| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; 1:1000; fig s8
| Dick M, Sborgi L, Rühl S, Hiller S, Broz P. ASC filament formation serves as a signal amplification mechanism for inflammasomes. Nat Commun. 2016;7:11929 pubmed publisher |
- western blot; mouse; loading ...; fig 1d
| Chen R, Zeng L, Zhu S, Liu J, Zeh H, Kroemer G, et al. cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis. Sci Adv. 2019;5:eaav5562 pubmed publisher |
- western blot; mouse; loading ...; fig 8c
| Faliti C, Gualtierotti R, Rottoli E, Gerosa M, Perruzza L, Romagnani A, et al. P2X7 receptor restrains pathogenic Tfh cell generation in systemic lupus erythematosus. J Exp Med. 2019;216:317-336 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 1d
| Chen Y, Qin X, An Q, Yi J, Feng F, Yin D, et al. Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes. EBioMedicine. 2018;32:31-42 pubmed publisher |
- western blot; human; fig 6c
| Cheng K, Xiong S, Ye Z, Hong Z, Di A, Tsang K, et al. Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury. J Clin Invest. 2017;127:4124-4135 pubmed publisher |
- western blot; human; loading ...; fig 2d
| Rogers C, Fernandes Alnemri T, Mayes L, Alnemri D, Cingolani G, Alnemri E. Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death. Nat Commun. 2017;8:14128 pubmed publisher |
- immunoprecipitation; mouse; fig 3B
- western blot; mouse; 0.4 ug/ml; fig 3B
| Russo H, Rathkey J, Boyd Tressler A, Katsnelson M, Abbott D, Dubyak G. Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides. J Immunol. 2016;197:1353-67 pubmed publisher |
| Doke T, Huang S, Qiu C, Sheng X, Seasock M, Liu H, et al. Genome-wide association studies identify the role of caspase-9 in kidney disease. Sci Adv. 2021;7:eabi8051 pubmed publisher |
| Liu Z, Wang C, Yang J, Chen Y, Zhou B, Abbott D, et al. Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage. Immunity. 2020;53:106-114.e5 pubmed publisher |
| Rathkey J, Benson B, Chirieleison S, Yang J, Xiao T, Dubyak G, et al. Live-cell visualization of gasdermin D-driven pyroptotic cell death. J Biol Chem. 2017;292:14649-14658 pubmed publisher |
