product summary
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company name :
Santa Cruz Biotechnology
product type :
gene knockdown
product name :
ATF-4 siRNA (h)
catalog :
sc-35112
quantity :
10 µM
price :
293 USD
citations: 8
Reference
Lee D, Kim I, Lee H, Seo M, Cho M, Lee H, et al. Akt enhances the vulnerability of cancer cells to VCP/p97 inhibition-mediated paraptosis. Cell Death Dis. 2024;15:48 pubmed publisher
Jang S, Hong S, Lee D, Kim J, Kim J, Ye S, et al. Inhibition of mTORC1 through ATF4-induced REDD1 and Sestrin2 expression by Metformin. BMC Cancer. 2021;21:803 pubmed publisher
Sarcinelli C, Dragic H, Piecyk M, Barbet V, Duret C, Barthelaix A, et al. ATF4-Dependent NRF2 Transcriptional Regulation Promotes Antioxidant Protection during Endoplasmic Reticulum Stress. Cancers (Basel). 2020;12: pubmed publisher
Cheng C, Qi Y, Wang Y, Chi K, Chung Y, Ouyang C, et al. Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction. Commun Biol. 2018;1:178 pubmed publisher
Heydt Q, Larrue C, Saland E, Bertoli S, Sarry J, Besson A, et al. Oncogenic FLT3-ITD supports autophagy via ATF4 in acute myeloid leukemia. Oncogene. 2017;: pubmed publisher
Linares J, Cordes T, Duran A, Reina Campos M, Valencia T, Ahn C, et al. ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma. Cell Metab. 2017;26:817-829.e6 pubmed publisher
Krug A, Gutbier S, Zhao L, Pöltl D, Kullmann C, Ivanova V, et al. Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+). Cell Death Dis. 2014;5:e1222 pubmed publisher
Hensen S, Heldens L, van Genesen S, Pruijn G, Lubsen N. A delayed antioxidant response in heat-stressed cells expressing a non-DNA binding HSF1 mutant. Cell Stress Chaperones. 2013;18:455-73 pubmed publisher
product information
Catalog Number :
sc-35112
Product Name :
ATF-4 siRNA (h)
Product Type :
siRNA
Size :
10 µM
List Price :
293 USD
Immunogen :
ATF-4
Specificity :
human
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA