation of lysosome distribution. Methods Mol Biol. 2015;1298:245-58 pubmed publisher
  • western blot; human; 1:400; fig 7
Honegger A, Schilling D, Bastian S, Sponagel J, Kuryshev V, Sultmann H, et al. Dependence of intracellular and exosomal microRNAs on viral E6/E7 oncogene expression in HPV-positive tumor cells. PLoS Pathog. 2015;11:e1004712 pubmed publisher
  • immunocytochemistry; human
Ribeiro Rodrigues T, Catarino S, Marques C, Ferreira J, Martins Marques T, Pereira P, et al. AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions. FASEB J. 2014;28:4629-41 pubmed publisher
  • western blot; human; loading ...; fig s1a
Ye S, Li Z, Luo D, Huang B, Chen Y, Zhang X, et al. Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma. Oncotarget. 2014;5:5439-52 pubmed
  • flow cytometry; human; fig 6E
Bund T, Spoden G, Koynov K, Hellmann N, Boukhallouk F, Arnold P, et al. An L2 SUMO interacting motif is important for PML localization and infection of human papillomavirus type 16. Cell Microbiol. 2014;16:1179-200 pubmed publisher
  • western blot; human
Kashiwagi E, Izumi H, Yasuniwa Y, Baba R, Doi Y, Kidani A, et al. Enhanced expression of nuclear factor I/B in oxaliplatin-resistant human cancer cell lines. Cancer Sci. 2011;102:382-6 pubmed publisher
Luo Y, Huang L, Luo W, Ye S, Hu Q. Genomic analysis of lncRNA and mRNA profiles in circulating exosomes of patients with rheumatic heart disease. Biol Open. 2019;8: pubmed publisher
Hannafon B, Gin A, Xu Y, Bruns M, Calloway C, Ding W. Metastasis-associated protein 1 (MTA1) is transferred by exosomes and contributes to the regulation of hypoxia and estrogen signaling in breast cancer cells. Cell Commun Signal. 2019;17:13 pubmed publisher
Klymiuk M, Balz N, Elashry M, Heimann M, Wenisch S, Arnhold S. Exosomes isolation and identification from equine mesenchymal stem cells. BMC Vet Res. 2019;15:42 pubmed publisher
Doyle T, Moncorgé O, Bonaventure B, Pollpeter D, Lussignol M, Tauziet M, et al. The interferon-inducible isoform of NCOA7 inhibits endosome-mediated viral entry. Nat Microbiol. 2018;3:1369-1376 pubmed publisher
Hikita T, Miyata M, Watanabe R, Oneyama C. Sensitive and rapid quantification of exosomes by fusing luciferase to exosome marker proteins. Sci Rep. 2018;8:14035 pubmed publisher
Aaberg Jessen C, Sørensen M, Matos A, Moreira J, Brunner N, Knudsen A, et al. Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas. BMC Cancer. 2018;18:270 pubmed publisher
Gao T, Liu X, He B, Nie Z, Zhu C, Zhang P, et al. Exosomal lncRNA 91H is associated with poor development in colorectal cancer by modifying HNRNPK expression. Cancer Cell Int. 2018;18:11 pubmed publisher
Gosavi P, Houghton F, McMillan P, Hanssen E, Gleeson P. The Golgi ribbon in mammalian cells negatively regulates autophagy by modulating mTOR activity. J Cell Sci. 2018;131: pubmed publisher
de Godoy M, Saraiva L, de Carvalho L, Vasconcelos dos Santos A, Beiral H, Ramos A, et al. Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers. J Biol Chem. 2018;293:1957-1975 pubmed publisher
Luganini A, Cavaletto N, Raimondo S, Geuna S, Gribaudo G. Loss of the Human Cytomegalovirus US16 Protein Abrogates Virus Entry into Endothelial and Epithelial Cells by Reducing the Virion Content of the Pentamer. J Virol. 2017;91: pubmed publisher
Ando T, Kudo Y, Iizuka S, Tsunematsu T, Umehara H, Shrestha M, et al. Ameloblastin induces tumor suppressive phenotype and enhances chemosensitivity to doxorubicin via Src-Stat3 inactivation in osteosarcoma. Sci Rep. 2017;7:40187 pubmed publisher
Banning A, Gülec C, Rouvinen J, Gray S, Tikkanen R. Identification of Small Molecule Compounds for Pharmacological Chaperone Therapy of Aspartylglucosaminuria. Sci Rep. 2016;6:37583 pubmed publisher
Hannafon B, Trigoso Y, Calloway C, Zhao Y, Lum D, Welm A, et al. Plasma exosome microRNAs are indicative of breast cancer. Breast Cancer Res. 2016;18:90 pubmed publisher
Fiskaa T, Knutsen E, Nikolaisen M, Jørgensen T, Johansen S, Perander M, et al. Distinct Small RNA Signatures in Extracellular Vesicles Derived from Breast Cancer Cell Lines. PLoS ONE. 2016;11:e0161824 pubmed publisher
Jung J, Robinson C. IL-12 and IL-27 regulate the phagolysosomal pathway in mycobacteria-infected human macrophages. Cell Commun Signal. 2014;12:16 pubmed publisher
Honegger A, Leitz J, Bulkescher J, Hoppe Seyler K, Hoppe Seyler F. Silencing of human papillomavirus (HPV) E6/E7 oncogene expression affects both the contents and the amounts of extracellular microvesicles released from HPV-positive cancer cells. Int J Cancer. 2013;133:1631-42 pubmed publisher
Aytekin M, Aulak K, Haserodt S, Chakravarti R, Cody J, Minai O, et al. Abnormal platelet aggregation in idiopathic pulmonary arterial hypertension: role of nitric oxide. Am J Physiol Lung Cell Mol Physiol. 2012;302:L512-20 pubmed publisher
Bommarito A, Richiusa P, Carissimi E, Pizzolanti G, Rodolico V, Zito G, et al. BRAFV600E mutation, TIMP-1 upregulation, and NF-κB activation: closing the loop on the papillary thyroid cancer trilogy. Endocr Relat Cancer. 2011;18:669-85 pubmed publisher
Luo S, Ishibashi O, Ishikawa G, Ishikawa T, Katayama A, Mishima T, et al. Human villous trophoblasts express and secrete placenta-specific microRNAs into maternal circulation via exosomes. Biol Reprod. 2009;81:717-29 pubmed publisher
Spoden G, Freitag K, Husmann M, Boller K, Sapp M, Lambert C, et al. Clathrin- and caveolin-independent entry of human papillomavirus type 16--involvement of tetraspanin-enriched microdomains (TEMs). PLoS ONE. 2008;3:e3313 pubmed publisher
Strasner A, Natarajan M, Doman T, Key D, August A, Henderson A. The Src kinase Lck facilitates assembly of HIV-1 at the plasma membrane. J Immunol. 2008;181:3706-13 pubmed
product information
Product Name :
CD63 (MX-49.129.5) Antibody
Gene Name :
CD63
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-5275
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
CD63
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), FCM, ELISA
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA