product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Topo I (C-21) Antibody
catalog :
sc-32736
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-21
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4c
Oo J, Irmer B, Günther S, Warwick T, Palfi K, Izquierdo Ponce J, et al. ZNF354C is a transcriptional repressor that inhibits endothelial angiogenic sprouting. Sci Rep. 2020;10:19079 pubmed publisher
  • western blot; human; fig 1a
Makhov P, Naito S, Haifler M, Kutikov A, Boumber Y, Uzzo R, et al. The convergent roles of NF-κB and ER stress in sunitinib-mediated expression of pro-tumorigenic cytokines and refractory phenotype in renal cell carcinoma. Cell Death Dis. 2018;9:374 pubmed publisher
  • western blot; human; loading ...; fig s2a
Meisenberg C, Ashour M, El Shafie L, Liao C, Hodgson A, Pilborough A, et al. Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan. Nucleic Acids Res. 2017;45:1159-1176 pubmed publisher
  • western blot; human; fig 1
Das S, Rehman I, Ghosh A, Sengupta S, Majumdar P, Jana B, et al. Poly(ADP-ribose) polymers regulate DNA topoisomerase I (Top1) nuclear dynamics and camptothecin sensitivity in living cells. Nucleic Acids Res. 2016;44:8363-75 pubmed publisher
  • western blot; human; loading ...; fig 4a
Spoelstra N, Cittelly D, Christenson J, Gordon M, Elias A, Jedlicka P, et al. Dicer expression in estrogen receptor-positive versus triple-negative breast cancer: an antibody comparison. Hum Pathol. 2016;56:40-51 pubmed publisher
  • flow cytometry; human; fig 4
  • western blot; human; fig 4
Liu Y, Ban L, Su X, Gao S, Liu J, Cui X. Effects of cinobufacini injection on cell proliferation and the expression of topoisomerases in human HepG-2 hepatocellular carcinoma cells. Mol Med Rep. 2015;12:1598-604 pubmed publisher
Walker C, Herranz Martin S, Karyka E, Liao C, Lewis K, Elsayed W, et al. C9orf72 expansion disrupts ATM-mediated chromosomal break repair. Nat Neurosci. 2017;20:1225-1235 pubmed publisher
Alagoz M, Wells O, El Khamisy S. TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy. Nucleic Acids Res. 2014;42:3089-103 pubmed publisher
Padmini E, Usha Rani M. Impact of seasonal variation on HSP70 expression quantitated in stressed fish hepatocytes. Comp Biochem Physiol B Biochem Mol Biol. 2008;151:278-85 pubmed publisher
product information
Catalog Number :
sc-32736
Product Name :
Topo I (C-21) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
C-21
Isotype :
IgM
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Topo I
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA