product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
RPA194 (C-1) Antibody
catalog :
sc-48385
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-1
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 6a
Lamaa A, Humbert J, Aguirrebengoa M, Cheng X, Nicolas E, Cote J, et al. Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation. elife. 2020;9: pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 1b
Mangeot P, Risson V, Fusil F, Marnef A, Laurent E, Blin J, et al. Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins. Nat Commun. 2019;10:45 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 4d
  • western blot; human; loading ...; fig 4h
Xing Y, Yao R, Zhang Y, Guo C, Jiang S, Xu G, et al. SLERT Regulates DDX21 Rings Associated with Pol I Transcription. Cell. 2017;169:664-678.e16 pubmed publisher
  • immunocytochemistry; human; 1:50; loading ...; fig 5a
Salmina K, Huna A, Inashkina I, Belyayev A, Krigerts J, Paštová L, et al. Nucleolar aggresomes mediate release of pericentric heterochromatin and nuclear destruction of genotoxically treated cancer cells. Nucleus. 2017;8:205-221 pubmed publisher
  • western blot; human; loading ...; fig 3e
Dass R, Sarshad A, Carson B, Feenstra J, Kaur A, Obrdlik A, et al. Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I. PLoS Genet. 2016;12:e1006217 pubmed publisher
  • western blot; human; 1:1000; fig 2
Cipriani G, Gibbons S, Verhulst P, Choi K, Eisenman S, Hein S, et al. Diabetic Csf1op/op mice lacking macrophages are protected against the development of delayed gastric emptying. Cell Mol Gastroenterol Hepatol. 2016;2:40-47 pubmed
  • immunocytochemistry; human; 1:250
Schraivogel D, Schindler S, Danner J, Kremmer E, Pfaff J, Hannus S, et al. Importin-β facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels. Nucleic Acids Res. 2015;43:7447-61 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Peltonen K, Colis L, Liu H, Jäämaa S, Zhang Z, Af Hällström T, et al. Small molecule BMH-compounds that inhibit RNA polymerase I and cause nucleolar stress. Mol Cancer Ther. 2014;13:2537-46 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Bai B, Moore H, Laiho M. CRM1 and its ribosome export adaptor NMD3 localize to the nucleolus and affect rRNA synthesis. Nucleus. 2013;4:315-25 pubmed publisher
Ide S, Imai R, Ochi H, Maeshima K. Transcriptional suppression of ribosomal DNA with phase separation. Sci Adv. 2020;6: pubmed publisher
Daniel L, Cerutti E, Donnio L, Nonnekens J, Carrat C, Zahova S, et al. Mechanistic insights in transcription-coupled nucleotide excision repair of ribosomal DNA. Proc Natl Acad Sci U S A. 2018;115:E6770-E6779 pubmed publisher
Xie Q, Li C, Song X, Wu L, Jiang Q, Qiu Z, et al. Folate deficiency facilitates recruitment of upstream binding factor to hot spots of DNA double-strand breaks of rRNA genes and promotes its transcription. Nucleic Acids Res. 2017;45:2472-2489 pubmed publisher
Salifou K, Ray S, Verrier L, Aguirrebengoa M, Trouche D, Panov K, et al. The histone demethylase JMJD2A/KDM4A links ribosomal RNA transcription to nutrients and growth factors availability. Nat Commun. 2016;7:10174 pubmed publisher
Stixová L, Sehnalová P, Legartová S, Suchánková J, Hrušková T, Kozubek S, et al. HP1β-dependent recruitment of UBF1 to irradiated chromatin occurs simultaneously with CPDs. Epigenetics Chromatin. 2014;7:39 pubmed publisher
Kodiha M, Salimi A, Wang Y, Stochaj U. Pharmacological AMP kinase activators target the nucleolar organization and control cell proliferation. PLoS ONE. 2014;9:e88087 pubmed publisher
Shen M, Zhou T, Xie W, Ling T, Zhu Q, Zong L, et al. The chromatin remodeling factor CSB recruits histone acetyltransferase PCAF to rRNA gene promoters in active state for transcription initiation. PLoS ONE. 2013;8:e62668 pubmed publisher
Grierson P, Acharya S, Groden J. Collaborating functions of BLM and DNA topoisomerase I in regulating human rDNA transcription. Mutat Res. 2013;743-744:89-96 pubmed publisher
Wang W, Chen Z, Mao Z, Zhang H, Ding X, Chen S, et al. Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes. EMBO Rep. 2011;12:1160-6 pubmed publisher
Kodiha M, Bański P, Stochaj U. Computer-based fluorescence quantification: a novel approach to study nucleolar biology. BMC Cell Biol. 2011;12:25 pubmed publisher
Horáková A, Bartova E, Galiova G, Uhlírová R, Matula P, Kozubek S. SUV39h-independent association of HP1 beta with fibrillarin-positive nucleolar regions. Chromosoma. 2010;119:227-41 pubmed publisher
product information
Product Name :
RPA194 (C-1) Antibody
Gene Name :
POLR1A
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-48385
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
RPA194
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
1-300 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA