product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
PXR (H-11) Antibody
catalog :
sc-48340
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H-11
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4d
Oladimeji P, Lin W, Brewer C, Chen T. Glucose-dependent regulation of pregnane X receptor is modulated by AMP-activated protein kinase. Sci Rep. 2017;7:46751 pubmed publisher
  • western blot; mouse; fig 1
Cui W, Sun M, Galeva N, Williams T, Azuma Y, Staudinger J. SUMOylation and Ubiquitylation Circuitry Controls Pregnane X Receptor Biology in Hepatocytes. Drug Metab Dispos. 2015;43:1316-25 pubmed publisher
  • western blot; human; 1:500
Smutny T, Bitman M, Urban M, Dubecka M, Vrzal R, Dvorak Z, et al. U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells. Arch Toxicol. 2014;88:2243-59 pubmed publisher
Wang C, Xu W, Zhang Y, Huang D, Huang K. Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity. Cell Death Dis. 2018;9:819 pubmed publisher
Doricakova A, Novotna A, Vrzal R, Pavek P, Dvorak Z. The role of residues T248, Y249 and T422 in the function of human pregnane X receptor. Arch Toxicol. 2013;87:291-301 pubmed publisher
Staudinger J, Xu C, Biswas A, Mani S. Post-translational modification of pregnane x receptor. Pharmacol Res. 2011;64:4-10 pubmed publisher
Chen Y, Tang Y, Chen S, Nie D. Regulation of drug resistance by human pregnane X receptor in breast cancer. Cancer Biol Ther. 2009;8:1265-72 pubmed
product information
Product Name :
PXR (H-11) Antibody
Gene Name :
NR1I2
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-48340
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
PXR
reactive species  :
human
Application :
WB, IP, IF, ELISA
Epitope :
101-260 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA