product summary
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company name :
Santa Cruz Biotechnology
product type :
gene knockdown
product name :
SIRT1 siRNA (h)
catalog :
sc-40986
quantity :
10 µM
price :
293 USD
citations: 13
Reference
Shin D, Jo J, Choi M, Kim K, Bae Y, Kim S. Oncogenic KRAS mutation confers chemoresistance by upregulating SIRT1 in non-small cell lung cancer. Exp Mol Med. 2023;55:2220-2237 pubmed publisher
Zhang S, Wang J, Wang L, Aliyari S, Cheng G. SARS-CoV-2 virus NSP14 Impairs NRF2/HMOX1 activation by targeting Sirtuin 1. Cell Mol Immunol. 2022;: pubmed publisher
Yuan F, Wang J, Li R, Zhao X, Zhang Y, Liu B, et al. A New Regulatory Mechanism Between P53 And YAP Crosstalk By SIRT1 Mediated Deacetylation To Regulate Cell Cycle And Apoptosis In A549 Cell Lines. Cancer Manag Res. 2019;11:8619-8633 pubmed publisher
Wang X, Wang B, Zhao J, Liu C, Qu X, Li Y. MiR-155 is involved in major depression disorder and antidepressant treatment via targeting SIRT1. Biosci Rep. 2018;38: pubmed publisher
Salazar González R, Turiján Espinoza E, Hein D, Milán Segovia R, Uresti Rivera E, Portales Pérez D. Expression and genotype-dependent catalytic activity of N-acetyltransferase 2 (NAT2) in human peripheral blood mononuclear cells and its modulation by Sirtuin 1. Biochem Pharmacol. 2018;156:340-347 pubmed publisher
Mohibi S, Srivastava S, Bele A, Mirza S, Band H, Band V. Acetylation of Mammalian ADA3 Is Required for Its Functional Roles in Histone Acetylation and Cell Proliferation. Mol Cell Biol. 2016;36:2487-502 pubmed publisher
Guo P, Pi H, Xu S, Zhang L, Li Y, Li M, et al. Melatonin Improves mitochondrial function by promoting MT1/SIRT1/PGC-1 alpha-dependent mitochondrial biogenesis in cadmium-induced hepatotoxicity in vitro. Toxicol Sci. 2014;142:182-95 pubmed publisher
Thompson A, Martin K, Rzucidlo E. Resveratrol induces vascular smooth muscle cell differentiation through stimulation of SirT1 and AMPK. PLoS ONE. 2014;9:e85495 pubmed publisher
Becatti M, Fiorillo C, Barygina V, Cecchi C, Lotti T, Prignano F, et al. SIRT1 regulates MAPK pathways in vitiligo skin: insight into the molecular pathways of cell survival. J Cell Mol Med. 2014;18:514-29 pubmed publisher
Yang H, Zheng Y, Li T, Peng H, Fernandez Ramos D, Martinez Chantar M, et al. Methionine adenosyltransferase 2B, HuR, and sirtuin 1 protein cross-talk impacts on the effect of resveratrol on apoptosis and growth in liver cancer cells. J Biol Chem. 2013;288:23161-70 pubmed publisher
Xie M, Liu M, He C. SIRT1 regulates endothelial Notch signaling in lung cancer. PLoS ONE. 2012;7:e45331 pubmed publisher
Pinchot S, Jaskula Sztul R, Ning L, Peters N, Cook M, Kunnimalaiyaan M, et al. Identification and validation of Notch pathway activating compounds through a novel high-throughput screening method. Cancer. 2011;117:1386-98 pubmed publisher
Cao C, Lu S, Kivlin R, Wallin B, Card E, Bagdasarian A, et al. SIRT1 confers protection against UVB- and H2O2-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes. J Cell Mol Med. 2009;13:3632-43 pubmed publisher
product information
Catalog Number :
sc-40986
Product Name :
SIRT1 siRNA (h)
Product Type :
siRNA
Size :
10 µM
List Price :
293 USD
Immunogen :
SIRT1
Specificity :
human
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA