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company name :
Santa Cruz Biotechnology
product type :
gene knockdown
product name :
Nrf2 siRNA (h)
catalog :
sc-37030
quantity :
10 µM
price :
293 USD
citations: 21
Reference
Vierbuchen T, Agarwal S, Johnson J, Galia L, Lei X, Stein K, et al. The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2. Proc Natl Acad Sci U S A. 2023;120:e2213715120 pubmed publisher
Han B, Wang K, Tu Y, Tan L, He C. Low-Dose Berberine Attenuates the Anti-Breast Cancer Activity of Chemotherapeutic Agents via Induction of Autophagy and Antioxidation. Dose Response. 2020;18:1559325820939751 pubmed publisher
Fassmannová D, Sedlák F, Sedlacek J, Spicka I, Grantz Sasková K. Nelfinavir Inhibits the TCF11/Nrf1-Mediated Proteasome Recovery Pathway in Multiple Myeloma. Cancers (Basel). 2020;12: pubmed publisher
Chen C, Chen W, Hung C, Lin T, Lee M, Chen I, et al. Shaoyao Gancao Tang (SG-Tang), a formulated Chinese medicine, reduces aggregation and exerts neuroprotection in spinocerebellar ataxia type 17 (SCA17) cell and mouse models. Aging (Albany NY). 2019;11:986-1007 pubmed publisher
Khamari R, Trinh A, Gabert P, Corazao Rozas P, Riveros Cruz S, Balayssac S, et al. Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors. Cell Death Dis. 2018;9:325 pubmed publisher
Jiang X, Bao Y, Liu H, Kou X, Zhang Z, Sun F, et al. VPS34 stimulation of p62 phosphorylation for cancer progression. Oncogene. 2017;36:6850-6862 pubmed publisher
Choi H, Kim H, Park J, Kim I, Bae E, Ma S, et al. PGC-1α attenuates hydrogen peroxide-induced apoptotic cell death by upregulating Nrf-2 via GSK3β inactivation mediated by activated p38 in HK-2 Cells. Sci Rep. 2017;7:4319 pubmed publisher
Huang H, Falgout B, Takeda K, Yamada K, Dhawan S. Nrf2-dependent induction of innate host defense via heme oxygenase-1 inhibits Zika virus replication. Virology. 2017;503:1-5 pubmed publisher
Olagnier D, Peri S, Steel C, van Montfoort N, Chiang C, Beljanski V, et al. Cellular oxidative stress response controls the antiviral and apoptotic programs in dengue virus-infected dendritic cells. PLoS Pathog. 2014;10:e1004566 pubmed publisher
Martin D, Li Y, Yang J, Wang G, Margariti A, Jiang Z, et al. Unspliced X-box-binding protein 1 (XBP1) protects endothelial cells from oxidative stress through interaction with histone deacetylase 3. J Biol Chem. 2014;289:30625-34 pubmed publisher
Li J, Gao Y, Chu S, Zhang Z, Xia C, Mou Z, et al. Nrf2 pathway activation contributes to anti-fibrosis effects of ginsenoside Rg1 in a rat model of alcohol- and CCl4-induced hepatic fibrosis. Acta Pharmacol Sin. 2014;35:1031-44 pubmed publisher
Hsu Y, Tseng Y, Lo Y. Berberine, a natural antidiabetes drug, attenuates glucose neurotoxicity and promotes Nrf2-related neurite outgrowth. Toxicol Appl Pharmacol. 2013;272:787-96 pubmed publisher
Lisk C, McCord J, Bose S, Sullivan T, Loomis Z, Nozik Grayck E, et al. Nrf2 activation: a potential strategy for the prevention of acute mountain sickness. Free Radic Biol Med. 2013;63:264-73 pubmed publisher
Ravuri C, Svineng G, Huseby N. Differential regulation of ?-glutamyltransferase and glutamate cysteine ligase expression after mitochondrial uncoupling: ?-glutamyltransferase is regulated in an Nrf2- and NF?B-independent manner. Free Radic Res. 2013;47:394-403 pubmed publisher
Bae J, Lee D, Kim Y, Gil M, Lee J, Lee K. Berberine protects 6-hydroxydopamine-induced human dopaminergic neuronal cell death through the induction of heme oxygenase-1. Mol Cells. 2013;35:151-7 pubmed publisher
Lee S, Yang H, Jeong S, Jin Y, Park C, Park Y. Induction of heme oxygenase-1 inhibits cell death in crotonaldehyde-stimulated HepG2 cells via the PKC-?-p38-Nrf2 pathway. PLoS ONE. 2012;7:e41676 pubmed publisher
Emmert S, El Bayoumy K, Das A, Sun Y, Amin S, Desai D, et al. Induction of lung glutathione and glutamylcysteine ligase by 1,4-phenylenebis(methylene)selenocyanate and its glutathione conjugate: role of nuclear factor-erythroid 2-related factor 2. Free Radic Biol Med. 2012;52:2064-71 pubmed publisher
Achuthan S, Santhoshkumar T, Prabhakar J, Nair S, Pillai M. Drug-induced senescence generates chemoresistant stemlike cells with low reactive oxygen species. J Biol Chem. 2011;286:37813-29 pubmed publisher
Kundu R, Dasgupta S, Biswas A, Bhattacharya S, Pal B, Bhattacharya S, et al. Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression. Biochem Pharmacol. 2011;82:1186-97 pubmed publisher
Seng S, Avraham H, Birrane G, Jiang S, Avraham S. Nuclear matrix protein (NRP/B) modulates the nuclear factor (Erythroid-derived 2)-related 2 (NRF2)-dependent oxidative stress response. J Biol Chem. 2010;285:26190-8 pubmed publisher
Fledderus J, Boon R, Volger O, Hurttila H, Yla Herttuala S, Pannekoek H, et al. KLF2 primes the antioxidant transcription factor Nrf2 for activation in endothelial cells. Arterioscler Thromb Vasc Biol. 2008;28:1339-46 pubmed publisher
product information
Catalog Number :
sc-37030
Product Name :
Nrf2 siRNA (h)
Product Type :
siRNA
Size :
10 µM
List Price :
293 USD
Immunogen :
Nrf2
Specificity :
human
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA