product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
NQO1 (A180) Antibody
catalog :
sc-32793
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A180
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:500; loading ...; fig 5e
Wang L, Lavier J, Hua W, Wang Y, Gong L, Wei H, et al. High-Intensity Interval Training and Moderate-Intensity Continuous Training Attenuate Oxidative Damage and Promote Myokine Response in the Skeletal Muscle of ApoE KO Mice on High-Fat Diet. Antioxidants (Basel). 2021;10: pubmed publisher
  • western blot; human; 1:500; loading ...; fig 6b, s7d
Totten S, Im Y, Cepeda Cañedo E, Najyb O, Nguyen A, Hebert S, et al. STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer. Nat Commun. 2021;12:3299 pubmed publisher
  • western blot; mouse; loading ...; fig s10c
Xue X, Bredell B, Anderson E, Martin A, Mays C, Nagao Kitamoto H, et al. Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer. Proc Natl Acad Sci U S A. 2017;114:E9608-E9617 pubmed publisher
  • western blot; human; fig 4
Sachweh M, Stafford W, Drummond C, McCarthy A, Higgins M, Campbell J, et al. Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells. Oncotarget. 2015;6:16488-506 pubmed
  • western blot; human
Miyazawa M, Tsuji Y. Evidence for a novel antioxidant function and isoform-specific regulation of the human p66Shc gene. Mol Biol Cell. 2014;25:2116-27 pubmed publisher
  • western blot; rat; 1:250
Yao W, Luo G, Zhu G, Chi X, Zhang A, Xia Z, et al. Propofol activation of the Nrf2 pathway is associated with amelioration of acute lung injury in a rat liver transplantation model. Oxid Med Cell Longev. 2014;2014:258567 pubmed publisher
  • western blot; human
Hemachandra L, Patel H, Chandrasena R, Choi J, Piyankarage S, Wang S, et al. SERMs attenuate estrogen-induced malignant transformation of human mammary epithelial cells by upregulating detoxification of oxidative metabolites. Cancer Prev Res (Phila). 2014;7:505-15 pubmed publisher
  • western blot; human; 1:1000
Hanada N, Takahata T, Zhou Q, Ye X, Sun R, Itoh J, et al. Methylation of the KEAP1 gene promoter region in human colorectal cancer. BMC Cancer. 2012;12:66 pubmed publisher
Lee S, Jee S, Kim M, Kim S, Shin M, Kim Y, et al. Curcumin Suppresses the Lipid Accumulation and Oxidative Stress Induced by Benzo[a]pyrene Toxicity in HepG2 Cells. Antioxidants (Basel). 2021;10: pubmed publisher
Yan J, Huang J, Liu A, Wu J, Fan H, Shen M, et al. Atorvastatin improves motor function, anxiety and depression by NOX2-mediated autophagy and oxidative stress in MPTP-lesioned mice. Aging (Albany NY). 2020;13:831-845 pubmed publisher
Glorieux C, Buc Calderon P. Cancer Cell Sensitivity to Redox-Cycling Quinones is Influenced by NAD(P)H: Quinone Oxidoreductase 1 Polymorphism. Antioxidants (Basel). 2019;8: pubmed publisher
Luo S, Kang S, Wang Z, Liu X, Day J, Wu Z, et al. Akt Phosphorylates NQO1 and Triggers its Degradation, Abolishing Its Antioxidative Activities in Parkinson's Disease. J Neurosci. 2019;39:7291-7305 pubmed publisher
Han G, Kang H, Chung S, Lim C, Linton J, Lee J, et al. Novel Neohesperidin Dihydrochalcone Analogue Inhibits Adipogenic Differentiation of Human Adipose-Derived Stem Cells through the Nrf2 Pathway. Int J Mol Sci. 2018;19: pubmed publisher
Lu K, Alcivar A, Ma J, Foo T, Zywea S, Mahdi A, et al. NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress-Induced DPP3-KEAP1 Interaction. Cancer Res. 2017;77:2881-2892 pubmed publisher
Hadley K, Hendricks D. Use of NQO1 status as a selective biomarker for oesophageal squamous cell carcinomas with greater sensitivity to 17-AAG. BMC Cancer. 2014;14:334 pubmed publisher
Yang Y, Zhang Y, Wu Q, Cui X, Lin Z, Liu S, et al. Clinical implications of high NQO1 expression in breast cancers. J Exp Clin Cancer Res. 2014;33:14 pubmed publisher
Gao S, Duan X, Wang X, Dong D, Liu D, Li X, et al. Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion. Food Chem Toxicol. 2013;59:739-47 pubmed publisher
Ziros P, Manolakou S, Habeos I, Lilis I, Chartoumpekis D, Koika V, et al. Nrf2 is commonly activated in papillary thyroid carcinoma, and it controls antioxidant transcriptional responses and viability of cancer cells. J Clin Endocrinol Metab. 2013;98:E1422-7 pubmed publisher
Scarpa E, Bonfili L, Eleuteri A, La Teana A, Brugè F, Bertoli E, et al. ATP independent proteasomal degradation of NQO1 in BL cell lines. Biochimie. 2012;94:1242-9 pubmed
Satsu H, Chidachi E, Hiura Y, Ogiwara H, Gondo Y, Shimizu M. Induction of NAD(P)H:quinone oxidoreductase 1 expression by cysteine via Nrf2 activation in human intestinal epithelial LS180 cells. Amino Acids. 2012;43:1547-555 pubmed
Kim S, Lim J, Bang Y, Gal J, Lee S, Cho Y, et al. Licochalcone E activates Nrf2/antioxidant response element signaling pathway in both neuronal and microglial cells: therapeutic relevance to neurodegenerative disease. J Nutr Biochem. 2012;23:1314-23 pubmed publisher
Tebbi A, Guittet O, Cottet M, Vesin M, Lepoivre M. TAp73 induction by nitric oxide: regulation by checkpoint kinase 1 (CHK1) and protection against apoptosis. J Biol Chem. 2011;286:7873-84 pubmed publisher
product information
Product Name :
NQO1 (A180) Antibody
Gene Name :
NQO1
Size :
200 µg/ml
Catalog Number :
sc-32793
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
NQO1
reactive species  :
h, m > r
Application :
WB, IP, IF, IHC(P)
Epitope :
FL (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA