product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
BECN1 (G-11) Antibody
catalog :
sc-48381
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G-11
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:500; loading ...; fig 1h
Feng W, Wang J, Yan X, Zhang Q, Chai L, Wang Q, et al. ERK/Drp1-dependent mitochondrial fission contributes to HMGB1-induced autophagy in pulmonary arterial hypertension. Cell Prolif. 2021;54:e13048 pubmed publisher
  • western blot; mouse; loading ...; fig 6b
Nasiri Ansari N, Nikolopoulou C, Papoutsi K, Kyrou I, Mantzoros C, Kyriakopoulos G, et al. Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE(-/-) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis. Int J Mol Sci. 2021;22: pubmed publisher
  • western blot; human; fig 6
Talarico C, Dattilo V, D Antona L, Barone A, Amodio N, Belviso S, et al. SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells. Oncotarget. 2016;7:15868-84 pubmed publisher
  • western blot; rat; 1:1000; fig 1
Wang L, Hao H, Wang J, Wang X, Zhang S, Du Y, et al. Decreased autophagy: a major factor for cardiomyocyte death induced by β1-adrenoceptor autoantibodies. Cell Death Dis. 2015;6:e1862 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 6e
Di Cristofori A, Ferrero S, Bertolini I, Gaudioso G, Russo M, Berno V, et al. The vacuolar H+ ATPase is a novel therapeutic target for glioblastoma. Oncotarget. 2015;6:17514-31 pubmed
  • western blot; mouse; fig 1
Kim Y, Kang Y, Lee N, Kim K, Hwang Y, Kim H, et al. Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency. Autophagy. 2015;11:796-811 pubmed publisher
  • western blot; human; 1:800; fig 2
Chen Y, Li X, Guo L, Wu X, He C, Zhang S, et al. Combining radiation with autophagy inhibition enhances suppression of tumor growth and angiogenesis in esophageal cancer. Mol Med Rep. 2015;12:1645-52 pubmed publisher
  • immunocytochemistry; mouse; 1:200; loading ...; fig 6d
  • western blot; mouse; 1:200; loading ...; fig 6a
Young C, Sinadinos A, Lefebvre A, Chan P, Arkle S, Vaudry D, et al. A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90. Autophagy. 2015;11:113-30 pubmed publisher
Zambrano J, Eblen S, Abt M, Rhett J, Muise Helmericks R, Yeh E. HUNK Phosphorylates Rubicon to Support Autophagy. Int J Mol Sci. 2019;20: pubmed publisher
Wang J, Lu K, Liang F, Li X, Wang L, Yang C, et al. Decreased autophagy contributes to myocardial dysfunction in rats subjected to nonlethal mechanical trauma. PLoS ONE. 2013;8:e71400 pubmed publisher
Fang L, Zhou Y, Cao H, Wen P, Jiang L, He W, et al. Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury. PLoS ONE. 2013;8:e60546 pubmed publisher
Zhou J, Freeman T, Ahmad F, Shang X, Mangano E, Gao E, et al. GSK-3? is a central regulator of age-related pathologies in mice. J Clin Invest. 2013;123:1821-32 pubmed publisher
Xi H, Barredo J, Merchan J, Lampidis T. Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKK? leading to autophagy. Biochem Pharmacol. 2013;85:1463-77 pubmed publisher
Mo Z, Fang Y, He Y, Ke X. Change of Beclin-1 dependent on ATP, [Ca(2+)](i) and MMP in PC12 cells following oxygen-glucose deprivation-reoxygenation injury. Cell Biol Int. 2012;36:1043-8 pubmed publisher
Mo Z, Fang Y, He Y, Zhang S. ?-Asarone protects PC12 cells against OGD/R-induced injury via attenuating Beclin-1-dependent autophagy. Acta Pharmacol Sin. 2012;33:737-42 pubmed publisher
Giatromanolaki A, Koukourakis M, Koutsopoulos A, Chloropoulou P, Liberis V, Sivridis E. High Beclin 1 expression defines a poor prognosis in endometrial adenocarcinomas. Gynecol Oncol. 2011;123:147-51 pubmed publisher
Dong L, Hou Y, Tan Y, Tang L, Pan Y, Wang M, et al. Prognostic significance of Beclin 1 in intrahepatic cholangiocellular carcinoma. Autophagy. 2011;7:1222-9 pubmed publisher
Hou Y, Dong L, Tan Y, Yang G, Pan Y, Li Z, et al. Inhibition of active autophagy induces apoptosis and increases chemosensitivity in cholangiocarcinoma. Lab Invest. 2011;91:1146-57 pubmed publisher
product information
Product Name :
BECN1 (G-11) Antibody
Gene Name :
BECN1
Size :
200 µg/ml
Catalog Number :
sc-48381
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
BECN1
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
1-300 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA