product summary
Loading...
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Lck (3A5) AC
catalog :
sc-433 AC
quantity :
500 µg/ml, 25% ag
price :
416 USD
clonality :
monoclonal
host :
mouse
conjugate :
agarose
clone name :
3A5
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig s7
Li L, Guo X, Shi X, Li C, Wu W, Yan C, et al. Ionic CD3-Lck interaction regulates the initiation of T-cell receptor signaling. Proc Natl Acad Sci U S A. 2017;114:E5891-E5899 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1a
Silva J, Martins N, Henriques R, Soares H. HIV-1 Nef Impairs the Formation of Calcium Membrane Territories Controlling the Signaling Nanoarchitecture at the Immunological Synapse. J Immunol. 2016;197:4042-4052 pubmed
  • flow cytometry; human; fig 1c
Trautz B, Pierini V, Wombacher R, Stolp B, Chase A, Pizzato M, et al. The Antagonism of HIV-1 Nef to SERINC5 Particle Infectivity Restriction Involves the Counteraction of Virion-Associated Pools of the Restriction Factor. J Virol. 2016;90:10915-10927 pubmed publisher
  • western blot; human; loading ...; fig 3a
Stikvoort A, Sundin M, Uzunel M, Gertow J, Sundberg B, Schaffer M, et al. Long-Term Stable Mixed Chimerism after Hematopoietic Stem Cell Transplantation in Patients with Non-Malignant Disease, Shall We Be Tolerant?. PLoS ONE. 2016;11:e0154737 pubmed publisher
  • western blot; mouse; fig 5
Hu H, Wang H, Xiao Y, Jin J, Chang J, Zou Q, et al. Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination. J Exp Med. 2016;213:399-414 pubmed publisher
  • western blot; mouse; fig 6a
Zou Q, Jin J, Xiao Y, Hu H, Zhou X, Jie Z, et al. T cell development involves TRAF3IP3-mediated ERK signaling in the Golgi. J Exp Med. 2015;212:1323-36 pubmed publisher
  • western blot; human
Kloog Y, Mor A. Cytotoxic-T-lymphocyte antigen 4 receptor signaling for lymphocyte adhesion is mediated by C3G and Rap1. Mol Cell Biol. 2014;34:978-88 pubmed publisher
  • western blot; human
Paster W, Brockmeyer C, Fu G, Simister P, de Wet B, Martinez Riaño A, et al. GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development. J Immunol. 2013;190:3749-56 pubmed publisher
Silva O, Crocetti J, Humphries L, Burkhardt J, Miceli M. Discs Large Homolog 1 Splice Variants Regulate p38-Dependent and -Independent Effector Functions in CD8+ T Cells. PLoS ONE. 2015;10:e0133353 pubmed publisher
Sakamoto T, Kobayashi M, Tada K, Shinohara M, Io K, Nagata K, et al. CKIP-1 is an intrinsic negative regulator of T-cell activation through an interaction with CARMA1. PLoS ONE. 2014;9:e85762 pubmed publisher
Rajasekaran K, Kumar P, Schuldt K, Peterson E, Vanhaesebroeck B, Dixit V, et al. Signaling by Fyn-ADAP via the Carma1-Bcl-10-MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells. Nat Immunol. 2013;14:1127-36 pubmed publisher
Emaduddin M, Edelmann M, Kessler B, Feller S. Odin (ANKS1A) is a Src family kinase target in colorectal cancer cells. Cell Commun Signal. 2008;6:7 pubmed publisher
Marti F, Garcia G, Lapinski P, Macgregor J, King P. Essential role of the T cell-specific adapter protein in the activation of LCK in peripheral T cells. J Exp Med. 2006;203:281-7 pubmed
product information
Catalog Number :
sc-433 AC
Product Name :
Lck (3A5) AC
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Conjugation :
agarose
Clone Name :
3A5
Isotype :
IgG2b
Size :
500 µg/ml, 25% ag
List Price :
416 USD
Immunogen :
Lck
Specificity :
mouse, rat, human
Uses :
IP
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA