product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
hnRNP L (4D11) Antibody
catalog :
sc-32317
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4D11
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, RNA immunoprecipitation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 6b
Xiu B, Chi Y, Liu L, Chi W, Zhang Q, Chen J, et al. LINC02273 drives breast cancer metastasis by epigenetically increasing AGR2 transcription. Mol Cancer. 2019;18:187 pubmed publisher
  • western blot; human; loading ...; fig 2
Xu L, Shen J, Jia J, Jia R. Inclusion of hnRNP L Alternative Exon 7 Is Associated with Good Prognosis and Inhibited by Oncogene SRSF3 in Head and Neck Squamous Cell Carcinoma. Biomed Res Int. 2019;2019:9612425 pubmed publisher
  • RNA immunoprecipitation; human; loading ...; fig s4b
  • immunohistochemistry - paraffin section; human; loading ...; fig 6b
Fei T, Chen Y, Xiao T, Li W, Cato L, Zhang P, et al. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc Natl Acad Sci U S A. 2017;114:E5207-E5215 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 6a
  • western blot; human; loading ...; fig 2b
Jia R, Zhang S, Liu M, Zhang Y, Liu Y, Fan M, et al. HnRNP L is important for the expression of oncogene SRSF3 and oncogenic potential of oral squamous cell carcinoma cells. Sci Rep. 2016;6:35976 pubmed publisher
  • western blot; human; 1:5000; fig 1
Wilhelmi I, Kanski R, Neumann A, Herdt O, Hoff F, Jacob R, et al. Sec16 alternative splicing dynamically controls COPII transport efficiency. Nat Commun. 2016;7:12347 pubmed publisher
  • western blot; human
Koumbadinga G, Mahmood N, Lei L, Kan Y, Cao W, Lobo V, et al. Increased stability of heterogeneous ribonucleoproteins by a deacetylase inhibitor. Biochim Biophys Acta. 2015;1849:1095-103 pubmed publisher
  • western blot; human; fig 3f
Nasrin F, Rahman M, Masuda A, Ohe K, Takeda J, Ohno K. HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform. Sci Rep. 2014;4:6841 pubmed publisher
  • RNA immunoprecipitation; human; loading ...; fig 6a
DERY K, Kujawski M, Grunert D, Wu X, Ngyuen T, Cheung C, et al. IRF-1 regulates alternative mRNA splicing of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in breast epithelial cells generating an immunoreceptor tyrosine-based inhibition motif (ITIM) containing isoform. Mol Cancer. 2014;13:64 pubmed publisher
Uppal S, Gegonne A, Chen Q, Thompson P, Cheng D, Mu J, et al. The Bromodomain Protein 4 Contributes to the Regulation of Alternative Splicing. Cell Rep. 2019;29:2450-2460.e5 pubmed publisher
DERY K, Silver C, Yang L, Shively J. Interferon regulatory factor 1 and a variant of heterogeneous nuclear ribonucleoprotein L coordinately silence the gene for adhesion protein CEACAM1. J Biol Chem. 2018;293:9277-9291 pubmed publisher
Rahman M, Masuda A, Ohe K, Ito M, Hutchinson D, Mayeda A, et al. HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA. Sci Rep. 2013;3:2931 pubmed publisher
Bieler S, Hammer E, Gesell Salazar M, Volker U, Stangl K, Meiners S. Low dose proteasome inhibition affects alternative splicing. J Proteome Res. 2012;11:3947-54 pubmed publisher
Rajan P, Dalgliesh C, Bourgeois C, Heiner M, Emami K, Clark E, et al. Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 Nuclear Bodies. BMC Cell Biol. 2009;10:82 pubmed publisher
product information
Catalog Number :
sc-32317
Product Name :
hnRNP L (4D11) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
4D11
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
hnRNP L
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA