product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Slfn11 (E-4) Antibody
catalog :
sc-374339
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
E-4
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation, immunocytochemistry knockout validation
more info or order :
Santa Cruz Biotechnology product webpage
citations: 5
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry knockout validation; human; loading ...; fig s1a,b
  • western blot knockout validation; human; loading ...; fig s2b
Murai J, Feng Y, Yu G, Ru Y, Tang S, Shen Y, et al. Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition. Oncotarget. 2016;7:76534-76550 pubmed publisher
  • immunoprecipitation; human; fig 3
  • western blot; human; fig 3
Nogales V, Reinhold W, Varma S, Martinez Cardus A, Moutinho C, Moran S, et al. Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs. Oncotarget. 2016;7:3084-97 pubmed publisher
Waters T, Goss K, Koppenhafer S, Terry W, Gordon D. Eltrombopag inhibits the proliferation of Ewing sarcoma cells via iron chelation and impaired DNA replication. BMC Cancer. 2020;20:1171 pubmed publisher
Lok B, Gardner E, Schneeberger V, Ni A, Desmeules P, Rekhtman N, et al. PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer. Clin Cancer Res. 2017;23:523-535 pubmed publisher
Abdel Mohsen M, Raposo R, Deng X, Li M, Liegler T, Sinclair E, et al. Expression profile of host restriction factors in HIV-1 elite controllers. Retrovirology. 2013;10:106 pubmed publisher
product information
Catalog Number :
sc-374339
Product Name :
Slfn11 (E-4) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
E-4
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Slfn11
Specificity :
human
Uses :
WB, IP, IF, IHC(P), ELISA
more info or order :
Santa Cruz Biotechnology product webpage
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA