product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
ARID1A (PSG3) Antibody
catalog :
sc-32761
quantity :
200 µg/ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PSG3
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, RNA immunoprecipitation
citations: 38
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1
Bi C, Liu M, Rong W, Wu F, Zhang Y, Lin S, et al. High Beclin-1 and ARID1A expression corelates with poor survival and high recurrence in intrahepatic cholangiocarcinoma: a histopathological retrospective study. BMC Cancer. 2019;19:213 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 2b
  • western blot; mouse; loading ...; fig 1d
Alpsoy A, Dykhuizen E. Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes. J Biol Chem. 2018;293:3892-3903 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1-s1a
Kelso T, Porter D, Amaral M, Shokhirev M, Benner C, Hargreaves D. Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers. elife. 2017;6: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3f
Bitler B, Wu S, Park P, Hai Y, Aird K, Wang Y, et al. ARID1A-mutated ovarian cancers depend on HDAC6 activity. Nat Cell Biol. 2017;19:962-973 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; fig 2
Wu Y, Gu Y, Guo S, Dai Q, Zhang W. Expressing Status and Correlation of ARID1A and Histone H2B on Breast Cancer. Biomed Res Int. 2016;2016:7593787 pubmed publisher
  • RNA immunoprecipitation; mouse; fig s5
  • western blot; mouse
Flynn R, Do B, Rubin A, Calo E, Lee B, Kuchelmeister H, et al. 7SK-BAF axis controls pervasive transcription at enhancers. Nat Struct Mol Biol. 2016;23:231-8 pubmed publisher
  • immunohistochemistry; mouse; 1:50; loading ...; fig 2c
Chandler R, Magnuson T. The SWI/SNF BAF-A complex is essential for neural crest development. Dev Biol. 2016;411:15-24 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:150; loading ...; fig 1
Cho H, Lee J, Jung H, Oh M, Lee J, Jang S, et al. Loss of Tumor Suppressor ARID1A Protein Expression Correlates with Poor Prognosis in Patients with Primary Breast Cancer. J Breast Cancer. 2015;18:339-46 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:150; fig 3
  • western blot; human; 1:500; fig s22
Witkiewicz A, McMillan E, Balaji U, Baek G, Lin W, Mansour J, et al. Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets. Nat Commun. 2015;6:6744 pubmed publisher
  • immunoprecipitation; human; 1:10; fig s9
Fillmore C, Xu C, Desai P, Berry J, Rowbotham S, Lin Y, et al. EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors. Nature. 2015;520:239-42 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50
Chandler R, Damrauer J, Raab J, Schisler J, Wilkerson M, Didion J, et al. Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling. Nat Commun. 2015;6:6118 pubmed publisher
  • immunohistochemistry; human; 1:300; fig 2, 3
Nordentoft I, Lamy P, Birkenkamp Demtroder K, Shumansky K, Vang S, Hornshøj H, et al. Mutational context and diverse clonal development in early and late bladder cancer. Cell Rep. 2014;7:1649-1663 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
  • chromatin immunoprecipitation; mouse
  • immunoprecipitation; mouse
  • western blot; mouse
Singh A, Archer T. Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation. Nucleic Acids Res. 2014;42:2958-75 pubmed publisher
  • chromatin immunoprecipitation; mouse
  • immunoprecipitation; mouse
Chandler R, Brennan J, Schisler J, Serber D, Patterson C, Magnuson T. ARID1a-DNA interactions are required for promoter occupancy by SWI/SNF. Mol Cell Biol. 2013;33:265-80 pubmed publisher
Zhang X, Shetty M, Clemente V, Linder S, Bazzaro M. Targeting Mitochondrial Metabolism in Clear Cell Carcinoma of the Ovaries. Int J Mol Sci. 2021;22: pubmed publisher
Zhang J, Hou S, You Z, Li G, Xu S, Li X, et al. Expression and prognostic values of ARID family members in breast cancer. Aging (Albany NY). 2021;13:5621-5637 pubmed publisher
Shin H, Yang W, Chay D, Lee E, Chung J, Kim H, et al. Tetraspanin 1 promotes endometriosis leading to ovarian clear cell carcinoma. Mol Oncol. 2020;: pubmed publisher
Imai Sumida M, Dasgupta P, Kulkarni P, Shiina M, Hashimoto Y, Shahryari V, et al. Genistein Represses HOTAIR/Chromatin Remodeling Pathways to Suppress Kidney Cancer. Cell Physiol Biochem. 2020;54:53-70 pubmed publisher
Riebensahm C, Joosse S, Mohme M, Hanssen A, Matschke J, Goy Y, et al. Clonality of circulating tumor cells in breast cancer brain metastasis patients. Breast Cancer Res. 2019;21:101 pubmed publisher
Pinto D, Scott T, DeMarino C, Pleet M, Vo T, Saifuddin M, et al. Effect of transcription inhibition and generation of suppressive viral non-coding RNAs. Retrovirology. 2019;16:13 pubmed publisher
Ideno N, Yamaguchi H, Okumura T, Huang J, Brun M, Ho M, et al. A pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9-mediated somatic recombination. Lab Invest. 2019;: pubmed publisher
Gatchalian J, Malik S, Ho J, Lee D, Kelso T, Shokhirev M, et al. A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells. Nat Commun. 2018;9:5139 pubmed publisher
Wu C, Lyu J, Yang E, Liu Y, Zhang B, Shim J. Targeting AURKA-CDC25C axis to induce synthetic lethality in ARID1A-deficient colorectal cancer cells. Nat Commun. 2018;9:3212 pubmed publisher
Livshits G, Alonso Curbelo D, Morris J, Koche R, Saborowski M, Wilkinson J, et al. Arid1a restrains Kras-dependent changes in acinar cell identity. elife. 2018;7: pubmed publisher
Lakshminarasimhan R, Andreu Vieyra C, Lawrenson K, Duymich C, Gayther S, Liang G, et al. Down-regulation of ARID1A is sufficient to initiate neoplastic transformation along with epigenetic reprogramming in non-tumorigenic endometriotic cells. Cancer Lett. 2017;401:11-19 pubmed publisher
Porter E, Dykhuizen E. Individual Bromodomains of Polybromo-1 Contribute to Chromatin Association and Tumor Suppression in Clear Cell Renal Carcinoma. J Biol Chem. 2017;292:2601-2610 pubmed publisher
Kato M, Takano M, Miyamoto M, Sasaki N, Goto T, Suzuki A, et al. Effect of ARID1A/BAF250a expression on carcinogenesis and clinicopathological factors in pure-type clear cell adenocarcinoma of the ovary. Mol Clin Oncol. 2016;5:395-401 pubmed
Bitler B, Aird K, Garipov A, Li H, Amatangelo M, Kossenkov A, et al. Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers. Nat Med. 2015;21:231-8 pubmed publisher
Chung H, Cho H, Perry C, Song J, Ylaya K, Lee H, et al. Downregulation of ERp57 expression is associated with poor prognosis in early-stage cervical cancer. Biomarkers. 2013;18:573-9 pubmed publisher
Cho H, Kim J, Chung H, Perry C, Lee H, Kim J. Loss of ARID1A/BAF250a expression is linked to tumor progression and adverse prognosis in cervical cancer. Hum Pathol. 2013;44:1365-74 pubmed publisher
Rawish K, Desouki M, Crispens M, Fadare O. Conventional endometrioid adenocarcinomas of the endometrium recurring as clear cell tumors: comparative immunohistochemical analyses. Ann Diagn Pathol. 2013;17:270-5 pubmed publisher
Weigert O, Kopp N, Lane A, Yoda A, Dahlberg S, Neuberg D, et al. Molecular ontogeny of donor-derived follicular lymphomas occurring after hematopoietic cell transplantation. Cancer Discov. 2012;2:47-55 pubmed publisher
Fadare O, Renshaw I, Liang S. Does the Loss of ARID1A (BAF-250a) Expression in Endometrial Clear Cell Carcinomas Have Any Clinicopathologic Significance? A Pilot Assessment. J Cancer. 2012;3:129-36 pubmed publisher
Xu F, Flowers S, Moran E. Essential role of ARID2 protein-containing SWI/SNF complex in tissue-specific gene expression. J Biol Chem. 2012;287:5033-41 pubmed publisher
Zhang X, Zhang Y, Yang Y, Niu M, Sun S, Ji H, et al. Frequent low expression of chromatin remodeling gene ARID1A in breast cancer and its clinical significance. Cancer Epidemiol. 2012;36:288-93 pubmed publisher
Flores Alcantar A, Gonzalez Sandoval A, Escalante Alcalde D, Lomeli H. Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycle. Cell Tissue Res. 2011;345:137-48 pubmed publisher
Euskirchen G, Auerbach R, Davidov E, Gianoulis T, Zhong G, Rozowsky J, et al. Diverse roles and interactions of the SWI/SNF chromatin remodeling complex revealed using global approaches. PLoS Genet. 2011;7:e1002008 pubmed publisher
Flajollet S, Lefebvre B, Cudejko C, Staels B, Lefebvre P. The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor. Mol Cell Endocrinol. 2007;270:23-32 pubmed
product information
Product Name :
ARID1A (PSG3) Antibody
Gene Name :
ARID1A
Size :
200 µg/ml
Catalog Number :
sc-32761
Type :
Monoclonal
Host :
mouse monoclonal
Antigen :
ARID1A
reactive species  :
m, r, h
Application :
WB, IP, IF, IHC(P)
Epitope :
600-1018 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA