product summary
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company name :
Santa Cruz Biotechnology
product type :
gene knockdown
product name :
GSK-3β siRNA (h)
catalog :
sc-35527
quantity :
10 µM
price :
293 USD
citations: 15
Reference
Mishra M, Thacker G, Sharma A, Singh A, Upadhyay V, Sanyal S, et al. FBW7 Inhibits Myeloid Differentiation in Acute Myeloid Leukemia via GSK3-Dependent Ubiquitination of PU.1. Mol Cancer Res. 2021;19:261-273 pubmed publisher
Li L, Lin L, Li M, Li W. Gilteritinib induces PUMA-dependent apoptotic cell death via AKT/GSK-3β/NF-κB pathway in colorectal cancer cells. J Cell Mol Med. 2020;24:2308-2318 pubmed publisher
Yang S, Zhang X, Qu H, Qu B, Yin X, Zhao H. Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway. Cancer Gene Ther. 2019;: pubmed publisher
Luo L, Liu H, Xi Q. Trastuzumab induces PUMA-dependent apoptosis and inhibits tumor growth in gastric cancer. FEBS Open Bio. 2018;8:1911-1919 pubmed publisher
Xu Q, Tu J, Dou C, Zhang J, Yang L, Liu X, et al. HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma. Mol Cancer. 2017;16:178 pubmed publisher
Maiti S, Mondal S, Satyavarapu E, Mandal C. mTORC2 regulates hedgehog pathway activity by promoting stability to Gli2 protein and its nuclear translocation. Cell Death Dis. 2017;8:e2926 pubmed publisher
Tong J, Wang P, Tan S, Chen D, Nikolovska Coleska Z, Zou F, et al. Mcl-1 Degradation Is Required for Targeted Therapeutics to Eradicate Colon Cancer Cells. Cancer Res. 2017;77:2512-2521 pubmed publisher
Yang S, Zhu Z, Zhang X, Zhang N, Yao Z. Idelalisib induces PUMA-dependent apoptosis in colon cancer cells. Oncotarget. 2017;8:6102-6113 pubmed publisher
Polimeni M, Gulino G, Gazzano E, Kopecka J, Marucco A, Fenoglio I, et al. Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-?-mediated Akt/GSK-3?/SNAIL-1 signalling pathway. Part Fibre Toxicol. 2016;13:27 pubmed publisher
Xuan W, Zhao H, Hankin J, Chen L, Yao S, Ma D. Local anesthetic bupivacaine induced ovarian and prostate cancer apoptotic cell death and underlying mechanisms in vitro. Sci Rep. 2016;6:26277 pubmed publisher
Fu Y, Wang X, Cheng X, Ye F, Xie X, Lu W. Clinicopathological and biological significance of aberrant activation of glycogen synthase kinase-3 in ovarian cancer. Onco Targets Ther. 2014;7:1159-68 pubmed publisher
Dudgeon C, Peng R, Wang P, Sebastiani A, Yu J, Zhang L. Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3? and NF-?B to suppress tumor cell growth. Oncogene. 2012;31:4848-58 pubmed publisher
Chen K, Yuan R, Hu C, Hsu C. Amyloid-? peptide alteration of tau exon-10 splicing via the GSK3?-SC35 pathway. Neurobiol Dis. 2010;40:378-85 pubmed publisher
Tsai C, Kai J, Huang W, Wang C, Wang Y, Chen C, et al. Glycogen synthase kinase-3beta facilitates IFN-gamma-induced STAT1 activation by regulating Src homology-2 domain-containing phosphatase 2. J Immunol. 2009;183:856-64 pubmed publisher
Yang Z, Li J. Stimulation of endothelin-1 gene expression by insulin via phosphoinositide-3 kinase-glycogen synthase kinase-3beta signaling in endothelial cells. Life Sci. 2008;82:512-8 pubmed publisher
product information
Catalog Number :
sc-35527
Product Name :
GSK-3β siRNA (h)
Product Type :
siRNA
Size :
10 µM
List Price :
293 USD
Immunogen :
GSK-3b
Specificity :
human
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA