product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
MCT4 (D-1) Antibody
catalog :
sc-376140
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D-1
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1a
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 9e
  • western blot; mouse; loading ...; fig 1a, 9b
Lai S, Lin H, Liu Y, Yang L, Lu D. Monocarboxylate Transporter 4 Regulates Glioblastoma Motility and Monocyte Binding Ability. Cancers (Basel). 2020;12: pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 1b
Bisetto S, Whitaker Menezes D, Wilski N, Tuluc M, Curry J, Zhan T, et al. Monocarboxylate Transporter 4 (MCT4) Knockout Mice Have Attenuated 4NQO Induced Carcinogenesis; A Role for MCT4 in Driving Oral Squamous Cell Cancer. Front Oncol. 2018;8:324 pubmed publisher
  • western blot; human; 1:500; loading ...; fig s16b
Persi E, Duran Frigola M, Damaghi M, Roush W, Aloy P, Cleveland J, et al. Systems analysis of intracellular pH vulnerabilities for cancer therapy. Nat Commun. 2018;9:2997 pubmed publisher
  • western blot; human
Shen C, Chen R, Qian Z, Meng X, Hu T, Li Y, et al. Intestinal absorption mechanisms of MTBH, a novel hesperetin derivative, in Caco-2 cells, and potential involvement of monocarboxylate transporter 1 and multidrug resistance protein 2. Eur J Pharm Sci. 2015;78:214-24 pubmed publisher
Pemovska T, Bigenzahn J, Srndic I, Lercher A, Bergthaler A, César Razquin A, et al. Metabolic drug survey highlights cancer cell dependencies and vulnerabilities. Nat Commun. 2021;12:7190 pubmed publisher
Yu X, Zhang R, Wei C, Gao Y, Yu Y, Wang L, et al. MCT2 overexpression promotes recovery of cognitive function by increasing mitochondrial biogenesis in a rat model of stroke. Anim Cells Syst (Seoul). 2021;25:93-101 pubmed publisher
Wang D, Hartman R, Han C, Zhou C, Couch B, Malkamaki M, et al. Lactate oxidative phosphorylation by annulus fibrosus cells: evidence for lactate-dependent metabolic symbiosis in intervertebral discs. Arthritis Res Ther. 2021;23:145 pubmed publisher
Zhang Y, Le T, Grabau R, Mohseni Z, Kim H, Natale D, et al. TMEM16F phospholipid scramblase mediates trophoblast fusion and placental development. Sci Adv. 2020;6:eaba0310 pubmed publisher
Benjamin D, Robay D, Hindupur S, Pohlmann J, Colombi M, El Shemerly M, et al. Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells. Cell Rep. 2018;25:3047-3058.e4 pubmed publisher
Updegraff B, Zhou X, Guo Y, Padanad M, Chen P, Yang C, et al. Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism. Cell Rep. 2018;25:2223-2233.e6 pubmed publisher
Latif A, Chadwick A, Kitson S, Gregson H, Sivalingam V, Bolton J, et al. Monocarboxylate Transporter 1 (MCT1) is an independent prognostic biomarker in endometrial cancer. BMC Clin Pathol. 2017;17:27 pubmed publisher
Zhu J, Wu Y, Zhang W, Zhang X, Ding X, Li H, et al. Monocarboxylate transporter 4 facilitates cell proliferation and migration and is associated with poor prognosis in oral squamous cell carcinoma patients. PLoS ONE. 2014;9:e87904 pubmed publisher
product information
Catalog Number :
sc-376140
Product Name :
MCT4 (D-1) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
D-1
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
MCT4
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA