product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Keap1 (G-2) Antibody
catalog :
sc-365626
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G-2
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, western blot knockout validation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig 1c
Koppula P, Olszewski K, Zhang Y, Kondiparthi L, Liu X, Lei G, et al. KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition. iScience. 2021;24:102649 pubmed publisher
  • western blot knockout validation; human; 1:500; loading ...; fig 5a
Cao J, Poddar A, Magtanong L, Lumb J, Mileur T, Reid M, et al. A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity. Cell Rep. 2019;26:1544-1556.e8 pubmed publisher
  • immunoprecipitation; human; 1:200; loading ...; fig 2d
Zhu Y, Zhang Y, Huang X, Xie Y, Qu Y, Long H, et al. Z-Ligustilide protects vascular endothelial cells from oxidative stress and rescues high fat diet-induced atherosclerosis by activating multiple NRF2 downstream genes. Atherosclerosis. 2019;284:110-120 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1a
Skowron M, Niegisch G, Albrecht P, Van Koeveringe G, Romano A, Albers P, et al. Various Mechanisms Involve the Nuclear Factor (Erythroid-Derived 2)-Like (NRF2) to Achieve Cytoprotection in Long-Term Cisplatin-Treated Urothelial Carcinoma Cell Lines. Int J Mol Sci. 2017;18: pubmed publisher
  • western blot; human; 1:300-500
Sajja R, Green K, Cucullo L. Altered Nrf2 signaling mediates hypoglycemia-induced blood-brain barrier endothelial dysfunction in vitro. PLoS ONE. 2015;10:e0122358 pubmed publisher
Ghosh A, Su Y, Forman M, Keyes R, Smith B, Hu X, et al. Harnessing the Noncanonical Keap1-Nrf2 Pathway for Human Cytomegalovirus Control. J Virol. 2023;97:e0016023 pubmed publisher
Hwang J, Kim W, Cho Y, Ryu J, Choi J, Jeong S, et al. Chloroquine reverses chemoresistance via upregulation of p21WAF1/CIP1 and autophagy inhibition in ovarian cancer. Cell Death Dis. 2020;11:1034 pubmed publisher
Ahn Y, Lim J, Kim H. Docosahexaenoic Acid Induces Expression of NAD(P)H: Quinone Oxidoreductase and Heme Oxygenase-1 through Activation of Nrf2 in Cerulein-Stimulated Pancreatic Acinar Cells. Antioxidants (Basel). 2020;9: pubmed publisher
Lei G, Zhang Y, Koppula P, Liu X, Zhang J, Lin S, et al. The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression. Cell Res. 2020;30:146-162 pubmed publisher
Lin G, Luo D, Liu J, Wu X, Chen J, Huang Q, et al. Hepatoprotective Effect of Polysaccharides Isolated from Dendrobium officinale against Acetaminophen-Induced Liver Injury in Mice via Regulation of the Nrf2-Keap1 Signaling Pathway. Oxid Med Cell Longev. 2018;2018:6962439 pubmed publisher
Liu X, Lin X, Zhang S, Guo C, Li J, Mi Y, et al. Lycopene ameliorates oxidative stress in the aging chicken ovary via activation of Nrf2/HO-1 pathway. Aging (Albany NY). 2018;10:2016-2036 pubmed publisher
Jarolim K, Del Favero G, Pahlke G, Dostal V, Zimmermann K, Heiss E, et al. Activation of the Nrf2-ARE pathway by the Alternaria alternata mycotoxins altertoxin I and II. Arch Toxicol. 2017;91:203-216 pubmed publisher
Li B, Kim D, Yadav R, Kim H, Chae H. Sulforaphane prevents doxorubicin-induced oxidative stress and cell death in rat H9c2 cells. Int J Mol Med. 2015;36:53-64 pubmed publisher
product information
Catalog Number :
sc-365626
Product Name :
Keap1 (G-2) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
G-2
Isotype :
IgG2b
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Keap1
Specificity :
human
Uses :
WB, IP, IF, ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA