product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
MBNL1 (3A4) Antibody
catalog :
sc-47740
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3A4
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 7
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:500; fig 8
  • immunohistochemistry - frozen section; mouse; 1:500; fig 7
  • western blot; mouse; 1:1000; fig 7
Alves S, Marais T, Biferi M, Furling D, Marinello M, El Hachimi K, et al. Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins. Mol Neurodegener. 2016;11:58 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 4
Du J, Aleff R, Soragni E, Kalari K, Nie J, Tang X, et al. RNA toxicity and missplicing in the common eye disease fuchs endothelial corneal dystrophy. J Biol Chem. 2015;290:5979-90 pubmed publisher
Casci I, Krishnamurthy K, Kour S, Tripathy V, Ramesh N, Anderson E, et al. Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization. Nat Commun. 2019;10:5583 pubmed publisher
Li J, Choi P, Chaffer C, Labella K, Hwang J, Giacomelli A, et al. An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer. elife. 2018;7: pubmed publisher
Provenzano C, Cappella M, Valaperta R, Cardani R, Meola G, Martelli F, et al. CRISPR/Cas9-Mediated Deletion of CTG Expansions Recovers Normal Phenotype in Myogenic Cells Derived from Myotonic Dystrophy 1 Patients. Mol Ther Nucleic Acids. 2017;9:337-348 pubmed publisher
Coram R, Stillwagon S, Guggilam A, Jenkins M, Swanson M, Ladd A. Muscleblind-like 1 is required for normal heart valve development in vivo. BMC Dev Biol. 2015;15:36 pubmed publisher
Laurent F, Sureau A, Klein A, Trouslard F, Gasnier E, Furling D, et al. New function for the RNA helicase p68/DDX5 as a modifier of MBNL1 activity on expanded CUG repeats. Nucleic Acids Res. 2012;40:3159-71 pubmed publisher
product information
Catalog Number :
sc-47740
Product Name :
MBNL1 (3A4) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
3A4
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
MBNL1
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA