product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Wip1 (F-10) Antibody
catalog :
sc-376257
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
F-10
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 9
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 6b
Sun R, Hedl M, Abraham C. TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants. Cell Mol Gastroenterol Hepatol. 2021;11:249-272 pubmed publisher
  • western blot; human; 1:1000; fig 1b
Fons N, Sundaram R, Breuer G, Peng S, McLean R, Kalathil A, et al. PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma. Nat Commun. 2019;10:3790 pubmed publisher
  • western blot; human; loading ...; fig s2b
Hsu J, Dayaram T, Tovy A, De Braekeleer E, Jeong M, Wang F, et al. PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy. Cell Stem Cell. 2018;23:700-713.e6 pubmed publisher
  • western blot; human; 1:200; loading ...; fig 2a
Esfandiari A, Hawthorne T, Nakjang S, Lunec J. Chemical Inhibition of Wild-Type p53-Induced Phosphatase 1 (WIP1/PPM1D) by GSK2830371 Potentiates the Sensitivity to MDM2 Inhibitors in a p53-Dependent Manner. Mol Cancer Ther. 2016;15:379-91 pubmed publisher
Storchova R, Palek M, Palkova N, Veverka P, Brom T, Hofr C, et al. Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres. Nucleic Acids Res. 2023;51:1154-1172 pubmed publisher
Burocziova M, Burdova K, Martinikova A, Kaspárek P, Kleiblova P, Danielsen S, et al. Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon. Cell Death Dis. 2019;10:818 pubmed publisher
Liu Y, Xu J, Choi H, Han C, Fang Y, Li Y, et al. Targeting 17q23 amplicon to overcome the resistance to anti-HER2 therapy in HER2+ breast cancer. Nat Commun. 2018;9:4718 pubmed publisher
Brazina J, Svadlenka J, Macurek L, Andera L, Hodny Z, Bartek J, et al. DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase. Cell Cycle. 2015;14:375-87 pubmed publisher
Zhang L, Chen L, Wan H, Yang R, Wang Z, Feng J, et al. Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas. Nat Genet. 2014;46:726-30 pubmed publisher
product information
Catalog Number :
sc-376257
Product Name :
Wip1 (F-10) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
F-10
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Wip1
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA