product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
p19 ARF (5-C3-1) Antibody
catalog :
sc-32748
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
5-C3-1
reactivity :
human, mouse, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 26
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; chicken; loading ...; fig s11
Rhinn M, Zapata Bodalo I, Klein A, Plassat J, Knauer Meyer T, Keyes W. Aberrant induction of p19Arf-mediated cellular senescence contributes to neurodevelopmental defects. PLoS Biol. 2022;20:e3001664 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 1e
Mikawa R, Sato T, Suzuki Y, Baskoro H, Kawaguchi K, Sugimoto M. p19Arf Exacerbates Cigarette Smoke-Induced Pulmonary Dysfunction. Biomolecules. 2020;10: pubmed publisher
  • western blot; mouse; loading ...; fig 4c
Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson F, et al. p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors. Cancer Cell. 2019;35:204-220.e9 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 9.a","b
Muzumdar M, Dorans K, Chung K, Robbins R, Tammela T, Gocheva V, et al. Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers. Nat Commun. 2016;7:12685 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Zhao J, Li H, Zhou R, Ma G, Dekker J, Tucker H, et al. Foxp1 Regulates the Proliferation of Hair Follicle Stem Cells in Response to Oxidative Stress during Hair Cycling. PLoS ONE. 2015;10:e0131674 pubmed publisher
  • western blot; human
Neo S, Itahana Y, Alagu J, Kitagawa M, Guo A, Lee S, et al. TRIM28 Is an E3 Ligase for ARF-Mediated NPM1/B23 SUMOylation That Represses Centrosome Amplification. Mol Cell Biol. 2015;35:2851-63 pubmed publisher
  • western blot; mouse; 1:200
Vinue A, Andrés Blasco I, Herrero Cervera A, Piqueras L, Andres V, Burks D, et al. Ink4/Arf locus restores glucose tolerance and insulin sensitivity by reducing hepatic steatosis and inflammation in mice with impaired IRS2-dependent signalling. Biochim Biophys Acta. 2015;1852:1729-42 pubmed publisher
  • western blot; mouse; fig s1
Yamakoshi K, Katano S, Iida M, Kimura H, Okuma A, Ikemoto Uezumi M, et al. Dysregulation of the Bmi-1/p16(Ink⁴a) pathway provokes an aging-associated decline of submandibular gland function. Aging Cell. 2015;14:616-24 pubmed publisher
  • western blot; mouse; loading ...; fig s4e
Zhang Q, Kuang H, Chen C, Yan J, Do Umehara H, Liu X, et al. The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation. Nat Immunol. 2015;16:458-66 pubmed publisher
  • western blot; mouse
Albers J, Danzer C, Rechsteiner M, Lehmann H, Brandt L, Hejhal T, et al. A versatile modular vector system for rapid combinatorial mammalian genetics. J Clin Invest. 2015;125:1603-19 pubmed publisher
  • western blot; human
Sabò A, Doni M, Amati B. SUMOylation of Myc-family proteins. PLoS ONE. 2014;9:e91072 pubmed publisher
  • immunoprecipitation; mouse
Horiguchi M, Koyanagi S, Hamdan A, Kakimoto K, Matsunaga N, Yamashita C, et al. Rhythmic control of the ARF-MDM2 pathway by ATF4 underlies circadian accumulation of p53 in malignant cells. Cancer Res. 2013;73:2639-49 pubmed publisher
  • western blot; mouse
Kuchenreuther M, Weber J. The ARF tumor-suppressor controls Drosha translation to prevent Ras-driven transformation. Oncogene. 2014;33:300-7 pubmed publisher
Zhu C, Soto Feliciano Y, Morris J, Huang C, Koche R, Ho Y, et al. MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer. elife. 2023;12: pubmed publisher
Vecchio E, Golino G, Pisano A, Albano F, Falcone C, Ceglia S, et al. IBTK contributes to B-cell lymphomagenesis in Eμ-myc transgenic mice conferring resistance to apoptosis. Cell Death Dis. 2019;10:320 pubmed publisher
Brandt L, Albers J, Hejhal T, Pfundstein S, Gonçalves A, Catalano A, et al. Mouse genetic background influences whether HrasG12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma. Oncotarget. 2018;9:19753-19766 pubmed publisher
Oldrini B, Curiel García A, Marques C, Matia V, Uluçkan O, Graña Castro O, et al. Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling. Nat Commun. 2018;9:1466 pubmed publisher
Gonçalves A, Adlesic M, Brandt S, Hejhal T, Harlander S, Sommer L, et al. Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells. Nat Commun. 2017;8:1466 pubmed publisher
Monasor A, Murga M, López Contreras A, Navas C, Gomez G, Pisano D, et al. INK4a/ARF limits the expansion of cells suffering from replication stress. Cell Cycle. 2013;12:1948-54 pubmed publisher
Gonzalez Navarro H, Vinue A, Sanz M, Delgado M, Pozo M, Serrano M, et al. Increased dosage of Ink4/Arf protects against glucose intolerance and insulin resistance associated with aging. Aging Cell. 2013;12:102-11 pubmed publisher
Taneja P, Maglic D, Kai F, Sugiyama T, Kendig R, Frazier D, et al. Critical roles of DMP1 in human epidermal growth factor receptor 2/neu-Arf-p53 signaling and breast cancer development. Cancer Res. 2010;70:9084-94 pubmed publisher
Takeuchi S, Takahashi A, Motoi N, Yoshimoto S, Tajima T, Yamakoshi K, et al. Intrinsic cooperation between p16INK4a and p21Waf1/Cip1 in the onset of cellular senescence and tumor suppression in vivo. Cancer Res. 2010;70:9381-90 pubmed publisher
Fernandez Marcos P, Pantoja C, Gonzalez Rodriguez A, Martin N, Flores J, Valverde A, et al. Normal proliferation and tumorigenesis but impaired pancreatic function in mice lacking the cell cycle regulator sei1. PLoS ONE. 2010;5:e8744 pubmed publisher
Courel M, Friesenhahn L, Lees J. E2f6 and Bmi1 cooperate in axial skeletal development. Dev Dyn. 2008;237:1232-42 pubmed publisher
Taneja P, Mallakin A, Matise L, Frazier D, Choudhary M, Inoue K. Repression of Dmp1 and Arf transcription by anthracyclins: critical roles of the NF-kappaB subunit p65. Oncogene. 2007;26:7457-66 pubmed
Mallakin A, Taneja P, Matise L, Willingham M, Inoue K. Expression of Dmp1 in specific differentiated, nonproliferating cells and its regulation by E2Fs. Oncogene. 2006;25:7703-13 pubmed
product information
Catalog Number :
sc-32748
Product Name :
p19 ARF (5-C3-1) Antibody
Product Type :
Monoclonal
Host Species :
rat
Clonality :
monoclonal
Clone Name :
5-C3-1
Isotype :
IgG2b
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
p19 ARF
Specificity :
mouse, rat
Uses :
WB, IP, IF
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA