product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Rho A (26C4) AC
catalog :
sc-418 AC
quantity :
500 µg/ml, 25% ag
price :
416 USD
clonality :
monoclonal
host :
mouse
conjugate :
agarose
clone name :
26C4
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3a
Bobo Jiménez V, Delgado Esteban M, Angibaud J, Sánchez Morán I, de la Fuente A, Yajeya J, et al. APC/CCdh1-Rock2 pathway controls dendritic integrity and memory. Proc Natl Acad Sci U S A. 2017;114:4513-4518 pubmed publisher
  • western blot; mouse; loading ...; fig s10b
Hodgson L, Spiering D, Sabouri Ghomi M, Dagliyan O, DerMardirossian C, Danuser G, et al. FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions. Nat Chem Biol. 2016;12:802-809 pubmed publisher
  • western blot; human; fig 6c
Muramatsu T, Kozaki K, Imoto S, Yamaguchi R, Tsuda H, Kawano T, et al. The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma. Oncogene. 2016;35:5304-5316 pubmed publisher
  • western blot; human; loading ...; fig 1
Ferru Clément R, Fresquet F, Norez C, Métayé T, Becq F, Kitzis A, et al. Involvement of the Cdc42 pathway in CFTR post-translational turnover and in its plasma membrane stability in airway epithelial cells. PLoS ONE. 2015;10:e0118943 pubmed publisher
  • western blot; rat
Segatto M, Manduca A, Lecis C, Rosso P, Jozwiak A, Swiezewska E, et al. Simvastatin treatment highlights a new role for the isoprenoid/cholesterol biosynthetic pathway in the modulation of emotional reactivity and cognitive performance in rats. Neuropsychopharmacology. 2014;39:841-54 pubmed publisher
  • immunocytochemistry; human; 1:100
  • western blot; human; 1:1000
Kitagawa M, Fung S, Onishi N, Saya H, Lee S. Targeting Aurora B to the equatorial cortex by MKlp2 is required for cytokinesis. PLoS ONE. 2013;8:e64826 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Stergiou L, Bauer M, Mair W, Bausch Fluck D, Drayman N, Wollscheid B, et al. Integrin-mediated signaling induced by simian virus 40 leads to transient uncoupling of cortical actin and the plasma membrane. PLoS ONE. 2013;8:e55799 pubmed publisher
  • western blot; mouse; 1:250; fig 7
MARCIANO D, BRAKEMAN P, Lee C, Spivak N, Eastburn D, Bryant D, et al. p120 catenin is required for normal renal tubulogenesis and glomerulogenesis. Development. 2011;138:2099-109 pubmed publisher
van de Ven R, de Groot J, Park D, van Domselaar R, de Jong D, Szuhai K, et al. p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis. Nat Commun. 2016;7:13874 pubmed publisher
Gaitanos T, Koerner J, Klein R. Tiam-Rac signaling mediates trans-endocytosis of ephrin receptor EphB2 and is important for cell repulsion. J Cell Biol. 2016;214:735-52 pubmed publisher
Lee S, Jo Y, Namgoong S, Kim N. Anillin controls cleavage furrow formation in the course of asymmetric division during mouse oocyte maturation. Mol Reprod Dev. 2016;83:792-801 pubmed publisher
Liu S, Zhou F, Shen Y, Zhang Y, Yin H, Zeng Y, et al. Fluid shear stress induces epithelial-mesenchymal transition (EMT) in Hep-2 cells. Oncotarget. 2016;7:32876-92 pubmed publisher
Koch J, Tönges L, Michel U, Bähr M, Lingor P. Viral vector-mediated downregulation of RhoA increases survival and axonal regeneration of retinal ganglion cells. Front Cell Neurosci. 2014;8:273 pubmed publisher
Siegert P, Schmidt G, Papatheodorou P, Wieland T, Aktories K, Orth J. Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase cascade via the G?(q/11)--p63RhoGEF--RhoA axis. PLoS Pathog. 2013;9:e1003385 pubmed publisher
Greciano P, Moyano J, Buschmann M, Tang J, Lu Y, Rudnicki J, et al. Laminin 511 partners with laminin 332 to mediate directional migration of Madin-Darby canine kidney epithelial cells. Mol Biol Cell. 2012;23:121-36 pubmed publisher
Vega F, Fruhwirth G, Ng T, Ridley A. RhoA and RhoC have distinct roles in migration and invasion by acting through different targets. J Cell Biol. 2011;193:655-65 pubmed publisher
Cordeiro J, Guerra S, Arakawa Y, Dodding M, Esteban M, Way M. F11-mediated inhibition of RhoA signalling enhances the spread of vaccinia virus in vitro and in vivo in an intranasal mouse model of infection. PLoS ONE. 2009;4:e8506 pubmed publisher
Cinnamon Y, Feine O, Hochegger H, Bershadsky A, Brandeis M. Cellular contractility requires ubiquitin mediated proteolysis. PLoS ONE. 2009;4:e6155 pubmed publisher
Goffinet M, Chinestra P, Lajoie Mazenc I, Medale Giamarchi C, Favre G, Faye J. Identification of a GTP-bound Rho specific scFv molecular sensor by phage display selection. BMC Biotechnol. 2008;8:34 pubmed publisher
Gil Henn H, Destaing O, Sims N, Aoki K, Alles N, Neff L, et al. Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice. J Cell Biol. 2007;178:1053-64 pubmed
Kuribayashi K, Nakamura K, Tanaka M, Sato T, Kato J, Sasaki K, et al. Essential role of protein kinase C zeta in transducing a motility signal induced by superoxide and a chemotactic peptide, fMLP. J Cell Biol. 2007;176:1049-60 pubmed
Yanagisawa M, Anastasiadis P. p120 catenin is essential for mesenchymal cadherin-mediated regulation of cell motility and invasiveness. J Cell Biol. 2006;174:1087-96 pubmed
Dunn S, Youssef S, Goldstein M, Prod homme T, Weber M, Zamvil S, et al. Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin. J Exp Med. 2006;203:401-12 pubmed
Schubert V, Da Silva J, Dotti C. Localized recruitment and activation of RhoA underlies dendritic spine morphology in a glutamate receptor-dependent manner. J Cell Biol. 2006;172:453-67 pubmed
Oceguera Yanez F, Kimura K, Yasuda S, Higashida C, Kitamura T, Hiraoka Y, et al. Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis. J Cell Biol. 2005;168:221-32 pubmed
Danen E, Sonneveld P, Brakebusch C, Fassler R, Sonnenberg A. The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis. J Cell Biol. 2002;159:1071-86 pubmed
Corre I, Gomez M, Vielkind S, Cantrell D. Analysis of thymocyte development reveals that the GTPase RhoA is a positive regulator of T cell receptor responses in vivo. J Exp Med. 2001;194:903-14 pubmed
product information
Catalog Number :
sc-418 AC
Product Name :
Rho A (26C4) AC
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Conjugation :
agarose
Clone Name :
26C4
Isotype :
IgG1
Size :
500 µg/ml, 25% ag
List Price :
416 USD
Immunogen :
Rho A
Specificity :
mouse, rat, human
Uses :
IP
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA