product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
TREM-2 (B-3) Antibody
catalog :
sc-373828
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-3
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section
citations: 5
Published Application/Species/Sample/DilutionReference
  • ELISA; human; 1 ug/ml; fig 3f
Reifschneider A, Robinson S, van Lengerich B, Gnörich J, Logan T, Heindl S, et al. Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency. EMBO J. 2022;41:e109108 pubmed publisher
  • immunohistochemistry - frozen section; human; loading ...; fig 5c
Zhong L, Chen X, Wang T, Wang Z, Liao C, Wang Z, et al. Soluble TREM2 induces inflammatory responses and enhances microglial survival. J Exp Med. 2017;214:597-607 pubmed publisher
  • western blot; human; fig 1
Bhattacharjee S, Zhao Y, Dua P, Rogaev E, Lukiw W. microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration. PLoS ONE. 2016;11:e0150211 pubmed publisher
Suarez Calvet M, Capell A, Araque Caballero M, Morenas Rodríguez E, Fellerer K, Franzmeier N, et al. CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline. EMBO Mol Med. 2018;10: pubmed publisher
Woollacott I, Nicholas J, Heslegrave A, Heller C, Foiani M, Dick K, et al. Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup. Alzheimers Res Ther. 2018;10:79 pubmed publisher
product information
Catalog Number :
sc-373828
Product Name :
TREM-2 (B-3) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
B-3
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
TREM-2
Specificity :
human
Uses :
WB, IP, IF, ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA