| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry; pigs ; loading ...; fig 3b
| He S, Li L, Chen H, Hu X, Wang W, Zhang H, et al. PRRSV Infection Induces Gasdermin D-Driven Pyroptosis of Porcine Alveolar Macrophages through NLRP3 Inflammasome Activation. J Virol. 2022;96:e0212721 pubmed publisher |
- western blot; mouse; 1:200; loading ...; fig 2a
| Su Y, Wang Y, Liu M, Chen H. Hydrogen sulfide attenuates renal I/R‑induced activation of the inflammatory response and apoptosis via regulating Nrf2‑mediated NLRP3 signaling pathway inhibition. Mol Med Rep. 2021;24: pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 5a
- western blot; mouse; 1:1000; loading ...; fig 5b
| Ni X, Zhang Y, Jia L, Lu W, Zhu Q, Ren J, et al. Inhibition of Notch1-mediated inflammation by intermedin protects against abdominal aortic aneurysm via PI3K/Akt signaling pathway. Aging (Albany NY). 2021;13:5164-5184 pubmed publisher |
- western blot; mouse; loading ...; fig 3e
| Kim Y, Kim J, Gu S, Jo S, Kim S, Young Kim S, et al. Identification of highly potent and selective inhibitor, TIPTP, of the p22phox-Rubicon axis as a therapeutic agent for rheumatoid arthritis. Sci Rep. 2020;10:4570 pubmed publisher |
- western blot; mouse; loading ...; fig 5b
| Theivanthiran B, Evans K, Devito N, Plebanek M, Sturdivant M, Wachsmuth L, et al. A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy. J Clin Invest. 2020;130:2570-2586 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 2b
| Yuan B, Zhou X, You Z, Xu W, Fan J, Chen S, et al. Inhibition of AIM2 inflammasome activation alleviates GSDMD-induced pyroptosis in early brain injury after subarachnoid haemorrhage. Cell Death Dis. 2020;11:76 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3a
| Yang Y, Liu P, Bao W, Chen S, Wu F, Zhu P. Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway. BMC Cancer. 2020;20:28 pubmed publisher |
- western blot; human; loading ...; fig 2c, 5a
| Gordon E, Yao X, Xu H, Karkowsky W, Kaler M, Kalchiem Dekel O, et al. Apolipoprotein E is a concentration-dependent pulmonary danger signal that activates the NLRP3 inflammasome and IL-1β secretion by bronchoalveolar fluid macrophages from asthmatic subjects. J Allergy Clin Immunol. 2019;: pubmed publisher |
- western blot; mouse; loading ...; fig 6c
| Arora H, Wilcox S, Johnson L, Munro L, Eyford B, Pfeifer C, et al. The ATP-Binding Cassette Gene ABCF1 Functions as an E2 Ubiquitin-Conjugating Enzyme Controlling Macrophage Polarization to Dampen Lethal Septic Shock. Immunity. 2019;50:418-431.e6 pubmed publisher |
- western blot; human; 1:100; loading ...; fig 3
| Ma Z, Sun H, Lv J, Guo L, Yang Q. Expression and clinical significance of the NEK7-NLRP3 inflammasome signaling pathway in patients with systemic lupus erythematosus. J Inflamm (Lond). 2018;15:16 pubmed publisher |
- immunoprecipitation; rat; fig 3c
- western blot; rat; fig 3c
| Lin Z, Wang S, Chen L, Zhuang J, Ke Q, Xiao D, et al. Methylene Blue Mitigates Acute Neuroinflammation after Spinal Cord Injury through Inhibiting NLRP3 Inflammasome Activation in Microglia. Front Cell Neurosci. 2017;11:391 pubmed publisher |
| McLemore A, Hou H, Meyer B, Lam N, Ward G, Aldrich A, et al. Somatic gene mutations expose cytoplasmic DNA to co-opt the cGAS-STING-NLRP3 axis in Myelodysplastic syndromes. JCI Insight. 2022;: pubmed publisher |
| Bombaci G, Sarangdhar M, Andina N, Tardivel A, Yu E, Mackie G, et al. LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity. Life Sci Alliance. 2022;5: pubmed publisher |
| Zou C, Beard J, Yang G, Evans W, Bonten E. CASPorter: A Novel Inducible Human CASP1/NALP3/ASC Inflammasome Biosensor. J Inflamm Res. 2022;15:1183-1194 pubmed publisher |
| Cordaro M, Fusco R, D Amico R, Siracusa R, Peritore A, Gugliandolo E, et al. Cashew (Anacardium occidentale L.) Nuts Modulate the Nrf2 and NLRP3 Pathways in Pancreas and Lung after Induction of Acute Pancreatitis by Cerulein. Antioxidants (Basel). 2020;9: pubmed publisher |
| Deng Z, Ni J, Wu X, Wei H, Peng J. GPA peptide inhibits NLRP3 inflammasome activation to ameliorate colitis through AMPK pathway. Aging (Albany NY). 2020;12:18522-18544 pubmed publisher |
| Zhai Y, Meng X, Ye T, Xie W, Sun G, Sun X. Inhibiting the NLRP3 Inflammasome Activation with MCC950 Ameliorates Diabetic Encephalopathy in db/db Mice. Molecules. 2018;23: pubmed publisher |
