product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Nrf2 (A-10) Antibody
catalog :
sc-365949
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A-10
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 34
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3a
Wrublewsky S, Glas J, Carlein C, Nalbach L, Hoffmann M, Pack M, et al. The loss of pancreatic islet NADPH oxidase (NOX)2 improves islet transplantation. Redox Biol. 2022;55:102419 pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig 5a
Wang L, Lavier J, Hua W, Wang Y, Gong L, Wei H, et al. High-Intensity Interval Training and Moderate-Intensity Continuous Training Attenuate Oxidative Damage and Promote Myokine Response in the Skeletal Muscle of ApoE KO Mice on High-Fat Diet. Antioxidants (Basel). 2021;10: pubmed publisher
  • immunocytochemistry; human; 1:50; loading ...; fig 4a
Cores A, Abril S, Michalska P, Duarte P, Olives A, Martín M, et al. Bisavenathramide Analogues as Nrf2 Inductors and Neuroprotectors in In Vitro Models of Oxidative Stress and Hyperphosphorylation. Antioxidants (Basel). 2021;10: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2f
Choi E, Jeong J, Jang H, Ahn Y, Kim K, An H, et al. Skeletal Lipocalin-2 Is Associated with Iron-Related Oxidative Stress in ob/ob Mice with Sarcopenia. Antioxidants (Basel). 2021;10: pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 5d
  • western blot; mouse; 1:1000; loading ...; fig 5a
Chung L, Liu S, Huang S, Salter D, Lee H, Hsu Y. High phosphate induces skeletal muscle atrophy and suppresses myogenic differentiation by increasing oxidative stress and activating Nrf2 signaling. Aging (Albany NY). 2020;12:21446-21468 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 6b
  • western blot; human; loading ...; fig 6a
Molagoda I, Lee K, Choi Y, Kim G. Anthocyanins from Hibiscus syriacus L. Inhibit Oxidative Stress-Mediated Apoptosis by Activating the Nrf2/HO-1 Signaling Pathway. Antioxidants (Basel). 2020;9: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 8c
  • western blot; mouse; 1:1000; loading ...; fig 8a
Yuan Z, Yang L, Zhang X, Ji P, Hua Y, Wei Y. Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-κB and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier Function. Front Pharmacol. 2019;10:1354 pubmed publisher
  • western blot; human; loading ...; fig s10
Li J, Yakushi T, Parlati F, MacKinnon A, Pérez C, Ma Y, et al. Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11. Nat Chem Biol. 2017;13:486-493 pubmed publisher
  • western blot; mouse; 1:1500; loading ...; fig 8a
Duan W, Chen J, Wu Y, Zhang Y, Xu Y. Protective effect of higenamine ameliorates collagen-induced arthritis through heme oxygenase-1 and PI3K/Akt/Nrf-2 signaling pathways. Exp Ther Med. 2016;12:3107-3112 pubmed
  • western blot; rat; loading ...; fig 7a
Yang W, Yang Y, Yang J, Liang M, Song J. Treatment with bone marrow mesenchymal stem cells combined with plumbagin alleviates spinal cord injury by affecting oxidative stress, inflammation, apoptotis and the activation of the Nrf2 pathway. Int J Mol Med. 2016;37:1075-82 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig 2
  • western blot; human; 1:500; fig 1
Kawasaki Y, Ishigami S, Arigami T, Uenosono Y, Yanagita S, Uchikado Y, et al. Clinicopathological significance of nuclear factor (erythroid-2)-related factor 2 (Nrf2) expression in gastric cancer. BMC Cancer. 2015;15:5 pubmed publisher
  • western blot; human
Ishaq M, Evans M, Ostrikov K. Atmospheric pressure gas plasma-induced colorectal cancer cell death is mediated by Nox2-ASK1 apoptosis pathways and oxidative stress is mitigated by Srx-Nrf2 anti-oxidant system. Biochim Biophys Acta. 2014;1843:2827-37 pubmed publisher
  • immunocytochemistry; human
  • western blot; human; 1:1000
Ramyaa P, Krishnaswamy R, Padma V. Quercetin modulates OTA-induced oxidative stress and redox signalling in HepG2 cells - up regulation of Nrf2 expression and down regulation of NF-?B and COX-2. Biochim Biophys Acta. 2014;1840:681-92 pubmed publisher
Beltzig L, Schwarzenbach C, Leukel P, Frauenknecht K, Sommer C, Tancredi A, et al. Senescence Is the Main Trait Induced by Temozolomide in Glioblastoma Cells. Cancers (Basel). 2022;14: pubmed publisher
Polat I, Tarrado Castellarnau M, Benito A, Hernandez Carro C, Centelles J, Marin S, et al. Glutamine Modulates Expression and Function of Glucose 6-Phosphate Dehydrogenase via NRF2 in Colon Cancer Cells. Antioxidants (Basel). 2021;10: pubmed publisher
Lee S, Jee S, Kim M, Kim S, Shin M, Kim Y, et al. Curcumin Suppresses the Lipid Accumulation and Oxidative Stress Induced by Benzo[a]pyrene Toxicity in HepG2 Cells. Antioxidants (Basel). 2021;10: pubmed publisher
Giudetti A, Vergara D, Longo S, Friuli M, Eramo B, Tacconi S, et al. Oleoylethanolamide Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in High-Fat Diet-Fed Rats. Antioxidants (Basel). 2021;10: pubmed publisher
D Amico R, Trovato Salinaro A, Cordaro M, Fusco R, Impellizzeri D, Interdonato L, et al. Hidrox® and Chronic Cystitis: Biochemical Evaluation of Inflammation, Oxidative Stress, and Pain. Antioxidants (Basel). 2021;10: pubmed publisher
D Amico R, Genovese T, Cordaro M, Siracusa R, Gugliandolo E, Peritore A, et al. Palmitoylethanolamide/Baicalein Regulates the Androgen Receptor Signaling and NF-κB/Nrf2 Pathways in Benign Prostatic Hyperplasia. Antioxidants (Basel). 2021;10: pubmed publisher
Potteti H, Venkareddy L, Noone P, Ankireddy A, Tamatam C, Mehta D, et al. Nrf2 Regulates Anti-Inflammatory A20 Deubiquitinase Induction by LPS in Macrophages in Contextual Manner. Antioxidants (Basel). 2021;10: pubmed publisher
Fusco R, Salinaro A, Siracusa R, D Amico R, Impellizzeri D, Scuto M, et al. Hidrox® Counteracts Cyclophosphamide-Induced Male Infertility through NRF2 Pathways in a Mouse Model. Antioxidants (Basel). 2021;10: pubmed publisher
Cordaro M, Trovato Salinaro A, Siracusa R, D Amico R, Impellizzeri D, Scuto M, et al. Hidrox® and Endometriosis: Biochemical Evaluation of Oxidative Stress and Pain. Antioxidants (Basel). 2021;10: pubmed publisher
Yan J, Huang J, Liu A, Wu J, Fan H, Shen M, et al. Atorvastatin improves motor function, anxiety and depression by NOX2-mediated autophagy and oxidative stress in MPTP-lesioned mice. Aging (Albany NY). 2020;13:831-845 pubmed publisher
Cordaro M, Fusco R, D Amico R, Siracusa R, Peritore A, Gugliandolo E, et al. Cashew (Anacardium occidentale L.) Nuts Modulate the Nrf2 and NLRP3 Pathways in Pancreas and Lung after Induction of Acute Pancreatitis by Cerulein. Antioxidants (Basel). 2020;9: pubmed publisher
Lanza M, Casili G, Torre G, Giuffrida D, Rotondo A, Esposito E, et al. Properties of a New Food Supplement Containing Actinia equina Extract. Antioxidants (Basel). 2020;9: pubmed publisher
Cai E, Ishikawa Y, Zhang W, Leite N, Li J, Hou S, et al. Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes. Nat Metab. 2020;2:934-945 pubmed publisher
Do M, Lee J, Ahn J, Hong M, Kim J, Kim S. Isosamidin from Peucedanum japonicum Roots Prevents Methylglyoxal-Induced Glucotoxicity in Human Umbilical Vein Endothelial Cells via Suppression of ROS-Mediated Bax/Bcl-2. Antioxidants (Basel). 2020;9: pubmed publisher
Chen C, Lin C, Wu Y, Yen C, Huang Y, Lin J, et al. Lactulose and Melibiose Inhibit α-Synuclein Aggregation and Up-Regulate Autophagy to Reduce Neuronal Vulnerability. Cells. 2020;9: pubmed publisher
Chazarin B, Ziemianin A, Evans A, Meugnier E, Loizon E, Chery I, et al. Limited Oxidative Stress Favors Resistance to Skeletal Muscle Atrophy in Hibernating Brown Bears (Ursus Arctos). Antioxidants (Basel). 2019;8: pubmed publisher
Marcheggiani F, Cirilli I, Orlando P, Silvestri S, Vogelsang A, Knott A, et al. Modulation of Coenzyme Q10 content and oxidative status in human dermal fibroblasts using HMG-CoA reductase inhibitor over a broad range of concentrations. From mitohormesis to mitochondrial dysfunction and accelerated aging. Aging (Albany NY). 2019;11:2565-2582 pubmed publisher
Ji W, Wang L, He S, Yan L, Li T, Wang J, et al. Effects of acute hypoxia exposure with different durations on activation of Nrf2-ARE pathway in mouse skeletal muscle. PLoS ONE. 2018;13:e0208474 pubmed publisher
Wu L, Pan C, Wei X, Shi Y, Zheng J, Lin X, et al. lncRNA KRAL reverses 5-fluorouracil resistance in hepatocellular carcinoma cells by acting as a ceRNA against miR-141. Cell Commun Signal. 2018;16:47 pubmed publisher
Lin G, Luo D, Liu J, Wu X, Chen J, Huang Q, et al. Hepatoprotective Effect of Polysaccharides Isolated from Dendrobium officinale against Acetaminophen-Induced Liver Injury in Mice via Regulation of the Nrf2-Keap1 Signaling Pathway. Oxid Med Cell Longev. 2018;2018:6962439 pubmed publisher
Salanova M, Schiffl G, Gutsmann M, Felsenberg D, Furlan S, Volpe P, et al. Nitrosative stress in human skeletal muscle attenuated by exercise countermeasure after chronic disuse. Redox Biol. 2013;1:514-26 pubmed publisher
product information
Catalog Number :
sc-365949
Product Name :
Nrf2 (A-10) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
A-10
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Nrf2
Specificity :
human
Uses :
WB, IP, IF, ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA