product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Parafibromin (2H1) Antibody
catalog :
sc-33638
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2H1
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 16
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 3c
Drelon C, Berthon A, Sahut-Barnola I, Mathieu M, Dumontet T, Rodriguez S, et al. PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development. Nat Commun. 2016;7:12751 pubmed publisher
  • western blot; human; fig 1c
Cao Q, Yamamoto J, Isobe T, Tateno S, Murase Y, Chen Y, et al. Characterization of the Human Transcription Elongation Factor Rtf1: Evidence for Nonoverlapping Functions of Rtf1 and the Paf1 Complex. Mol Cell Biol. 2015;35:3459-70 pubmed publisher
Zheng H, Xu X, Xing Y, Wei Z, Takahashi H, Masuda S, et al. Nuclear or cytoplasmic localization of Bag-1 distinctly correlates with pathologic behavior and outcome of gastric carcinomas. Hum Pathol. 2010;41:724-36 pubmed publisher
Porzionato A, Macchi V, Barzon L, Masi G, Iacobone M, Parenti A, et al. Immunohistochemical assessment of parafibromin in mouse and human tissues. J Anat. 2006;209:817-27 pubmed
Corbetta S, Vaira V, Guarnieri V, Scillitani A, Eller-Vainicher C, Ferrero S, et al. Differential expression of microRNAs in human parathyroid carcinomas compared with normal parathyroid tissue. Endocr Relat Cancer. 2010;17:135-46 pubmed publisher
Guarnieri V, Battista C, Muscarella L, Bisceglia M, de Martino D, Baorda F, et al. CDC73 mutations and parafibromin immunohistochemistry in parathyroid tumors: clinical correlations in a single-centre patient cohort. Cell Oncol (Dordr). 2012;35:411-22 pubmed publisher
Kim H, Oh Y, Kim S, Lee D, Kang H, Lee J, et al. Parafibromin immunohistochemical staining to differentiate parathyroid carcinoma from parathyroid adenoma. Head Neck. 2012;34:201-6 pubmed publisher
Masi G, Barzon L, Iacobone M, Viel G, Porzionato A, Macchi V, et al. Clinical, genetic, and histopathologic investigation of CDC73-related familial hyperparathyroidism. Endocr Relat Cancer. 2008;15:1115-26 pubmed publisher
De Mesquita Netto A, Gomez R, Diniz M, Fonseca-Silva T, Campos K, De Marco L, et al. Assessing the contribution of HRPT2 to the pathogenesis of jaw fibrous dysplasia, ossifying fibroma, and osteosarcoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115:359-67 pubmed publisher
Masi G, Iacobone M, Sinigaglia A, Mantelli B, Pennelli G, Castagliuolo I, et al. Characterization of a new CDC73 missense mutation that impairs Parafibromin expression and nucleolar localization. PLoS ONE. 2014;9:e97994 pubmed publisher
Cascon A, Huarte-Mendicoa C, Javier Leandro-García L, Leton R, Suela J, Santana A, et al. Detection of the first gross CDC73 germline deletion in an HPT-JT syndrome family. Genes Chromosomes Cancer. 2011;50:922-9 pubmed publisher
Cavaco B, Santos R, Felix A, Carvalho D, Lopes J, Domingues R, et al. Identification of de novo germline mutations in the HRPT2 gene in two apparently sporadic cases with challenging parathyroid tumor diagnoses. Endocr Pathol. 2011;22:44-52 pubmed publisher
Korpi-Hyovalti E, Cranston T, Ryhänen E, Arola J, Aittomaki K, Sane T, et al. CDC73 intragenic deletion in familial primary hyperparathyroidism associated with parathyroid carcinoma. J Clin Endocrinol Metab. 2014;99:3044-8 pubmed publisher
Zheng H, Takahashi H, Li X, Hara T, Masuda S, Guan Y, et al. Downregulated parafibromin expression is a promising marker for pathogenesis, invasion, metastasis and prognosis of gastric carcinomas. Virchows Arch. 2008;452:147-55 pubmed
Fernandez-Ranvier G, Khanafshar E, Tacha D, Wong M, Kebebew E, Duh Q, et al. Defining a molecular phenotype for benign and malignant parathyroid tumors. Cancer. 2009;115:334-44 pubmed publisher
Sulaiman L, Nilsson I, Juhlin C, Haglund F, Höög A, Larsson C, et al. Genetic characterization of large parathyroid adenomas. Endocr Relat Cancer. 2012;19:389-407 pubmed publisher
product information
Product Name :
Parafibromin (2H1) Antibody
Gene Name :
CDC73
Size :
200 µg/ml
Price :
279 USD
Catalog Number :
sc-33638
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
Parafibromin
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P)
Epitope :
87-100 (m)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
www.scbt.com
1.800.457.3801
headquarters: USA