product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
PABP (10E10) Antibody
catalog :
sc-32318
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10E10
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 42
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; loading ...; fig 3e
  • western blot; human; 1:500; loading ...; fig s1e
Rai A, Chen J, Selbach M, Pelkmans L. Kinase-controlled phase transition of membraneless organelles in mitosis. Nature. 2018;559:211-216 pubmed publisher
  • western blot; human; loading ...; fig 6f
Tamarkin Ben Harush A, Vasseur J, Debart F, Ulitsky I, Dikstein R. Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress. elife. 2017;6: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2a
Nikolic J, Civas A, Lama Z, Lagaudrière Gesbert C, Blondel D. Rabies Virus Infection Induces the Formation of Stress Granules Closely Connected to the Viral Factories. PLoS Pathog. 2016;12:e1005942 pubmed publisher
  • western blot; human; loading ...; fig 2a
Klein G, Mathé C, Biola Clier M, Devineau S, Drouineau E, Hatem E, et al. RNA-binding proteins are a major target of silica nanoparticles in cell extracts. Nanotoxicology. 2016;10:1555-1564 pubmed
  • western blot; mouse; fig 2
  • western blot; human; fig 2
Gal J, Kuang L, Barnett K, Zhu B, Shissler S, Korotkov K, et al. ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics. Acta Neuropathol. 2016;132:563-76 pubmed publisher
  • immunocytochemistry; human; fig 2
Nelson E, Schmidt K, Deflubé L, Doğanay S, Banadyga L, Olejnik J, et al. Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions. J Virol. 2016;90:7268-7284 pubmed publisher
  • western blot; human; loading ...; fig 1b
Lyons S, Achorn C, Kedersha N, Anderson P, Ivanov P. YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression. Nucleic Acids Res. 2016;44:6949-60 pubmed publisher
  • immunocytochemistry; human; fig 4
Khaperskyy D, Schmaling S, Larkins Ford J, McCormick C, Gaglia M. Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein. PLoS Pathog. 2016;12:e1005427 pubmed publisher
  • western blot; human; fig s7
Suzuki Y, Chin W, Han Q, Ichiyama K, Lee C, Eyo Z, et al. Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication. PLoS Pathog. 2016;12:e1005357 pubmed publisher
  • western blot; human; 1:500; fig 1b
Vaysse C, Philippe C, Martineau Y, Quelen C, Hieblot C, Renaud C, et al. Key contribution of eIF4H-mediated translational control in tumor promotion. Oncotarget. 2015;6:39924-40 pubmed publisher
  • western blot; human; 1:500; fig s8
Gebhardt A, Habjan M, Benda C, Meiler A, Haas D, Hein M, et al. mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3. Nat Commun. 2015;6:8192 pubmed publisher
  • immunocytochemistry; human; 1:100; fig s7
Lenzi J, De Santis R, de Turris V, Morlando M, Laneve P, Calvo A, et al. ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons. Dis Model Mech. 2015;8:755-66 pubmed publisher
  • western blot; human; 1:200
Panas M, Kedersha N, McInerney G. Methods for the characterization of stress granules in virus infected cells. Methods. 2015;90:57-64 pubmed publisher
  • immunocytochemistry; human
Pène V, Li Q, Sodroski C, Hsu C, Liang T. Dynamic Interaction of Stress Granules, DDX3X, and IKK-α Mediates Multiple Functions in Hepatitis C Virus Infection. J Virol. 2015;89:5462-77 pubmed publisher
  • western blot; human; 1:100; fig 1
Sun S, Ling S, Qiu J, Albuquerque C, Zhou Y, Tokunaga S, et al. ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP. Nat Commun. 2015;6:6171 pubmed publisher
  • immunocytochemistry; human; 1:200
Rajgor D, Mellad J, Soong D, Rattner J, Fritzler M, Shanahan C. Mammalian microtubule P-body dynamics are mediated by nesprin-1. J Cell Biol. 2014;205:457-75 pubmed publisher
  • immunocytochemistry; human; tbl 2
Rozelle D, Filone C, Kedersha N, Connor J. Activation of stress response pathways promotes formation of antiviral granules and restricts virus replication. Mol Cell Biol. 2014;34:2003-16 pubmed publisher
  • immunocytochemistry; human; 1:100
  • western blot; human; 1:250
Copeland A, Altamura L, Van Deusen N, Schmaljohn C. Nuclear relocalization of polyadenylate binding protein during rift valley fever virus infection involves expression of the NSs gene. J Virol. 2013;87:11659-69 pubmed publisher
  • western blot; human; fig 6
Ariumi Y, Kuroki M, Kushima Y, Osugi K, Hijikata M, Maki M, et al. Hepatitis C virus hijacks P-body and stress granule components around lipid droplets. J Virol. 2011;85:6882-92 pubmed publisher
Bhagat R, Minaya M, Renganathan A, Mehra M, Marsh J, Martinez R, et al. Long non-coding RNA SNHG8 drives stress granule formation in tauopathies. medRxiv. 2023;: pubmed publisher
Qifti A, Balaji S, Scarlata S. Deformation of caveolae impacts global transcription and translation processes through relocalization of cavin-1. J Biol Chem. 2022;298:102005 pubmed publisher
Amemiya Y, Nakamura N, Ikeda N, Sugiyama R, Ishii C, Maki M, et al. Amino Acid-Mediated Intracellular Ca2+ Rise Modulates mTORC1 by Regulating the TSC2-Rheb Axis through Ca2+/Calmodulin. Int J Mol Sci. 2021;22: pubmed publisher
Slaine P, Kleer M, Duguay B, Pringle E, Kadijk E, Ying S, et al. Thiopurines activate an antiviral unfolded protein response that blocks influenza A virus glycoprotein accumulation. J Virol. 2021;: pubmed publisher
Villari G, Enrico Bena C, Del Giudice M, Gioelli N, Sandri C, Camillo C, et al. Distinct retrograde microtubule motor sets drive early and late endosome transport. EMBO J. 2020;:e103661 pubmed publisher
Hartenian E, Gilbertson S, Federspiel J, Cristea I, Glaunsinger B. RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupancy of host promoters but spares viral promoters. PLoS Pathog. 2020;16:e1008269 pubmed publisher
De Santis R, Alfano V, de Turris V, Colantoni A, Santini L, Garone M, et al. Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis. Cell Rep. 2019;27:3818-3831.e5 pubmed publisher
Gaucherand L, Porter B, Levene R, Price E, Schmaling S, Rycroft C, et al. The Influenza A Virus Endoribonuclease PA-X Usurps Host mRNA Processing Machinery to Limit Host Gene Expression. Cell Rep. 2019;27:776-792.e7 pubmed publisher
Duarte M, Vende P, Charpilienne A, Gratia M, Laroche C, Poncet D. Rotavirus Infection Alters Splicing of the Stress-Related Transcription Factor XBP1. J Virol. 2019;93: pubmed publisher
Gilbertson S, Federspiel J, Hartenian E, Cristea I, Glaunsinger B. Changes in mRNA abundance drive shuttling of RNA binding proteins, linking cytoplasmic RNA degradation to transcription. elife. 2018;7: pubmed publisher
Youn J, Dunham W, Hong S, Knight J, Bashkurov M, Chen G, et al. High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies. Mol Cell. 2018;69:517-532.e11 pubmed publisher
Barragán Iglesias P, Lou T, Bhat V, Megat S, Burton M, Price T, et al. Inhibition of Poly(A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice. Nat Commun. 2018;9:10 pubmed publisher
Jiang H, Wang W, Jiang X, Zeng W, Shen Z, Song Y, et al. ORF7 of Varicella-Zoster Virus Is Required for Viral Cytoplasmic Envelopment in Differentiated Neuronal Cells. J Virol. 2017;91: pubmed publisher
Rajgor D, Hanley J, Shanahan C. Identification of novel nesprin-1 binding partners and cytoplasmic matrin-3 in processing bodies. Mol Biol Cell. 2016;27:3894-3902 pubmed
Khaperskyy D, Emara M, Johnston B, Anderson P, Hatchette T, McCormick C. Influenza a virus host shutoff disables antiviral stress-induced translation arrest. PLoS Pathog. 2014;10:e1004217 pubmed publisher
Arnold M, Brownback C, Taraporewala Z, Patton J. Rotavirus variant replicates efficiently although encoding an aberrant NSP3 that fails to induce nuclear localization of poly(A)-binding protein. J Gen Virol. 2012;93:1483-94 pubmed publisher
Shih J, Wang W, Tsai T, Kuo C, Li H, Wu Lee Y. Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response. Biochem J. 2012;441:119-29 pubmed publisher
Jin J, Jing W, Lei X, Feng C, Peng S, Boris Lawrie K, et al. Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes. Nucleic Acids Res. 2011;39:3724-34 pubmed publisher
Cheshenko N, Trepanier J, Segarra T, Fuller A, Herold B. HSV usurps eukaryotic initiation factor 3 subunit M for viral protein translation: novel prevention target. PLoS ONE. 2010;5:e11829 pubmed publisher
Gal J, Zhang J, Kwinter D, Zhai J, Jia H, Jia J, et al. Nuclear localization sequence of FUS and induction of stress granules by ALS mutants. Neurobiol Aging. 2011;32:2323.e27-40 pubmed publisher
Aoyagi M, Gaspar M, Shenk T. Human cytomegalovirus UL69 protein facilitates translation by associating with the mRNA cap-binding complex and excluding 4EBP1. Proc Natl Acad Sci U S A. 2010;107:2640-5 pubmed publisher
Qiu C, Ma Y, Wang J, Peng S, Huang Y. Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells. Nucleic Acids Res. 2010;38:1240-8 pubmed publisher
Dang Y, Kedersha N, Low W, Romo D, Gorospe M, Kaufman R, et al. Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A. J Biol Chem. 2006;281:32870-8 pubmed
product information
Catalog Number :
sc-32318
Product Name :
PABP (10E10) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
10E10
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
PABP
Specificity :
human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA