product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
hnRNP A1 (4B10) Antibody
catalog :
sc-32301
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4B10
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, RNA immunoprecipitation, cross-linking immunoprecipitation
citations: 32
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig s8c
Van Alstyne M, Tattoli I, Delestrée N, Recinos Y, Workman E, Shihabuddin L, et al. Gain of toxic function by long-term AAV9-mediated SMN overexpression in the sensorimotor circuit. Nat Neurosci. 2021;24:930-940 pubmed publisher
  • western blot; human; loading ...; fig 4a
Zhu S, Chen W, Wang J, Qi L, Pan H, Feng Z, et al. SAM68 promotes tumorigenesis in lung adenocarcinoma by regulating metabolic conversion via PKM alternative splicing. Theranostics. 2021;11:3359-3375 pubmed publisher
  • western blot; human; 1:200; loading ...; fig 4s2a
Hayes L, Duan L, Bowen K, Kalab P, Rothstein J. C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import. elife. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig s4c
Liu H, Lorenzini P, Zhang F, Xu S, Wong M, Zheng J, et al. Alternative splicing analysis in human monocytes and macrophages reveals MBNL1 as major regulator. Nucleic Acids Res. 2018;46:6069-6086 pubmed publisher
  • western blot; human; loading ...; fig s5a
Marchesini M, Ogoti Y, Fiorini E, Aktaş Samur A, Nezi L, D Anca M, et al. ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma. Cancer Cell. 2017;32:88-100.e6 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5
Kumar S, Downie Ruiz Velasco A, Michlewski G. Oleic Acid Induces MiR-7 Processing through Remodeling of Pri-MiR-7/Protein Complex. J Mol Biol. 2017;429:1638-1649 pubmed publisher
  • western blot; human; loading ...; fig 3a
Vancevska A, Douglass K, Pfeiffer V, Manley S, Lingner J. The telomeric DNA damage response occurs in the absence of chromatin decompaction. Genes Dev. 2017;31:567-577 pubmed publisher
  • western blot; human; loading ...; fig 9h
Ajiro M, Tang S, Doorbar J, Zheng Z. Serine/Arginine-Rich Splicing Factor 3 and Heterogeneous Nuclear Ribonucleoprotein A1 Regulate Alternative RNA Splicing and Gene Expression of Human Papillomavirus 18 through Two Functionally Distinguishable cis Elements. J Virol. 2016;90:9138-52 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:2000; fig 1
  • western blot; human; 1:2000; fig 1
Park W, Kim H, Kang D, Ryu J, Choi K, Lee G, et al. Comparative expression patterns and diagnostic efficacies of SR splicing factors and HNRNPA1 in gastric and colorectal cancer. BMC Cancer. 2016;16:358 pubmed publisher
  • western blot; human; loading ...; fig 3e
Tang S, Luo S, Ho J, Ly P, Goh E, Roca X. Characterization of the Regulation of CD46 RNA Alternative Splicing. J Biol Chem. 2016;291:14311-23 pubmed publisher
  • cross-linking immunoprecipitation; human; fig 6
  • western blot; human; fig 6
Geissler R, Simkin A, Floss D, Patel R, Fogarty E, Scheller J, et al. A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1. Genes Dev. 2016;30:1070-85 pubmed publisher
  • western blot; human; 1:2000; fig 5
Parameswaran R, Ramakrishnan P, Moreton S, Xia Z, Hou Y, Lee D, et al. Repression of GSK3 restores NK cell cytotoxicity in AML patients. Nat Commun. 2016;7:11154 pubmed publisher
  • RNA immunoprecipitation; human
Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016;61:903-13 pubmed publisher
  • western blot; human; 1:1000
Contreras T, Ricciardi E, Cremonini E, Oteiza P. (-)-Epicatechin in the prevention of tumor necrosis alpha-induced loss of Caco-2 cell barrier integrity. Arch Biochem Biophys. 2015;573:84-91 pubmed publisher
  • RNA immunoprecipitation; human; loading ...; fig 6a
DERY K, Kujawski M, Grunert D, Wu X, Ngyuen T, Cheung C, et al. IRF-1 regulates alternative mRNA splicing of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in breast epithelial cells generating an immunoreceptor tyrosine-based inhibition motif (ITIM) containing isoform. Mol Cancer. 2014;13:64 pubmed publisher
  • immunoprecipitation; human; fig 4
Rust H, Subramanian V, West G, Young D, Schultz P, Thompson P. Using unnatural amino acid mutagenesis to probe the regulation of PRMT1. ACS Chem Biol. 2014;9:649-55 pubmed publisher
Yandrapally S, Sarkar S, Banerjee S. HIV-1 Tat commandeers nuclear export of Rev-viral RNA complex by controlling hnRNPA2-mediated splicing. J Virol. 2023;97:e0104423 pubmed publisher
Jiang Y, Fu X, Zhang Y, Wang S, Zhu H, Wang W, et al. Rett syndrome linked to defects in forming the MeCP2/Rbfox/LASR complex in mouse models. Nat Commun. 2021;12:5767 pubmed publisher
Huh D, Passarelli M, Gao J, Dusmatova S, Goin C, Fish L, et al. A stress-induced tyrosine-tRNA depletion response mediates codon-based translational repression and growth suppression. EMBO J. 2021;40:e106696 pubmed publisher
Kumarasinghe N, Moss W. Analysis of a structured intronic region of the LMP2 pre-mRNA from EBV reveals associations with human regulatory proteins and nuclear actin. BMC Res Notes. 2019;12:33 pubmed publisher
Omer Javed A, Li Y, Muffat J, Su K, Cohen M, Lungjangwa T, et al. Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype. Cell Rep. 2018;25:368-382.e5 pubmed publisher
Yu Z, Tang P, Wang J, Bao S, Shieh J, Leung A, et al. Mutations in Hnrnpa1 cause congenital heart defects. JCI Insight. 2018;3: pubmed publisher
Treiber T, Treiber N, Plessmann U, Harlander S, Daiß J, Eichner N, et al. A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis. Mol Cell. 2017;66:270-284.e13 pubmed publisher
Ajiro M, Jia R, Yang Y, Zhu J, Zheng Z. A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells. Nucleic Acids Res. 2016;44:1854-70 pubmed publisher
Roos M, Rebhan M, Lucic M, Pavlicek D, Pradère U, Towbin H, et al. Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells. Nucleic Acids Res. 2015;43:e9 pubmed publisher
Uranga R, Katz S, Salvador G. Enhanced phosphatidylinositol 3-kinase (PI3K)/Akt signaling has pleiotropic targets in hippocampal neurons exposed to iron-induced oxidative stress. J Biol Chem. 2013;288:19773-84 pubmed publisher
Towbin H, Wenter P, Guennewig B, Imig J, Zagalak J, Gerber A, et al. Systematic screens of proteins binding to synthetic microRNA precursors. Nucleic Acids Res. 2013;41:e47 pubmed publisher
Damiano F, Rochira A, Tocci R, Alemanno S, Gnoni A, Siculella L. hnRNP A1 mediates the activation of the IRES-dependent SREBP-1a mRNA translation in response to endoplasmic reticulum stress. Biochem J. 2013;449:543-53 pubmed publisher
Choi Y, Lim J, Jeong M, Kim K. HnRNP A1 phosphorylated by VRK1 stimulates telomerase and its binding to telomeric DNA sequence. Nucleic Acids Res. 2012;40:8499-518 pubmed
Bonnart C, Gerus M, Hoareau Aveilla C, Kiss T, Caizergues Ferrer M, Henry Y, et al. Mammalian HCA66 protein is required for both ribosome synthesis and centriole duplication. Nucleic Acids Res. 2012;40:6270-89 pubmed publisher
MacKenzie G, Salvador G, Romero C, Keen C, Oteiza P. A deficit in zinc availability can cause alterations in tubulin thiol redox status in cultured neurons and in the developing fetal rat brain. Free Radic Biol Med. 2011;51:480-9 pubmed publisher
Redon S, Reichenbach P, Lingner J. The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase. Nucleic Acids Res. 2010;38:5797-806 pubmed publisher
product information
Catalog Number :
sc-32301
Product Name :
hnRNP A1 (4B10) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
4B10
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
hnRNP A1
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA