product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
c-Myc (C-33) Antibody
catalog :
sc-42
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-33
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 50
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4e
Song X, Chen H, Zhang C, Yu Y, Chen Z, Liang H, et al. SRC-3 inhibition blocks tumor growth of pancreatic ductal adenocarcinoma. Cancer Lett. 2019;442:310-319 pubmed publisher
  • western blot; human; loading ...; fig 1a
Rossetti S, Wierzbicki A, Sacchi N. Undermining ribosomal RNA transcription in both the nucleolus and mitochondrion: an offbeat approach to target MYC-driven cancer. Oncotarget. 2018;9:5016-5031 pubmed publisher
  • western blot; human; fig 6
Mitxelena J, Apraiz A, Vallejo Rodríguez J, Malumbres M, Zubiaga A. E2F7 regulates transcription and maturation of multiple microRNAs to restrain cell proliferation. Nucleic Acids Res. 2016;: pubmed
  • western blot; mouse; 1:500; fig 6
Morrison G, Scognamiglio R, Trumpp A, Smith A. Convergence of cMyc and β-catenin on Tcf7l1 enables endoderm specification. EMBO J. 2016;35:356-68 pubmed publisher
  • western blot; human; fig s3
Xiao D, Ren P, Su H, Yue M, Xiu R, Hu Y, et al. Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2. Oncotarget. 2015;6:40655-66 pubmed publisher
  • western blot; mouse; fig 1
Hunter J, Butterworth J, Zhao B, Sellier H, Campbell K, Thomas H, et al. The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma. Oncogene. 2016;35:3476-84 pubmed publisher
  • western blot; human; loading ...; fig 7b
Rebucci M, Sermeus A, Leonard E, Delaive E, Dieu M, Fransolet M, et al. miRNA-196b inhibits cell proliferation and induces apoptosis in HepG2 cells by targeting IGF2BP1. Mol Cancer. 2015;14:79 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6e
Li Y, Wu Y, Abbatiello T, Wu W, Kim J, Sarkissyan M, et al. Slug contributes to cancer progression by direct regulation of ERα signaling pathway. Int J Oncol. 2015;46:1461-72 pubmed publisher
Ren S, Wang J, Chen T, Li H, Wan Y, Peng N, et al. Hepatitis B Virus Stimulated Fibronectin Facilitates Viral Maintenance and Replication through Two Distinct Mechanisms. PLoS ONE. 2016;11:e0152721 pubmed publisher
Costales M, Lopez F, García Inclán C, Fernandez S, Marcos C, Llorente J, et al. Establishment and characterization of an orthotopic sinonasal squamous cell carcinoma mouse model. Head Neck. 2015;37:1769-75 pubmed publisher
Inturi R, Thaduri S, Punga T. Adenovirus precursor pVII protein stability is regulated by its propeptide sequence. PLoS ONE. 2013;8:e80617 pubmed publisher
Wiegering A, Pfann C, Uthe F, Otto C, Rycak L, Mäder U, et al. CIP2A influences survival in colon cancer and is critical for maintaining Myc expression. PLoS ONE. 2013;8:e75292 pubmed publisher
Song G, Li Y, Zhang Z, Ren X, Li H, Zhang W, et al. c-myc but not Hif-1?-dependent downregulation of VEGF influences the proliferation and differentiation of HL-60 cells induced by ATRA. Oncol Rep. 2013;29:2378-84 pubmed publisher
Mannava S, Moparthy K, Wheeler L, Leonova K, Wawrzyniak J, Bianchi Smiraglia A, et al. Ribonucleotide reductase and thymidylate synthase or exogenous deoxyribonucleosides reduce DNA damage and senescence caused by C-MYC depletion. Aging (Albany NY). 2012;4:917-22 pubmed
Mannava S, Moparthy K, Wheeler L, Natarajan V, Zucker S, Fink E, et al. Depletion of deoxyribonucleotide pools is an endogenous source of DNA damage in cells undergoing oncogene-induced senescence. Am J Pathol. 2013;182:142-51 pubmed publisher
Cattoretti G. MYC expression and distribution in normal mature lymphoid cells. J Pathol. 2013;229:430-40 pubmed publisher
Hwang J, Ting W, Wu H, Chen Y, Tsai F, Chen P, et al. KHC-4 anti-cancer effects on human PC3 prostate cancer cell line. Am J Chin Med. 2012;40:1063-71 pubmed publisher
Weltner J, Anisimov A, Alitalo K, Otonkoski T, Trokovic R. Induced pluripotent stem cell clones reprogrammed via recombinant adeno-associated virus-mediated transduction contain integrated vector sequences. J Virol. 2012;86:4463-7 pubmed publisher
Zushi Y, Narisawa Saito M, Noguchi K, Yoshimatsu Y, Yugawa T, Egawa N, et al. An in vitro multistep carcinogenesis model for both HPV-positive and -negative human oral squamous cell carcinomas. Am J Cancer Res. 2011;1:869-81 pubmed
Xiao D, Dai B, Chen J, Luo Q, Liu X, Lin Q, et al. Loss of macrophage migration inhibitory factor impairs the growth properties of human HeLa cervical cancer cells. Cell Prolif. 2011;44:582-90 pubmed publisher
Ferreira A, Suriano G, Mendes N, Gomes B, Wen X, Carneiro F, et al. E-cadherin impairment increases cell survival through Notch-dependent upregulation of Bcl-2. Hum Mol Genet. 2012;21:334-43 pubmed publisher
Trabzuni D, Ryten M, Walker R, Smith C, Imran S, Ramasamy A, et al. Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies. J Neurochem. 2011;119:275-82 pubmed publisher
Mannava S, Omilian A, Wawrzyniak J, Fink E, Zhuang D, Miecznikowski J, et al. PP2A-B56? controls oncogene-induced senescence in normal and tumor human melanocytic cells. Oncogene. 2012;31:1484-92 pubmed publisher
Mathiasen D, Egebjerg C, Andersen S, Rafn B, Puustinen P, Khanna A, et al. Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation. Oncogene. 2012;31:390-401 pubmed publisher
Furukawa K, Sato T, Katsuno T, Nakagawa T, Noguchi Y, Tokumasa A, et al. Smad3 contributes to positioning of proliferating cells in colonic crypts by inducing EphB receptor protein expression. Biochem Biophys Res Commun. 2011;405:521-6 pubmed publisher
Amodio N, Scrima M, Palaia L, Salman A, Quintiero A, Franco R, et al. Oncogenic role of the E3 ubiquitin ligase NEDD4-1, a PTEN negative regulator, in non-small-cell lung carcinomas. Am J Pathol. 2010;177:2622-34 pubmed publisher
Noack J, Richter K, Laube G, Haghgoo H, Veh R, Engelmann M. Different importance of the volatile and non-volatile fractions of an olfactory signature for individual social recognition in rats versus mice and short-term versus long-term memory. Neurobiol Learn Mem. 2010;94:568-75 pubmed publisher
Riz I, Hawley T, Luu T, Lee N, Hawley R. TLX1 and NOTCH coregulate transcription in T cell acute lymphoblastic leukemia cells. Mol Cancer. 2010;9:181 pubmed publisher
Kamata M, Liu S, Liang M, Nagaoka Y, Chen I. Generation of human induced pluripotent stem cells bearing an anti-HIV transgene by a lentiviral vector carrying an internal murine leukemia virus promoter. Hum Gene Ther. 2010;21:1555-67 pubmed publisher
Mattison J, Kool J, Uren A, de Ridder J, Wessels L, Jonkers J, et al. Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach. Cancer Res. 2010;70:883-95 pubmed publisher
Hu Z, Sun J, Zhu X, Yang D, Zeng Y. ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway. J Transl Med. 2009;7:74 pubmed publisher
Robinson K, Asawachaicharn N, Galloway D, Grandori C. c-Myc accelerates S-phase and requires WRN to avoid replication stress. PLoS ONE. 2009;4:e5951 pubmed publisher
Jüch M, Smalla K, Kahne T, Lubec G, Tischmeyer W, Gundelfinger E, et al. Congenital lack of nNOS impairs long-term social recognition memory and alters the olfactory bulb proteome. Neurobiol Learn Mem. 2009;92:469-84 pubmed publisher
Laurent B, Randrianarison Huetz V, Kadri Z, Romeo P, Porteu F, Dumenil D. Gfi-1B promoter remains associated with active chromatin marks throughout erythroid differentiation of human primary progenitor cells. Stem Cells. 2009;27:2153-62 pubmed publisher
Foreman J, Sorg J, McGinnis K, Rigas B, Williams J, Clapper M, et al. Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs. Mol Carcinog. 2009;48:942-52 pubmed publisher
Sasaki R, Narisawa Saito M, Yugawa T, Fujita M, Tashiro H, Katabuchi H, et al. Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes. Carcinogenesis. 2009;30:423-31 pubmed publisher
Shi Y, FROST P, Hoang B, Benavides A, Sharma S, Gera J, et al. IL-6-induced stimulation of c-myc translation in multiple myeloma cells is mediated by myc internal ribosome entry site function and the RNA-binding protein, hnRNP A1. Cancer Res. 2008;68:10215-22 pubmed publisher
Hrdlicková R, Nehyba J, Bose H. Regulation of telomerase activity by interferon regulatory factors 4 and 8 in immune cells. Mol Cell Biol. 2009;29:929-41 pubmed publisher
Zhu C, Li C, Li Y, Zhan Y, Li Y, Xu C, et al. Cell growth suppression by thanatos-associated protein 11(THAP11) is mediated by transcriptional downregulation of c-Myc. Cell Death Differ. 2009;16:395-405 pubmed publisher
Zheng H, Ying H, Yan H, Kimmelman A, Hiller D, Chen A, et al. p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature. 2008;455:1129-33 pubmed publisher
Engelmann M. Competition between two memory traces for long-term recognition memory. Neurobiol Learn Mem. 2009;91:58-65 pubmed publisher
Mannava S, Grachtchouk V, Wheeler L, Im M, Zhuang D, Slavina E, et al. Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells. Cell Cycle. 2008;7:2392-400 pubmed
Sermeus A, Cosse J, Crespin M, Mainfroid V, de Longueville F, Ninane N, et al. Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity. Mol Cancer. 2008;7:27 pubmed publisher
Nakanishi H, Groskopf J, Fritsche H, Bhadkamkar V, Blase A, Kumar S, et al. PCA3 molecular urine assay correlates with prostate cancer tumor volume: implication in selecting candidates for active surveillance. J Urol. 2008;179:1804-9; discussion 1809-10 pubmed publisher
Dubayle D, Serviere J, Menetrey D. The effects of viscero-somatic interactions on thalamic mast cell recruitment in cystitic rats. J Neuroimmunol. 2007;190:18-27 pubmed
Zada A, Pulikkan J, Bararia D, Geletu M, Trivedi A, Balkhi M, et al. Proteomic discovery of Max as a novel interacting partner of C/EBPalpha: a Myc/Max/Mad link. Leukemia. 2006;20:2137-46 pubmed
Cope G, Deshaies R. Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels. BMC Biochem. 2006;7:1 pubmed
Liu J, Xie Y, Merrick B, Shen J, Ducharme D, Collins J, et al. Transplacental arsenic plus postnatal 12-O-teradecanoyl phorbol-13-acetate exposures associated with hepatocarcinogenesis induce similar aberrant gene expression patterns in male and female mouse liver. Toxicol Appl Pharmacol. 2006;213:216-23 pubmed
Richter K, Wolf G, Engelmann M. Social recognition memory requires two stages of protein synthesis in mice. Learn Mem. 2005;12:407-13 pubmed
Telfer J, Urquhart J, Crouch D. Suppression of MEK/ERK signalling by Myc: role of Bin-1. Cell Signal. 2005;17:701-8 pubmed
product information
Catalog Number :
sc-42
Product Name :
c-Myc (C-33) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
C-33
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
c-Myc
Specificity :
mouse, rat, human, avian
Uses :
WB, IP, IF, ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA