product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
GR (G-5) Antibody
catalog :
sc-393232
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G-5
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 15
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 3d
  • western blot; human; loading ...; fig 3e
Song S, Jang W, Jang E, Kim O, Kim H, Son T, et al. Striatal miR-183-5p inhibits methamphetamine-induced locomotion by regulating glucocorticoid receptor signaling. Front Pharmacol. 2022;13:997701 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s6d
Nataraj N, Noronha A, Lee J, Ghosh S, Mohan Raju H, Sekar A, et al. Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors. Cell Rep. 2022;38:110418 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 5c
  • western blot; mouse; loading ...; fig s8
Timmermans S, Verhoog N, Van Looveren K, Dewaele S, Hochepied T, Eggermont M, et al. Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding. J Biol Chem. 2022;298:101574 pubmed publisher
  • chromatin immunoprecipitation; mouse; loading ...; fig 1b
Chen T, Kuo T, Dandan M, Lee R, Chang M, Villivalam S, et al. The role of striated muscle Pik3r1 in glucose and protein metabolism following chronic glucocorticoid exposure. J Biol Chem. 2021;296:100395 pubmed publisher
  • immunoprecipitation; mouse; loading ...; fig 1f
  • immunohistochemistry; mouse; loading ...; fig 1b
  • western blot; mouse; loading ...; fig 1f
Chen X, Xin N, Pan Y, Zhu L, Yin P, Liu Q, et al. Huntingtin-Associated Protein 1 in Mouse Hypothalamus Stabilizes Glucocorticoid Receptor in Stress Response. Front Cell Neurosci. 2020;14:125 pubmed publisher
  • western blot; mouse; loading ...; fig 4b
Trusca V, Fuior E, Fenyo I, Kardassis D, Simionescu M, Gafencu A. Differential action of glucocorticoids on apolipoprotein E gene expression in macrophages and hepatocytes. PLoS ONE. 2017;12:e0174078 pubmed publisher
Gazorpak M, Hugentobler K, Paul D, Germain P, Kretschmer M, Ivanova I, et al. Harnessing PROTAC technology to combat stress hormone receptor activation. Nat Commun. 2023;14:8177 pubmed publisher
Ehlers L, Kirchner M, Mertins P, Strehl C, Buttgereit F, Gaber T. The Anti-Glucocorticoid Receptor Antibody Clone 5E4: Raising Awareness of Unspecific Antibody Binding. Int J Mol Sci. 2022;23: pubmed publisher
Vanderhaeghen T, Timmermans S, Watts D, Paakinaho V, Eggermont M, Vandewalle J, et al. Reprogramming of glucocorticoid receptor function by hypoxia. EMBO Rep. 2022;23:e53083 pubmed publisher
Liang L, Gu W, Li M, Gao R, Zhang X, Guo C, et al. The long noncoding RNA HOTAIRM1 controlled by AML1 enhances glucocorticoid resistance by activating RHOA/ROCK1 pathway through suppressing ARHGAP18. Cell Death Dis. 2021;12:702 pubmed publisher
Liu B, Zhou H, Zhang T, Gao X, Tao B, Xing H, et al. Loss of endothelial glucocorticoid receptor promotes angiogenesis via upregulation of Wnt/β-catenin pathway. Angiogenesis. 2021;24:631-645 pubmed publisher
Agnew E, Garcia Burgos A, Richardson R, Manos H, Thomson A, Sooy K, et al. Antenatal dexamethasone treatment transiently alters diastolic function in the mouse fetal heart. J Endocrinol. 2019;241:279-292 pubmed publisher
Mitre Aguilar I, Barrios Garcia T, Ruiz Lopez V, Cabrera Quintero A, Mejía Domínguez N, Ventura Gallegos J, et al. Glucocorticoid-dependent expression of IAP participates in the protection against TNF-mediated cytotoxicity in MCF7 cells. BMC Cancer. 2019;19:356 pubmed publisher
Rollins D, Kharlyngdoh J, Coppo M, Tharmalingam B, Mimouna S, Guo Z, et al. Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages. Nat Commun. 2017;8:1739 pubmed publisher
Sasse S, Zuo Z, Kadiyala V, Zhang L, Pufall M, Jain M, et al. Response Element Composition Governs Correlations between Binding Site Affinity and Transcription in Glucocorticoid Receptor Feed-forward Loops. J Biol Chem. 2015;290:19756-69 pubmed publisher
product information
Catalog Number :
sc-393232
Product Name :
GR (G-5) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
G-5
Isotype :
IgG2b
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
GR
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA