product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
c-Src (H-12) Antibody
catalog :
sc-5266
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H-12
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 3
da Silva P, Do Amaral V, Gabrielli V, Montt Guevara M, Mannella P, Baracat E, et al. Prolactin Promotes Breast Cancer Cell Migration through Actin Cytoskeleton Remodeling. Front Endocrinol (Lausanne). 2015;6:186 pubmed publisher
  • western blot; mouse; fig s4
De Mario A, Castellani A, Peggion C, Massimino M, Lim D, Hill A, et al. The prion protein constitutively controls neuronal store-operated Ca(2+) entry through Fyn kinase. Front Cell Neurosci. 2015;9:416 pubmed publisher
  • western blot; human; fig 4
Chen P, Wu T, Cheng Y, Chen C, Lee H. NKX2-1-mediated p53 expression modulates lung adenocarcinoma progression via modulating IKKβ/NF-κB activation. Oncotarget. 2015;6:14274-89 pubmed
  • western blot; human
Flamini M, Gauna G, Sottile M, Nadin B, Sanchez A, Vargas Roig L. Retinoic acid reduces migration of human breast cancer cells: role of retinoic acid receptor beta. J Cell Mol Med. 2014;18:1113-23 pubmed publisher
  • western blot; human; 1:500
Groenendyk J, Michalak M. Disrupted WNT signaling in mouse embryonic stem cells in the absence of calreticulin. Stem Cell Rev. 2014;10:191-206 pubmed publisher
  • western blot; human; fig s2
Luo J, Xu T, Li C, Ba X, Wang X, Jiang Y, et al. p85-RhoGDI2, a novel complex, is required for PSGL-1-induced ?1 integrin-mediated lymphocyte adhesion to VCAM-1. Int J Biochem Cell Biol. 2013;45:2764-73 pubmed publisher
Shanzer M, Adler J, Ricardo Lax I, Reuven N, Shaul Y. The nonreceptor tyrosine kinase c-Src attenuates SCF(β-TrCP) E3-ligase activity abrogating Taz proteasomal degradation. Proc Natl Acad Sci U S A. 2017;114:1678-1683 pubmed publisher
Szalmás A, Gyöngyösi E, Ferenczi A, László B, Karosi T, Csomor P, et al. Activation of Src, Fyn and Yes non-receptor tyrosine kinases in keratinocytes expressing human papillomavirus (HPV) type 16 E7 oncoprotein. Virol J. 2013;10:79 pubmed publisher
Theocharis S, Klijanienko J, Giaginis C, Alexandrou P, Patsouris E, Sastre Garau X. FAK and Src expression in mobile tongue squamous cell carcinoma: associations with clinicopathological parameters and patients survival. J Cancer Res Clin Oncol. 2012;138:1369-77 pubmed publisher
Linley A, Mathieu M, Miles A, Rees R, McArdle S, Regad T. The helicase HAGE expressed by malignant melanoma-initiating cells is required for tumor cell proliferation in vivo. J Biol Chem. 2012;287:13633-43 pubmed publisher
Sanchez A, Flamini M, Zullino S, Gopal S, Genazzani A, Simoncini T. Estrogen receptor-{alpha} promotes endothelial cell motility through focal adhesion kinase. Mol Hum Reprod. 2011;17:219-26 pubmed publisher
Chatzizacharias N, Giaginis C, Gatzidou E, Tsourouflis G, Sfiniadakis I, Alexandrou P, et al. Expression and clinical significance of FAK and Src proteins in human endometrial adenocarcinoma. Pathol Oncol Res. 2011;17:277-85 pubmed publisher
Sanchez A, Flamini M, Baldacci C, Goglia L, Genazzani A, Simoncini T. Estrogen receptor-alpha promotes breast cancer cell motility and invasion via focal adhesion kinase and N-WASP. Mol Endocrinol. 2010;24:2114-25 pubmed publisher
Flamini M, Sanchez A, Genazzani A, Simoncini T. Estrogen regulates endometrial cell cytoskeletal remodeling and motility via focal adhesion kinase. Fertil Steril. 2011;95:722-6 pubmed publisher
Michailidi C, Giaginis C, Stolakis V, Alexandrou P, Klijanienko J, Delladetsima I, et al. Evaluation of FAK and Src expression in human benign and malignant thyroid lesions. Pathol Oncol Res. 2010;16:497-507 pubmed publisher
Sinha S, Vohra P, Bhattacharya R, Dutta S, Sinha S, Mukhopadhyay D. Dopamine regulates phosphorylation of VEGF receptor 2 by engaging Src-homology-2-domain-containing protein tyrosine phosphatase 2. J Cell Sci. 2009;122:3385-92 pubmed publisher
Bhattacharya R, Sinha S, Yang S, Patra C, Dutta S, Wang E, et al. The neurotransmitter dopamine modulates vascular permeability in the endothelium. J Mol Signal. 2008;3:14 pubmed publisher
Perrone L, Peluso G, Melone M. RAGE recycles at the plasma membrane in S100B secretory vesicles and promotes Schwann cells morphological changes. J Cell Physiol. 2008;217:60-71 pubmed publisher
Bernard Trifilo J, Lim S, Hou S, Schlaepfer D, Ilic D. Analyzing FAK and Pyk2 in early integrin signaling events. Curr Protoc Cell Biol. 2006;Chapter 14:Unit 14.7 pubmed publisher
Hu X, Dang Y, Tenney K, Crews P, Tsai C, Sixt K, et al. Regulation of c-Src nonreceptor tyrosine kinase activity by bengamide A through inhibition of methionine aminopeptidases. Chem Biol. 2007;14:764-74 pubmed
Anderson M, Harrison R, Atherfold P, Campbell M, Darnton S, Obszynska J, et al. Met receptor signaling: a key effector in esophageal adenocarcinoma. Clin Cancer Res. 2006;12:5936-43 pubmed
Miyamoto Y, Chen L, Sato M, Sokabe M, Nabeshima T, Pawson T, et al. Hippocampal synaptic modulation by the phosphotyrosine adapter protein ShcC/N-Shc via interaction with the NMDA receptor. J Neurosci. 2005;25:1826-35 pubmed
product information
Product Name :
c-Src (H-12) Antibody
Gene Name :
SRC
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-5266
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
c-Src
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
N-terminal (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA