product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
IGF-IRalpha (1H7) Antibody
catalog :
sc-461
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1H7
reactivity :
human, mouse, rat
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 6
Reference
Schayek H, Haugk K, Sun S, True L, Plymate S, Werner H. Tumor suppressor BRCA1 is expressed in prostate cancer and controls insulin-like growth factor I receptor (IGF-IR) gene transcription in an androgen receptor-dependent manner. Clin Cancer Res. 2009;15:1558-65 pubmed publisher
Wu J, Odman A, Higgins L, Haugk K, Vessella R, Ludwig D, et al. In vivo effects of the human type I insulin-like growth factor receptor antibody A12 on androgen-dependent and androgen-independent xenograft human prostate tumors. Clin Cancer Res. 2005;11:3065-74 pubmed
O'Neill A, Shah N, Zitomersky N, Ladanyi M, Shukla N, Uren A, et al. Insulin-like growth factor 1 receptor as a therapeutic target in ewing sarcoma: lack of consistent upregulation or recurrent mutation and a review of the clinical trial literature. Sarcoma. 2013;2013:450478 pubmed publisher
Wang J, Ohara N, Wang Z, Chen W, Morikawa A, Sasaki H, et al. A novel selective progesterone receptor modulator asoprisnil (J867) down-regulates the expression of EGF, IGF-I, TGFbeta3 and their receptors in cultured uterine leiomyoma cells. Hum Reprod. 2006;21:1869-77 pubmed
Warnken M, Reitzenstein U, Sommer A, Fuhrmann M, Mayer P, Enzmann H, et al. Characterization of proliferative effects of insulin, insulin analogues and insulin-like growth factor-1 (IGF-1) in human lung fibroblasts. Naunyn Schmiedebergs Arch Pharmacol. 2010;382:511-24 pubmed publisher
Plymate S, Haugk K, Coleman I, Woodke L, Vessella R, Nelson P, et al. An antibody targeting the type I insulin-like growth factor receptor enhances the castration-induced response in androgen-dependent prostate cancer. Clin Cancer Res. 2007;13:6429-39 pubmed
product information
Product Name :
IGF-IRalpha (1H7) Antibody
Gene Name :
IGF1R
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-461
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
IGF-IRalpha
reactive species  :
m, r, h
Application :
IP, IF, IHC(P), FCM
Epitope :
internal (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
www.scbt.com
1.800.457.3801
headquarters: USA