product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
α Tubulin (DM1A) Antibody
catalog :
sc-32293
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DM1A
reactivity :
Candida albicans, Trypanosoma cruzi, human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 133
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; loading ...; fig 1c
Ilik I, Malszycki M, Lübke A, Schade C, Meierhofer D, Aktas T. SON and SRRM2 are essential for nuclear speckle formation. elife. 2020;9: pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 5c
Chong W, Wang W, Lo C, Chiu T, Chang T, Liu Y, et al. Super-resolution microscopy reveals coupling between mammalian centriole subdistal appendages and distal appendages. elife. 2020;9: pubmed publisher
  • western blot; mouse; 1:10,000; loading ...; fig 1a
Thomson B, Carota I, Souma T, Soman S, Vestweber D, Quaggin S. Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma. elife. 2019;8: pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 1a
Moriyama M, Koshiba T, Ichinohe T. Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses. Nat Commun. 2019;10:4624 pubmed publisher
  • western blot; human; 1:1000; fig 7
Justa Schuch D, Silva Garcia M, Pilla E, Engelke M, Kilisch M, Lenz C, et al. DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk. elife. 2016;5: pubmed publisher
  • western blot; human; fig 1
Grainger D, Kutzler L, Rannels S, Kimball S. Validation of a commercially available anti-REDD1 antibody using RNA interference and REDD1-/- mouse embryonic fibroblasts. F1000Res. 2016;5:250 pubmed publisher
  • western blot; human; fig 5
Matias A, Manieri T, Cerchiaro G. Zinc Chelation Mediates the Lysosomal Disruption without Intracellular ROS Generation. Oxid Med Cell Longev. 2016;2016:6724585 pubmed publisher
  • western blot; mouse; 1:200; fig 1
Pinz S, Unser S, Rascle A. Signal transducer and activator of transcription STAT5 is recruited to c-Myc super-enhancer. BMC Mol Biol. 2016;17:10 pubmed publisher
  • western blot; mouse; 1:5000; fig 5b
Prieto J, León M, Ponsoda X, Sendra R, Bort R, Ferrer Lorente R, et al. Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming. Nat Commun. 2016;7:11124 pubmed publisher
  • western blot; human; fig 3
Kimball S, Gordon B, Moyer J, Dennis M, Jefferson L. Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation. Cell Signal. 2016;28:896-906 pubmed publisher
  • western blot; mouse; fig 1
  • western blot; human; fig 1
M L, P P, T K, M P, E S, J P, et al. Essential role of HDAC6 in the regulation of PD-L1 in melanoma. Mol Oncol. 2016;10:735-750 pubmed publisher
  • western blot; mouse; fig 7
Waddell D, Duffin P, Haddock A, Triplett V, Saredy J, Kakareka K, et al. Isolation, expression analysis and characterization of NEFA-interacting nuclear protein 30 and RING finger and SPRY domain containing 1 in skeletal muscle. Gene. 2016;576:319-32 pubmed publisher
  • immunocytochemistry; human; fig 3
Asghar A, Lajeunesse A, Dulla K, Combes G, Thebault P, Nigg E, et al. Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation. Nat Commun. 2015;6:8364 pubmed publisher
  • western blot; human; fig 1
Bock F, Tanzer M, Haschka M, Krumschnabel G, Sohm B, Goetsch K, et al. The p53 binding protein PDCD5 is not rate-limiting in DNA damage induced cell death. Sci Rep. 2015;5:11268 pubmed publisher
  • western blot; human; fig 1
García Cano J, Ambroise G, Pascual Serra R, Carrión M, Serrano Oviedo L, Ortega Muelas M, et al. Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance. Oncotarget. 2015;6:15551-65 pubmed
  • western blot; mouse
Woan K, Lienlaf M, Perez Villaroel P, Lee C, Cheng F, Knox T, et al. Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation. Mol Oncol. 2015;9:1447-1457 pubmed publisher
  • western blot; mouse; fig f6
Chung J, Bauer D, Ghamari A, Nizzi C, Deck K, Kingsley P, et al. The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability. Sci Signal. 2015;8:ra34 pubmed publisher
  • western blot; human
Park S, Jeong J, Park Y, Park K, Lee H, Lee N, et al. Disrupted-in-schizophrenia-1 (DISC1) Regulates Endoplasmic Reticulum Calcium Dynamics. Sci Rep. 2015;5:8694 pubmed publisher
  • western blot; human; 1:1000; fig 3
Kushwaha D, O Leary C, Cron K, Deraska P, Zhu K, D Andrea A, et al. USP9X inhibition promotes radiation-induced apoptosis in non-small cell lung cancer cells expressing mid-to-high MCL1. Cancer Biol Ther. 2015;16:392-401 pubmed publisher
  • western blot; human; fig 4c
Kopanic J, Schlingmann B, Koval M, Lau A, Sorgen P, Su V. Degradation of gap junction connexins is regulated by the interaction with Cx43-interacting protein of 75 kDa (CIP75). Biochem J. 2015;466:571-85 pubmed publisher
  • western blot; human; fig 6
Earley L, Kawano Y, Adachi K, Sun X, Dai M, Nakai H. Identification and characterization of nuclear and nucleolar localization signals in the adeno-associated virus serotype 2 assembly-activating protein. J Virol. 2015;89:3038-48 pubmed publisher
  • immunohistochemistry; human; 1:400
Van de Laar E, Clifford M, Hasenoeder S, Kim B, Wang D, Lee S, et al. Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas. Respir Res. 2014;15:160 pubmed publisher
  • immunocytochemistry; Candida albicans; 1:1000; fig 9
Olmsted Z, Colliver A, Riehlman T, Paluh J. Kinesin-14 and kinesin-5 antagonistically regulate microtubule nucleation by γ-TuRC in yeast and human cells. Nat Commun. 2014;5:5339 pubmed publisher
  • immunocytochemistry; Trypanosoma cruzi; 1:100
Díaz Chiguer D, Hernández Luis F, Nogueda Torres B, Castillo R, Reynoso Ducoing O, Hernández Campos A, et al. JVG9, a benzimidazole derivative, alters the surface and cytoskeleton of Trypanosoma cruzi bloodstream trypomastigotes. Mem Inst Oswaldo Cruz. 2014;109:757-60 pubmed
  • western blot; mouse; fig 4
Cheng F, Lienlaf M, Wang H, Perez Villarroel P, Lee C, Woan K, et al. A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs. J Immunol. 2014;193:2850-62 pubmed publisher
  • immunocytochemistry; human
Lee M, Moreno C, Saavedra H. E2F activators signal and maintain centrosome amplification in breast cancer cells. Mol Cell Biol. 2014;34:2581-99 pubmed
  • western blot; human
Pavet V, Shlyakhtina Y, He T, Ceschin D, Kohonen P, Perala M, et al. Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells. Cell Death Dis. 2014;5:e1043 pubmed publisher
  • immunocytochemistry; human
Del Nagro C, Choi J, Xiao Y, Rangell L, Mohan S, Pandita A, et al. Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death. Cell Cycle. 2014;13:303-14 pubmed publisher
  • western blot; human
Gal J, Chen J, Barnett K, Yang L, Brumley E, Zhu H. HDAC6 regulates mutant SOD1 aggregation through two SMIR motifs and tubulin acetylation. J Biol Chem. 2013;288:15035-45 pubmed publisher
Halfmann C, Scott K, Sears R, Roux K. Mechanisms by which barrier-to-autointegration factor regulates dynamics of nucleocytoplasmic leakage and membrane repair following nuclear envelope rupture. bioRxiv. 2023;: pubmed publisher
Sun Y, Dai H, Dai X, Yin J, Cui Y, Liu X, et al. m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration. Nature. 2023;623:580-587 pubmed publisher
Madan V, Albacete Albacete L, Jin L, Scaturro P, Watson J, Muschalik N, et al. HEATR5B associates with dynein-dynactin and promotes motility of AP1-bound endosomal membranes. EMBO J. 2023;42:e114473 pubmed publisher
Shin D, Jo J, Choi M, Kim K, Bae Y, Kim S. Oncogenic KRAS mutation confers chemoresistance by upregulating SIRT1 in non-small cell lung cancer. Exp Mol Med. 2023;55:2220-2237 pubmed publisher
McAloney C, Makkawi R, Budhathoki Y, Cannon M, Franz E, Gross A, et al. Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization. Cell Oncol (Dordr). 2023;: pubmed publisher
Boegholm N, Petriman N, Loureiro L xf3 pez M, Wang J, Vela M, Liu B, et al. The IFT81-IFT74 complex acts as an unconventional RabL2 GTPase-activating protein during intraflagellar transport. EMBO J. 2023;42:e111807 pubmed publisher
Didaskalou S, Efstathiou C, Galtsidis S, Kesisova I, Halavatyi A, Elmali T, et al. HURP localization in metaphase is the result of a multi-step process requiring its phosphorylation at Ser627 residue. Front Cell Dev Biol. 2023;11:981425 pubmed publisher
Gao R, Lv S, Chen A, Huang J, Wang L, Feng Y, et al. Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness. Signal Transduct Target Ther. 2023;8:275 pubmed publisher
Santos C, Rogers S, Carter A. CryoET shows cofilactin filaments inside the microtubule lumen. bioRxiv. 2023;: pubmed publisher
Weigert R, Hetzel S, Bailly N, Haggerty C, Ilik I, Yung P, et al. Dynamic antagonism between key repressive pathways maintains the placental epigenome. Nat Cell Biol. 2023;25:579-591 pubmed publisher
Nieddu V, Melocchi V, Battistini C, Franciosa G, Lupia M, Stellato C, et al. Matrix Gla Protein drives stemness and tumor initiation in ovarian cancer. Cell Death Dis. 2023;14:220 pubmed publisher
Levesque S, Mayorga D, Fiset J, Goupil C, Duringer A, Loiselle A, et al. Marker-free co-selection for successive rounds of prime editing in human cells. Nat Commun. 2022;13:5909 pubmed publisher
Morshneva A, Gnedina O, Kindt D, Igotti M. Ras Participates in the Regulation of the Stability of Adenoviral Protein E1A via MAP-kinase ERK. Acta Naturae. 2022;14:78-84 pubmed publisher
Harigai R, Sato R, Hirose C, Takenouchi T, Kosaki K, Hirose T, et al. Mutation of PTPN11 (Encoding SHP-2) Promotes MEK Activation and Malignant Progression in Neurofibromin-Deficient Cells in a Manner Sensitive to BRAP Mutation. Cancers (Basel). 2022;14: pubmed publisher
Pinto A, Rai R, Brown J, Griffin P, Edgar J, Shah A, et al. Ultrastructural insight into SARS-CoV-2 entry and budding in human airway epithelium. Nat Commun. 2022;13:1609 pubmed publisher
Sears R, Roux K. Mechanisms of A-Type Lamin Targeting to Nuclear Ruptures Are Disrupted in LMNA- and BANF1-Associated Progerias. Cells. 2022;11: pubmed publisher
Shamloul A, Steinemann G, Roos K, Liem C, Bernd J, Braun T, et al. The Methyltransferase Smyd1 Mediates LPS-Triggered Up-Regulation of IL-6 in Endothelial Cells. Cells. 2021;10: pubmed publisher
Del Rio D, Masi I, Caprara V, Spadaro F, Ottavi F, Strippoli R, et al. Ovarian Cancer-Driven Mesothelial-to-Mesenchymal Transition is Triggered by the Endothelin-1/β-arr1 Axis. Front Cell Dev Biol. 2021;9:764375 pubmed publisher
Yamamoto K, Miura H, Ishida M, Mii Y, Kinoshita N, Takada S, et al. Optogenetic relaxation of actomyosin contractility uncovers mechanistic roles of cortical tension during cytokinesis. Nat Commun. 2021;12:7145 pubmed publisher
Jung Y, Artan M, Kim N, Yeom J, Hwang A, Jeong D, et al. MON-2, a Golgi protein, mediates autophagy-dependent longevity in Caenorhabditis elegans. Sci Adv. 2021;7:eabj8156 pubmed publisher
Park H, Hwang W, Ham S, Kim E, Altintas O, Park S, et al. A PTEN variant uncouples longevity from impaired fitness in Caenorhabditis elegans with reduced insulin/IGF-1 signaling. Nat Commun. 2021;12:5631 pubmed publisher
Prieto J, García Cañaveras J, León M, Sendra R, Ponsoda X, Izpisua Belmonte J, et al. c-MYC Triggers Lipid Remodelling During Early Somatic Cell Reprogramming to Pluripotency. Stem Cell Rev Rep. 2021;17:2245-2261 pubmed publisher
Díaz Tejeda Y, Guido Jimenez M, López Carbajal H, Amador Molina A, Méndez Martínez R, Gariglio Vidal P, et al. Nanog, in Cooperation with AP1, Increases the Expression of E6/E7 Oncogenes from HPV Types 16/18. Viruses. 2021;13: pubmed publisher
Lin C, Yang W, Lin Y, Tang X, Chen P, Ding C, et al. DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway. Oncogene. 2021;40:2018-2034 pubmed publisher
Hoffmann M, Mathony J, Upmeier Zu Belzen J, Harteveld Z, Aschenbrenner S, Stengl C, et al. Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein. Nucleic Acids Res. 2021;49:e29 pubmed publisher
Jiménez Gutiérrez G, Mondragón González R, Soto Ponce L, Gómez Monsiváis W, García Aguirre I, Pacheco Rivera R, et al. Loss of Dystroglycan Drives Cellular Senescence via Defective Mitosis-Mediated Genomic Instability. Int J Mol Sci. 2020;21: pubmed publisher
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Chen Z, Zhong H, Wei J, Lin S, Zong Z, Gong F, et al. Inhibition of Nrf2/HO-1 signaling leads to increased activation of the NLRP3 inflammasome in osteoarthritis. Arthritis Res Ther. 2019;21:300 pubmed publisher
Woo Y, Kim S, Suh B, Kwak Y, Jung H, Nhung T, et al. Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis. elife. 2019;8: pubmed publisher
Pal G, Huaman J, Levine F, Orunmuyi A, Olapade Olaopa E, Onagoruwa O, et al. Long Noncoding RNA from PVT1 Exon 9 Is Overexpressed in Prostate Cancer and Induces Malignant Transformation and Castration Resistance in Prostate Epithelial Cells. Genes (Basel). 2019;10: pubmed publisher
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Rezey A, Gerlach B, Wang R, Liao G, Tang D. Plk1 Mediates Paxillin Phosphorylation (Ser-272), Centrosome Maturation, and Airway Smooth Muscle Layer Thickening in Allergic Asthma. Sci Rep. 2019;9:7555 pubmed publisher
Arceci A, Bonacci T, Wang X, Stewart K, Damrauer J, Hoadley K, et al. FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer. Cell Rep. 2019;26:3076-3086.e6 pubmed publisher
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Wu K, Oberstein A, Wang W, Shenk T. Role of PDGF receptor-α during human cytomegalovirus entry into fibroblasts. Proc Natl Acad Sci U S A. 2018;115:E9889-E9898 pubmed publisher
Wang M, Yang W, Chen Y, Wang J, Tan J, Qiao W. Cellular RelB interacts with the transactivator Tat and enhance HIV-1 expression. Retrovirology. 2018;15:65 pubmed publisher
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Kawakami Y, Kurihara Y, Saito Y, Fujita Y, Yamashita T, Takei K. The Soluble Form of LOTUS inhibits Nogo Receptor-Mediated Signaling by Interfering with the Interaction Between Nogo Receptor Type 1 and p75 Neurotrophin Receptor. J Neurosci. 2018;38:2589-2604 pubmed publisher
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Michl C, Vivarelli F, Weigl J, De Nicola G, Canistro D, Paolini M, et al. The Chemopreventive Phytochemical Moringin Isolated from Moringa oleifera Seeds Inhibits JAK/STAT Signaling. PLoS ONE. 2016;11:e0157430 pubmed publisher
Trairatphisan P, Wiesinger M, Bahlawane C, Haan S, Sauter T. A Probabilistic Boolean Network Approach for the Analysis of Cancer-Specific Signalling: A Case Study of Deregulated PDGF Signalling in GIST. PLoS ONE. 2016;11:e0156223 pubmed publisher
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Jensen H, Pedersen H, Stenkjær E, Pedersen G, Login F, Nejsum L. Tir Is Essential for the Recruitment of Tks5 to Enteropathogenic Escherichia coli Pedestals. PLoS ONE. 2015;10:e0141871 pubmed publisher
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Tuckow A, Kazi A, Kimball S, Jefferson L. Identification of ubiquitin-modified lysine residues and novel phosphorylation sites on eukaryotic initiation factor 2B epsilon. Biochem Biophys Res Commun. 2013;436:41-6 pubmed publisher
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Tischner D, Manzl C, Soratroi C, Villunger A, Krumschnabel G. Necrosis-like death can engage multiple pro-apoptotic Bcl-2 protein family members. Apoptosis. 2012;17:1197-1209 pubmed publisher
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product information
Catalog Number :
sc-32293
Product Name :
α Tubulin (DM1A) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
DM1A
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
alpha Tubulin
Specificity :
mouse, rat, human, avian
Uses :
WB, IP, IF, IHC(P)
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA