product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
hnRNP C1/C2 (4F4) Antibody
catalog :
sc-32308
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4F4
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 26
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4c
Lin C, Huang P, Chen C, Wu M, Chen J, Chen J, et al. Sitagliptin attenuates arterial calcification by downregulating oxidative stress-induced receptor for advanced glycation end products in LDLR knockout mice. Sci Rep. 2021;11:17851 pubmed publisher
  • western blot; human; loading ...; fig s5c
Lee S, Mayr C. Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation. Mol Cell. 2019;: pubmed publisher
  • western blot; human; 1:3000; loading ...; fig s1e
Nozawa R, Boteva L, Soares D, Naughton C, Dun A, Buckle A, et al. SAF-A Regulates Interphase Chromosome Structure through Oligomerization with Chromatin-Associated RNAs. Cell. 2017;169:1214-1227.e18 pubmed publisher
  • western blot; human; loading ...; fig 4b
Aktas T, Avşar Ilık İ, Maticzka D, Bhardwaj V, Pessoa Rodrigues C, Mittler G, et al. DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome. Nature. 2017;544:115-119 pubmed publisher
  • western blot; human; 1:400; loading ...; fig 2c
García Heredia J, Lucena Cacace A, Verdugo Sivianes E, Pérez M, Carnero A. The Cargo Protein MAP17 (PDZK1IP1) Regulates the Cancer Stem Cell Pool Activating the Notch Pathway by Abducting NUMB. Clin Cancer Res. 2017;23:3871-3883 pubmed publisher
  • western blot; human; fig s3
Falaleeva M, Pages A, Matuszek Ż, Hidmi S, Agranat Tamir L, Korotkov K, et al. Dual function of C/D box small nucleolar RNAs in rRNA modification and alternative pre-mRNA splicing. Proc Natl Acad Sci U S A. 2016;113:E1625-34 pubmed publisher
  • western blot; human; 1:1000; fig 5D
Lin C, Huang P, Lai C, Chen J, Lin S, Chen J. Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1. PLoS ONE. 2015;10:e0143686 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 3
Walker E, Jensen L, Croft S, Ghildyal R. Variation in the nuclear effects of infection by different human rhinovirus serotypes. Front Microbiol. 2015;6:875 pubmed publisher
  • western blot; human; loading ...; fig S7a
Liu N, Dai Q, Zheng G, He C, Parisien M, Pan T. N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions. Nature. 2015;518:560-4 pubmed publisher
  • immunoprecipitation; human; fig 2 ug
  • western blot; human; fig 3f
Nasrin F, Rahman M, Masuda A, Ohe K, Takeda J, Ohno K. HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform. Sci Rep. 2014;4:6841 pubmed publisher
Ernst C, Duc J, Trono D. Efficient and sensitive profiling of RNA-protein interactions using TLC-CLIP. Nucleic Acids Res. 2023;51:e70 pubmed publisher
Price A, Steinbock R, Di C, Hayer K, Li Y, Herrmann C, et al. Adenovirus prevents dsRNA formation by promoting efficient splicing of viral RNA. Nucleic Acids Res. 2021;: pubmed publisher
Liu X, Zhou J, Mao Y, Ji Q, Qian S. Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates. Nat Chem Biol. 2019;15:865-871 pubmed publisher
Schultz A, Preussner M, Bunse M, Karni R, Heyd F. Activation-Dependent TRAF3 Exon 8 Alternative Splicing Is Controlled by CELF2 and hnRNP C Binding to an Upstream Intronic Element. Mol Cell Biol. 2017;37: pubmed publisher
Zhou R, Park J, Chun R, Lisse T, Garcia A, Zavala K, et al. Concerted effects of heterogeneous nuclear ribonucleoprotein C1/C2 to control vitamin D-directed gene transcription and RNA splicing in human bone cells. Nucleic Acids Res. 2017;45:606-618 pubmed publisher
García Heredia J, Verdugo Sivianes E, Lucena Cacace A, Molina Pinelo S, Carnero A. Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy. Oncotarget. 2016;7:63611-63628 pubmed publisher
Whisenant T, Peralta E, Aarreberg L, Gao N, Head S, Ordoukhanian P, et al. The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells. PLoS ONE. 2015;10:e0144409 pubmed publisher
Stubbs S, Conrad N. Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy. Nucleic Acids Res. 2015;43:504-19 pubmed publisher
Liu L, Karmakar S, Dhar R, Mahajan M, Choudhury A, Weissman S, et al. Regulation of G?-globin gene by ATF2 and its associated proteins through the cAMP-response element. PLoS ONE. 2013;8:e78253 pubmed publisher
Anantha R, Alcivar A, Ma J, Cai H, Simhadri S, Ule J, et al. Requirement of heterogeneous nuclear ribonucleoprotein C for BRCA gene expression and homologous recombination. PLoS ONE. 2013;8:e61368 pubmed publisher
Zarnack K, König J, Tajnik M, Martincorena I, Eustermann S, Stévant I, et al. Direct competition between hnRNP C and U2AF65 protects the transcriptome from the exonization of Alu elements. Cell. 2013;152:453-66 pubmed publisher
Luo L, Jin H, Huang H. Transferrin-cisplatin specifically deliver cisplatin to HepG2 cells in vitro and enhance cisplatin cytotoxicity. J Proteomics. 2012;77:237-50 pubmed publisher
Koryllou A, Patrinou Georgoula M, Dimozi A, Kyrtopoulos S, Pletsa V. Investigation of cell death induced by N-methyl-N-nitrosourea in cell lines of human origin and implication of RNA binding protein alterations. Anticancer Res. 2011;31:4291-9 pubmed
Lisse T, Liu T, Irmler M, Beckers J, Chen H, Adams J, et al. Gene targeting by the vitamin D response element binding protein reveals a role for vitamin D in osteoblast mTOR signaling. FASEB J. 2011;25:937-47 pubmed publisher
Goh E, Pardo O, Michael N, Niewiarowski A, Totty N, Volkova D, et al. Involvement of heterogeneous ribonucleoprotein F in the regulation of cell proliferation via the mammalian target of rapamycin/S6 kinase 2 pathway. J Biol Chem. 2010;285:17065-76 pubmed publisher
Koryllou A, Patrinou Georgoula M, Troungos C, Pletsa V. Cell death induced by N-methyl-N-nitrosourea, a model S(N)1 methylating agent, in two lung cancer cell lines of human origin. Apoptosis. 2009;14:1121-33 pubmed publisher
product information
Catalog Number :
sc-32308
Product Name :
hnRNP C1/C2 (4F4) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
4F4
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
hnRNP C1/C2
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA