Garc a Arroyo F, Monroy S nchez F, Mu oz Jim nez I, Gonzaga G, Andr s Hernando A, Zazueta C, et al. Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed Rats. Biomolecules. 2019;9: pubmed publisher

Shan L, Liu W, Zhan Y. Sulfated polysaccharide of Sepiella maindroni ink targets Akt and overcomes resistance to the FGFR inhibitor AZD4547 in bladder cancer. Aging (Albany NY). 2019;11:7780-7795 pubmed publisher

Chollat Namy M, Ben Safta Saadoun T, Haferssas D, Meurice G, Chouaib S, Thiery J. The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy. Cell Death Dis. 2019;10:695 pubmed publisher

Greenhough A, Bagley C, Heesom K, Gurevich D, Gay D, Bond M, et al. Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis. EMBO Mol Med. 2018;10: pubmed publisher

Pearce M, Gamble J, Kopparapu P, O Donnell E, Mueller M, Jang H, et al. Induction of apoptosis and suppression of tumor growth by Nur77-derived Bcl-2 converting peptide in chemoresistant lung cancer cells. Oncotarget. 2018;9:26072-26085 pubmed publisher

Zhao X, Huang L, Xu W, Chen X, Shen Y, Zeng W, et al. Physapubescin B inhibits tumorgenesis and circumvents taxol resistance of ovarian cancer cells through STAT3 signaling. Oncotarget. 2017;8:70130-70141 pubmed publisher

Liu Y, Chen X, Li J. Resveratrol protects against oxidized low‑density lipoprotein‑induced human umbilical vein endothelial cell apoptosis via inhibition of mitochondrial‑derived oxidative stress. Mol Med Rep. 2017;15:2457-2464 pubmed publisher

Jinesh G, Molina J, Huang L, Laing N, Mills G, Bar Eli M, et al. Mitochondrial oligomers boost glycolysis in cancer stem cells to facilitate blebbishield-mediated transformation after apoptosis. Cell Death Discov. 2016;2:16003 pubmed publisher

Weyhenmeyer B, Noonan J, Würstle M, Lincoln F, Johnston G, Rehm M, et al. Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide. Oncotarget. 2016;7:61295-61311 pubmed publisher

Yu X, Sun K, Tang X, Zhou C, Sun H, Yan Z, et al. Harmine combined with paclitaxel inhibits tumor proliferation and induces apoptosis through down-regulation of cyclooxygenase-2 expression in gastric cancer. Oncol Lett. 2016;12:983-988 pubmed

Peng H, Cheng Y, Hsu Y, Wu G, Kuo C, Liou J, et al. MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma. PLoS ONE. 2016;11:e0158440 pubmed publisher

Tagscherer K, Fassl A, Sinkovic T, Richter J, Schecher S, Macher Goeppinger S, et al. MicroRNA-210 induces apoptosis in colorectal cancer via induction of reactive oxygen. Cancer Cell Int. 2016;16:42 pubmed publisher

Amara S, Zheng M, Tiriveedhi V. Oleanolic Acid Inhibits High Salt-Induced Exaggeration of Warburg-like Metabolism in Breast Cancer Cells. Cell Biochem Biophys. 2016;74:427-34 pubmed publisher

Pires A, Marques C, Encarnação J, Abrantes A, Mamede A, Laranjo M, et al. Ascorbic acid and colon cancer: an oxidative stimulus to cell death depending on cell profile. Eur J Cell Biol. 2016;95:208-18 pubmed publisher

O Neill K, Huang K, Zhang J, Chen Y, Luo X. Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane. Genes Dev. 2016;30:973-88 pubmed publisher

Takeuchi H, Taoka R, Mmeje C, Jinesh G, Safe S, Kamat A. CDODA-Me decreases specificity protein transcription factors and induces apoptosis in bladder cancer cells through induction of reactive oxygen species. Urol Oncol. 2016;34:337.e11-8 pubmed publisher

Huang J, Yao C, Chuang S, Yeh C, Lee L, Chen R, et al. Honokiol inhibits sphere formation and xenograft growth of oral cancer side population cells accompanied with JAK/STAT signaling pathway suppression and apoptosis induction. BMC Cancer. 2016;16:245 pubmed publisher

Brito A, Ribeiro M, Abrantes A, Mamede A, Laranjo M, Casalta Lopes J, et al. New Approach for Treatment of Primary Liver Tumors: The Role of Quercetin. Nutr Cancer. 2016;68:250-66 pubmed publisher

Gilormini M, Malesys C, Armandy E, Manas P, Guy J, Magne N, et al. Preferential targeting of cancer stem cells in the radiosensitizing effect of ABT-737 on HNSCC. Oncotarget. 2016;7:16731-44 pubmed publisher

Klumpp D, Misovic M, Szteyn K, Shumilina E, Rudner J, Huber S. Targeting TRPM2 Channels Impairs Radiation-Induced Cell Cycle Arrest and Fosters Cell Death of T Cell Leukemia Cells in a Bcl-2-Dependent Manner. Oxid Med Cell Longev. 2016;2016:8026702 pubmed publisher

De Luca T, Pelosi A, Trisciuoglio D, D Aguanno S, Desideri M, Farini V, et al. miR-211 and MITF modulation by Bcl-2 protein in melanoma cells. Mol Carcinog. 2016;55:2304-2312 pubmed publisher

Zucal C, D Agostino V, Casini A, Mantelli B, Thongon N, Soncini D, et al. EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition. BMC Cancer. 2015;15:855 pubmed publisher

Amigo Jiménez I, Bailón E, Aguilera Montilla N, Terol M, García Marco J, García Pardo A. Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways. Oncotarget. 2015;6:44832-48 pubmed publisher

Herriott A, Tudhope S, Junge G, Rodrigues N, Patterson M, Woodhouse L, et al. PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia. Oncotarget. 2015;6:43978-91 pubmed publisher

Salim H, Zong D, Hååg P, Novak M, Mörk B, Lewensohn R, et al. DKK1 is a potential novel mediator of cisplatin-refractoriness in non-small cell lung cancer cell lines. BMC Cancer. 2015;15:628 pubmed publisher

Schmidt L, Kümmel A, Görlich D, Mohr M, Bröckling S, Mikesch J, et al. PD-1 and PD-L1 Expression in NSCLC Indicate a Favorable Prognosis in Defined Subgroups. PLoS ONE. 2015;10:e0136023 pubmed publisher

Kumarasamy V, Shin Y, White J, Sun D. Selective repression of RET proto-oncogene in medullary thyroid carcinoma by a natural alkaloid berberine. BMC Cancer. 2015;15:599 pubmed publisher

Wu C, Huang K, Yang T, Li Y, Wen C, Hsu S, et al. The Topoisomerase 1 Inhibitor Austrobailignan-1 Isolated from Koelreuteria henryi Induces a G2/M-Phase Arrest and Cell Death Independently of p53 in Non-Small Cell Lung Cancer Cells. PLoS ONE. 2015;10:e0132052 pubmed publisher

Masotti A, Donninelli G, Da Sacco L, Varano B, Del Cornò M, Gessani S. HIV-1 gp120 influences the expression of microRNAs in human monocyte-derived dendritic cells via STAT3 activation. BMC Genomics. 2015;16:480 pubmed publisher

Mavroeidis L, Sheldon H, Briasoulis E, Marselos M, Pappas P, Harris A. Metronomic vinorelbine: Anti-angiogenic activity in vitro in normoxic and severe hypoxic conditions, and severe hypoxia-induced resistance to its anti-proliferative effect with reversal by Akt inhibition. Int J Oncol. 2015;47:455-64 pubmed publisher

Giunta S, Castorina A, Marzagalli R, Szychlinska M, Pichler K, Mobasheri A, et al. Ameliorative effects of PACAP against cartilage degeneration. Morphological, immunohistochemical and biochemical evidence from in vivo and in vitro models of rat osteoarthritis. Int J Mol Sci. 2015;16:5922-44 pubmed publisher

Long J, Schoonen P, Graczyk D, O Prey J, Ryan K. p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death. Oncogene. 2015;34:5152-62 pubmed publisher

Suo H, Song J, Zhou Y, Liu Z, Yi R, Zhu K, et al. Induction of apoptosis in HCT-116 colon cancer cells by polysaccharide of Larimichthys crocea swim bladder. Oncol Lett. 2015;9:972-978 pubmed

Papanikolaou V, Stefanou N, Dubos S, Papathanasiou I, Palianopoulou M, Valiakou V, et al. Synergy of leptin/STAT3 with HER2 receptor induces tamoxifen resistance in breast cancer cells through regulation of apoptosis-related genes. Cell Oncol (Dordr). 2015;38:155-64 pubmed publisher

Zebboudj A, Maroui M, Dutrieux J, Touil Boukoffa C, Bourouba M, Chelbi Alix M, et al. Sodium arsenite induces apoptosis and Epstein-Barr virus reactivation in lymphoblastoid cells. Biochimie. 2014;107 Pt B:247-56 pubmed publisher

Liu Y, Wan S, Zhang P, Zhang W, Zheng J, Lin J, et al. Expression levels of autophagy related proteins and their prognostic significance in retinocytoma and retinoblastoma. Int J Ophthalmol. 2014;7:594-601 pubmed publisher

Morita A, Ariyasu S, Wang B, Asanuma T, Onoda T, Sawa A, et al. AS-2, a novel inhibitor of p53-dependent apoptosis, prevents apoptotic mitochondrial dysfunction in a transcription-independent manner and protects mice from a lethal dose of ionizing radiation. Biochem Biophys Res Commun. 2014;450:1498-504 pubmed publisher

Bai L, Chen J, McEachern D, Liu L, Zhou H, Aguilar A, et al. BM-1197: a novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivo. PLoS ONE. 2014;9:e99404 pubmed publisher

Ding K, Banerjee A, Tan S, Zhao J, Zhuang Q, Li R, et al. Artemin, a member of the glial cell line-derived neurotrophic factor family of ligands, is HER2-regulated and mediates acquired trastuzumab resistance by promoting cancer stem cell-like behavior in mammary carcinoma cells. J Biol Chem. 2014;289:16057-71 pubmed publisher

Xargay Torrent S, Lopez Guerra M, Saborit Villarroya I, Rosich L, Campo E, Roué G, et al. Vorinostat-induced apoptosis in mantle cell lymphoma is mediated by acetylation of proapoptotic BH3-only gene promoters. Clin Cancer Res. 2011;17:3956-68 pubmed publisher

Liu J, Zhou W, Li S, Sun Z, Lin B, Lang Y, et al. Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues. Cancer Res. 2008;68:8871-80 pubmed publisher

Rieger J, Lemke D, Maurer G, Weiler M, Frank B, Tabatabai G, et al. Enzastaurin-induced apoptosis in glioma cells is caspase-dependent and inhibited by BCL-XL. J Neurochem. 2008;106:2436-48 pubmed publisher

Martin Latil S, Mousson L, Autret A, Colbere Garapin F, Blondel B. Bax is activated during rotavirus-induced apoptosis through the mitochondrial pathway. J Virol. 2007;81:4457-64 pubmed

Seiler K, Humbert M, Minder P, Mashimo I, Schläfli A, Krauer D, et al. Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions. Cell Death Dis. 2022;13:448 pubmed publisher

Chrysostomou S, Roy R, Prischi F, Thamlikitkul L, Chapman K, Mufti U, et al. Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer. Sci Transl Med. 2021;13: pubmed publisher

Huang K, O Neill K, Li J, Zhou W, Han N, Pang X, et al. BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis. Cell Res. 2019;29:942-952 pubmed publisher

Chand H, Harris J, Tesfaigzi Y. IL-13 in LPS-Induced Inflammation Causes Bcl-2 Expression to Sustain Hyperplastic Mucous cells. Sci Rep. 2018;8:436 pubmed publisher

Zhao H, Li Q, Pang J, Jin H, Li H, Yang X. Blocking autophagy enhances the pro-apoptotic effect of bufalin on human gastric cancer cells through endoplasmic reticulum stress. Biol Open. 2017;6:1416-1422 pubmed publisher

Moindjie H, Santos E, Gouesse R, Swierkowski Blanchard N, Serazin V, Barnea E, et al. Preimplantation factor is an anti-apoptotic effector in human trophoblasts involving p53 signaling pathway. Cell Death Dis. 2016;7:e2504 pubmed publisher

Dunnill C, Ibraheem K, Mohamed A, Southgate J, Georgopoulos N. A redox state-dictated signalling pathway deciphers the malignant cell specificity of CD40-mediated apoptosis. Oncogene. 2017;36:2515-2528 pubmed publisher

Luo Z, Zhu W, Guo Q, Luo W, Zhang J, Xu W, et al. Weaning Induced Hepatic Oxidative Stress, Apoptosis, and Aminotransferases through MAPK Signaling Pathways in Piglets. Oxid Med Cell Longev. 2016;2016:4768541 pubmed

Fedoseienko A, Wieringa H, Wisman G, Duiker E, Reyners A, Hofker M, et al. Nuclear COMMD1 Is Associated with Cisplatin Sensitivity in Ovarian Cancer. PLoS ONE. 2016;11:e0165385 pubmed publisher

Phatak N, Stankowska D, Krishnamoorthy R. Bcl-2, Bcl-xL, and p-AKT are involved in neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucoma. Mol Vis. 2016;22:1048-61 pubmed

Ni H, Zhang L, Ren S, Sun B. Long-term expression of zinc transporters in hippocampus following penicillin-induced developmental seizures and its regulation by E-64d. Exp Ther Med. 2016;12:208-214 pubmed

Geng F, Cheng X, Wu X, Yoo J, Cheng C, Guo J, et al. Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis. Clin Cancer Res. 2016;22:5337-5348 pubmed

Feng N, Hao G, Yang F, Qu F, Zheng H, Liang S, et al. Transplantation of mesenchymal stem cells promotes the functional recovery of the central nervous system following cerebral ischemia by inhibiting myelin-associated inhibitor expression and neural apoptosis. Exp Ther Med. 2016;11:1595-1600 pubmed

Qian J, Bai H, Gao Z, Dong Y, Pei J, Ma M, et al. Downregulation of HIF-1? inhibits the proliferation and invasion of non-small cell lung cancer NCI-H157 cells. Oncol Lett. 2016;11:1738-1744 pubmed

Teng J, Wu S, Chen J, Li Q, Peng F, Zhu Z, et al. The Activation of ERK1/2 and JNK MAPK Signaling by Insulin/IGF-1 Is Responsible for the Development of Colon Cancer with Type 2 Diabetes Mellitus. PLoS ONE. 2016;11:e0149822 pubmed publisher

Chernova T, Sun X, Powley I, Galavotti S, Grosso S, Murphy F, et al. Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease. Cell Death Differ. 2016;23:1152-64 pubmed publisher

Jiang C, Fang X, Jiang Y, Shen F, Hu Z, Li X, et al. TNF-α induces vascular endothelial cells apoptosis through overexpressing pregnancy induced noncoding RNA in Kawasaki disease model. Int J Biochem Cell Biol. 2016;72:118-124 pubmed publisher

Acikgoz E, Guven U, Duzagac F, Uslu R, Kara M, Soner B, et al. Enhanced G2/M Arrest, Caspase Related Apoptosis and Reduced E-Cadherin Dependent Intercellular Adhesion by Trabectedin in Prostate Cancer Stem Cells. PLoS ONE. 2015;10:e0141090 pubmed publisher

Guo H, Cui H, Peng X, Fang J, Zuo Z, Deng J, et al. Modulation of the PI3K/Akt Pathway and Bcl-2 Family Proteins Involved in Chicken's Tubular Apoptosis Induced by Nickel Chloride (NiCl₂). Int J Mol Sci. 2015;16:22989-3011 pubmed publisher

Lavik A, Zhong F, Chang M, Greenberg E, Choudhary Y, Smith M, et al. A synthetic peptide targeting the BH4 domain of Bcl-2 induces apoptosis in multiple myeloma and follicular lymphoma cells alone or in combination with agents targeting the BH3-binding pocket of Bcl-2. Oncotarget. 2015;6:27388-402 pubmed publisher

Liu K, Frazier W. Phosphorylation of the BNIP3 C-Terminus Inhibits Mitochondrial Damage and Cell Death without Blocking Autophagy. PLoS ONE. 2015;10:e0129667 pubmed publisher

Liu F, Liu C, Li X, Zheng S, Li Q, Liu Q, et al. Neuroprotective effects of SMADs in a rat model of cerebral ischemia/reperfusion. Neural Regen Res. 2015;10:438-44 pubmed publisher

Wong M, Nicholson C, Holloway A, Hardy D. Maternal nicotine exposure leads to impaired disulfide bond formation and augmented endoplasmic reticulum stress in the rat placenta. PLoS ONE. 2015;10:e0122295 pubmed publisher

Shinohara H, Taniguchi K, Kumazaki M, Yamada N, Ito Y, Otsuki Y, et al. Anti-cancer fatty-acid derivative induces autophagic cell death through modulation of PKM isoform expression profile mediated by bcr-abl in chronic myeloid leukemia. Cancer Lett. 2015;360:28-38 pubmed publisher

Eichhorn J, Kothari A, Chambers T. Cyclin B1 overexpression induces cell death independent of mitotic arrest. PLoS ONE. 2014;9:e113283 pubmed publisher

Fu X, Creighton C, Biswal N, Kumar V, Shea M, Herrera S, et al. Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase. Breast Cancer Res. 2014;16:430 pubmed publisher

Wolfe A, Singh K, Zhong Y, Drewe P, Rajasekhar V, Sanghvi V, et al. RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer. Nature. 2014;513:65-70 pubmed publisher

Stengel C, Newman S, Day J, Chander S, Jourdan F, Leese M, et al. In vivo and in vitro properties of STX2484: a novel non-steroidal anti-cancer compound active in taxane-resistant breast cancer. Br J Cancer. 2014;111:300-8 pubmed publisher

Amigo Jiménez I, Bailón E, Ugarte Berzal E, Aguilera Montilla N, García Marco J, García Pardo A. Matrix metalloproteinase-9 is involved in chronic lymphocytic leukemia cell response to fludarabine and arsenic trioxide. PLoS ONE. 2014;9:e99993 pubmed publisher

Mega C, Vala H, Rodrigues Santos P, Oliveira J, Teixeira F, Fernandes R, et al. Sitagliptin prevents aggravation of endocrine and exocrine pancreatic damage in the Zucker Diabetic Fatty rat - focus on amelioration of metabolic profile and tissue cytoprotective properties. Diabetol Metab Syndr. 2014;6:42 pubmed publisher

Li X, Suo J, Shao S, Xue L, Chen W, Dong L, et al. Overexpression of OLC1 promotes tumorigenesis of human esophageal squamous cell carcinoma. PLoS ONE. 2014;9:e90958 pubmed publisher

Guo S, Li Z, Jiang D, Lu Y, Liu Y, Gao L, et al. IRF4 is a novel mediator for neuronal survival in ischaemic stroke. Cell Death Differ. 2014;21:888-903 pubmed publisher

Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, et al. GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis. Cell Death Dis. 2014;5:e1028 pubmed publisher

Yurube T, Hirata H, Kakutani K, Maeno K, Takada T, Zhang Z, et al. Notochordal cell disappearance and modes of apoptotic cell death in a rat tail static compression-induced disc degeneration model. Arthritis Res Ther. 2014;16:R31 pubmed publisher

Morita A, Ariyasu S, Ohya S, Takahashi I, Wang B, Tanaka K, et al. Evaluation of zinc (II) chelators for inhibiting p53-mediated apoptosis. Oncotarget. 2013;4:2439-50 pubmed

Eichhorn J, Alford S, Hughes C, Fenical W, Chambers T. Purported Mcl-1 inhibitor marinopyrrole A fails to show selective cytotoxicity for Mcl-1-dependent cell lines. Cell Death Dis. 2013;4:e880 pubmed publisher

Eichhorn J, Sakurikar N, Alford S, Chu R, Chambers T. Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death. Cell Death Dis. 2013;4:e834 pubmed publisher

Whilding L, Archibald K, Kulbe H, Balkwill F, Oberg D, McNeish I. Vaccinia virus induces programmed necrosis in ovarian cancer cells. Mol Ther. 2013;21:2074-86 pubmed publisher

Cawley K, Logue S, Gorman A, Zeng Q, Patterson J, Gupta S, et al. Disruption of microRNA biogenesis confers resistance to ER stress-induced cell death upstream of the mitochondrion. PLoS ONE. 2013;8:e73870 pubmed publisher

Passante E, Würstle M, Hellwig C, Leverkus M, Rehm M. Systems analysis of apoptosis protein expression allows the case-specific prediction of cell death responsiveness of melanoma cells. Cell Death Differ. 2013;20:1521-31 pubmed publisher

Baltadzhiev I, Delchev S. Changes of Bcl-2, Bax and Caspase-3 expression in the dermal microvascular endothelial cells and the epidermal layers of the eschar (tache noire) in patients with Mediterranean spotted fever. Folia Histochem Cytobiol. 2013;51:121-6 pubmed publisher

Galbiatti A, Castro R, Caldas H, Padovani J, Pavarino E, Goloni Bertollo E. Alterations in the expression pattern of MTHFR, DHFR, TYMS, and SLC19A1 genes after treatment of laryngeal cancer cells with high and low doses of methotrexate. Tumour Biol. 2013;34:3765-71 pubmed publisher

Wang Y, Li C, Pan L, Gao Z. 7,8-Dihydroxycoumarin inhibits A549 human lung adenocarcinoma cell proliferation by inducing apoptosis via suppression of Akt/NF-?B signaling. Exp Ther Med. 2013;5:1770-1774 pubmed

Yan K, Lee L, Hsieh M, Yan M, Yao C, Chang P, et al. Aspirin antagonizes the cytotoxic effect of methotrexate in lung cancer cells. Oncol Rep. 2013;30:1497-505 pubmed publisher

Borgdorff V, Rix U, Winter G, Gridling M, Müller A, Breitwieser F, et al. A chemical biology approach identifies AMPK as a modulator of melanoma oncogene MITF. Oncogene. 2014;33:2531-9 pubmed publisher

Eißmann M, Schwamb B, Melzer I, Moser J, Siele D, Köhl U, et al. A functional yeast survival screen of tumor-derived cDNA libraries designed to identify anti-apoptotic mammalian oncogenes. PLoS ONE. 2013;8:e64873 pubmed publisher

Gantke T, Boussouf S, Janzen J, Morrice N, Howell S, Mühlberger E, et al. Ebola virus VP35 induces high-level production of recombinant TPL-2-ABIN-2-NF-?B1 p105 complex in co-transfected HEK-293 cells. Biochem J. 2013;452:359-65 pubmed publisher

Gai L, Cai N, Wang L, Xu X, Kong X. Ursolic acid induces apoptosis via Akt/NF-?B signaling suppression in T24 human bladder cancer cells. Mol Med Rep. 2013;7:1673-7 pubmed publisher

Boiani M, Daniel C, Liu X, Hogarty M, Marnett L. The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737. J Biol Chem. 2013;288:6980-90 pubmed publisher

Basile V, Belluti S, Ferrari E, Gozzoli C, Ganassi S, Quaglino D, et al. bis-Dehydroxy-Curcumin triggers mitochondrial-associated cell death in human colon cancer cells through ER-stress induced autophagy. PLoS ONE. 2013;8:e53664 pubmed publisher

Zhou M, Zheng L, Guo L, Liu W, Lv C, Jiang L, et al. Differential responses to UVB irradiation in human keratinocytes and epidermoid carcinoma cells. Biomed Environ Sci. 2012;25:583-9 pubmed publisher

Teng Y, Manavalan T, Hu C, Medjakovic S, Jungbauer A, Klinge C. Endocrine disruptors fludioxonil and fenhexamid stimulate miR-21 expression in breast cancer cells. Toxicol Sci. 2013;131:71-83 pubmed publisher

Legartova S, Jugova A, Stixova L, Kozubek S, Fojtova M, Zdrahal Z, et al. Epigenetic aspects of HP1 exchange kinetics in apoptotic chromatin. Biochimie. 2013;95:167-79 pubmed publisher

Hung T, Chen S, Lo L, Li M, Yeh Y, Hsieh T. Increased autophagy in placentas of intrauterine growth-restricted pregnancies. PLoS ONE. 2012;7:e40957 pubmed publisher

Ikezoe T, Yang J, Nishioka C, Honda G, Furihata M, Yokoyama A. Thrombomodulin protects endothelial cells from a calcineurin inhibitor-induced cytotoxicity by upregulation of extracellular signal-regulated kinase/myeloid leukemia cell-1 signaling. Arterioscler Thromb Vasc Biol. 2012;32:2259-70 pubmed publisher

Rodust P, Fecker L, Stockfleth E, Eberle J. Activation of mitochondrial apoptosis pathways in cutaneous squamous cell carcinoma cells by diclofenac/hyaluronic acid is related to upregulation of Bad as well as downregulation of Mcl-1 and Bcl-w. Exp Dermatol. 2012;21:520-5 pubmed publisher

Serra A, Rocha Gonsalves A, Laranjo M, Abrantes A, Gonçalves A, Sarmento Ribeiro A, et al. Synthesis of new 2-galactosylthiazolidine-4-carboxylic acid amides. Antitumor evaluation against melanoma and breast cancer cells. Eur J Med Chem. 2012;53:398-402 pubmed publisher

al Yacoub N, Fecker L, Möbs M, Plötz M, Braun F, Sterry W, et al. Apoptosis induction by SAHA in cutaneous T-cell lymphoma cells is related to downregulation of c-FLIP and enhanced TRAIL signaling. J Invest Dermatol. 2012;132:2263-74 pubmed publisher

Leake K, Singhal J, Nagaprashantha L, Awasthi S, Singhal S. RLIP76 regulates PI3K/Akt signaling and chemo-radiotherapy resistance in pancreatic cancer. PLoS ONE. 2012;7:e34582 pubmed publisher

Wan X, Zhao Y, Fan X, Cai H, Zhang Y, Chen M, et al. Molecular prognostic prediction for locally advanced nasopharyngeal carcinoma by support vector machine integrated approach. PLoS ONE. 2012;7:e31989 pubmed publisher

Giunta S, Castorina A, Scuderi S, Patti C, D Agata V. Epidermal growth factor receptor (EGFR) and neuregulin (Neu) activation in human airway epithelial cells exposed to nickel acetate. Toxicol In Vitro. 2012;26:280-7 pubmed publisher

Koryllou A, Patrinou Georgoula M, Dimozi A, Kyrtopoulos S, Pletsa V. Investigation of cell death induced by N-methyl-N-nitrosourea in cell lines of human origin and implication of RNA binding protein alterations. Anticancer Res. 2011;31:4291-9 pubmed

Presicce P, Orsborn K, King E, Pratt J, Fichtenbaum C, Chougnet C. Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy. PLoS ONE. 2011;6:e28118 pubmed publisher

Aldridge B, Gaudet S, Lauffenburger D, Sorger P. Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis. Mol Syst Biol. 2011;7:553 pubmed publisher

Chen K, Chang W, Cheung C, Lin C, Huang C, Yang Y, et al. Targeting cathepsin S induces tumor cell autophagy via the EGFR-ERK signaling pathway. Cancer Lett. 2012;317:89-98 pubmed publisher

Jung C, Jo J, Lee S, Park Y, Jung N, Song D, et al. Anti-cancer properties of glucosamine-hydrochloride in YD-8 human oral cancer cells: Induction of the caspase-dependent apoptosis and down-regulation of HIF-1?. Toxicol In Vitro. 2012;26:42-50 pubmed publisher

Braun F, al Yacoub N, Plötz M, Möbs M, Sterry W, Eberle J. Nonsteroidal anti-inflammatory drugs induce apoptosis in cutaneous T-cell lymphoma cells and enhance their sensitivity for TNF-related apoptosis-inducing ligand. J Invest Dermatol. 2012;132:429-39 pubmed publisher

Leskov K, Araki S, Lavik J, Gomez J, Gama V, Gonos E, et al. CRM1 protein-mediated regulation of nuclear clusterin (nCLU), an ionizing radiation-stimulated, Bax-dependent pro-death factor. J Biol Chem. 2011;286:40083-90 pubmed publisher

Kuo K, Chen Y, Chen L, Li C, Lan Y, Chang F, et al. Involvement of phorbol-12-myristate-13-acetate-induced protein 1 in goniothalamin-induced TP53-dependent and -independent apoptosis in hepatocellular carcinoma-derived cells. Toxicol Appl Pharmacol. 2011;256:8-23 pubmed publisher

Polier G, Ding J, Konkimalla B, Eick D, Ribeiro N, Kohler R, et al. Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1. Cell Death Dis. 2011;2:e182 pubmed publisher

Xie Z, Bi C, Cheong L, Liu S, Huang G, Zhou J, et al. Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells. PLoS ONE. 2011;6:e21583 pubmed publisher

Ruckert F, Aust D, Böhme I, Werner K, Brandt A, Diamandis E, et al. Five primary human pancreatic adenocarcinoma cell lines established by the outgrowth method. J Surg Res. 2012;172:29-39 pubmed publisher

Yu Y, Yuan F, Li X, Lin D, Lan Z, Rao C, et al. Luteinizing hormone receptor deficiency increases the susceptibility to alkylating agent-induced lymphomagenesis in mice. Horm Cancer. 2010;1:256-64 pubmed publisher

Morales A, Kurtoglu M, Matulis S, Liu J, Siefker D, Gutman D, et al. Distribution of Bim determines Mcl-1 dependence or codependence with Bcl-xL/Bcl-2 in Mcl-1-expressing myeloma cells. Blood. 2011;118:1329-39 pubmed publisher

Jalili A, Moser A, Pashenkov M, Wagner C, Pathria G, Borgdorff V, et al. Polo-like kinase 1 is a potential therapeutic target in human melanoma. J Invest Dermatol. 2011;131:1886-95 pubmed publisher

Nishioka C, Ikezoe T, Yang J, Udaka K, Yokoyama A. Simultaneous inhibition of DNA methyltransferase and histone deacetylase induces p53-independent apoptosis via down-regulation of Mcl-1 in acute myelogenous leukemia cells. Leuk Res. 2011;35:932-9 pubmed publisher

Laulier C, Barascu A, Guirouilh Barbat J, Pennarun G, Le Chalony C, Chevalier F, et al. Bcl-2 inhibits nuclear homologous recombination by localizing BRCA1 to the endomembranes. Cancer Res. 2011;71:3590-602 pubmed publisher

Goyeneche A, Seidel E, Telleria C. Growth inhibition induced by antiprogestins RU-38486, ORG-31710, and CDB-2914 in ovarian cancer cells involves inhibition of cyclin dependent kinase 2. Invest New Drugs. 2012;30:967-80 pubmed publisher

Kastl L, Brown I, Schofield A. miRNA-34a is associated with docetaxel resistance in human breast cancer cells. Breast Cancer Res Treat. 2012;131:445-54 pubmed publisher

Jeong J, Jin C, Park C, Hong S, Kim G, Jeong Y, et al. Induction of apoptosis by cordycepin via reactive oxygen species generation in human leukemia cells. Toxicol In Vitro. 2011;25:817-24 pubmed publisher

Appelqvist H, Nilsson C, Garner B, Brown A, Kågedal K, Ollinger K. Attenuation of the lysosomal death pathway by lysosomal cholesterol accumulation. Am J Pathol. 2011;178:629-39 pubmed publisher

Brekman A, Singh K, Polotskaia A, Kundu N, Bargonetti J. A p53-independent role of Mdm2 in estrogen-mediated activation of breast cancer cell proliferation. Breast Cancer Res. 2011;13:R3 pubmed publisher

Rufini A, Fortuni S, Arcuri G, Condo I, Serio D, Incani O, et al. Preventing the ubiquitin-proteasome-dependent degradation of frataxin, the protein defective in Friedreich's ataxia. Hum Mol Genet. 2011;20:1253-61 pubmed publisher

Ikezoe T, Kojima S, Furihata M, Yang J, Nishioka C, Takeuchi A, et al. Expression of p-JAK2 predicts clinical outcome and is a potential molecular target of acute myelogenous leukemia. Int J Cancer. 2011;129:2512-21 pubmed publisher

Mantzaris M, Tsianos E, Galaris D. Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells. FEBS J. 2011;278:519-30 pubmed publisher

Yang J, Ikezoe T, Nishioka C, Furihata M, Yokoyama A. AZ960, a novel Jak2 inhibitor, induces growth arrest and apoptosis in adult T-cell leukemia cells. Mol Cancer Ther. 2010;9:3386-95 pubmed publisher

Ikezoe T, Yang J, Nishioka C, Kojima S, Takeuchi A, Phillip Koeffler H, et al. Inhibition of signal transducer and activator of transcription 5 by the inhibitor of janus kinases stimulates dormant human leukemia CD34+ /CD38- cells and sensitizes them to antileukemia agents. Int J Cancer. 2011;128:2317-25 pubmed publisher

Zhang L, Lopez H, George N, Liu X, Pang X, Luo X. Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways. Cell Death Differ. 2011;18:864-73 pubmed publisher

de Boer J, Yeung J, Ellu J, Ramanujachar R, Bornhauser B, Solarska O, et al. The E2A-HLF oncogenic fusion protein acts through Lmo2 and Bcl-2 to immortalize hematopoietic progenitors. Leukemia. 2011;25:321-30 pubmed publisher

Xie Z, Chng W, Tay K, Liu S, Zhou J, Chen C. Therapeutic potential of antisense oligodeoxynucleotides in downregulating p53 oncogenic mutations in cancers. Biotechnol Lett. 2011;33:221-8 pubmed publisher

Hung T, Chen S, Li M, Yeh Y, Hsieh T. Differential effects of concomitant use of vitamins C and E on trophoblast apoptosis and autophagy between normoxia and hypoxia-reoxygenation. PLoS ONE. 2010;5:e12202 pubmed publisher

Garcia Rodriguez L, Abate Daga D, Rojas A, Gonzalez J, Fillat C. E-cadherin contributes to the bystander effect of TK/GCV suicide therapy and enhances its antitumoral activity in pancreatic cancer models. Gene Ther. 2011;18:73-81 pubmed publisher

Ruckert F, Samm N, Lehner A, Saeger H, Grutzmann R, Pilarsky C. Simultaneous gene silencing of Bcl-2, XIAP and Survivin re-sensitizes pancreatic cancer cells towards apoptosis. BMC Cancer. 2010;10:379 pubmed publisher

Alexandru O, Dragutescu L, Tataranu L, Ciubotaru V, Sevastre A, Georgescu A, et al. Helianthin induces antiproliferative effect on human glioblastoma cells in vitro. J Neurooncol. 2011;102:9-18 pubmed publisher

Mowery Y, Weinberg J, Kennedy M, Bond K, Moore J, Lanasa M, et al. LMP-420: a novel purine nucleoside analog with potent cytotoxic effects for CLL cells and minimal toxicity for normal hematopoietic cells. Leukemia. 2010;24:1580-7 pubmed publisher

Andersen S, Rosada C, Dagnaes Hansen F, Laugesen I, de Darkó E, Dam T, et al. Topical application of valrubicin has a beneficial effect on developing skin tumors. Carcinogenesis. 2010;31:1483-90 pubmed publisher

Hruba E, Trilecová L, Marvanová S, Krcmar P, Vykopalová L, Milcova A, et al. Genotoxic polycyclic aromatic hydrocarbons fail to induce the p53-dependent DNA damage response, apoptosis or cell-cycle arrest in human prostate carcinoma LNCaP cells. Toxicol Lett. 2010;197:227-35 pubmed publisher

Gao P, Bauvy C, Souquere S, Tonelli G, Liu L, Zhu Y, et al. The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells. J Biol Chem. 2010;285:25570-81 pubmed publisher

Wood K, Voss O, Huang Q, Parihar A, Mehta N, Batra S, et al. The small heat shock protein 27 is a key regulator of CD8+ CD57+ lymphocyte survival. J Immunol. 2010;184:5582-8 pubmed publisher

Greenhough A, Wallam C, Hicks D, Moorghen M, Williams A, Paraskeva C. The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE(2) signalling in colorectal adenoma cells. Oncogene. 2010;29:3398-410 pubmed publisher

Lopez H, Zhang L, George N, Liu X, Pang X, Evans J, et al. Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damage. J Biol Chem. 2010;285:15016-26 pubmed publisher

Yosifov D, Todorov P, Zaharieva M, Georgiev K, Pilicheva B, Konstantinov S, et al. Erucylphospho-N,N,N-trimethylpropylammonium (erufosine) is a potential antimyeloma drug devoid of myelotoxicity. Cancer Chemother Pharmacol. 2011;67:13-25 pubmed publisher

Li C, Cheng Y, Liao P, Kang J. Translocation of p53 to mitochondria is regulated by its lipid binding property to anionic phospholipids and it participates in cell death control. Neoplasia. 2010;12:150-60 pubmed

Prasad C, Rath G, Mathur S, Bhatnagar D, Ralhan R. Expression analysis of maspin in invasive ductal carcinoma of breast and modulation of its expression by curcumin in breast cancer cell lines. Chem Biol Interact. 2010;183:455-61 pubmed publisher

Mikes J, Kovaľ J, Jendželovský R, Sacková V, Uhrinová I, Kello M, et al. The role of p53 in the efficiency of photodynamic therapy with hypericin and subsequent long-term survival of colon cancer cells. Photochem Photobiol Sci. 2009;8:1558-67 pubmed publisher

Li L, Zuo Z. Isoflurane preconditioning improves short-term and long-term neurological outcome after focal brain ischemia in adult rats. Neuroscience. 2009;164:497-506 pubmed publisher

Schwartz L, Guais A, Pooya M, Abolhassani M. Is inflammation a consequence of extracellular hyperosmolarity?. J Inflamm (Lond). 2009;6:21 pubmed publisher

Danielsson O, Nilsson C, Lindvall B, Ernerudh J. Expression of apoptosis related proteins in normal and diseased muscle: a possible role for Bcl-2 in protection of striated muscle. Neuromuscul Disord. 2009;19:412-7 pubmed publisher

Batsi C, Markopoulou S, Kontargiris E, Charalambous C, Thomas C, Christoforidis S, et al. Bcl-2 blocks 2-methoxyestradiol induced leukemia cell apoptosis by a p27(Kip1)-dependent G1/S cell cycle arrest in conjunction with NF-kappaB activation. Biochem Pharmacol. 2009;78:33-44 pubmed publisher

Stixova L, Prochazkova J, Soucek K, Hofmanova J, Kozubik A. 5-Lipoxygenase inhibitors potentiate 1alpha,25-dihydroxyvitamin D3-induced monocytic differentiation by activating p38 MAPK pathway. Mol Cell Biochem. 2009;330:229-38 pubmed publisher

Sawai C, Takano T, Takeuchi Y. Experimental neuronal migration disorders following the administration of ibotenate in hamsters: the role of the subventricular zone in the development of cortical dysplasia. J Child Neurol. 2009;24:275-86 pubmed publisher

He D, Fang B. Small hairpin RNA targeting at Bcl-2 increases cytarabine-induced apoptosis in Raji cells. Acta Biochim Biophys Sin (Shanghai). 2009;41:131-6 pubmed

Sasaki R, Narisawa Saito M, Yugawa T, Fujita M, Tashiro H, Katabuchi H, et al. Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes. Carcinogenesis. 2009;30:423-31 pubmed publisher

Zaytseva Y, Wang X, Southard R, Wallis N, Kilgore M. Down-regulation of PPARgamma1 suppresses cell growth and induces apoptosis in MCF-7 breast cancer cells. Mol Cancer. 2008;7:90 pubmed publisher

Konig H, Copland M, Chu S, Jove R, Holyoake T, Bhatia R. Effects of dasatinib on SRC kinase activity and downstream intracellular signaling in primitive chronic myelogenous leukemia hematopoietic cells. Cancer Res. 2008;68:9624-33 pubmed publisher

Upreti M, Galitovskaya E, Chu R, Tackett A, Terrano D, Granell S, et al. Identification of the major phosphorylation site in Bcl-xL induced by microtubule inhibitors and analysis of its functional significance. J Biol Chem. 2008;283:35517-25 pubmed publisher

Xu W, Li X, Chen S, Huang J, Lin S, Lin J, et al. Expression and distribution of S-100, CD83 and apoptosis-related proteins (Fas, FasL and Bcl-2) in tissues of thyroid carcinoma. Eur J Histochem. 2008;52:153-62 pubmed

Sun J, Li Z, Hu Z, Lin X, Zhou N, Xian L, et al. ApoG2 inhibits antiapoptotic Bcl-2 family proteins and induces mitochondria-dependent apoptosis in human lymphoma U937 cells. Anticancer Drugs. 2008;19:967-74 pubmed publisher

Maduro J, de Vries E, Meersma G, Hougardy B, van der Zee A, de Jong S. Targeting pro-apoptotic trail receptors sensitizes HeLa cervical cancer cells to irradiation-induced apoptosis. Int J Radiat Oncol Biol Phys. 2008;72:543-52 pubmed publisher

Ahmed K, Fan M, Nantajit D, Cao N, Li J. Cyclin D1 in low-dose radiation-induced adaptive resistance. Oncogene. 2008;27:6738-48 pubmed publisher

Upreti M, Chu R, Galitovskaya E, Smart S, Chambers T. Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine. Mol Cancer Ther. 2008;7:2224-32 pubmed publisher

Lee H, Lee H, Lee E, Ko S, Bae H, Kim C, et al. Mitochondria-cytochrome C-caspase-9 cascade mediates isorhamnetin-induced apoptosis. Cancer Lett. 2008;270:342-53 pubmed publisher

Winkler J, Saadat K, Díaz Gavilán M, Urban E, Noe C. Oligonucleotide-polyamine conjugates: influence of length and position of 2'-attached polyamines on duplex stability and antisense effect. Eur J Med Chem. 2009;44:670-7 pubmed publisher

Hoepken H, Gispert S, Azizov M, Klinkenberg M, Ricciardi F, Kurz A, et al. Parkinson patient fibroblasts show increased alpha-synuclein expression. Exp Neurol. 2008;212:307-13 pubmed publisher

Stephanova E, Topouzova Hristova T, Konakchieva R. Mitochondria are involved in stress response of A549 alveolar cells to halothane toxicity. Toxicol In Vitro. 2008;22:688-94 pubmed publisher

Ushmorov A, Hogarty M, Liu X, Knauss H, Debatin K, Beltinger C. N-myc augments death and attenuates protective effects of Bcl-2 in trophically stressed neuroblastoma cells. Oncogene. 2008;27:3424-34 pubmed publisher

Tian Z, Si J, Chang Q, Zhou L, Chen S, Xiao P, et al. Antitumor activity and mechanisms of action of total glycosides from aerial part of Cimicifuga dahurica targeted against hepatoma. BMC Cancer. 2007;7:237 pubmed publisher

Xu W, Chen S, Huang J, Zheng Z, Chen L, Lin J, et al. Expression and distribution of S-100 protein, CD83 and apoptosis-related proteins (Fas, FasL and Bcl-2) in thyroid tissues of autoimmune thyroid diseases. Eur J Histochem. 2007;51:291-300 pubmed

Baird S, Aerts J, Eddaoudi A, Lockley M, Lemoine N, McNeish I. Oncolytic adenoviral mutants induce a novel mode of programmed cell death in ovarian cancer. Oncogene. 2008;27:3081-90 pubmed

Yee K, Vousden K. Contribution of membrane localization to the apoptotic activity of PUMA. Apoptosis. 2008;13:87-95 pubmed

Tian Z, Pan R, Chang Q, Si J, Xiao P, Wu E. Cimicifuga foetida extract inhibits proliferation of hepatocellular cells via induction of cell cycle arrest and apoptosis. J Ethnopharmacol. 2007;114:227-33 pubmed

Cheng Z, Chen Y. [Effect of acupuncture combined with intraperitoneal injection of paclitaxel on apoptosis in Lewis mice with lung carcinoma]. Zhen Ci Yan Jiu. 2007;32:153-7 pubmed

Mikes J, Kleban J, Sacková V, Horváth V, Jamborová E, Vaculova A, et al. Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin. Photochem Photobiol Sci. 2007;6:758-66 pubmed

Bartolome F, de Las Cuevas N, Muñoz U, Bermejo F, Martin Requero A. Impaired apoptosis in lymphoblasts from Alzheimer's disease patients: cross-talk of Ca2+/calmodulin and ERK1/2 signaling pathways. Cell Mol Life Sci. 2007;64:1437-48 pubmed

Braun F, Fecker L, Schwarz C, Walden P, Assaf C, Dürkop H, et al. Blockade of death receptor-mediated pathways early in the signaling cascade coincides with distinct apoptosis resistance in cutaneous T-cell lymphoma cells. J Invest Dermatol. 2007;127:2425-37 pubmed

Katsanou E, Halabalaki M, Aligiannis N, Mitakou S, Skaltsounis A, Alexi X, et al. Cytotoxic effects of 2-arylbenzofuran phytoestrogens on human cancer cells: modulation by adrenal and gonadal steroids. J Steroid Biochem Mol Biol. 2007;104:228-36 pubmed

Garofalo M, Romano G, Quintavalle C, Romano M, Chiurazzi F, Zanca C, et al. Selective inhibition of PED protein expression sensitizes B-cell chronic lymphocytic leukaemia cells to TRAIL-induced apoptosis. Int J Cancer. 2007;120:1215-22 pubmed

Kurbanov B, Fecker L, Geilen C, Sterry W, Eberle J. Resistance of melanoma cells to TRAIL does not result from upregulation of antiapoptotic proteins by NF-kappaB but is related to downregulation of initiator caspases and DR4. Oncogene. 2007;26:3364-77 pubmed

Nimmanapalli R, Lyu M, Du M, Keating M, Rosenblum M, Gandhi V. The growth factor fusion construct containing B-lymphocyte stimulator (BLyS) and the toxin rGel induces apoptosis specifically in BAFF-R-positive CLL cells. Blood. 2007;109:2557-64 pubmed

Criollo A, Galluzzi L, Maiuri M, Tasdemir E, Lavandero S, Kroemer G. Mitochondrial control of cell death induced by hyperosmotic stress. Apoptosis. 2007;12:3-18 pubmed

Kok S, Hong C, Lin S, Lee J, Chiang C, Kuo M. Establishment and characterization of a tumorigenic cell line from areca quid and tobacco smoke-associated buccal carcinoma. Oral Oncol. 2007;43:639-47 pubmed

Poulios E, Trougakos I, Gonos E. Comparative effects of hypoxia on normal and immortalized human diploid fibroblasts. Anticancer Res. 2006;26:2165-8 pubmed

Madrigal Velázquez M, Avilés A, Neri N, Huerta J, Martínez Jaramillo G, Mayani H. Expression of ice, bcl-2, c-myc and p53 in different bone marrow cell populations from patients with diffuse large B-cell lymphoma. Leuk Lymphoma. 2006;47:665-73 pubmed

Mohamed S, Hanke T, Erasmi A, Bechtel M, Scharfschwerdt M, Meissner C, et al. Mitochondrial DNA deletions and the aging heart. Exp Gerontol. 2006;41:508-17 pubmed

Upreti M, Lyle C, Skaug B, Du L, Chambers T. Vinblastine-induced apoptosis is mediated by discrete alterations in subcellular location, oligomeric structure, and activation status of specific Bcl-2 family members. J Biol Chem. 2006;281:15941-50 pubmed

Dumay A, Laulier C, Bertrand P, Saintigny Y, Lebrun F, Vayssiere J, et al. Bax and Bid, two proapoptotic Bcl-2 family members, inhibit homologous recombination, independently of apoptosis regulation. Oncogene. 2006;25:3196-205 pubmed

Basset O, Boittin F, Cognard C, Constantin B, Ruegg U. Bcl-2 overexpression prevents calcium overload and subsequent apoptosis in dystrophic myotubes. Biochem J. 2006;395:267-76 pubmed

Gonzalez Martinez T, Monjil D, Aguado Barrios A, Cobo J, Germana G, Vega J. Bcl-2 immunoreactivity in human cutaneous Meissner and Pacinian corpuscles. Neurosci Lett. 2006;394:13-6 pubmed

Ranga R, Sowmyalakshmi S, Burikhanov R, Akbarsha M, Chendil D. A herbal medicine for the treatment of lung cancer. Mol Cell Biochem. 2005;280:125-33 pubmed

Kurbanov B, Geilen C, Fecker L, Orfanos C, Eberle J. Efficient TRAIL-R1/DR4-mediated apoptosis in melanoma cells by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). J Invest Dermatol. 2005;125:1010-9 pubmed

Soucek K, Pachernik J, Kubala L, Vondracek J, Hofmanova J, Kozubik A. Transforming growth factor-beta1 inhibits all-trans retinoic acid-induced apoptosis. Leuk Res. 2006;30:607-23 pubmed

Pereira A, Strasberg Rieber M, Rieber M. Invasion-associated MMP-2 and MMP-9 are up-regulated intracellularly in concert with apoptosis linked to melanoma cell detachment. Clin Exp Metastasis. 2005;22:285-95 pubmed

Balakrishnan K, Wierda W, Keating M, Gandhi V. Mechanisms of cell death of chronic lymphocytic leukemia lymphocytes by RNA-directed agent, 8-NH2-adenosine. Clin Cancer Res. 2005;11:6745-52 pubmed

Gerbaulet A, Hartmann K, Mekori Y. Mast cell apoptosis. Methods Mol Biol. 2006;315:407-23 pubmed

Ryu J, Lee W, Lee K, Hwang J, Kim Y, Yoon Y, et al. SK-7041, a new histone deacetylase inhibitor, induces G2-M cell cycle arrest and apoptosis in pancreatic cancer cell lines. Cancer Lett. 2006;237:143-54 pubmed

Lee C, Liao C, Lin Y. Flavivirus activates phosphatidylinositol 3-kinase signaling to block caspase-dependent apoptotic cell death at the early stage of virus infection. J Virol. 2005;79:8388-99 pubmed publisher

Lemonnier L, Lazarenko R, Shuba Y, Thebault S, Roudbaraki M, Lepage G, et al. Alterations in the regulatory volume decrease (RVD) and swelling-activated Cl- current associated with neuroendocrine differentiation of prostate cancer epithelial cells. Endocr Relat Cancer. 2005;12:335-49 pubmed

Papazisis K, Kalemi T, Zambouli D, Geromichalos G, Lambropoulos A, Kotsis A, et al. Synergistic effects of protein tyrosine kinase inhibitor genistein with camptothecins against three cell lines in vitro. Cancer Lett. 2006;233:255-64 pubmed

Jiang Z, Yu P. Involvement of extracellular signal-regulated kinases 1/2 and (phosphoinositide 3-kinase)/Akt signal pathways in acquired resistance against neurotoxin of 6-hydroxydopamine in SH-SY5Y cells following cell-cell interaction with astrocytes. Neuroscience. 2005;133:405-11 pubmed

Balakrishnan K, Stellrecht C, Genini D, Ayres M, Wierda W, Keating M, et al. Cell death of bioenergetically compromised and transcriptionally challenged CLL lymphocytes by chlorinated ATP. Blood. 2005;105:4455-62 pubmed

Wang L, Chen L, Benincosa J, Fortney J, Gibson L. VEGF-induced phosphorylation of Bcl-2 influences B lineage leukemic cell response to apoptotic stimuli. Leukemia. 2005;19:344-53 pubmed

Gosslau A, Chen M, Ho C, Chen K. A methoxy derivative of resveratrol analogue selectively induced activation of the mitochondrial apoptotic pathway in transformed fibroblasts. Br J Cancer. 2005;92:513-21 pubmed

Fecker L, Geilen C, Hossini A, Schwarz C, Fechner H, Bartlett D, et al. Selective induction of apoptosis in melanoma cells by tyrosinase promoter-controlled CD95 ligand overexpression. J Invest Dermatol. 2005;124:221-8 pubmed

Du L, Lyle C, Chambers T. Characterization of vinblastine-induced Bcl-xL and Bcl-2 phosphorylation: evidence for a novel protein kinase and a coordinated phosphorylation/dephosphorylation cycle associated with apoptosis induction. Oncogene. 2005;24:107-17 pubmed

Castedo M, Ferri K, Blanco J, Roumier T, Larochette N, Barretina J, et al. Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation. J Exp Med. 2001;194:1097-110 pubmed