product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
GFAP (2E1) Antibody
catalog :
sc-33673
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2E1
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 41
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5g
  • western blot; mouse; loading ...; fig 5e
Li J, Chiu J, Ramanjulu M, Blass B, Pratico D. A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles. Mol Neurodegener. 2020;15:1 pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig 5a
di Meco A, Pratico D. Early-life exposure to high-fat diet influences brain health in aging mice. Aging Cell. 2019;18:e13040 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:1000; loading ...; fig 6a
Koike T, Tanaka S, Hirahara Y, Oe S, Kurokawa K, Maeda M, et al. Morphological characteristics of p75 neurotrophin receptor-positive cells define a new type of glial cell in the rat dorsal root ganglia. J Comp Neurol. 2019;527:2047-2060 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 7
Hamdan H, Patyal P, Kockara N, Wight P. The wmN1 enhancer region in intron 1 is required for expression of human PLP1. Glia. 2018;66:1763-1774 pubmed publisher
  • western blot; mouse; fig 5d
Li J, Barrero C, Merali S, Pratico D. Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer's phenotype. Sci Rep. 2017;7:46002 pubmed publisher
  • western blot; human; fig s1d
Torres A, Vargas Y, Uribe D, Jaramillo C, Gleisner A, Salazar Onfray F, et al. Adenosine A3 receptor elicits chemoresistance mediated by multiple resistance-associated protein-1 in human glioblastoma stem-like cells. Oncotarget. 2016;7:67373-67386 pubmed publisher
  • immunohistochemistry; mouse; 1:50; fig 4a
  • western blot; mouse; 1:500; fig 9
Caporali P, Bruno F, Palladino G, Dragotto J, Petrosini L, Mangia F, et al. Developmental delay in motor skill acquisition in Niemann-Pick C1 mice reveals abnormal cerebellar morphogenesis. Acta Neuropathol Commun. 2016;4:94 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 4n
Anastasiadou S, Knöll B. The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration. Exp Neurol. 2016;279:243-260 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 3
  • western blot; mouse; 1:200; fig 3
Lauretti E, Di Meco A, Merali S, Praticò D. Chronic behavioral stress exaggerates motor deficit and neuroinflammation in the MPTP mouse model of Parkinson's disease. Transl Psychiatry. 2016;6:e733 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:500; loading ...; fig 7a
Baranowska Bosiacka I, Listos J, Gutowska I, Machoy Mokrzynska A, Kolasa Wołosiuk A, Tarnowski M, et al. Effects of perinatal exposure to lead (Pb) on purine receptor expression in the brain and gliosis in rats tolerant to morphine analgesia. Toxicology. 2016;339:19-33 pubmed publisher
  • western blot; rat; fig 7
Xue T, Wei L, Zha D, Qiao L, Lu L, Chen F, et al. Exposure to acoustic stimuli promotes the development and differentiation of neural stem cells from the cochlear nuclei through the clusterin pathway. Int J Mol Med. 2015;35:637-44 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:300
  • western blot; mouse; 1:400
Lauretti E, di Meco A, Chu J, Praticò D. Modulation of AD neuropathology and memory impairments by the isoprostane F2α is mediated by the thromboxane receptor. Neurobiol Aging. 2015;36:812-20 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:300; loading ...; fig 7a
Nardai S, Dobolyi A, Pál G, Skopál J, Pintér N, Lakatos K, et al. Selegiline promotes NOTCH-JAGGED signaling in astrocytes of the peri-infarct region and improves the functional integrity of the neurovascular unit in a rat model of focal ischemia. Restor Neurol Neurosci. 2015;33:1-14 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:40; loading ...; fig 5a
Neher M, Rich M, Keene C, Weckbach S, Bolden A, Losacco J, et al. Deficiency of complement receptors CR2/CR1 in Cr2?/? mice reduces the extent of secondary brain damage after closed head injury. J Neuroinflammation. 2014;11:95 pubmed publisher
  • immunocytochemistry; rat; 1:300
  • western blot; rat; 1:400
Gao X, Zhang J, Zhang J, Zou H, Liu J. Identification of rat respiratory mucosa stem cells and comparison of the early neural differentiation potential with the bone marrow mesenchymal stem cells in vitro. Cell Mol Neurobiol. 2014;34:257-68 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:300; loading ...; fig 5
Dobolyi A, Ostergaard E, Bagó A, Doczi T, Palkovits M, Gal A, et al. Exclusive neuronal expression of SUCLA2 in the human brain. Brain Struct Funct. 2015;220:135-51 pubmed publisher
  • immunohistochemistry; human
Chapuis J, Hansmannel F, Gistelinck M, Mounier A, Van Cauwenberghe C, Kolen K, et al. Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology. Mol Psychiatry. 2013;18:1225-34 pubmed publisher
Lauretti E, Nenov M, Dincer O, Iuliano L, Pratico D. Extra virgin olive oil improves synaptic activity, short-term plasticity, memory, and neuropathology in a tauopathy model. Aging Cell. 2020;19:e13076 pubmed publisher
Badshah H, Ikram M, Ali W, Ahmad S, Hahm J, Kim M. Caffeine May Abrogate LPS-Induced Oxidative Stress and Neuroinflammation by Regulating Nrf2/TLR4 in Adult Mouse Brains. Biomolecules. 2019;9: pubmed publisher
Li J, Chiu J, Pratico D. Full recovery of the Alzheimer's disease phenotype by gain of function of vacuolar protein sorting 35. Mol Psychiatry. 2019;: pubmed publisher
Stevenson M, Lensmire N, Swain R. Astrocytes and radial glia-like cells, but not neurons, display a nonapoptotic increase in caspase-3 expression following exercise. Brain Behav. 2018;8:e01110 pubmed publisher
Torres A, Arriagada V, Erices J, Toro M, Rocha J, Niechi I, et al. FK506 Attenuates the MRP1-Mediated Chemoresistant Phenotype in Glioblastoma Stem-Like Cells. Int J Mol Sci. 2018;19: pubmed publisher
di Meco A, Li J, Barrero C, Merali S, Pratico D. Elevated levels of brain homocysteine directly modulate the pathological phenotype of a mouse model of tauopathy. Mol Psychiatry. 2018;: pubmed publisher
Barragán Iglesias P, Lou T, Bhat V, Megat S, Burton M, Price T, et al. Inhibition of Poly(A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice. Nat Commun. 2018;9:10 pubmed publisher
Gey M, Wanner R, Schilling C, Pedro M, Sinske D, Knöll B. Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury. Open Biol. 2016;6: pubmed publisher
Listos J, Baranowska Bosiacka I, Wasik A, Talarek S, Tarnowski M, Listos P, et al. The adenosinergic system is involved in sensitization to morphine withdrawal signs in rats-neurochemical and molecular basis in dopaminergic system. Psychopharmacology (Berl). 2016;233:2383-97 pubmed publisher
García Pérez D, Laorden M, Milanés M. Regulation of Pleiotrophin, Midkine, Receptor Protein Tyrosine Phosphatase β/ζ, and Their Intracellular Signaling Cascades in the Nucleus Accumbens During Opiate Administration. Int J Neuropsychopharmacol. 2015;19: pubmed publisher
Prast J, Schardl A, Sartori S, Singewald N, Saria A, Zernig G. Increased conditioned place preference for cocaine in high anxiety related behavior (HAB) mice is associated with an increased activation in the accumbens corridor. Front Behav Neurosci. 2014;8:441 pubmed publisher
Prast J, Schardl A, Schwarzer C, Dechant G, Saria A, Zernig G. Reacquisition of cocaine conditioned place preference and its inhibition by previous social interaction preferentially affect D1-medium spiny neurons in the accumbens corridor. Front Behav Neurosci. 2014;8:317 pubmed publisher
Wang Y, Zhang Y, Qian C, Cai M, Li Y, Li Z, et al. GSK3?/?-catenin signaling is correlated with the differentiation of glioma cells induced by wogonin. Toxicol Lett. 2013;222:212-23 pubmed publisher
Wang Y, Sun M, Hou Q, Hamilton K. GABAergic inhibition through synergistic astrocytic neuronal interaction transiently decreases vasopressin neuronal activity during hypoosmotic challenge. Eur J Neurosci. 2013;37:1260-9 pubmed publisher
Pál G, Vincze C, Renner E, Wappler E, Nagy Z, Lovas G, et al. Time course, distribution and cell types of induction of transforming growth factor betas following middle cerebral artery occlusion in the rat brain. PLoS ONE. 2012;7:e46731 pubmed publisher
Zhang X, Li L, Zhang X, Xie W, Li L, Yang D, et al. Prenatal hypoxia may aggravate the cognitive impairment and Alzheimer's disease neuropathology in APPSwe/PS1A246E transgenic mice. Neurobiol Aging. 2013;34:663-78 pubmed publisher
Shimazawa M, Miwa A, Ito Y, Tsuruma K, Aihara M, Hara H. Involvement of endoplasmic reticulum stress in optic nerve degeneration following N-methyl-D-aspartate-induced retinal damage in mice. J Neurosci Res. 2012;90:1960-9 pubmed publisher
Molnár T, Dobolyi A, Nyitrai G, Barabas P, Héja L, Emri Z, et al. Calcium signals in the nucleus accumbens: activation of astrocytes by ATP and succinate. BMC Neurosci. 2011;12:96 pubmed publisher
Tiago T, Marques da Silva D, Samhan Arias A, Aureliano M, Gutierrez Merino C. Early disruption of the actin cytoskeleton in cultured cerebellar granule neurons exposed to 3-morpholinosydnonimine-oxidative stress is linked to alterations of the cytosolic calcium concentration. Cell Calcium. 2011;49:174-83 pubmed publisher
Héja L, Barabas P, Nyitrai G, Kekesi K, Lasztóczi B, Toke O, et al. Glutamate uptake triggers transporter-mediated GABA release from astrocytes. PLoS ONE. 2009;4:e7153 pubmed publisher
Roberts J, Ossipov M, Porreca F. Glial activation in the rostroventromedial medulla promotes descending facilitation to mediate inflammatory hypersensitivity. Eur J Neurosci. 2009;30:229-41 pubmed publisher
Zhai J, Strom A, Kilty R, Venkatakrishnan P, White J, Everson W, et al. Proteomic characterization of lipid raft proteins in amyotrophic lateral sclerosis mouse spinal cord. FEBS J. 2009;276:3308-23 pubmed publisher
Muhammad S, Barakat W, Stoyanov S, Murikinati S, Yang H, Tracey K, et al. The HMGB1 receptor RAGE mediates ischemic brain damage. J Neurosci. 2008;28:12023-12031 pubmed publisher
Tsuchiya A, Hayashi T, Deguchi K, Sehara Y, Yamashita T, Zhang H, et al. Expression of netrin-1 and its receptors DCC and neogenin in rat brain after ischemia. Brain Res. 2007;1159:1-7 pubmed
product information
Product Name :
GFAP (2E1) Antibody
Gene Name :
GFAP
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-33673
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
GFAP
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P)
Epitope :
FL (bovine)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA