product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Rab 5 (D-11) Antibody
catalog :
sc-46692
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D-11
reactivity :
hamsters, human, mouse, rat, pigs , Xenopus laevis
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 29
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1a
Rivas S, SILVA P, Reyes M, Sepulveda H, Solano L, Acuña J, et al. The RabGEF ALS2 is a hypoxia inducible target associated with the acquisition of aggressive traits in tumor cells. Sci Rep. 2020;10:22302 pubmed publisher
  • immunocytochemistry; Xenopus laevis; 1:50; loading ...; fig 2a
Cioni J, Lin J, Holtermann A, Koppers M, Jakobs M, Azizi A, et al. Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons. Cell. 2019;176:56-72.e15 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig s2e
Yuan Q, Ren C, Xu W, Petri B, Zhang J, Zhang Y, et al. PKN1 Directs Polarized RAB21 Vesicle Trafficking via RPH3A and Is Important for Neutrophil Adhesion and Ischemia-Reperfusion Injury. Cell Rep. 2017;19:2586-2597 pubmed publisher
  • immunocytochemistry; pigs ; fig 3b
Kober A, Manavalan A, Tam Amersdorfer C, Holmér A, Saeed A, Fanaee Danesh E, et al. Implications of cerebrovascular ATP-binding cassette transporter G1 (ABCG1) and apolipoprotein M in cholesterol transport at the blood-brain barrier. Biochim Biophys Acta Mol Cell Biol Lipids. 2017;1862:573-588 pubmed publisher
  • western blot; mouse; loading ...; fig 6a
Koh H, Kim Y, Kim J, Yun J, Jang K, Yang C. Toxoplasma gondii GRA7-Targeted ASC and PLD1 Promote Antibacterial Host Defense via PKCα. PLoS Pathog. 2017;13:e1006126 pubmed publisher
  • immunocytochemistry; human; fig 3a
Zimmermann Meisse G, Prevost G, Jover E. Above and beyond C5a Receptor Targeting by Staphylococcal Leucotoxins: Retrograde Transport of Panton-Valentine Leucocidin and ?-Hemolysin. Toxins (Basel). 2017;9: pubmed publisher
  • immunoprecipitation; mouse; fig 2
  • immunocytochemistry; mouse; 1:300; fig 2
Jaber N, Mohd Naim N, Wang Z, Deleon J, Kim S, Zhong H, et al. Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus. J Cell Sci. 2016;129:4424-4435 pubmed
  • western blot; human; loading ...; fig 3a
Gräßel L, Fast L, Scheffer K, Boukhallouk F, Spoden G, Tenzer S, et al. The CD63-Syntenin-1 Complex Controls Post-Endocytic Trafficking of Oncogenic Human Papillomaviruses. Sci Rep. 2016;6:32337 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 7c
Luessen D, Hinshaw T, Sun H, Howlett A, MARRS G, McCool B, et al. RGS2 modulates the activity and internalization of dopamine D2 receptors in neuroblastoma N2A cells. Neuropharmacology. 2016;110:297-307 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 3
Oliveira Nunes M, Assad Kahn S, de Oliveira Barbeitas A, E Spohr T, Dubois L, Ventura Matioszek G, et al. The availability of the embryonic TGF-? protein Nodal is dynamically regulated during glioblastoma multiforme tumorigenesis. Cancer Cell Int. 2016;16:46 pubmed publisher
  • western blot; human; fig 1a
SILVA P, Mendoza P, Rivas S, Diaz J, Moraga C, Quest A, et al. Hypoxia promotes Rab5 activation, leading to tumor cell migration, invasion and metastasis. Oncotarget. 2016;7:29548-62 pubmed publisher
  • western blot; mouse; fig 1
Aizawa S, Fujiwara Y, Contu V, Hase K, Takahashi M, Kikuchi H, et al. Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes. Autophagy. 2016;12:565-78 pubmed publisher
  • western blot; human; loading ...; fig 5a
Takahashi Y, Tsotakos N, Liu Y, Young M, Serfass J, Tang Z, et al. The Bif-1-Dynamin 2 membrane fission machinery regulates Atg9-containing vesicle generation at the Rab11-positive reservoirs. Oncotarget. 2016;7:20855-68 pubmed publisher
  • immunocytochemistry; hamsters
Pastuszka M, Okamoto C, Hamm Alvarez S, MacKay J. Flipping the Switch on Clathrin-Mediated Endocytosis using Thermally Responsive Protein Microdomains. Adv Funct Mater. 2014;24:5340-5347 pubmed
Shin H, Jeong E, Lee J, An H, Jang H, Ahn Y, et al. Lipocalin-2 Deficiency Reduces Oxidative Stress and Neuroinflammation and Results in Attenuation of Kainic Acid-Induced Hippocampal Cell Death. Antioxidants (Basel). 2021;10: pubmed publisher
Martin S, Smolders S, Van den Haute C, Heeman B, van Veen S, Crosiers D, et al. Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export. Acta Neuropathol. 2020;139:1001-1024 pubmed publisher
Zhen Y, Spangenberg H, Munson M, Brech A, Schink K, Tan K, et al. ESCRT-mediated phagophore sealing during mitophagy. Autophagy. 2019;:1-16 pubmed publisher
Fang C, Manes T, Liu L, Liu K, Qin L, Li G, et al. ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes. Nat Commun. 2019;10:2247 pubmed publisher
Lenis T, Hu J, Ng S, Jiang Z, Sarfare S, Lloyd M, et al. Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration. Proc Natl Acad Sci U S A. 2018;115:E11120-E11127 pubmed publisher
Qiu S, Wu Y, Lv X, Li X, Zhuo M, Koga K. Reduced synaptic function of Kainate receptors in the insular cortex of Fmr1 Knock-out mice. Mol Brain. 2018;11:54 pubmed publisher
Sun Y, Chen C, Zhang P, Xie H, Hou L, Hui Z, et al. Reduced miR-3127-5p expression promotes NSCLC proliferation/invasion and contributes to dasatinib sensitivity via the c-Abl/Ras/ERK pathway. Sci Rep. 2014;4:6527 pubmed publisher
Qiu S, Chen T, Koga K, Guo Y, Xu H, Song Q, et al. An increase in synaptic NMDA receptors in the insular cortex contributes to neuropathic pain. Sci Signal. 2013;6:ra34 pubmed publisher
Steuble M, Diep T, Sch tzle P, Ludwig A, Tagaya M, Kunz B, et al. Calsyntenin-1 shelters APP from proteolytic processing during anterograde axonal transport. Biol Open. 2012;1:761-74 pubmed publisher
Wang Y, Wang J, Wang S, Liu S, Cao J, Li X, et al. Adaptor protein APPL1 couples synaptic NMDA receptor with neuronal prosurvival phosphatidylinositol 3-kinase/Akt pathway. J Neurosci. 2012;32:11919-29 pubmed publisher
Torres A, Fabani M, Vigorito E, Williams D, Al Obaidi N, Wojciechowski F, et al. Chemical structure requirements and cellular targeting of microRNA-122 by peptide nucleic acids anti-miRs. Nucleic Acids Res. 2012;40:2152-67 pubmed publisher
Rodriguez N, Gaur Dixit U, Allen L, Wilson M. Stage-specific pathways of Leishmania infantum chagasi entry and phagosome maturation in macrophages. PLoS ONE. 2011;6:e19000 pubmed publisher
Steuble M, Gerrits B, Ludwig A, Mateos J, Diep T, Tagaya M, et al. Molecular characterization of a trafficking organelle: dissecting the axonal paths of calsyntenin-1 transport vesicles. Proteomics. 2010;10:3775-88 pubmed publisher
Yoshida H, Okumura N, Kitagishi Y, Shirafuji N, Matsuda S. Rab5(Q79L) interacts with the carboxyl terminus of RUFY3. Int J Biol Sci. 2010;6:187-9 pubmed
Torres V, Mielgo A, Barilà D, Anderson D, Stupack D. Caspase 8 promotes peripheral localization and activation of Rab5. J Biol Chem. 2008;283:36280-9 pubmed publisher
product information
Product Name :
Rab 5 (D-11) Antibody
Gene Name :
RAB5A, RAB5B, RAB5C
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-46692
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Rab 5
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), ELISA
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA