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company name :
Santa Cruz Biotechnology
product type :
gene knockdown
product name :
HIF-1α siRNA (h)
catalog :
sc-35561
quantity :
10 µM
price :
293 USD
citations: 19
Reference
Sil S, Singh S, Chemparathy D, Chivero E, Gordon L, Buch S. Astrocytes & Astrocyte derived Extracellular Vesicles in Morphine Induced Amyloidopathy: Implications for Cognitive Deficits in Opiate Abusers. Aging Dis. 2021;12:1389-1408 pubmed publisher
Cortés E, Lachowski D, Robinson B, Sarper M, Teppo J, Thorpe S, et al. Tamoxifen mechanically reprograms the tumor microenvironment via HIF-1A and reduces cancer cell survival. EMBO Rep. 2019;20: pubmed publisher
Labrousse Arias D, Martínez Alonso E, Corral Escariz M, Bienes Martínez R, Berridy J, Serrano Oviedo L, et al. VHL promotes immune response against renal cell carcinoma via NF-κB-dependent regulation of VCAM-1. J Cell Biol. 2017;216:835-847 pubmed publisher
Lv Y, Zhao S, Han J, Zheng L, Yang Z, Zhao L. Hypoxia-inducible factor-1α induces multidrug resistance protein in colon cancer. Onco Targets Ther. 2015;8:1941-8 pubmed publisher
Cursons J, Leuchowius K, Waltham M, Tomaskovic Crook E, Foroutan M, Bracken C, et al. Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines. Cell Commun Signal. 2015;13:26 pubmed publisher
Otake S, Yoshida K, Seira N, Sanchez C, Regan J, Fujino H, et al. Cellular density-dependent down-regulation of EP4 prostanoid receptors via the up-regulation of hypoxia-inducible factor-1α in HCA-7 human colon cancer cells. Pharmacol Res Perspect. 2015;3:e00083 pubmed publisher
Bigot N, Guérillon C, Loisel S, Bertheuil N, Sensebé L, Tarte K, et al. ING1b negatively regulates HIF1α protein levels in adipose-derived stromal cells by a SUMOylation-dependent mechanism. Cell Death Dis. 2015;6:e1612 pubmed publisher
Carrera S, Senra J, Acosta M, Althubiti M, Hammond E, De Verdier P, et al. The role of the HIF-1? transcription factor in increased cell division at physiological oxygen tensions. PLoS ONE. 2014;9:e97938 pubmed publisher
Sen A, Ren S, Lerchenmüller C, Sun J, Weiss N, Most P, et al. MicroRNA-138 regulates hypoxia-induced endothelial cell dysfunction by targeting S100A1. PLoS ONE. 2013;8:e78684 pubmed publisher
Fiaschi T, Giannoni E, Taddei M, Cirri P, Marini A, Pintus G, et al. Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells. Cell Cycle. 2013;12:1791-801 pubmed publisher
Samarajeewa N, Yang F, Docanto M, Sakurai M, McNamara K, Sasano H, et al. HIF-1? stimulates aromatase expression driven by prostaglandin E2 in breast adipose stroma. Breast Cancer Res. 2013;15:R30 pubmed publisher
Mandl M, Kapeller B, Lieber R, Macfelda K. Hypoxia-inducible factor-1? (HIF-1?) is upregulated in a HIF-1?-dependent manner in 518A2 human melanoma cells under hypoxic conditions. Biochem Biophys Res Commun. 2013;434:166-72 pubmed publisher
Liang Y, Zheng T, Song R, Wang J, Yin D, Wang L, et al. Hypoxia-mediated sorafenib resistance can be overcome by EF24 through Von Hippel-Lindau tumor suppressor-dependent HIF-1? inhibition in hepatocellular carcinoma. Hepatology. 2013;57:1847-57 pubmed publisher
Fiaschi T, Marini A, Giannoni E, Taddei M, Gandellini P, De Donatis A, et al. Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay. Cancer Res. 2012;72:5130-40 pubmed publisher
Kim Y, Lee H, Kim T, Eisinger Mathason T, Zhang A, Schmidt B, et al. Overcoming evasive resistance from vascular endothelial growth factor a inhibition in sarcomas by genetic or pharmacologic targeting of hypoxia-inducible factor 1?. Int J Cancer. 2013;132:29-41 pubmed publisher
Doublier S, Belisario D, Polimeni M, Annaratone L, Riganti C, Allia E, et al. HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast. BMC Cancer. 2012;12:4 pubmed publisher
Chung L, Tsui K, Feng T, Lee S, Chang P, Juang H. L-Mimosine blocks cell proliferation via upregulation of B-cell translocation gene 2 and N-myc downstream regulated gene 1 in prostate carcinoma cells. Am J Physiol Cell Physiol. 2012;302:C676-85 pubmed publisher
Zawacka Pankau J, Grinkevich V, Hünten S, Nikulenkov F, Gluch A, Li H, et al. Inhibition of glycolytic enzymes mediated by pharmacologically activated p53: targeting Warburg effect to fight cancer. J Biol Chem. 2011;286:41600-15 pubmed publisher
Lu H, Kao S, Liu T, Liu S, Huang W, Chang K, et al. Areca nut extract induced oxidative stress and upregulated hypoxia inducing factor leading to autophagy in oral cancer cells. Autophagy. 2010;6:725-37 pubmed
product information
Catalog Number :
sc-35561
Product Name :
HIF-1α siRNA (h)
Product Type :
siRNA
Size :
10 µM
List Price :
293 USD
Immunogen :
HIF-1alpha
Specificity :
human
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA