product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
beta-Actin (C4) Antibody
catalog :
sc-47778
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C4
reactivity :
guinea pig, carp, kangaroo rats, fission yeast, hamsters, African green monkey, human, mouse, rat, dogs, chicken, bovine, pigs , fruit fly , domestic sheep, Xenopus laevis, domestic rabbit, roundworm , rhesus macaque
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - free floating section
citations: 1790
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 5s6b
Murata K, Nakatsugawa M, Rahman M, Nguyen L, Millar D, Mulder D, et al. Landscape mapping of shared antigenic epitopes and their cognate TCRs of tumor-infiltrating T lymphocytes in melanoma. elife. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig 1
Lochab S, Singh Y, Sengupta S, Nandicoori V. Mycobacterium tuberculosis exploits host ATM kinase for survival advantage through SecA2 secretome. elife. 2020;9: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4d
Shen H, Gan P, Wang K, Darehzereshki A, Wang K, Kumar S, et al. Mononuclear diploid cardiomyocytes support neonatal mouse heart regeneration in response to paracrine IGF2 signaling. elife. 2020;9: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3d
Zhang J, Huang J, Zhang Y, Zhang X, Zhao L, Li C, et al. Microtubule associated protein 9 inhibits liver tumorigenesis by suppressing ERCC3. EBioMedicine. 2020;53:102701 pubmed publisher
  • western blot; mouse; loading ...; fig 5c
Kim H, Takegahara N, Walsh M, Middleton S, Yu J, Shirakawa J, et al. IgSF11 regulates osteoclast differentiation through association with the scaffold protein PSD-95. Bone Res. 2020;8:5 pubmed publisher
  • western blot; mouse; loading ...; fig 2b
Yang S, Ma C, Wu H, Zhang H, Yuan F, Yang G, et al. Tectorigenin attenuates diabetic nephropathy by improving vascular endothelium dysfunction through activating AdipoR1/2 pathway. Pharmacol Res. 2020;153:104678 pubmed publisher
  • western blot; human; 1:3000; loading ...; fig 5d
Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, et al. YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology. Nat Commun. 2020;11:507 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Li J, Chiu J, Ramanjulu M, Blass B, Pratico D. A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles. Mol Neurodegener. 2020;15:1 pubmed publisher
  • western blot; human; loading ...; fig 1a
Lin C, Lin W, Cho R, Yang C, Yeh Y, Hsiao L, et al. Induction of HO-1 by Mevastatin Mediated via a Nox/ROS-Dependent c-Src/PDGFRα/PI3K/Akt/Nrf2/ARE Cascade Suppresses TNF-α-Induced Lung Inflammation. J Clin Med. 2020;9: pubmed publisher
  • western blot; mouse; 1:1000; loading ...
Budzik J, Swaney D, Jimenez Morales D, Johnson J, Garelis N, Repasy T, et al. Dynamic post-translational modification profiling of Mycobacterium tuberculosis-infected primary macrophages. elife. 2020;9: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2c
Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, et al. Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation. Nat Immunol. 2020;21:30-41 pubmed publisher
  • western blot; human; loading ...; fig s7a
Lundby A, Franciosa G, Emdal K, Refsgaard J, Gnosa S, Bekker Jensen D, et al. Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites. Cell. 2019;179:543-560.e26 pubmed publisher
  • western blot; mouse; loading ...; fig 2b
Deng Q, Li P, Che M, Liu J, Biswas S, Ma G, et al. Activation of hedgehog signaling in mesenchymal stem cells induces cartilage and bone tumor formation via Wnt/β-Catenin. elife. 2019;8: pubmed publisher
  • western blot; human; 1:5000; loading ...; fig 1b
Zhang L, Feng Q, Wang Z, Liu P, Cui S. Progesterone receptor antagonist provides palliative effects for uterine leiomyoma through a Bcl-2/Beclin1-dependent mechanism. Biosci Rep. 2019;39: pubmed publisher
  • western blot; mouse; 1:20,000; loading ...; fig 6f
Jung S, Choe S, Woo H, Jeong H, An H, Moon H, et al. Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits. Autophagy. 2019;:1-19 pubmed publisher
  • western blot; human; loading ...; fig 4c
Sharif H, Wang L, Wang W, Magupalli V, Andreeva L, Qiao Q, et al. Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome. Nature. 2019;: pubmed publisher
  • western blot; mouse; 1:5000; loading ...; fig 2c
An D, Fujiki R, Iannitelli D, Smerdon J, Maity S, Rose M, et al. Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig 2c
Zhang W, Wang G, Xu Z, Tu H, Hu F, Dai J, et al. Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS. Cell. 2019;: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 7a
Fernández Chacón M, Casquero García V, Luo W, Francesca Lunella F, Ferreira Rocha S, Del Olmo Cabrera S, et al. iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications. Nat Commun. 2019;10:2262 pubmed publisher
  • western blot; fruit fly ; 1:50; loading ...; fig 3c
Figard L, Zheng L, Biel N, Xue Z, Seede H, COLEMAN S, et al. Cofilin-Mediated Actin Stress Response Is Maladaptive in Heat-Stressed Embryos. Cell Rep. 2019;26:3493-3501.e4 pubmed publisher
  • western blot; human; loading ...; fig 2a
Liu W, Wang G, Palovcak A, Li Y, Hao S, Liu Z, et al. Impeding the single-strand annealing pathway of DNA double-strand break repair by withaferin A-mediated FANCA degradation. DNA Repair (Amst). 2019;77:10-17 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2a
Fu Y, Zhu J, Zhang Y, Liu Z, Su H, Kong J. Vitamin D Regulates the Expressions of AQP-1 and AQP-4 in Mice Kidneys. Biomed Res Int. 2019;2019:3027036 pubmed publisher
  • western blot; rat; 1:2000; loading ...; fig 1e
Li J, Liu X, Chen H, Sun Z, Chen H, Wang L, et al. Multi-targeting chemoprevention of Chinese herb formula Yanghe Huayan decoction on experimentally induced mammary tumorigenesis. BMC Complement Altern Med. 2019;19:48 pubmed publisher
  • western blot; mouse; loading ...; fig 1a
Srikanth S, Woo J, Wu B, El Sherbiny Y, Leung J, Chupradit K, et al. The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum. Nat Immunol. 2019;20:152-162 pubmed publisher
  • western blot; human; loading ...; fig s6b
Oakes B, Fellmann C, Rishi H, Taylor K, Ren S, Nadler D, et al. CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification. Cell. 2019;176:254-267.e16 pubmed publisher
  • western blot; human; loading ...; fig 1d
Chae Y, Kim J, Park J, Kim K, Oh H, Lee K, et al. FOXO1 degradation via G9a-mediated methylation promotes cell proliferation in colon cancer. Nucleic Acids Res. 2019;47:1692-1705 pubmed publisher
  • western blot; human; loading ...; fig 3e
Theisen D, Davidson J, Briseño C, Gargaro M, Lauron E, Wang Q, et al. WDFY4 is required for cross-presentation in response to viral and tumor antigens. Science. 2018;362:694-699 pubmed publisher
  • western blot; mouse; loading ...; fig 2e
Shang X, Shen C, Liu J, Tang L, Zhang H, Wang Y, et al. Serine protease PRSS55 is crucial for male mouse fertility via affecting sperm migration and sperm-egg binding. Cell Mol Life Sci. 2018;75:4371-4384 pubmed publisher
  • western blot; human; 1:1000; fig 2c
Grevet J, Lan X, Hamagami N, Edwards C, Sankaranarayanan L, Ji X, et al. Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells. Science. 2018;361:285-290 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 1a
Xie Y, Ma W, Meng J, Ren X. Knockdown of ZFPL1 results in increased autophagy and autophagy‑related cell death in NCI‑N87 and BGC‑823 human gastric carcinoma cell lines. Mol Med Rep. 2017;15:2633-2642 pubmed publisher
  • western blot; human; fig 2
Arora R, Sawney S, Saini V, Steffi C, Tiwari M, Saluja D. Esculetin induces antiproliferative and apoptotic response in pancreatic cancer cells by directly binding to KEAP1. Mol Cancer. 2016;15:64 pubmed
  • western blot; human; fig 1
Lorenzen I, Lokau J, Korpys Y, Oldefest M, Flynn C, Künzel U, et al. Control of ADAM17 activity by regulation of its cellular localisation. Sci Rep. 2016;6:35067 pubmed publisher
  • western blot; rat; 1:4000; fig 2
Liao F, Li G, Yuan W, Chen Y, Zuo Y, Rashid K, et al. LSKL peptide alleviates subarachnoid fibrosis and hydrocephalus by inhibiting TSP1-mediated TGF-?1 signaling activity following subarachnoid hemorrhage in rats. Exp Ther Med. 2016;12:2537-2543 pubmed
  • western blot; mouse; fig 2
  • western blot; human; fig 4
Wang H, Han X, Bretz C, Becker S, Gambhir D, Smith G, et al. Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization. Mol Ther Methods Clin Dev. 2016;3:16056 pubmed publisher
  • western blot; human; 1:200; fig 2
Wu Y, Zhang J, Zhang H, Zhai Y. Hepatitis B virus X protein mediates yes-associated protein 1 upregulation in hepatocellular carcinoma. Oncol Lett. 2016;12:1971-1974 pubmed
  • western blot; human; fig 5
Lee J, Jung H, Han Y, Yoon Y, Yun C, Sun H, et al. Antioxidant effects of Cirsium setidens extract on oxidative stress in human mesenchymal stem cells. Mol Med Rep. 2016;14:3777-84 pubmed publisher
  • western blot; human; fig s3
Jeong O, Chae Y, Jung H, Park S, Cho S, Kook H, et al. Long noncoding RNA linc00598 regulates CCND2 transcription and modulates the G1 checkpoint. Sci Rep. 2016;6:32172 pubmed publisher
  • western blot; mouse; fig 4
Guo L, Costanzo Garvey D, Smith D, Zavorka M, Venable Kang M, MacDonald R, et al. Cell non-autonomous regulation of hepatic IGF-1 and neonatal growth by Kinase Suppressor of Ras 2 (KSR2). Sci Rep. 2016;6:32093 pubmed publisher
  • western blot; mouse; 1:2500; fig 4
Suman S, Kumar S, Fornace A, Datta K. Space radiation exposure persistently increased leptin and IGF1 in serum and activated leptin-IGF1 signaling axis in mouse intestine. Sci Rep. 2016;6:31853 pubmed publisher
  • immunoprecipitation; mouse; 1:1000; fig s7
Fujita K, Motoki K, Tagawa K, Chen X, Hama H, Nakajima K, et al. HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease. Sci Rep. 2016;6:31895 pubmed publisher
  • western blot; human; fig 1
Rey G, Valekunja U, Feeney K, Wulund L, Milev N, Stangherlin A, et al. The Pentose Phosphate Pathway Regulates the Circadian Clock. Cell Metab. 2016;24:462-473 pubmed publisher
  • western blot; mouse; 1:1000; fig s5
Klose R, Krzywinska E, Castells M, Gotthardt D, Putz E, Kantari Mimoun C, et al. Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia. Nat Commun. 2016;7:12528 pubmed publisher
  • immunoprecipitation; roundworm ; 1:5000; fig s2
Wei Q, Zhang Y, Schouteden C, Zhang Y, Zhang Q, Dong J, et al. The hydrolethalus syndrome protein HYLS-1 regulates formation of the ciliary gate. Nat Commun. 2016;7:12437 pubmed publisher
  • western blot; human; fig 1
Turchinovich A, Surowy H, Tonevitsky A, Burwinkel B. Interference in transcription of overexpressed genes by promoter-proximal downstream sequences. Sci Rep. 2016;6:30735 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Wang Z, Zhang H, Sun X, Ren L. The protective role of vitamin D3 in a murine model of asthma via the suppression of TGF-?/Smad signaling and activation of the Nrf2/HO-1 pathway. Mol Med Rep. 2016;14:2389-96 pubmed publisher
  • western blot; human; 1:1000; fig 1
Anta B, Pérez Rodríguez A, Castro J, García Domínguez C, Ibiza S, Martínez N, et al. PGA1-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes. Cell Death Dis. 2016;7:e2311 pubmed publisher
  • western blot; mouse; fig 7
Pang J, Wu Y, Peng J, Yang P, Kuai L, Qin X, et al. Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: Involvement in the modulation of blood-brain barrier integrity. Oncotarget. 2016;7:56030-56044 pubmed publisher
  • western blot; human; fig 5
Jeong H, Cho Y, Kim K, Kim Y, Kim K, Na Y, et al. Anti-lipoapoptotic effects of Alisma orientalis extract on non-esterified fatty acid-induced HepG2 cells. BMC Complement Altern Med. 2016;16:239 pubmed publisher
  • western blot; human; fig 3
Tsuboki J, Fujiwara Y, Horlad H, Shiraishi D, Nohara T, Tayama S, et al. Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages. Sci Rep. 2016;6:29588 pubmed publisher
  • western blot; human; 1:2500; fig s2
Deblois G, Smith H, Tam I, Gravel S, Caron M, Savage P, et al. ERR? mediates metabolic adaptations driving lapatinib resistance in breast cancer. Nat Commun. 2016;7:12156 pubmed publisher
  • western blot; mouse; 1:5000; fig 5
Schokrpur S, Hu J, Moughon D, Liu P, Lin L, Hermann K, et al. CRISPR-Mediated VHL Knockout Generates an Improved Model for Metastatic Renal Cell Carcinoma. Sci Rep. 2016;6:29032 pubmed publisher
  • western blot; human; fig 4
  • western blot; mouse; fig 6
Dai L, Cui X, Zhang X, Cheng L, Liu Y, Yang Y, et al. SARI inhibits angiogenesis and tumour growth of human colon cancer through directly targeting ceruloplasmin. Nat Commun. 2016;7:11996 pubmed publisher
  • western blot; human; 1:400; fig 3
Eterno V, Zambelli A, Villani L, Tuscano A, Manera S, Spitaleri A, et al. AurkA controls self-renewal of breast cancer-initiating cells promoting wnt3a stabilization through suppression of miR-128. Sci Rep. 2016;6:28436 pubmed publisher
  • western blot; human; 1:1000; fig s5
Hong A, Tseng Y, Cowley G, Jonas O, Cheah J, Kynnap B, et al. Integrated genetic and pharmacologic interrogation of rare cancers. Nat Commun. 2016;7:11987 pubmed publisher
  • western blot; mouse; 1:200; fig s4
Nakashima H, Ohkawara B, Ishigaki S, Fukudome T, Ito K, Tsushima M, et al. R-spondin 2 promotes acetylcholine receptor clustering at the neuromuscular junction via Lgr5. Sci Rep. 2016;6:28512 pubmed publisher
  • western blot; rat; 1:1000; fig 5
Yu H, Shi L, Qi G, Zhao S, Gao Y, Li Y. Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo. Front Pharmacol. 2016;7:148 pubmed publisher
  • western blot; mouse; fig 6
  • western blot; human; fig 4
Kuramoto K, Wang N, Fan Y, Zhang W, Schoenen F, Frankowski K, et al. Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids. Autophagy. 2016;12:1460-71 pubmed publisher
  • western blot; rat; fig 1
Zhai W, Chen D, Shen H, Chen Z, Li H, Yu Z, et al. A1 adenosine receptor attenuates intracerebral hemorrhage-induced secondary brain injury in rats by activating the P38-MAPKAP2-Hsp27 pathway. Mol Brain. 2016;9:66 pubmed publisher
  • western blot; human; 1:500; fig 4
Han L, Guo X, Bian H, Yang L, Chen Z, Zang W, et al. Guizhi Fuling Wan, a Traditional Chinese Herbal Formula, Sensitizes Cisplatin-Resistant Human Ovarian Cancer Cells through Inactivation of the PI3K/AKT/mTOR Pathway. Evid Based Complement Alternat Med. 2016;2016:4651949 pubmed publisher
  • western blot; mouse; loading ...; fig 2d
Nakagawa Y, Oikawa F, Mizuno S, Ohno H, Yagishita Y, Satoh A, et al. Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system. Sci Rep. 2016;6:27857 pubmed publisher
  • western blot; human; fig 1
Zhou X, Hao Q, Liao P, Luo S, Zhang M, Hu G, et al. Nerve growth factor receptor negates the tumor suppressor p53 as a feedback regulator. elife. 2016;5: pubmed publisher
  • western blot; human; 1:5000; fig 6
Zhao X, Wang J, Xiao L, Xu Q, Zhao E, Zheng X, et al. Effects of 17-AAG on the cell cycle and apoptosis of H446 cells and the associated mechanisms. Mol Med Rep. 2016;14:1067-74 pubmed publisher
  • western blot; mouse; 1:5000; fig 1
Wang J, Farris A, Xu K, Wang P, Zhang X, Duong D, et al. GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesis. Nat Commun. 2016;7:11795 pubmed publisher
  • western blot; human; fig 4
Ansari M, Haqqi T. Interleukin-1β induced Stress Granules Sequester COX-2 mRNA and Regulates its Stability and Translation in Human OA Chondrocytes. Sci Rep. 2016;6:27611 pubmed publisher
  • western blot; mouse; fig 2
Nwadozi E, Roudier E, Rullman E, Tharmalingam S, Liu H, Gustafsson T, et al. Endothelial FoxO proteins impair insulin sensitivity and restrain muscle angiogenesis in response to a high-fat diet. FASEB J. 2016;30:3039-52 pubmed publisher
  • western blot; human; fig 1
Huang S, Jiang M, Chen G, Qian K, Gao H, Guan W, et al. Epigenetic Silencing of Eyes Absent 4 Gene by Acute Myeloid Leukemia 1-Eight-twenty-one Oncoprotein Contributes to Leukemogenesis in t(8;21) Acute Myeloid Leukemia. Chin Med J (Engl). 2016;129:1355-62 pubmed publisher
  • western blot; human; fig 10
Lehner C, Gehwolf R, Ek J, Korntner S, Bauer H, Bauer H, et al. The blood-tendon barrier: identification and characterisation of a novel tissue barrier in tendon blood vessels. Eur Cell Mater. 2016;31:296-311 pubmed
  • western blot; human; fig 1
Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;291:14761-72 pubmed publisher
  • western blot; mouse; fig 1
Gu X, Liu X, Chen Y, Zhao Y, Xu M, Han X, et al. Involvement of NADPH oxidases in alkali burn-induced corneal injury. Int J Mol Med. 2016;38:75-82 pubmed publisher
  • western blot; domestic sheep; 1:1000; fig 5
Herman A, Bochenek J, Krol K, Krawczynska A, Antushevich H, Pawlina B, et al. Central Interleukin-1? Suppresses the Nocturnal Secretion of Melatonin. Mediators Inflamm. 2016;2016:2589483 pubmed publisher
  • western blot; mouse; fig 8
Lu J, Ji W, Zhao M, Wang M, Yan W, Chen M, et al. Protamine zinc insulin combined with sodium selenite improves glycometabolism in the diabetic KKAy mice. Sci Rep. 2016;6:26563 pubmed publisher
  • western blot; human; fig 1
Hou Z, Zhang J, Han Q, Su C, Qu J, Xu D, et al. Hepatitis B virus inhibits intrinsic RIG-I and RIG-G immune signaling via inducing miR146a. Sci Rep. 2016;6:26150 pubmed publisher
  • western blot; human; fig 3
Sun Y, Hu W, Yu X, Liu Z, Tarran R, Ravid K, et al. Actinin-1 binds to the C-terminus of A2B adenosine receptor (A2BAR) and enhances A2BAR cell-surface expression. Biochem J. 2016;473:2179-86 pubmed publisher
  • western blot; human; fig 1
Zhang X, Adderley S, Breslin J. Activation of RhoA, but Not Rac1, Mediates Early Stages of S1P-Induced Endothelial Barrier Enhancement. PLoS ONE. 2016;11:e0155490 pubmed publisher
  • western blot; human; 1:2000; fig 3
Karlas A, Berrè S, Couderc T, Varjak M, Braun P, Meyer M, et al. A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs. Nat Commun. 2016;7:11320 pubmed publisher
  • western blot; rat; fig 10
  • western blot; mouse; fig 8
Song J, Sun Y, Peluso I, Zeng Y, Yu X, Lu J, et al. A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition. Autophagy. 2016;12:1372-89 pubmed publisher
  • western blot; human; fig 3B
Kwon O, Kim K, Lee E, Kim M, Choi S, Li H, et al. Induction of MiR-21 by Stereotactic Body Radiotherapy Contributes to the Pulmonary Fibrotic Response. PLoS ONE. 2016;11:e0154942 pubmed publisher
  • western blot; mouse; fig 5
Martin G, Chung S, Landrock D, Landrock K, Huang H, Dangott L, et al. FABP-1 gene ablation impacts brain endocannabinoid system in male mice. J Neurochem. 2016;138:407-22 pubmed publisher
  • western blot; mouse; fig s1
Lee B, Wu C, Lin Y, Park S, Wei L. Synergistic activation of Arg1 gene by retinoic acid and IL-4 involves chromatin remodeling for transcription initiation and elongation coupling. Nucleic Acids Res. 2016;44:7568-79 pubmed publisher
  • western blot; pigs ; fig 6
Ren W, Yin J, Chen S, Duan J, Liu G, Li T, et al. Proteome analysis for the global proteins in the jejunum tissues of enterotoxigenic Escherichia coli -infected piglets. Sci Rep. 2016;6:25640 pubmed publisher
  • western blot; human; tbl 1
Lombardo G, Dentelli P, Togliatto G, Rosso A, Gili M, Gallo S, et al. Activated Stat5 trafficking Via Endothelial Cell-derived Extracellular Vesicles Controls IL-3 Pro-angiogenic Paracrine Action. Sci Rep. 2016;6:25689 pubmed publisher
  • western blot; African green monkey; fig 3
Geissler R, Simkin A, Floss D, Patel R, Fogarty E, Scheller J, et al. A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1. Genes Dev. 2016;30:1070-85 pubmed publisher
  • western blot; human; 1:1000; fig 1
Alaee M, Danesh G, Pasdar M. Plakoglobin Reduces the in vitro Growth, Migration and Invasion of Ovarian Cancer Cells Expressing N-Cadherin and Mutant p53. PLoS ONE. 2016;11:e0154323 pubmed publisher
  • western blot; rat; 1:100; fig 7
Xiao X, Chang G, Liu J, Sun G, Liu L, Qin S, et al. Simvastatin ameliorates ventricular remodeling via the TGF??1 signaling pathway in rats following myocardial infarction. Mol Med Rep. 2016;13:5093-101 pubmed publisher
  • western blot; rat; 1:2000; fig 4
Jeong J, Noh M, Choi J, Lee H, Kim S. Neuroprotective and antioxidant activities of bamboo salt soy sauce against H2O2-induced oxidative stress in rat cortical neurons. Exp Ther Med. 2016;11:1201-1210 pubmed
  • western blot; human; 1:400; fig 1
Wang Y, Gratzke C, Tamalunas A, Wiemer N, Ciotkowska A, Rutz B, et al. P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate. PLoS ONE. 2016;11:e0153312 pubmed publisher
  • western blot; mouse; fig 4
Yang E, Ahn S, Lee K, Mahmood U, Kim H. Early Behavioral Abnormalities and Perinatal Alterations of PTEN/AKT Pathway in Valproic Acid Autism Model Mice. PLoS ONE. 2016;11:e0153298 pubmed publisher
  • western blot; human; fig 1
  • western blot; mouse; fig 4
Zhuang H, Tian W, Li W, Zhang X, Wang J, Yang Y, et al. Autophagic Cell Death and Apoptosis Jointly Mediate Cisatracurium Besylate-Induced Cell Injury. Int J Mol Sci. 2016;17:515 pubmed publisher
  • western blot; human; 1:1000; fig 5
Ojala M, Prajapati C, Pölönen R, Rajala K, Pekkanen Mattila M, Rasku J, et al. Mutation-Specific Phenotypes in hiPSC-Derived Cardiomyocytes Carrying Either Myosin-Binding Protein C Or α-Tropomyosin Mutation for Hypertrophic Cardiomyopathy. Stem Cells Int. 2016;2016:1684792 pubmed publisher
  • western blot; human; fig 1
Shi J, CUI N, Wang S, Zhao M, Wang B, Wang Y, et al. Overexpression of YB1 C-terminal domain inhibits proliferation, angiogenesis and tumorigenicity in a SK-BR-3 breast cancer xenograft mouse model. FEBS Open Bio. 2016;6:33-42 pubmed publisher
  • western blot; human; fig 3
Popek S, Kapka Skrzypczak L, Sawicki K, Wolinska E, Skrzypczak M, Czajka M. IL?6 and IL?8 enhance factor H binding to the cell membranes. Mol Med Rep. 2016;13:3886-94 pubmed publisher
  • western blot; human; 1:1000; fig 5
Jiang Y, Wang X, Li Y, Mu S, Zhou S, Liu Y, et al. GGsTOP increases migration of human periodontal ligament cells in vitro via reactive oxygen species pathway. Mol Med Rep. 2016;13:3813-20 pubmed publisher
  • western blot; mouse; 1:1000; fig 7
Xing R, Zhang Y, Xu H, Luo X, Chang R, Liu J, et al. Spatial memory impairment by TRPC1 depletion is ameliorated by environmental enrichment. Oncotarget. 2016;7:27855-73 pubmed publisher
  • western blot; human; 1:10,000; fig 6
Ding Z, Jin G, Wang W, Sun Y, Chen W, Chen L, et al. Activin A-Smad Signaling Mediates Connective Tissue Growth Factor Synthesis in Liver Progenitor Cells. Int J Mol Sci. 2016;17:408 pubmed publisher
  • western blot; human; fig 2
Dai Y, Wang L, Tang J, Cao P, Luo Z, Sun J, et al. Activation of anaphase-promoting complex by p53 induces a state of dormancy in cancer cells against chemotherapeutic stress. Oncotarget. 2016;7:25478-92 pubmed publisher
  • western blot; human; 1:500; fig 5
Li B, Chen D, Li W, Xiao D. 20(S)-Protopanaxadiol saponins inhibit SKOV3 cell migration. Oncol Lett. 2016;11:1693-1698 pubmed
  • western blot; mouse; fig s1
Garcia R, Roemmich J, Claycombe K. Evaluation of markers of beige adipocytes in white adipose tissue of the mouse. Nutr Metab (Lond). 2016;13:24 pubmed publisher
  • western blot; human; fig 1
Mukherjee D, Lu H, Yu L, He C, Lahiri S, Li T, et al. Krüppel-like factor 8 activates the transcription of C-X-C cytokine receptor type 4 to promote breast cancer cell invasion, transendothelial migration and metastasis. Oncotarget. 2016;7:23552-68 pubmed publisher
  • western blot; human; 1:2000; fig 4
Tögel L, Nightingale R, Chueh A, Jayachandran A, Tran H, Phesse T, et al. Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells. Mol Cancer Ther. 2016;15:1217-26 pubmed publisher
  • western blot; human; 1:1000; fig 7
Joo M, Park J, Yoo H, Lee B, Chun H, Lee S, et al. The roles of HOXB7 in promoting migration, invasion, and anti-apoptosis in gastric cancer. J Gastroenterol Hepatol. 2016;31:1717-1726 pubmed publisher
  • western blot; human; 1:200; fig 5
Hackler L, Ozsvári B, Gyuris M, Sipos P, Fábián G, Molnar E, et al. The Curcumin Analog C-150, Influencing NF-κB, UPR and Akt/Notch Pathways Has Potent Anticancer Activity In Vitro and In Vivo. PLoS ONE. 2016;11:e0149832 pubmed publisher
  • western blot; human; fig 3b
Singh A, Joshi S, Zulcic M, Alcaraz M, GARLICH J, Morales G, et al. PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma. PLoS ONE. 2016;11:e0150836 pubmed publisher
  • western blot; rat; 1:2000; fig 3
Xu A, Zheng G, Wang Z, Chen X, Jiang Q. Neuroprotective effects of Ilexonin A following transient focal cerebral ischemia in rats. Mol Med Rep. 2016;13:2957-66 pubmed publisher
  • western blot; human; 1:1000; fig 5
Jing H, Sun W, Fan J, Zhang Y, Yang J, Jia J, et al. Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways. Mol Med Rep. 2016;13:3009-16 pubmed publisher
  • western blot; mouse; fig 2
  • western blot; human; fig 4
  • western blot; African green monkey; fig 1
Persaud S, Park S, Ishigami Yuasa M, Koyano Nakagawa N, Kagechika H, Wei L. All trans-retinoic acid analogs promote cancer cell apoptosis through non-genomic Crabp1 mediating ERK1/2 phosphorylation. Sci Rep. 2016;6:22396 pubmed publisher
  • western blot; rat; 1:1000; fig 2
Chen C, Meng S, Xue Y, Han Y, Sun C, Deng J, et al. Epigenetic modification of PKMζ rescues aging-related cognitive impairment. Sci Rep. 2016;6:22096 pubmed publisher
  • western blot; human; 1:1000; fig 1
Chang T, Chen C, Wu Y, Liu J, Kuo Y, Lee K, et al. Inflammation Promotes Expression of Stemness-Related Properties in HBV-Related Hepatocellular Carcinoma. PLoS ONE. 2016;11:e0149897 pubmed publisher
  • western blot; human; fig 3
Lee S, Jeong A, Park J, Han S, Jang C, Kim K, et al. IK-guided PP2A suppresses Aurora B activity in the interphase of tumor cells. Cell Mol Life Sci. 2016;73:3375-86 pubmed publisher
  • western blot; human; fig 1
Golnik R, Lehmann A, Kloetzel P, Ebstein F. Major Histocompatibility Complex (MHC) Class I Processing of the NY-ESO-1 Antigen Is Regulated by Rpn10 and Rpn13 Proteins and Immunoproteasomes following Non-lysine Ubiquitination. J Biol Chem. 2016;291:8805-15 pubmed publisher
  • western blot; human; fig s11
Sancho Martinez I, Nivet E, Xia Y, Hishida T, Aguirre A, Ocampo A, et al. Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. Nat Commun. 2016;7:10743 pubmed publisher
  • western blot; human; 1:200; fig 2
Wang Y, Ha M, Liu J, Li P, Zhang W, Zhang X. Role of BCL2-associated athanogene in resistance to platinum-based chemotherapy in non-small-cell lung cancer. Oncol Lett. 2016;11:984-990 pubmed
  • western blot; rat; 1:10,000; fig 3
Lin Y, Ma Q, Lin S, Zhou H, Wen Q, Gao S, et al. Inhibitory effects of 90Sr/90Y β-irradiation on alkali burn-induced corneal neovascularization in rats. Exp Ther Med. 2016;11:409-414 pubmed
  • western blot; human; fig 1
Kan H, Huang Y, Li X, Liu D, Chen J, Shu M. Zinc finger protein ZBTB20 is an independent prognostic marker and promotes tumor growth of human hepatocellular carcinoma by repressing FoxO1. Oncotarget. 2016;7:14336-49 pubmed publisher
  • western blot; mouse; fig 1
Hwang S, Jang S, Kim M, Kim L, Kim B, Kim H, et al. YY1 inhibits differentiation and function of regulatory T cells by blocking Foxp3 expression and activity. Nat Commun. 2016;7:10789 pubmed publisher
  • western blot; human; fig 5
Haraguchi T, Kondo M, Uchikawa R, Kobayashi K, Hiramatsu H, Kobayashi K, et al. Dynamics and plasticity of the epithelial to mesenchymal transition induced by miR-200 family inhibition. Sci Rep. 2016;6:21117 pubmed publisher
  • western blot; human; 1:1000; fig 3
  • western blot; rat; 1:1000; fig 5
Zhao J, Wang L, Dong X, Hu X, Zhou L, Liu Q, et al. The c-Jun N-terminal kinase (JNK) pathway is activated in human interstitial cystitis (IC) and rat protamine sulfate induced cystitis. Sci Rep. 2016;6:19670 pubmed publisher
  • western blot; human; fig 1
Franciosa G, Diluvio G, Gaudio F, Giuli M, Palermo R, Grazioli P, et al. Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression. Oncogene. 2016;35:4741-51 pubmed publisher
  • western blot; human; 1:1000; fig 5
Zhang Z, Zhang H, Peng T, Li D, Xu J. Melittin suppresses cathepsin S-induced invasion and angiogenesis via blocking of the VEGF-A/VEGFR-2/MEK1/ERK1/2 pathway in human hepatocellular carcinoma. Oncol Lett. 2016;11:610-618 pubmed
  • western blot; human; fig 1
Miao F, Zhu J, Chen Y, Tang N, Wang X, Li X. MicroRNA-183-5p promotes the proliferation, invasion and metastasis of human pancreatic adenocarcinoma cells. Oncol Lett. 2016;11:134-140 pubmed
  • western blot; mouse; 1:2000; loading ...; fig 2a
Wang P, Li L, Zhang Z, Kan Q, Chen S, Gao F. Time-dependent homeostasis between glucose uptake and consumption in astrocytes exposed to CoClâ‚‚ treatment. Mol Med Rep. 2016;13:2909-17 pubmed publisher
  • western blot; human; 1:500; fig 1
Bondy Chorney E, Crawford Parks T, Ravel Chapuis A, Klinck R, Rocheleau L, Pelchat M, et al. Staufen1 Regulates Multiple Alternative Splicing Events either Positively or Negatively in DM1 Indicating Its Role as a Disease Modifier. PLoS Genet. 2016;12:e1005827 pubmed publisher
  • western blot; domestic rabbit; 1:500; fig 4
Lin F, Chen Y, Liang H, Tan S. Echistatin prevents posterior capsule opacification in diabetic rabbit model via integrin linked kinase signaling pathway. Int J Clin Exp Pathol. 2015;8:14294-304 pubmed
  • western blot; human; 1:500; fig 2
Ward A, Mellor P, Smith S, Kendall S, Just N, Vizeacoumar F, et al. Epigenetic silencing of CREB3L1 by DNA methylation is associated with high-grade metastatic breast cancers with poor prognosis and is prevalent in triple negative breast cancers. Breast Cancer Res. 2016;18:12 pubmed publisher
  • western blot; human; 1:1000; fig 3
Koyani C, Kitz K, Rossmann C, Bernhart E, Huber E, Trummer C, et al. Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death. Biochem Pharmacol. 2016;104:29-41 pubmed publisher
  • western blot; human; fig 1
Chung S, Moon H, Ju H, Kim D, Cho K, Ribback S, et al. Comparison of liver oncogenic potential among human RAS isoforms. Oncotarget. 2016;7:7354-66 pubmed publisher
  • western blot; human; fig 2
Deb M, Sengupta D, Kar S, Rath S, Roy S, Das G, et al. Epigenetic drift towards histone modifications regulates CAV1 gene expression in colon cancer. Gene. 2016;581:75-84 pubmed publisher
  • western blot; mouse; 1:1000; fig 6
Sawada S, Chosa N, Takizawa N, Yokota J, Igarashi Y, Tomoda K, et al. Establishment of mesenchymal stem cell lines derived from the bone marrow of green fluorescent protein-transgenic mice exhibiting a diversity in intracellular transforming growth factor-β and bone morphogenetic protein signaling. Mol Med Rep. 2016;13:2023-31 pubmed publisher
  • western blot; human; fig 2d
Grohar P, Kim S, Rangel Rivera G, Sen N, Haddock S, Harlow M, et al. Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma. Cell Rep. 2016;14:598-610 pubmed publisher
  • western blot; human; fig 1
Dai X, Zhuang L, Wang D, Zhou T, Chang L, Gai R, et al. Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells. Oncotarget. 2016;7:6933-47 pubmed publisher
  • western blot; mouse; fig 2
Li W, Zou J, Yue F, Song K, Chen Q, McKeehan W, et al. Defects in MAP1S-mediated autophagy cause reduction in mouse lifespans especially when fibronectin is overexpressed. Aging Cell. 2016;15:370-9 pubmed publisher
  • western blot; human; 1:50,000; fig 1
Gupta Y, Pasupuleti V, Du W, Welford S. Macrophage Migration Inhibitory Factor Secretion Is Induced by Ionizing Radiation and Oxidative Stress in Cancer Cells. PLoS ONE. 2016;11:e0146482 pubmed publisher
  • western blot; human
Phillips S, Soderblom E, Bradrick S, Garcia Blanco M. Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication. MBio. 2016;7:e01865-15 pubmed publisher
  • western blot; rat; fig 3b
Jiang Q, Wang M, Li L, Mo H, Song J, Tang Q, et al. Electroacupuncture relieves labour pain and influences the spinal dynorphin/κ-opioid receptor system in rats. Acupunct Med. 2016;34:223-8 pubmed publisher
  • western blot; rat; 1:1000; fig 1
Wang J, Liang W, Cui Y, He J, Liu H, Wang Y, et al. Noncanonical Activin A Signaling in PC12 Cells: A Self-Limiting Feedback Loop. Neurochem Res. 2016;41:1073-84 pubmed publisher
  • immunohistochemistry; rat
Bishayee A, Mandal A, Bhattacharyya P, Bhatia D. Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis. Nutr Cancer. 2016;68:120-30 pubmed publisher
  • western blot; bovine; fig 1
Ao J, Wei C, Si Y, Luo C, Lv W, Lin Y, et al. Tudor-SN Regulates Milk Synthesis and Proliferation of Bovine Mammary Epithelial Cells. Int J Mol Sci. 2015;16:29936-47 pubmed publisher
  • western blot; mouse; fig 5
Su X, Yan H, Huang Y, Yun H, Zeng B, Wang E, et al. Expression of FABP4, adipsin and adiponectin in Paneth cells is modulated by gut Lactobacillus. Sci Rep. 2015;5:18588 pubmed publisher
  • western blot; Xenopus laevis; fig 5C
  • western blot; human; fig 5A
Overton J, Komiya Y, Mezzacappa C, Nama K, Cai N, Lou L, et al. Hepatocystin is Essential for TRPM7 Function During Early Embryogenesis. Sci Rep. 2015;5:18395 pubmed publisher
  • western blot; human; 1:1000; fig s19
  • western blot; mouse; 1:1000; fig 9
Schrage R, Schmitz A, Gaffal E, Annala S, Kehraus S, Wenzel D, et al. The experimental power of FR900359 to study Gq-regulated biological processes. Nat Commun. 2015;6:10156 pubmed publisher
  • western blot; mouse; fig 2c
Sanchez G, Bondy Chorney E, Laframboise J, Paris G, Didillon A, Jasmin B, et al. A novel role for CARM1 in promoting nonsense-mediated mRNA decay: potential implications for spinal muscular atrophy. Nucleic Acids Res. 2016;44:2661-76 pubmed publisher
  • western blot; human; 1:1000; fig 2
Ying Z, Li X, Dang H, Wang F, Xu X. Effect of Hath1 on the proliferation and apoptosis of cutaneous squamous cell carcinoma in vitro. Mol Med Rep. 2015;12:7845-50 pubmed publisher
  • western blot; fruit fly ; fig 3
Jeong K, Lee S, Seo H, Oh Y, Jang D, Choe J, et al. Ca-α1T, a fly T-type Ca2+ channel, negatively modulates sleep. Sci Rep. 2015;5:17893 pubmed publisher
  • western blot; human; 1:5000; fig 3C
Lin C, Huang P, Lai C, Chen J, Lin S, Chen J. Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1. PLoS ONE. 2015;10:e0143686 pubmed publisher
  • western blot; human; fig 6
Cataldo A, Cheung D, Balsari A, Tagliabue E, Coppola V, Iorio M, et al. miR-302b enhances breast cancer cell sensitivity to cisplatin by regulating E2F1 and the cellular DNA damage response. Oncotarget. 2016;7:786-97 pubmed publisher
  • western blot; human; fig 3
Yang B, Zhang M, Gao J, Li J, Fan L, Xiang G, et al. Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer. Oncotarget. 2015;6:37613-25 pubmed publisher
  • western blot; human; 1:2000; fig 6
Zhou R, Zhou X, Yin Z, Guo J, Hu T, Jiang S, et al. Tumor invasion and metastasis regulated by microRNA-184 and microRNA-574-5p in small-cell lung cancer. Oncotarget. 2015;6:44609-22 pubmed publisher
  • western blot; human; fig 2
Ponti D, Bastianelli D, Rosa P, Pacini L, Ibrahim M, Rendina E, et al. The expression of B23 and EGR1 proteins is functionally linked in tumor cells under stress conditions. BMC Cell Biol. 2015;16:27 pubmed publisher
  • western blot; human; fig 1
Matsunuma R, Niida H, Ohhata T, Kitagawa K, Sakai S, Uchida C, et al. UV Damage-Induced Phosphorylation of HBO1 Triggers CRL4DDB2-Mediated Degradation To Regulate Cell Proliferation. Mol Cell Biol. 2016;36:394-406 pubmed publisher
  • western blot; human; loading ...; fig 2
  • western blot; mouse; loading ...; fig 5a
Song K, Hu W, Yue F, Zou J, Li W, Chen Q, et al. Transforming Growth Factor TGFβ Increases Levels of Microtubule-Associated Protein MAP1S and Autophagy Flux in Pancreatic Ductal Adenocarcinomas. PLoS ONE. 2015;10:e0143150 pubmed publisher
  • western blot; rat; 1:3000; fig 8
Lesmana R, Sinha R, Singh B, Zhou J, Ohba K, Wu Y, et al. Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle. Endocrinology. 2016;157:23-38 pubmed publisher
  • western blot; human; fig 4
Lee J, Park K, Han D, Bang N, Kim D, Na H, et al. PharmDB-K: Integrated Bio-Pharmacological Network Database for Traditional Korean Medicine. PLoS ONE. 2015;10:e0142624 pubmed publisher
  • western blot; human; fig 5
Zhang Z, Wu N, Lu Y, Davidson D, Colonna M, Veillette A. DNAM-1 controls NK cell activation via an ITT-like motif. J Exp Med. 2015;212:2165-82 pubmed publisher
  • western blot; human; fig 1
Ahn H, Kim K, Shin K, Lim K, Kim J, Lee J, et al. Ell3 stabilizes p53 following CDDP treatment via its effects on ubiquitin-dependent and -independent proteasomal degradation pathways in breast cancer cells. Oncotarget. 2015;6:44523-37 pubmed publisher
  • western blot; mouse; 1:2000; fig 2,4,5,6
Hao J, Sun N, Lei L, Li X, Yao B, Sun K, et al. L-Stepholidine rescues memory deficit and synaptic plasticity in models of Alzheimer's disease via activating dopamine D1 receptor/PKA signaling pathway. Cell Death Dis. 2015;6:e1965 pubmed publisher
  • western blot; mouse; fig 6,7
Vernot J, Perdomo Arciniegas A, Pérez Quintero L, Martínez D. Modulating p56Lck in T-Cells by a Chimeric Peptide Comprising Two Functionally Different Motifs of Tip from Herpesvirus saimiri. J Immunol Res. 2015;2015:395371 pubmed publisher
  • western blot; human; 1:1000; fig 2
Riesenberg S, Groetchen A, Siddaway R, Bald T, Reinhardt J, Smorra D, et al. MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment. Nat Commun. 2015;6:8755 pubmed publisher
  • western blot; hamsters; fig 6
Ting W, Kuo W, Hsieh D, Yeh Y, Day C, Chen Y, et al. Heat Killed Lactobacillus reuteri GMNL-263 Reduces Fibrosis Effects on the Liver and Heart in High Fat Diet-Hamsters via TGF-β Suppression. Int J Mol Sci. 2015;16:25881-96 pubmed publisher
  • western blot; human; fig 2a
d Avenia M, Citro R, De Marco M, Veronese A, Rosati A, Visone R, et al. A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy. Cell Death Dis. 2015;6:e1948 pubmed publisher
  • western blot; mouse; 1:1000; fig 1
Wang B, Ma A, Zhang L, Jin W, Qian Y, Xu G, et al. POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation. Nat Commun. 2015;6:8704 pubmed publisher
  • western blot; human; fig 7
Watkinson R, McEwan W, Tam J, Vaysburd M, James L. TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus. PLoS Pathog. 2015;11:e1005253 pubmed publisher
  • western blot; mouse; fig 3
  • western blot; human; fig 3
Shen W, Chang A, Wang J, Zhou W, Gao R, Li J, et al. TIFA, an inflammatory signaling adaptor, is tumor suppressive for liver cancer. Oncogenesis. 2015;4:e173 pubmed publisher
  • western blot; human; fig 3
Qin W, Li C, Zheng W, Guo Q, Zhang Y, Kang M, et al. Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells. Oncotarget. 2015;6:39839-54 pubmed publisher
  • western blot; human; 1:1000; fig 2
Zomerman W, Plasschaert S, Diks S, Lourens H, Meeuwsen de Boer T, Hoving E, et al. Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines. PLoS ONE. 2015;10:e0141381 pubmed publisher
  • western blot; human; fig 1
Lee J, Lee S, Heo S, Kim K, Kim C, Kim D, et al. Novel Function of Lysine Methyltransferase G9a in the Regulation of Sox2 Protein Stability. PLoS ONE. 2015;10:e0141118 pubmed publisher
  • western blot; human; fig 9
Reeder J, Kwak Y, McNamara R, Forst C, D Orso I. HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells. elife. 2015;4: pubmed publisher
  • western blot; human; 1:1000; fig 1B
Ou Yang L, Xiao S, Liu P, Yi S, Zhang X, Ou Yang S, et al. Forkhead box C1 induces epithelial‑mesenchymal transition and is a potential therapeutic target in nasopharyngeal carcinoma. Mol Med Rep. 2015;12:8003-9 pubmed publisher
  • western blot; human
Schmidt T, Schmid Burgk J, Hornung V. Synthesis of an arrayed sgRNA library targeting the human genome. Sci Rep. 2015;5:14987 pubmed publisher
  • western blot; mouse; fig 6a
Londrigan S, Short K, Ma J, Gillespie L, Rockman S, Brooks A, et al. Infection of Mouse Macrophages by Seasonal Influenza Viruses Can Be Restricted at the Level of Virus Entry and at a Late Stage in the Virus Life Cycle. J Virol. 2015;89:12319-29 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Ferdaoussi M, Dai X, Jensen M, Wang R, Peterson B, Huang C, et al. Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells. J Clin Invest. 2015;125:3847-60 pubmed publisher
  • western blot; human; 1:1000; fig 2c
  • western blot; mouse; 1:1000; fig 6d
Ho D, Kim H, Kim J, Sim H, Ahn H, Kim J, et al. Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression. Mol Brain. 2015;8:54 pubmed publisher
  • western blot; human; 1:1000; fig s4
Gebhardt A, Habjan M, Benda C, Meiler A, Haas D, Hein M, et al. mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3. Nat Commun. 2015;6:8192 pubmed publisher
  • western blot; mouse; fig 1
Chen H, Sun Y, Lai L, Wu H, Xiao Y, Ming B, et al. Interleukin-33 is released in spinal cord and suppresses experimental autoimmune encephalomyelitis in mice. Neuroscience. 2015;308:157-68 pubmed publisher
  • western blot; human; fig 3a
Rodríguez C, Reidel S, Bal de Kier Joffé E, Jasnis M, Fiszman G. Autophagy Protects from Trastuzumab-Induced Cytotoxicity in HER2 Overexpressing Breast Tumor Spheroids. PLoS ONE. 2015;10:e0137920 pubmed publisher
  • western blot; human; fig 4
Ray A, Vasudevan S, Sengupta S. 6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death. PLoS ONE. 2015;10:e0137614 pubmed publisher
  • western blot; human; fig 1e
Vennin C, Spruyt N, Dahmani F, Julien S, Bertucci F, Finetti P, et al. H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b. Oncotarget. 2015;6:29209-23 pubmed publisher
  • western blot; mouse; fig 1
Hu M, Wang Z, Teng Y, Jiang Z, Ma X, Hou N, et al. Loss of protein phosphatase 6 in oocytes causes failure of meiosis II exit and impaired female fertility. J Cell Sci. 2015;128:3769-80 pubmed publisher
  • western blot; human; loading ...; fig 4
Weaver A, Cooper T, Rodriguez M, Trummell H, Bonner J, Rosenthal E, et al. DNA double strand break repair defect and sensitivity to poly ADP-ribose polymerase (PARP) inhibition in human papillomavirus 16-positive head and neck squamous cell carcinoma. Oncotarget. 2015;6:26995-7007 pubmed publisher
  • western blot; human; fig 8
Clark D, Tripathi K, Dorsman J, Palle K. FANCJ protein is important for the stability of FANCD2/FANCI proteins and protects them from proteasome and caspase-3 dependent degradation. Oncotarget. 2015;6:28816-32 pubmed publisher
  • western blot; mouse; fig 2
Okoro E, Zhang H, Guo Z, Yang F, Smith C, Yang H. A Subregion of Reelin Suppresses Lipoprotein-Induced Cholesterol Accumulation in Macrophages. PLoS ONE. 2015;10:e0136895 pubmed publisher
  • western blot; mouse; fig 4a
Lee Y, Yun M, Kim H, Jeon B, Park B, Lee B, et al. Exogenous administration of DLK1 ameliorates hepatic steatosis and regulates gluconeogenesis via activation of AMPK. Int J Obes (Lond). 2016;40:356-65 pubmed publisher
  • western blot; mouse; fig 2
Singh V, Alex J, Lakshmi B, Sailasree S, Raj T, Kumar S. Role of mouse Wdr13 in placental growth; a genetic evidence for lifetime body weight determination by placenta during development. Sci Rep. 2015;5:13371 pubmed publisher
  • western blot; rat; 1:1000; fig 2
Lv X, Guo F, Xu X, Chen Z, Sun X, Min D, et al. Abnormal alterations in the Ca²⁺/CaV1.2/calmodulin/caMKII signaling pathway in a tremor rat model and in cultured hippocampal neurons exposed to Mg²⁺-free solution. Mol Med Rep. 2015;12:6663-71 pubmed publisher
  • western blot; human
Badr H, Alsadek D, Mathew M, Li C, Djansugurova L, Yarema K, et al. Nutrient-deprived cancer cells preferentially use sialic acid to maintain cell surface glycosylation. Biomaterials. 2015;70:23-36 pubmed publisher
  • western blot; human; fig 4
Wunsch E, Milkiewicz M, Wasik U, Trottier J, Kempińska Podhorodecka A, Elias E, et al. Expression of hepatic Fibroblast Growth Factor 19 is enhanced in Primary Biliary Cirrhosis and correlates with severity of the disease. Sci Rep. 2015;5:13462 pubmed publisher
  • western blot; rat; 1:25,000; fig 4
Gilda J, Ghosh R, Cheah J, West T, Bodine S, Gomes A. Western Blotting Inaccuracies with Unverified Antibodies: Need for a Western Blotting Minimal Reporting Standard (WBMRS). PLoS ONE. 2015;10:e0135392 pubmed publisher
  • western blot; human; 1 ug/ml; loading ...
Menz C, Parsi M, Adams J, Sideek M, Kopecki Z, Cowin A, et al. LTBP-2 Has a Single High-Affinity Binding Site for FGF-2 and Blocks FGF-2-Induced Cell Proliferation. PLoS ONE. 2015;10:e0135577 pubmed publisher
  • western blot; human; fig 4
Cui H, Li Q, Chen J, Na Q, Liu C. Hepatitis B virus X protein modifies invasion, proliferation and the inflammatory response in an HTR-8/SVneo cell model. Oncol Rep. 2015;34:2090-8 pubmed publisher
  • western blot; human; 1:5000; fig 4
  • western blot; mouse; 1:5000; fig 5
Barger C, Zhang W, Hillman J, Stablewski A, Higgins M, Vanderhyden B, et al. Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression. Oncotarget. 2015;6:27613-27 pubmed publisher
  • western blot; human; fig 1
Ritho J, Arold S, Yeh E. A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy Stress. Cell Rep. 2015;12:734-42 pubmed publisher
  • western blot; rat; 1:300; fig 6
Nishimatsu H, Suzuki E, Saito Y, Niimi A, Nomiya A, Yamada D, et al. Neuromedin B Restores Erectile Function by Protecting the Cavernous Body and the Nitrergic Nerves from Injury in a Diabetic Rat Model. PLoS ONE. 2015;10:e0133874 pubmed publisher
  • western blot; human; fig 1
Woo Park J, Kim K, Kim J, Chae Y, Jeong O, Seo S. RE-IIBP Methylates H3K79 and Induces MEIS1-mediated Apoptosis via H2BK120 Ubiquitination by RNF20. Sci Rep. 2015;5:12485 pubmed publisher
  • western blot; rat
Winsauer P, Filipeanu C, Weed P, Sutton J. Hormonal status and age differentially affect tolerance to the disruptive effects of delta-9-tetrahydrocannabinol (Δ(9)-THC) on learning in female rats. Front Pharmacol. 2015;6:133 pubmed publisher
  • western blot; human; fig 8
Gough K, Maddison B, Shikotra A, Moiseeva E, Yang W, Jarvis S, et al. Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells. Respir Res. 2015;16:86 pubmed publisher
  • western blot; human; 1:1000
Yao X, Wu Y, Zhu M, Qian H, Chen Y. Nitric oxide/cyclic guanosine monophosphate inducers sodium nitroprusside and L-arginine inhibit the proliferation of gastric cancer cells via the activation of type II cyclic guanosine monophosphate-dependent protein kinase. Oncol Lett. 2015;10:479-484 pubmed
  • immunohistochemistry - free floating section; rat
Gorojod R, Alaimo A, Porte Alcon S, Pomilio C, Saravia F, Kotler M. The autophagic- lysosomal pathway determines the fate of glial cells under manganese- induced oxidative stress conditions. Free Radic Biol Med. 2015;87:237-51 pubmed publisher
  • western blot; human
Azzi S, Gallerne C, Romei C, Le Coz V, Gangemi R, Khawam K, et al. Human Renal Normal, Tumoral, and Cancer Stem Cells Express Membrane-Bound Interleukin-15 Isoforms Displaying Different Functions. Neoplasia. 2015;17:509-17 pubmed publisher
  • western blot; mouse
Jung E, Sim Y, Jeong H, Kim S, Yun Y, Song J, et al. Jmjd2C increases MyoD transcriptional activity through inhibiting G9a-dependent MyoD degradation. Biochim Biophys Acta. 2015;1849:1081-94 pubmed publisher
  • western blot; human; fig 3
Wu C, Huang K, Yang T, Li Y, Wen C, Hsu S, et al. The Topoisomerase 1 Inhibitor Austrobailignan-1 Isolated from Koelreuteria henryi Induces a G2/M-Phase Arrest and Cell Death Independently of p53 in Non-Small Cell Lung Cancer Cells. PLoS ONE. 2015;10:e0132052 pubmed publisher
  • western blot; rat; 1:2000
Tan F, Fu W, Cheng N, Meng D, Gu Y. Ligustrazine reduces blood-brain barrier permeability in a rat model of focal cerebral ischemia and reperfusion. Exp Ther Med. 2015;9:1757-1762 pubmed
  • western blot; human
Ben Salem I, Prola A, Boussabbeh M, Guilbert A, Bacha H, Abid Essefi S, et al. Crocin and Quercetin protect HCT116 and HEK293 cells from Zearalenone-induced apoptosis by reducing endoplasmic reticulum stress. Cell Stress Chaperones. 2015;20:927-38 pubmed publisher
  • western blot; human; fig 2
Cho H, Kang J, Lee J, Lee J, Jeon S, Ko J, et al. Direct regulation of E-cadherin by targeted histone methylation of TALE-SET fusion protein in cancer cells. Oncotarget. 2015;6:23837-44 pubmed
  • western blot; human
Madrigal Matute J, Fernandez García C, Blanco Colio L, Burillo E, Fortuño A, Martinez Pinna R, et al. Thioredoxin-1/peroxiredoxin-1 as sensors of oxidative stress mediated by NADPH oxidase activity in atherosclerosis. Free Radic Biol Med. 2015;86:352-61 pubmed publisher
  • western blot; mouse
Choi J, Kim J, Kim T, Park J, Lee J, Kim H, et al. TRH and TRH receptor system in the basolateral amygdala mediate stress-induced depression-like behaviors. Neuropharmacology. 2015;97:346-56 pubmed publisher
  • western blot; mouse; fig 3
Castillo Lluva S, Hontecillas Prieto L, Blanco Gómez A, Del Mar Sáez Freire M, García Cenador B, García Criado J, et al. A new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development. Oncogene. 2015;34:4777-90 pubmed publisher
  • western blot; mouse; fig 1
Wang J, Chen S, Sun C, Chien T, Chern Y. A central role of TRAX in the ATM-mediated DNA repair. Oncogene. 2016;35:1657-70 pubmed publisher
  • western blot; human; 1:5000
Carthy J, Sundqvist A, Heldin A, van Dam H, Kletsas D, Heldin C, et al. Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling Through ERK1/2. J Cell Physiol. 2015;230:3084-92 pubmed publisher
  • western blot; rat; fig 1
  • western blot; mouse; fig 1
Yu H, Park W, Nam K, Song D, Kim H, Baik T, et al. Neuregulin 1 Controls Glutamate Uptake by Up-regulating Excitatory Amino Acid Carrier 1 (EAAC1). J Biol Chem. 2015;290:20233-44 pubmed publisher
  • western blot; human; fig 4
Ma S, Yin N, Qi X, Pfister S, Zhang M, Ma R, et al. Tyrosine dephosphorylation enhances the therapeutic target activity of epidermal growth factor receptor (EGFR) by disrupting its interaction with estrogen receptor (ER). Oncotarget. 2015;6:13320-33 pubmed
  • western blot; mouse
Evonuk K, Baker B, Doyle R, Moseley C, Sestero C, Johnston B, et al. Inhibition of System Xc(-) Transporter Attenuates Autoimmune Inflammatory Demyelination. J Immunol. 2015;195:450-463 pubmed publisher
  • western blot; human
Park S, Choi S, Yoo S, Nah J, Jeong E, Kim H, et al. Pyruvate stimulates mitophagy via PINK1 stabilization. Cell Signal. 2015;27:1824-30 pubmed publisher
  • western blot; human; fig 7a
Kang D, Skalsky R, Cullen B. EBV BART MicroRNAs Target Multiple Pro-apoptotic Cellular Genes to Promote Epithelial Cell Survival. PLoS Pathog. 2015;11:e1004979 pubmed publisher
  • western blot; human; 1:1000; fig 2
Tong T, Kim N, Park T. Topical Application of Oleuropein Induces Anagen Hair Growth in Telogen Mouse Skin. PLoS ONE. 2015;10:e0129578 pubmed publisher
  • western blot; mouse; fig 9a
Xie C, Wei D, Zhao L, Marchetto S, Mei L, Borg J, et al. Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis. J Cell Biol. 2015;209:721-37 pubmed publisher
  • western blot; mouse; fig 3a
Wightman S, Uppal A, Pitroda S, Ganai S, Burnette B, Stack M, et al. Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome. Br J Cancer. 2015;113:327-35 pubmed publisher
  • western blot; mouse; 1:1500; fig 6
Wang L, Liang J, Leung P. The ACE2/Ang-(1-7)/Mas Axis Regulates the Development of Pancreatic Endocrine Cells in Mouse Embryos. PLoS ONE. 2015;10:e0128216 pubmed publisher
  • western blot; human; fig 3
Li T, Lu H, Mukherjee D, Lahiri S, Shen C, Yu L, et al. Identification of epidermal growth factor receptor and its inhibitory microRNA141 as novel targets of Krüppel-like factor 8 in breast cancer. Oncotarget. 2015;6:21428-42 pubmed
  • western blot; mouse; fig 3i
Yang N, Li L, Eguether T, Sundberg J, Pazour G, Chen J. Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis. Development. 2015;142:2194-202 pubmed publisher
  • western blot; human; 1:3000; fig 5
Han Y, Lee J, Lee S. Fucoidan inhibits the migration and proliferation of HT-29 human colon cancer cells via the phosphoinositide-3 kinase/Akt/mechanistic target of rapamycin pathways. Mol Med Rep. 2015;12:3446-3452 pubmed publisher
  • western blot; mouse; fig 1
Liang X, Ding Y, Zhang Y, Chai Y, He J, Chiu S, et al. Activation of NRG1-ERBB4 signaling potentiates mesenchymal stem cell-mediated myocardial repairs following myocardial infarction. Cell Death Dis. 2015;6:e1765 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 1
  • western blot; human; 1:500; fig 1
Zhou Y, Han C, Li D, Yu Z, Li F, Li F, et al. Cyclin-dependent kinase 11(p110) (CDK11(p110)) is crucial for human breast cancer cell proliferation and growth. Sci Rep. 2015;5:10433 pubmed publisher
  • western blot; rat
Shen X, Yang L, Yan S, Zheng H, Liang L, Cai X, et al. Fetuin A promotes lipotoxicity in β cells through the TLR4 signaling pathway and the role of pioglitazone in anti-lipotoxicity. Mol Cell Endocrinol. 2015;412:1-11 pubmed publisher
  • western blot; human; 1:2000; fig 4
Hao W, Yuan X, Yu L, Gao C, Sun X, Wang D, et al. Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways. Sci Rep. 2015;5:10336 pubmed publisher
  • western blot; mouse; fig 5
Tian W, Li W, Chen Y, Yan Z, Huang X, Zhuang H, et al. Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy. FEBS Lett. 2015;589:1847-54 pubmed publisher
  • western blot; mouse; fig 3
Li W, Zhang C, Ren A, Li T, Jin R, Li G, et al. Shikonin Suppresses Skin Carcinogenesis via Inhibiting Cell Proliferation. PLoS ONE. 2015;10:e0126459 pubmed publisher
  • western blot; human
Li Y, Wang W, Xu X, Sun S, Xu X, Qu X. {2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}-acetic Acid Methyl Ester Inhibited Hepatocellular Carcinoma Growth in Bel-7402 Cells and Its Resistant Variants by Activation of NOX4 and SIRT3. Biomed Res Int. 2015;2015:491205 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig  1
  • western blot; human; fig  1
Basu S, Majumder S, Bhowal A, Ghosh A, Naskar S, Nandy S, et al. A study of molecular signals deregulating mismatch repair genes in prostate cancer compared to benign prostatic hyperplasia. PLoS ONE. 2015;10:e0125560 pubmed publisher
  • western blot; human; fig 3
Liu H, Wei Q, Wang J, Huang X, Li C, Zheng Q, et al. DNA Polymerases as targets for gene therapy of hepatocellular carcinoma. BMC Cancer. 2015;15:325 pubmed publisher
  • western blot; mouse; fig 1
Li G, Wang J, Ye J, Zhang Y, Zhang Y. PPARα Protein Expression Was Increased by Four Weeks of Intermittent Hypoxic Training via AMPKα2-Dependent Manner in Mouse Skeletal Muscle. PLoS ONE. 2015;10:e0122593 pubmed publisher
  • western blot; human; fig 4
Tate C, Mc Entire J, Pallini R, Vakana E, Wyss L, Blosser W, et al. A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology. PLoS ONE. 2015;10:e0125697 pubmed publisher
  • western blot; human; 1:300; fig 5
Nishimatsu H, Suzuki E, Saito Y, Niimi A, Nomiya A, Fukuhara H, et al. Senescent Cells Impair Erectile Function through Induction of Endothelial Dysfunction and Nerve Injury in Mice. PLoS ONE. 2015;10:e0124129 pubmed publisher
  • western blot; human; fig 1
Min K, Liggett J, Silva G, Wu W, Wang R, Shen R, et al. NAG-1/GDF15 accumulates in the nucleus and modulates transcriptional regulation of the Smad pathway. Oncogene. 2016;35:377-88 pubmed publisher
  • western blot; mouse; 1:1000
Apostoli A, Roche J, Schneider M, SenGupta S, Di Lena M, Rubino R, et al. Opposing roles for mammary epithelial-specific PPARγ signaling and activation during breast tumour progression. Mol Cancer. 2015;14:85 pubmed publisher
  • western blot; rat; 1:2000
Guo S, Jin Y, Fang Q, You C, Wang X, Hu X, et al. Beneficial effects of hydrogen-rich saline on early burn-wound progression in rats. PLoS ONE. 2015;10:e0124897 pubmed publisher
  • western blot; mouse; fig 6c
Li L, Dong Q, Wang Y, Feng Q, Zhou P, Ou X, et al. Hedgehog signaling is involved in the BMP9-induced osteogenic differentiation of mesenchymal stem cells. Int J Mol Med. 2015;35:1641-50 pubmed publisher
  • western blot; human; fig 7
Sun Y, Zhang T, Wang C, Jin X, Jia C, Yu S, et al. MiRNA-615-5p functions as a tumor suppressor in pancreatic ductal adenocarcinoma by targeting AKT2. PLoS ONE. 2015;10:e0119783 pubmed publisher
  • western blot; human; 1:500; fig 4
Witkiewicz A, McMillan E, Balaji U, Baek G, Lin W, Mansour J, et al. Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets. Nat Commun. 2015;6:6744 pubmed publisher
  • western blot; rat; fig 3
Ali Q, Patel S, Hussain T. Angiotensin AT2 receptor agonist prevents salt-sensitive hypertension in obese Zucker rats. Am J Physiol Renal Physiol. 2015;308:F1379-85 pubmed publisher
  • western blot; fruit fly ; fig 2
Panda D, Gold B, Tartell M, Rausch K, Casas Tinto S, Cherry S. The transcription factor FoxK participates with Nup98 to regulate antiviral gene expression. MBio. 2015;6: pubmed publisher
  • western blot; rat; 1:1000; fig 1
Zhao J, Song Q, Wang L, Dong X, Yang X, Bai X, et al. Detrusor myocyte autophagy protects the bladder function via inhibiting the inflammation in cyclophosphamide-induced cystitis in rats. PLoS ONE. 2015;10:e0122597 pubmed publisher
  • western blot; human; fig 1
  • western blot; rat; fig 4
Cerqueira O, Truesdell P, Baldassarre T, Vilella Arias S, Watt K, Meens J, et al. CIP4 promotes metastasis in triple-negative breast cancer and is associated with poor patient prognosis. Oncotarget. 2015;6:9397-408 pubmed
  • western blot; human; fig 6
Li S, Wu X, Dong C, Xie X, Wu J, Zhang X. The differential expression of OCT4 isoforms in cervical carcinoma. PLoS ONE. 2015;10:e0118033 pubmed publisher
  • western blot; human; fig 3
Zhang Z, Fang Y, Wang Q, Sun Y, Xiong C, Cao L, et al. Tumor necrosis factor-like weak inducer of apoptosis regulates particle-induced inflammatory osteolysis via the p38 mitogen-activated protein kinase signaling pathway. Mol Med Rep. 2015;12:1499-505 pubmed publisher
  • western blot; human; 1:2500; fig 2
Hoekstra E, Kodach L, Das A, Ruela de Sousa R, Ferreira C, Hardwick J, et al. Low molecular weight protein tyrosine phosphatase (LMWPTP) upregulation mediates malignant potential in colorectal cancer. Oncotarget. 2015;6:8300-12 pubmed
  • western blot; guinea pig; fig 5
Ivan V, van der Sluijs P. Methods for analysis of AP-3/Rabin4' in regulation of lysosome distribution. Methods Mol Biol. 2015;1298:245-58 pubmed publisher
  • western blot; chicken; 1:1000
Padmanabhan R, Taneyhill L. Cadherin-6B undergoes macropinocytosis and clathrin-mediated endocytosis during cranial neural crest cell EMT. J Cell Sci. 2015;128:1773-86 pubmed publisher
  • western blot; pigs
Qu X, Pröll M, Neuhoff C, Zhang R, Cinar M, Hossain M, et al. Sulforaphane epigenetically regulates innate immune responses of porcine monocyte-derived dendritic cells induced with lipopolysaccharide. PLoS ONE. 2015;10:e0121574 pubmed publisher
  • western blot; rat; 1:1000
Patki G, Salvi A, Liu H, Atrooz F, Alkadhi I, Kelly M, et al. Tempol treatment reduces anxiety-like behaviors induced by multiple anxiogenic drugs in rats. PLoS ONE. 2015;10:e0117498 pubmed publisher
  • western blot; human; 1:500
Kitsiouli E, Antoniou G, Gotzou H, Karagiannopoulos M, Basagiannis D, Christoforidis S, et al. Effect of azithromycin on the LPS-induced production and secretion of phospholipase A2 in lung cells. Biochim Biophys Acta. 2015;1852:1288-97 pubmed publisher
  • western blot; rat; 1:500; fig 3
Wu J, Liu B, Tong W, Zhang A, Li F, Lin J, et al. Opioid receptors and associated regulator of G protein signaling are involved in the cathartic colon of rats. Exp Ther Med. 2015;9:1229-1234 pubmed
  • western blot; mouse; 1:1000
Kesherwani V, Nandi S, Sharawat S, Shahshahan H, Mishra P. Hydrogen sulfide mitigates homocysteine-mediated pathological remodeling by inducing miR-133a in cardiomyocytes. Mol Cell Biochem. 2015;404:241-50 pubmed publisher
  • western blot; human; fig 1f
Rappa G, Green T, Karbanová J, Corbeil D, Lorico A. Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells. Oncotarget. 2015;6:7970-91 pubmed
  • western blot; human; fig 1
Katagiri N, Kuroda T, Kishimoto H, Hayashi Y, Kumazawa T, Kimura K. The nucleolar protein nucleophosmin is essential for autophagy induced by inhibiting Pol I transcription. Sci Rep. 2015;5:8903 pubmed publisher
  • western blot; mouse; 1:10,000; fig 5
Chen W, Wu J, Li L, Zhang Z, Ren J, Liang Y, et al. Ppm1b negatively regulates necroptosis through dephosphorylating Rip3. Nat Cell Biol. 2015;17:434-44 pubmed publisher
  • immunocytochemistry; human
Jeong H, Jung E, Sim Y, Kim S, Jang J, Hong K, et al. Fbxo25 controls Tbx5 and Nkx2-5 transcriptional activity to regulate cardiomyocyte development. Biochim Biophys Acta. 2015;1849:709-21 pubmed publisher
  • western blot; human; fig s3
Uppal A, Wightman S, Mallon S, Oshima G, Pitroda S, Zhang Q, et al. 14q32-encoded microRNAs mediate an oligometastatic phenotype. Oncotarget. 2015;6:3540-52 pubmed
  • western blot; mouse; 1:2500; fig 4
Suman S, Kallakury B, Fornace A, Datta K. Protracted upregulation of leptin and IGF1 is associated with activation of PI3K/Akt and JAK2 pathway in mouse intestine after ionizing radiation exposure. Int J Biol Sci. 2015;11:274-83 pubmed publisher
  • western blot; human; fig 2
Kobayashi K, Sakurai K, Hiramatsu H, Inada K, Shiogama K, Nakamura S, et al. The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines. Sci Rep. 2015;5:8428 pubmed publisher
  • western blot; human; fig 2
Jeong H, Gil N, Lee H, Cho S, Kim K, Chun K, et al. Timely Degradation of Wip1 Phosphatase by APC/C Activator Protein Cdh1 is Necessary for Normal Mitotic Progression. J Cell Biochem. 2015;116:1602-12 pubmed publisher
  • western blot; human
Moreno Navarrete J, Moreno M, Vidal M, Ortega F, Serrano M, Xifra G, et al. Deleted in breast cancer 1 plays a functional role in adipocyte differentiation. Am J Physiol Endocrinol Metab. 2015;308:E554-61 pubmed publisher
  • western blot; human; 1:10,000; fig 5
Xue J, Chen Y, Wu Y, Wang Z, Zhou A, Zhang S, et al. Tumour suppressor TRIM33 targets nuclear β-catenin degradation. Nat Commun. 2015;6:6156 pubmed publisher
  • western blot; human; fig 1
Guan J, Zhang X, Sun W, Qi L, Wu J, Qin Z. DRAM1 regulates apoptosis through increasing protein levels and lysosomal localization of BAX. Cell Death Dis. 2015;6:e1624 pubmed publisher
  • western blot; human
Zou J, Li W, Misra A, Yue F, Song K, Chen Q, et al. The viral restriction factor tetherin prevents leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) from association with beclin 1 and B-cell CLL/lymphoma 2 (Bcl-2) and enhances autophagy and mitophagy. J Biol Chem. 2015;290:7269-79 pubmed publisher
  • western blot; mouse; fig 2
HERRERA V, Pasion K, Moran A, Zaninello R, Ortu M, Fresu G, et al. A functional 12T-insertion polymorphism in the ATP1A1 promoter confers decreased susceptibility to hypertension in a male Sardinian population. PLoS ONE. 2015;10:e0116724 pubmed publisher
  • western blot; human
Kaihola H, Olivier J, Poromaa I, Akerud H. The effect of antenatal depression and selective serotonin reuptake inhibitor treatment on nerve growth factor signaling in human placenta. PLoS ONE. 2015;10:e0116459 pubmed publisher
  • western blot; human; fig 5b
Kang O, Kim S, Mun S, Seo Y, Hwang H, Lee Y, et al. Puerarin ameliorates hepatic steatosis by activating the PPARα and AMPK signaling pathways in hepatocytes. Int J Mol Med. 2015;35:803-9 pubmed publisher
  • western blot; human; 1:2000; fig 1
Yu C, Yang S, Fang X, Jiang J, Sun C, Huang T. Hypoxia disrupts the expression levels of circadian rhythm genes in hepatocellular carcinoma. Mol Med Rep. 2015;11:4002-8 pubmed publisher
  • western blot; mouse; fig 6
Kim K, Kim N, Kim S, Kim I, Kim K, Lee G. Cyclo(Phe-Pro) produced by the human pathogen Vibrio vulnificus inhibits host innate immune responses through the NF-κB pathway. Infect Immun. 2015;83:1150-61 pubmed publisher
  • western blot; human; fig 3
Kim E, Lee J, Jung Y, Park J, Park M, Lee J, et al. Involvement of corin downregulation in ionizing radiation-induced senescence of myocardial cells. Int J Mol Med. 2015;35:731-8 pubmed publisher
  • western blot; mouse; 1:2000
Ohno M, Kanayama T, Moore R, Ray M, Negishi M. The roles of co-chaperone CCRP/DNAJC7 in Cyp2b10 gene activation and steatosis development in mouse livers. PLoS ONE. 2014;9:e115663 pubmed publisher
  • western blot; mouse
Lin Y, Liu P, Adhikari N, Hall J, Wei L. RIP140 contributes to foam cell formation and atherosclerosis by regulating cholesterol homeostasis in macrophages. J Mol Cell Cardiol. 2015;79:287-94 pubmed publisher
  • western blot; human; 1:2000
Naganuma K, Hatta M, Ikebe T, Yamazaki J. Epigenetic alterations of the keratin 13 gene in oral squamous cell carcinoma. BMC Cancer. 2014;14:988 pubmed publisher
  • western blot; mouse
Hamanoue M, Ikeda Y, Ogata T, Takamatsu K. Predominant expression of N-acetylglucosaminyltransferase V (GnT-V) in neural stem/progenitor cells. Stem Cell Res. 2015;14:68-78 pubmed publisher
  • western blot; human
Li W, Ouyang Z, Zhang Q, Wang L, Shen Y, Gu Y, et al. SBF-1 exerts strong anticervical cancer effect through inducing endoplasmic reticulum stress-associated cell death via targeting sarco/endoplasmic reticulum Ca(2+)-ATPase 2. Cell Death Dis. 2014;5:e1581 pubmed publisher
  • western blot; human
Hoffmann F, Kuhn P, Laurent S, Hauck S, Berer K, Wendlinger S, et al. The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity. J Immunol. 2015;194:542-52 pubmed publisher
  • western blot; carp; 1:3000
Vaccaro R, Toni M, Casini A, Vivacqua G, Yu S, D Este L, et al. Localization of α-synuclein in teleost central nervous system: immunohistochemical and Western blot evidence by 3D5 monoclonal antibody in the common carp, Cyprinus carpio. J Comp Neurol. 2015;523:1095-124 pubmed publisher
  • western blot; human
Kabbaj F, Lu S, Faouzi M, Meddah B, Proksch P, Cherrah Y, et al. Bioactive metabolites from Chaetomium aureum: structure elucidation and inhibition of the Hsp90 machine chaperoning activity. Bioorg Med Chem. 2015;23:126-31 pubmed publisher
  • western blot; human; 1:2000
Wilson L, McKeown L, Tumova S, Li J, Beech D. Expression of a long variant of CRACR2A that belongs to the Rab GTPase protein family in endothelial cells. Biochem Biophys Res Commun. 2015;456:398-402 pubmed publisher
  • western blot; rhesus macaque; fig s1
O Connell K, Guo W, Serra C, Beck M, Wachtman L, Hoggatt A, et al. The effects of an ActRIIb receptor Fc fusion protein ligand trap in juvenile simian immunodeficiency virus-infected rhesus macaques. FASEB J. 2015;29:1165-75 pubmed publisher
  • western blot; human; fig 2
Wang H, Zhang L, Zhang S, Li Y. Inhibition of vascular endothelial growth factor by small interfering RNA upregulates differentiation, maturation and function of dendritic cells. Exp Ther Med. 2015;9:120-124 pubmed
  • western blot; mouse
Mou W, Xu Y, Ye Y, Chen S, Li X, Gong K, et al. Expression of Sox2 in breast cancer cells promotes the recruitment of M2 macrophages to tumor microenvironment. Cancer Lett. 2015;358:115-23 pubmed publisher
  • western blot; human; 1:1000; fig 6
Lu W, Han L, Su L, Zhao J, Zhang Y, Zhang S, et al. A 3'UTR-associated RNA, FLJ11812 maintains stemness of human embryonic stem cells by targeting miR-4459. Stem Cells Dev. 2015;24:1133-40 pubmed publisher
  • western blot; mouse
Beutner G, Eliseev R, Porter G. Initiation of electron transport chain activity in the embryonic heart coincides with the activation of mitochondrial complex 1 and the formation of supercomplexes. PLoS ONE. 2014;9:e113330 pubmed publisher
  • western blot; rat; 1:1000
Choi T, Jung S, Nah J, Ko H, Jo S, Chung G, et al. Low levels of methyl β-cyclodextrin disrupt GluA1-dependent synaptic potentiation but not synaptic depression. J Neurochem. 2015;132:276-85 pubmed publisher
  • western blot; human; 1:500
Isobe T, Hisamori S, Hogan D, Zabala M, Hendrickson D, Dalerba P, et al. miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway. elife. 2014;3: pubmed publisher
  • western blot; human; 1:2000
  • western blot; mouse; 1:2000
Siggs O, Grieve A, Xu H, Bambrough P, Christova Y, Freeman M. Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice. Biol Open. 2014;3:1151-7 pubmed publisher
  • western blot; human; fig 4
Wang C, Zhang W, Fu M, Yang A, Huang H, Xie J. Establishment of human pancreatic cancer gemcitabine‑resistant cell line with ribonucleotide reductase overexpression. Oncol Rep. 2015;33:383-90 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5a
Gao L, Fang Y, Zhang T, Ge B, Xu B, Huang J, et al. GSTP1 arrests bladder cancer T24 cells in G0/G1 phase and up-regulates p21 expression. Int J Clin Exp Med. 2014;7:2984-91 pubmed
  • western blot; human
Soncini D, Caffa I, Zoppoli G, Cea M, Cagnetta A, Passalacqua M, et al. Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. J Biol Chem. 2014;289:34189-204 pubmed publisher
  • western blot; human; fig 3
O Loghlen A, Martin N, Krusche B, Pemberton H, Alonso M, Chandler H, et al. The nuclear receptor NR2E1/TLX controls senescence. Oncogene. 2015;34:4069-4077 pubmed publisher
  • western blot; mouse
Xu H, Zhou Y, Coughlan K, Ding Y, Wang S, Wu Y, et al. AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts. Biochim Biophys Acta. 2015;1853:65-73 pubmed publisher
  • western blot; mouse; fig 7
Martin G, Atshaves B, Landrock K, Landrock D, Storey S, Howles P, et al. Ablating L-FABP in SCP-2/SCP-x null mice impairs bile acid metabolism and biliary HDL-cholesterol secretion. Am J Physiol Gastrointest Liver Physiol. 2014;307:G1130-43 pubmed publisher
  • western blot; human; 1:1000; fig 5
Zheng R, Hu W, Sui C, Ma N, Jiang Y. Effects of doxorubicin and gemcitabine on the induction of apoptosis in breast cancer cells. Oncol Rep. 2014;32:2719-25 pubmed publisher
  • western blot; mouse
Tassi I, Claudio E, Wang H, Tang W, Ha H, Saret S, et al. The NF-κB regulator Bcl-3 governs dendritic cell antigen presentation functions in adaptive immunity. J Immunol. 2014;193:4303-11 pubmed publisher
  • western blot; mouse; 1:30000
Kurokawa K, Mizuno K, Ohkuma S. Sensitization of ethanol-induced place preference as a result of up-regulation of type 1 inositol 1,4,5-trisphosphate receptors in mouse nucleus accumbens. J Neurochem. 2014;131:836-47 pubmed publisher
  • western blot; human
Sonzogni S, Ogara M, Castillo D, Sirkin P, Radicella J, Cánepa E. Nuclear translocation of p19INK4d in response to oxidative DNA damage promotes chromatin relaxation. Mol Cell Biochem. 2015;398:63-72 pubmed publisher
  • western blot; kangaroo rats; 1:2000; fig 1
Pilchova I, Klacanova K, Chomova M, Tatarkova Z, Dobrota D, Racay P. Possible contribution of proteins of Bcl-2 family in neuronal death following transient global brain ischemia. Cell Mol Neurobiol. 2015;35:23-31 pubmed publisher
  • western blot; human
Cho S, Park J, Kang Y. AGO2 and SETDB1 cooperate in promoter-targeted transcriptional silencing of the androgen receptor gene. Nucleic Acids Res. 2014;42:13545-56 pubmed publisher
  • western blot; mouse
Yang S, Deng P, Zhu Z, Zhu J, Wang G, Zhang L, et al. Adenosine deaminase acting on RNA 1 limits RIG-I RNA detection and suppresses IFN production responding to viral and endogenous RNAs. J Immunol. 2014;193:3436-45 pubmed publisher
  • western blot; human
Tomicic M, Aasland D, Naumann S, Meise R, Barckhausen C, Kaina B, et al. Translesion polymerase ? is upregulated by cancer therapeutics and confers anticancer drug resistance. Cancer Res. 2014;74:5585-96 pubmed publisher
  • western blot; mouse; 1:1000
Jousse C, Muranishi Y, Parry L, Montaurier C, Even P, Launay J, et al. Perinatal protein malnutrition affects mitochondrial function in adult and results in a resistance to high fat diet-induced obesity. PLoS ONE. 2014;9:e104896 pubmed publisher
  • western blot; human; 1:10,000; fig 3
Van Brocklyn J, Wojton J, Meisen W, Kellough D, Ecsedy J, Kaur B, et al. Aurora-A inhibition offers a novel therapy effective against intracranial glioblastoma. Cancer Res. 2014;74:5364-70 pubmed publisher
  • western blot; mouse; fig 2
Xiao Z, Huang J, Cao L, Liang Y, Han X, Quarles L. Osteocyte-specific deletion of Fgfr1 suppresses FGF23. PLoS ONE. 2014;9:e104154 pubmed publisher
  • western blot; rat; 1:1000
Li K, Zhao G, Li L, Wu G, Cui S. Epigenetic upregulation of Cdk5 in the dorsal horn contributes to neuropathic pain in rats. Neuroreport. 2014;25:1116-21 pubmed publisher
  • western blot; human
Pohl M, Edinger T, Stertz S. Prolidase is required for early trafficking events during influenza A virus entry. J Virol. 2014;88:11271-83 pubmed publisher
  • western blot; dogs
Taub M, Parker R, Mathivanan P, Ariff M, Rudra T. Antagonism of the prostaglandin E2 EP1 receptor in MDCK cells increases growth through activation of Akt and the epidermal growth factor receptor. Am J Physiol Renal Physiol. 2014;307:F539-50 pubmed publisher
  • western blot; human
Li C, Chen J, Lu B, Shi Z, Wang H, Zhang B, et al. Molecular switch role of Akt in Polygonatum odoratum lectin-induced apoptosis and autophagy in human non-small cell lung cancer A549 cells. PLoS ONE. 2014;9:e101526 pubmed publisher
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Gou W, Zhao Y, Lu H, Yang X, Xiu Y, Zhao S, et al. The role of RhoC in epithelial-to-mesenchymal transition of ovarian carcinoma cells. BMC Cancer. 2014;14:477 pubmed publisher
  • western blot; human
Chang P, Hung C, Wang S, Tsai P, Shih Y, Chen L, et al. Identification and characterization of two novel spliced genes located in the orf47-orf46-orf45 gene locus of Kaposi's sarcoma-associated herpesvirus. J Virol. 2014;88:10092-109 pubmed publisher
  • western blot; mouse
Su Z, Yin J, Wang T, Sun Y, Ni P, Ma R, et al. Up-regulated HMGB1 in EAM directly led to collagen deposition by a PKC?/Erk1/2-dependent pathway: cardiac fibroblast/myofibroblast might be another source of HMGB1. J Cell Mol Med. 2014;18:1740-51 pubmed publisher
  • western blot; bovine
Zielniok K, Motyl T, Gajewska M. Functional interactions between 17 ? -estradiol and progesterone regulate autophagy during acini formation by bovine mammary epithelial cells in 3D cultures. Biomed Res Int. 2014;2014:382653 pubmed publisher
  • western blot; human; 1:1000; fig 5
Tu K, Yang W, Li C, Zheng X, Lu Z, Guo C, et al. Fbxw7 is an independent prognostic marker and induces apoptosis and growth arrest by regulating YAP abundance in hepatocellular carcinoma. Mol Cancer. 2014;13:110 pubmed publisher
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Hsieh F, Chen N, Yao Y, Wang S, Chen J, Lai C, et al. The transcriptional repression activity of STAF65γ is facilitated by promoter tethering and nuclear import of class IIa histone deacetylases. Biochim Biophys Acta. 2014;1839:579-91 pubmed publisher
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Chu D, Malinowska E, Gawronska Kozak B, Kozak L. Expression of adipocyte biomarkers in a primary cell culture models reflects preweaning adipobiology. J Biol Chem. 2014;289:18478-88 pubmed publisher
  • western blot; domestic sheep; 1:1000
Dengler F, Rackwitz R, Benesch F, Pfannkuche H, Gabel G. Both butyrate incubation and hypoxia upregulate genes involved in the ruminal transport of SCFA and their metabolites. J Anim Physiol Anim Nutr (Berl). 2015;99:379-90 pubmed publisher
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Qi Y, Wang M, Liu R, Wei H, Chao W, Zhang T, et al. Downregulation of 14-3-3σ correlates with multistage carcinogenesis and poor prognosis of esophageal squamous cell carcinoma. PLoS ONE. 2014;9:e95386 pubmed publisher
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Chen R, Zhang F, Song L, Shu Y, Lin Y, Dong L, et al. Transcriptome profiling reveals that the SM22?-regulated molecular pathways contribute to vascular pathology. J Mol Cell Cardiol. 2014;72:263-72 pubmed publisher
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Kumar V, Palermo R, Talora C, Campese A, Checquolo S, Bellavia D, et al. Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia. Leukemia. 2014;28:2324-35 pubmed publisher
  • western blot; human
Han L, Masani S, Hsieh C, Yu K. DNA ligase I is not essential for mammalian cell viability. Cell Rep. 2014;7:316-320 pubmed publisher
  • western blot; human
Zou J, Yue F, Li W, Song K, Jiang X, Yi J, et al. Autophagy inhibitor LRPPRC suppresses mitophagy through interaction with mitophagy initiator Parkin. PLoS ONE. 2014;9:e94903 pubmed publisher
  • western blot; mouse
Wu Z, Zhu Y, Cao X, Sun S, Zhao B. Mitochondrial toxic effects of A? through mitofusins in the early pathogenesis of Alzheimer's disease. Mol Neurobiol. 2014;50:986-96 pubmed publisher
  • western blot; human
Rozelle D, Filone C, Kedersha N, Connor J. Activation of stress response pathways promotes formation of antiviral granules and restricts virus replication. Mol Cell Biol. 2014;34:2003-16 pubmed publisher
  • western blot; mouse; 1:500
Etem E, Bal R, Akağaç A, Kuloglu T, Tuzcu M, Andrievsky G, et al. The effects of hydrated C(60) fullerene on gene expression profile of TRPM2 and TRPM7 in hyperhomocysteinemic mice. J Recept Signal Transduct Res. 2014;34:317-24 pubmed publisher
  • western blot; rat; 1:10000
Alaimo A, Gorojod R, Beauquis J, Muñoz M, Saravia F, Kotler M. Deregulation of mitochondria-shaping proteins Opa-1 and Drp-1 in manganese-induced apoptosis. PLoS ONE. 2014;9:e91848 pubmed publisher
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Mackeh R, Lorin S, Ratier A, Mejdoubi Charef N, Baillet A, Bruneel A, et al. Reactive oxygen species, AMP-activated protein kinase, and the transcription cofactor p300 regulate ?-tubulin acetyltransferase-1 (?TAT-1/MEC-17)-dependent microtubule hyperacetylation during cell stress. J Biol Chem. 2014;289:11816-28 pubmed publisher
  • western blot; human; fig 4
Li W, Zhang X, Zhuang H, Chen H, Chen Y, Tian W, et al. MicroRNA-137 is a novel hypoxia-responsive microRNA that inhibits mitophagy via regulation of two mitophagy receptors FUNDC1 and NIX. J Biol Chem. 2014;289:10691-701 pubmed publisher
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Tavukçu H, Sener T, Tinay I, Akbal C, Ersahin M, Cevik O, et al. Melatonin and tadalafil treatment improves erectile dysfunction after spinal cord injury in rats. Clin Exp Pharmacol Physiol. 2014;41:309-16 pubmed publisher
  • western blot; human; 1:1000; fig 2
Chen D, Mao M, Bellussi L, Passali D, Chen L. Increase of high mobility group box chromosomal protein 1 in eosinophilic chronic rhinosinusitis with nasal polyps. Int Forum Allergy Rhinol. 2014;4:453-62 pubmed publisher
  • immunoprecipitation; human
  • immunocytochemistry; human
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Chen M, Zhang Y, Yu V, Chong Y, Yoshioka T, Ge R. Isthmin targets cell-surface GRP78 and triggers apoptosis via induction of mitochondrial dysfunction. Cell Death Differ. 2014;21:797-810 pubmed publisher
  • western blot; human; fig 3
Chen Y, Wang Z, Zhou L. Interleukin 8 inhibition enhanced cholesterol efflux in acetylated low-density lipoprotein-stimulated THP-1 macrophages. J Investig Med. 2014;62:615-20 pubmed publisher
  • western blot; human; fig 6
Chung Y, Pan C, Liou W, Sheu M, Lin W, Chen T, et al. NSC746364, a G-quadruplex-stabilizing agent, suppresses cell growth of A549 human lung cancer cells through activation of the ATR/Chk1-dependent pathway. J Pharmacol Sci. 2014;124:7-17 pubmed
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Kim S, Park E, Joo H, Shen Y, Hong S, Kim C, et al. RRM1 maintains centrosomal integrity via CHK1 and CDK1 signaling during replication stress. Cancer Lett. 2014;346:249-56 pubmed publisher
  • western blot; mouse; fig 7
Karaca G, Swiderska Syn M, Xie G, Syn W, Krüger L, Machado M, et al. TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice. PLoS ONE. 2014;9:e83987 pubmed publisher
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Wang L, Wang J, Wang Y, Fu Q, Lei Y, Nie Z, et al. Protective effect of exogenous matrix metalloproteinase-9 on chronic renal failure. Exp Ther Med. 2014;7:329-334 pubmed
  • immunoprecipitation; human
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Han J, Hou W, Goldstein L, Stolz D, Watkins S, Rabinowich H. A Complex between Atg7 and Caspase-9: A NOVEL MECHANISM OF CROSS-REGULATION BETWEEN AUTOPHAGY AND APOPTOSIS. J Biol Chem. 2014;289:6485-97 pubmed publisher
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Du Y, Teng X, Wang N, Zhang X, Chen J, Ding P, et al. NF-?B and enhancer-binding CREB protein scaffolded by CREB-binding protein (CBP)/p300 proteins regulate CD59 protein expression to protect cells from complement attack. J Biol Chem. 2014;289:2711-24 pubmed publisher
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Wu K, Chen K, Wang C, Jiao X, Wang L, Zhou J, et al. Cell fate factor DACH1 represses YB-1-mediated oncogenic transcription and translation. Cancer Res. 2014;74:829-39 pubmed publisher
  • western blot; mouse; 1:8000; fig 2
Abdelalim E, Tooyama I. Knockdown of p53 suppresses Nanog expression in embryonic stem cells. Biochem Biophys Res Commun. 2014;443:652-7 pubmed publisher
  • western blot; fission yeast
Brookheart R, Lee C, Espenshade P. Casein kinase 1 regulates sterol regulatory element-binding protein (SREBP) to control sterol homeostasis. J Biol Chem. 2014;289:2725-35 pubmed publisher
  • western blot; mouse; 1:50
Okumu L, Braden T, Vail K, Simon L, GOYAL H. Low androgen induced penile maldevelopment involves altered gene expression of biomarkers of smooth muscle differentiation and a key enzyme regulating cavernous smooth muscle cell tone. J Urol. 2014;192:267-73 pubmed publisher
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Gujar S, Clements D, Dielschneider R, Helson E, Marcato P, Lee P. Gemcitabine enhances the efficacy of reovirus-based oncotherapy through anti-tumour immunological mechanisms. Br J Cancer. 2014;110:83-93 pubmed publisher
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Prentoe J, Serre S, Ramírez S, Nicosia A, Gottwein J, Bukh J. Hypervariable region 1 deletion and required adaptive envelope mutations confer decreased dependency on scavenger receptor class B type I and low-density lipoprotein receptor for hepatitis C virus. J Virol. 2014;88:1725-39 pubmed publisher
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Brandt J, Silveira L, Grassi T, Anselmo Franci J, Fávaro W, Felisbino S, et al. Indole-3-carbinol attenuates the deleterious gestational effects of bisphenol A exposure on the prostate gland of male F1 rats. Reprod Toxicol. 2014;43:56-66 pubmed publisher
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Schiffmacher A, Padmanabhan R, Jhingory S, Taneyhill L. Cadherin-6B is proteolytically processed during epithelial-to-mesenchymal transitions of the cranial neural crest. Mol Biol Cell. 2014;25:41-54 pubmed publisher
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Moreira E, de Oliveira J, Engel D, Walz R, de Bem A, Farina M, et al. Hypercholesterolemia induces short-term spatial memory impairments in mice: up-regulation of acetylcholinesterase activity as an early and causal event?. J Neural Transm (Vienna). 2014;121:415-26 pubmed publisher
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Bondarenko A, Jean Quartier C, Parichatikanond W, Alam M, Waldeck Weiermair M, Malli R, et al. Mitochondrial Ca(2+) uniporter (MCU)-dependent and MCU-independent Ca(2+) channels coexist in the inner mitochondrial membrane. Pflugers Arch. 2014;466:1411-20 pubmed publisher
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Feng N, Han Q, Li J, Wang S, Li H, Yao X, et al. Generation of highly purified neural stem cells from human adipose-derived mesenchymal stem cells by Sox1 activation. Stem Cells Dev. 2014;23:515-29 pubmed publisher
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Park E, Na H, Song Y, Shin S, Kim Y, Chung J. Activation of NLRP3 and AIM2 inflammasomes by Porphyromonas gingivalis infection. Infect Immun. 2014;82:112-23 pubmed publisher
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Lee J, Park J, Kwon O, Kim H, Fornace A, Cha H. Off-target response of a Wip1 chemical inhibitor in skin keratinocytes. J Dermatol Sci. 2014;73:125-34 pubmed publisher
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Hashizume C, Moyori A, Kobayashi A, Yamakoshi N, Endo A, Wong R. Nucleoporin Nup62 maintains centrosome homeostasis. Cell Cycle. 2013;12:3804-16 pubmed publisher
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Li T, Lu H, Shen C, Lahiri S, Wason M, Mukherjee D, et al. Identification of epithelial stromal interaction 1 as a novel effector downstream of Krüppel-like factor 8 in breast cancer invasion and metastasis. Oncogene. 2014;33:4746-55 pubmed publisher
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Tan M, Yu J, Jiang T, Zhu X, Guan H, Tan L. IL12/23 p40 inhibition ameliorates Alzheimer's disease-associated neuropathology and spatial memory in SAMP8 mice. J Alzheimers Dis. 2014;38:633-46 pubmed publisher
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Iordanova B, Hitchens T, Robison C, Ahrens E. Engineered mitochondrial ferritin as a magnetic resonance imaging reporter in mouse olfactory epithelium. PLoS ONE. 2013;8:e72720 pubmed publisher
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Singh B, Sinha R, Zhou J, Xie S, You S, Gauthier K, et al. FoxO1 deacetylation regulates thyroid hormone-induced transcription of key hepatic gluconeogenic genes. J Biol Chem. 2013;288:30365-72 pubmed publisher
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Chen Z, Chen J, Gu Y, Hu C, Li J, Lin S, et al. Aberrantly activated AREG-EGFR signaling is required for the growth and survival of CRTC1-MAML2 fusion-positive mucoepidermoid carcinoma cells. Oncogene. 2014;33:3869-77 pubmed publisher
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Yoshida G, Saya H, Zouboulis C. Three-dimensional culture of sebaceous gland cells revealing the role of prostaglandin E2-induced activation of canonical Wnt signaling. Biochem Biophys Res Commun. 2013;438:640-6 pubmed publisher
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Apostoli A, Skelhorne Gross G, Rubino R, Peterson N, Di Lena M, Schneider M, et al. Loss of PPAR? expression in mammary secretory epithelial cells creates a pro-breast tumorigenic environment. Int J Cancer. 2014;134:1055-66 pubmed publisher
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Hou Z, Han Q, Zhang C, Tian Z, Zhang J. miR146a impairs the IFN-induced anti-HBV immune response by downregulating STAT1 in hepatocytes. Liver Int. 2014;34:58-68 pubmed publisher
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Hafko R, Villapol S, Nostramo R, Symes A, Sabban E, Inagami T, et al. Commercially available angiotensin II At? receptor antibodies are nonspecific. PLoS ONE. 2013;8:e69234 pubmed publisher
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Brouxhon S, Kyrkanides S, Teng X, O Banion M, Clarke R, Byers S, et al. Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers. Mol Carcinog. 2014;53:893-906 pubmed publisher
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Kuttner V, Mack C, Rigbolt K, Kern J, Schilling O, Busch H, et al. Global remodelling of cellular microenvironment due to loss of collagen VII. Mol Syst Biol. 2013;9:657 pubmed publisher
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Choi K, Kang B, Kim H, Lee S, Bae S, Kweon O, et al. Low-level laser therapy promotes the osteogenic potential of adipose-derived mesenchymal stem cells seeded on an acellular dermal matrix. J Biomed Mater Res B Appl Biomater. 2013;101:919-28 pubmed publisher
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Martin N, Popov N, Aguilo F, O Loghlen A, Raguz S, Snijders A, et al. Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK?a regulation. EMBO J. 2013;32:982-95 pubmed publisher
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Kim H, Woo H, Ryu J, Bok J, Kim J, Choi S, et al. Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development. PLoS ONE. 2013;8:e55609 pubmed publisher
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Zhang L, Dasuri K, Fernandez Kim S, Bruce Keller A, Freeman L, Pepping J, et al. Prolonged diet induced obesity has minimal effects towards brain pathology in mouse model of cerebral amyloid angiopathy: implications for studying obesity-brain interactions in mice. Biochim Biophys Acta. 2013;1832:1456-62 pubmed publisher
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Liu T, Sun B, Zhao X, Gu Q, Dong X, Yao Z, et al. HER2/neu expression correlates with vasculogenic mimicry in invasive breast carcinoma. J Cell Mol Med. 2013;17:116-22 pubmed publisher
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Prasad R, Atul -, Soni A, Puri S, Sijwali P. Expression, characterization, and cellular localization of knowpains, papain-like cysteine proteases of the Plasmodium knowlesi malaria parasite. PLoS ONE. 2012;7:e51619 pubmed publisher
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Günther S, Fietz D, Weider K, Bergmann M, Brehm R. Effects of a murine germ cell-specific knockout of Connexin 43 on Connexin expression in testis and fertility. Transgenic Res. 2013;22:631-41 pubmed publisher
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Vazquez Martin A, Sauri Nadal T, Menendez O, Oliveras Ferraros C, Cufí S, Corominas Faja B, et al. Ser2481-autophosphorylated mTOR colocalizes with chromosomal passenger proteins during mammalian cell cytokinesis. Cell Cycle. 2012;11:4211-21 pubmed publisher
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Dinh P, Beura L, Das P, Panda D, Das A, Pattnaik A. Induction of stress granule-like structures in vesicular stomatitis virus-infected cells. J Virol. 2013;87:372-83 pubmed publisher
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Kocer S, Wang H, Malbon C. "Shaping" of cell signaling via AKAP-tethered PDE4D: Probing with AKAR2-AKAP5 biosensor. J Mol Signal. 2012;7:4 pubmed publisher
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product information
Product Name :
beta-Actin (C4) Antibody
Gene Name :
ACTB
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-47778
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
beta-Actin
reactive species  :
m, r, h, avian, bovine, canine, porcine, rabbit, Dictyostelium discoideum, Physarum polycephalum
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
FL (avian)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA