Published Application/Species/Sample/Dilution | Reference |
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- immunocytochemistry knockout validation; mouse; 1:100; loading ...; fig s1f
- immunohistochemistry knockout validation; mouse; 1:100; loading ...; fig s1e
- western blot knockout validation; mouse; 1:100; loading ...; fig s1d
| Wu Y, Dong J, Feng S, Zhao Q, Duan P, Xiong M, et al. Maternal UHRF1 Is Essential for Transcription Landscapes and Repression of Repetitive Elements During the Maternal-to-Zygotic Transition. Front Cell Dev Biol. 2020;8:610773 pubmed publisher
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- western blot knockout validation; human; loading ...; fig s4k
- immunohistochemistry - paraffin section; human; loading ...; fig 1a
- chromatin immunoprecipitation; human; loading ...; fig 4g
- western blot; mouse; fig 1c
| Zhang J, Zhang H, Ding X, Hu J, Li Y, Zhang J, et al. Crosstalk between macrophage-derived PGE2 and tumor UHRF1 drives hepatocellular carcinoma progression. Theranostics. 2022;12:3776-3793 pubmed publisher
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- western blot; mouse; 1:500; loading ...; fig 2c
| Aibara D, Takahashi S, Yagai T, Kim D, Brocker C, Levi M, et al. Gene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation. iScience. 2022;25:104196 pubmed publisher
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- western blot; human; 1:100; loading ...; fig 3m
| Zheng T, Liu X, Li X, Wang Q, Zhao Y, Li X, et al. Dickkopf-1 promotes Vascular Smooth Muscle Cell proliferation and migration through upregulating UHRF1 during Cyclic Stretch application. Int J Biol Sci. 2021;17:1234-1249 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig s2a
| Lopez Martinez D, Kupculak M, Yang D, Yoshikawa Y, Liang C, Wu R, et al. Phosphorylation of FANCD2 Inhibits the FANCD2/FANCI Complex and Suppresses the Fanconi Anemia Pathway in the Absence of DNA Damage. Cell Rep. 2019;27:2990-3005.e5 pubmed publisher
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- western blot; mouse; loading ...; fig 1c
| Liu Y, Zhang B, Meng X, Korn M, Parent J, Lu L, et al. UHRF2 regulates local 5-methylcytosine and suppresses spontaneous seizures. Epigenetics. 2017;12:551-560 pubmed publisher
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- western blot; human; 1:1000; fig s5
| Liang C, Li Z, Lopez Martinez D, Nicholson W, Venien Bryan C, Cohn M. The FANCD2-FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2. Nat Commun. 2016;7:12124 pubmed publisher
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- western blot; human; loading ...; fig 6b
| Liu Y, Zhang B, Kuang H, Korakavi G, Lu L, Yu X. Zinc Finger Protein 618 Regulates the Function of UHRF2 (Ubiquitin-like with PHD and Ring Finger Domains 2) as a Specific 5-Hydroxymethylcytosine Reader. J Biol Chem. 2016;291:13679-88 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:100
| Kim K, Son H, Choi S, Hahm J, Jung H, Baek H, et al. H3K9 methyltransferase G9a negatively regulates UHRF1 transcription during leukemia cell differentiation. Nucleic Acids Res. 2015;43:3509-23 pubmed publisher
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| Haggerty C, Kretzmer H, Riemenschneider C, Kumar A, Mattei A, Bailly N, et al. Dnmt1 has de novo activity targeted to transposable elements. Nat Struct Mol Biol. 2021;28:594-603 pubmed publisher
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| Liu K, Wang Y, Zhu Q, Li P, Chen J, Tang Z, et al. Aberrantly expressed HORMAD1 disrupts nuclear localization of MCM8-MCM9 complex and compromises DNA mismatch repair in cancer cells. Cell Death Dis. 2020;11:519 pubmed publisher
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| Foster B, Stolz P, Mulholland C, Montoya A, Kramer H, Bultmann S, et al. Critical Role of the UBL Domain in Stimulating the E3 Ubiquitin Ligase Activity of UHRF1 toward Chromatin. Mol Cell. 2018;72:739-752.e9 pubmed publisher
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| Li T, Wang L, Du Y, Xie S, Yang X, Lian F, et al. Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation. Nucleic Acids Res. 2018;46:3218-3231 pubmed publisher
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| Turnbull A, Ioannidis S, Krajewski W, Pinto Fernandez A, Heride C, Martin A, et al. Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Nature. 2017;550:481-486 pubmed publisher
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| Kan G, He H, Zhao Q, Li X, Li M, Yang H, et al. Functional dissection of the role of UHRF1 in the regulation of retinoblastoma methylome. Oncotarget. 2017;8:39497-39511 pubmed publisher
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| Wang K, Chen C, Tsai S, Shen C. Epigenetic Enhancement of the Post-replicative DNA Mismatch Repair of Mammalian Genomes by a Hemi-mCpG-Np95-Dnmt1 Axis. Sci Rep. 2016;6:37490 pubmed publisher
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| Benavente C, Finkelstein D, Johnson D, Marine J, Ashery Padan R, Dyer M. Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression. Oncotarget. 2014;5:9594-608 pubmed
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