product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
HPV16 E6/18 E6 (C1P5) Antibody
catalog :
sc-460
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C1P5
reactivity :
Human papillomavirus, human, Human papillomavirus type 16
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:200; loading ...; fig 1c
Jin Y, Li Y, Wang X, Yang Y. Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways. Cancer Cell Int. 2019;19:220 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 1a
Kim S, Kim Y, Choi M, Kim M, Yang J, Park H, et al. O-linked-N-acetylglucosamine transferase is associated with metastatic spread of human papillomavirus E6 and E7 oncoproteins to the lungs of mice. Biochem Biophys Res Commun. 2017;483:793-802 pubmed publisher
  • western blot; Human papillomavirus type 16; 1:200; loading ...; fig 2b
Barillari G, Palladino C, Bacigalupo I, Leone P, Falchi M, Ensoli B. Entrance of the Tat protein of HIV-1 into human uterine cervical carcinoma cells causes upregulation of HPV-E6 expression and a decrease in p53 protein levels. Oncol Lett. 2016;12:2389-2394 pubmed
  • western blot; human
Mishra A, Kumar R, Tyagi A, Kohaar I, Hedau S, Bharti A, et al. Curcumin modulates cellular AP-1, NF-kB, and HPV16 E6 proteins in oral cancer. Ecancermedicalscience. 2015;9:525 pubmed publisher
  • western blot; Human papillomavirus; fig s1
Abuali G, Chaisaklert W, Stelloo E, Pazarentzos E, Hwang M, Qize D, et al. The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis. Oncogene. 2015;34:1718-28 pubmed publisher
Ju E, Li T, Ramos da Silva S, Gao S. Gold Nanocluster-Mediated Efficient Delivery of Cas9 Protein through pH-Induced Assembly-Disassembly for Inactivation of Virus Oncogenes. ACS Appl Mater Interfaces. 2019;11:34717-34724 pubmed publisher
Lionnard L, Duc P, Brennan M, Kueh A, Pal M, Guardia F, et al. TRIM17 and TRIM28 antagonistically regulate the ubiquitination and anti-apoptotic activity of BCL2A1. Cell Death Differ. 2019;26:902-917 pubmed publisher
Shankar S, Sreekumar A, Prasad D, Das A, Pillai M. Genome editing of oncogenes with ZFNs and TALENs: caveats in nuclease design. Cancer Cell Int. 2018;18:169 pubmed publisher
Ren C, Cheng X, Lu B, Yang G. Activation of interleukin-6/signal transducer and activator of transcription 3 by human papillomavirus early proteins 6 induces fibroblast senescence to promote cervical tumourigenesis through autocrine and paracrine pathways in tumour microenvironme. Eur J Cancer. 2013;49:3889-99 pubmed publisher
Roncaglia M, Fregnani J, Tacla M, de Campos S, Caiaffa H, Ab Saber A, et al. Characterization of p16 and E6 HPV-related proteins in uterine cervix high-grade lesions of patients treated by conization with large loop excision. Oncol Lett. 2013;6:63-68 pubmed
Li W, Anderson R. Star-PAP controls HPV E6 regulation of p53 and sensitizes cells to VP-16. Oncogene. 2014;33:928-32 pubmed publisher
Cen L, Carlson B, Schroeder M, Ostrem J, Kitange G, Mladek A, et al. p16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells. Neuro Oncol. 2012;14:870-81 pubmed publisher
Milrot E, Jackman A, Kniazhanski T, Gonen P, Flescher E, Sherman L. Methyl jasmonate reduces the survival of cervical cancer cells and downregulates HPV E6 and E7, and survivin. Cancer Lett. 2012;319:31-8 pubmed publisher
Hsu C, Peng K, Jhang H, Lin C, Wu S, Chiang C, et al. The HPV E6 oncoprotein targets histone methyltransferases for modulating specific gene transcription. Oncogene. 2012;31:2335-49 pubmed publisher
Jang M, Rhee J, Jang D, Kim S. Gene expression profiles are altered in human papillomavirus-16 E6 D25E-expressing cell lines. Virol J. 2011;8:453 pubmed publisher
Yew C, Lee P, Chan W, Lim V, Tay S, Tan T, et al. A novel MLL5 isoform that is essential to activate E6 and E7 transcription in HPV16/18-associated cervical cancers. Cancer Res. 2011;71:6696-707 pubmed publisher
Wang W, Sima N, Kong D, Luo A, Gao Q, Liao S, et al. Selective targeting of HPV-16 E6/E7 in cervical cancer cells with a potent oncolytic adenovirus and its enhanced effect with radiotherapy in vitro and vivo. Cancer Lett. 2010;291:67-75 pubmed publisher
Sima N, Wang W, Kong D, Deng D, Xu Q, Zhou J, et al. RNA interference against HPV16 E7 oncogene leads to viral E6 and E7 suppression in cervical cancer cells and apoptosis via upregulation of Rb and p53. Apoptosis. 2008;13:273-81 pubmed
Zhang P, Jacobs B, Samuel C. Loss of protein kinase PKR expression in human HeLa cells complements the vaccinia virus E3L deletion mutant phenotype by restoration of viral protein synthesis. J Virol. 2008;82:840-8 pubmed
Sima N, Wang S, Wang W, Kong D, Xu Q, Tian X, et al. Antisense targeting human papillomavirus type 16 E6 and E7 genes contributes to apoptosis and senescence in SiHa cervical carcinoma cells. Gynecol Oncol. 2007;106:299-304 pubmed
Shuyama K, Castillo A, Aguayo F, Sun Q, Khan N, Koriyama C, et al. Human papillomavirus in high- and low-risk areas of oesophageal squamous cell carcinoma in China. Br J Cancer. 2007;96:1554-9 pubmed
Sdek P, Zhang Z, Cao J, Pan H, Chen W, Zheng J. Alteration of cell-cycle regulatory proteins in human oral epithelial cells immortalized by HPV16 E6 and E7. Int J Oral Maxillofac Surg. 2006;35:653-7 pubmed
Valdespino V, Gorodezky C, Ortiz V, Kaufmann A, Román Basaure E, Vazquez A, et al. HPV16-specific cytotoxic T lymphocyte responses are detected in all HPV16-positive cervical cancer patients. Gynecol Oncol. 2005;96:92-102 pubmed
product information
Product Name :
HPV16 E6/18 E6 (C1P5) Antibody
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-460
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
HPV16 E6/18 E6
reactive species  :
HPV-16, HPV-18
Application :
WB, IP, IF, IHC(P)
Epitope :
HPV E6 (v)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA