product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Fyn (15) Antibody
catalog :
sc-434
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
15
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; rat
Peckham H, Giuffrida L, Wood R, Gonsalvez D, Ferner A, Kilpatrick T, et al. Fyn is an intermediate kinase that BDNF utilizes to promote oligodendrocyte myelination. Glia. 2016;64:255-69 pubmed publisher
  • immunoprecipitation; human
Corvetta D, Chayka O, Gherardi S, D'Acunto C, Cantilena S, Valli E, et al. Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: functional and therapeutic implications. J Biol Chem. 2013;288:8332-41 pubmed publisher
Tong W, Maira M, Gagnon M, Saragovi H. Ligands Binding to Cell Surface Ganglioside GD2 Cause Src-Dependent Activation of N-Methyl-D-Aspartate Receptor Signaling and Changes in Cellular Morphology. PLoS ONE. 2015;10:e0134255 pubmed publisher
Thien C, Dagger S, Steer J, Koentgen F, Jansen E, Scott C, et al. c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway. J Biol Chem. 2010;285:10969-81 pubmed publisher
García-Román J, Ibarra-Sánchez A, Lamas M, Gonzalez Espinosa C. VEGF secretion during hypoxia depends on free radicals-induced Fyn kinase activity in mast cells. Biochem Biophys Res Commun. 2010;401:262-7 pubmed publisher
Weinlich S, Huttelmaier S, Schierhorn A, Behrens S, Ostareck-Lederer A, Ostareck D. IGF2BP1 enhances HCV IRES-mediated translation initiation via the 3'UTR. RNA. 2009;15:1528-42 pubmed publisher
Ko M, Zou K, Minagawa H, Yu W, Gong J, Yanagisawa K, et al. Cholesterol-mediated neurite outgrowth is differently regulated between cortical and hippocampal neurons. J Biol Chem. 2005;280:42759-65 pubmed
Flores O, Pérez H, Valladares L, Morgan C, Gatica A, Burgos H, et al. Hidden prenatal malnutrition in the rat: role of β₁-adrenoceptors on synaptic plasticity in the frontal cortex. J Neurochem. 2011;119:314-23 pubmed publisher
Yadav V, Denning M. Fyn is induced by Ras/PI3K/Akt signaling and is required for enhanced invasion/migration. Mol Carcinog. 2011;50:346-52 pubmed publisher
Vacaresse N, Møller B, Danielsen E, Okada M, Sap J. Activation of c-Src and Fyn kinases by protein-tyrosine phosphatase RPTPalpha is substrate-specific and compatible with lipid raft localization. J Biol Chem. 2008;283:35815-24 pubmed publisher
Miyamoto Y, Chen L, Sato M, Sokabe M, Nabeshima T, Pawson T, et al. Hippocampal synaptic modulation by the phosphotyrosine adapter protein ShcC/N-Shc via interaction with the NMDA receptor. J Neurosci. 2005;25:1826-35 pubmed
Farina F, Botto L, Chinello C, Cunati D, Magni F, Masserini M, et al. Characterization of prion protein-enriched domains, isolated from rat cerebellar granule cells in culture. J Neurochem. 2009;110:1038-48 pubmed publisher
Sánchez-Miranda E, Ibarra-Sánchez A, Gonzalez-Espinosa C. Fyn kinase controls FcepsilonRI receptor-operated calcium entry necessary for full degranulation in mast cells. Biochem Biophys Res Commun. 2010;391:1714-20 pubmed publisher
Chen X, Jen A, Warley A, Lawrence M, Quinn P, Morris R. Isolation at physiological temperature of detergent-resistant membranes with properties expected of lipid rafts: the influence of buffer composition. Biochem J. 2009;417:525-33 pubmed publisher
Petit-Paitel A, Ménard B, Guyon A, Beringue V, Nahon J, Zsurger N, et al. Prion protein is a key determinant of alcohol sensitivity through the modulation of N-methyl-D-aspartate receptor (NMDAR) activity. PLoS ONE. 2012;7:e34691 pubmed publisher
product information
Product Name :
Fyn (15) Antibody
Gene Name :
FYN
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-434
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Fyn
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P), FCM
Epitope :
85-206 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
www.scbt.com
1.800.457.3801
headquarters: USA