product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Tau (Tau 46) Antibody
catalog :
sc-32274
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Tau 46
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; loading ...; fig 8b
Qu X, Yuan F, Corona C, Pasini S, Pero M, Gundersen G, et al. Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ1-42 synaptotoxicity. J Cell Biol. 2017;216:3161-3178 pubmed publisher
  • ELISA; mouse; fig 2a
Nobuhara C, DeVos S, Commins C, Wegmann S, Moore B, Roe A, et al. Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro. Am J Pathol. 2017;187:1399-1412 pubmed publisher
  • western blot; mouse; loading ...; fig 6a
Dinkins M, Enasko J, Hernandez C, Wang G, Kong J, Helwa I, et al. Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse. J Neurosci. 2016;36:8653-67 pubmed publisher
Peris L, Parato J, Qu X, Soleilhac J, Lanté F, Kumar A, et al. Tubulin tyrosination regulates synaptic function and is disrupted in Alzheimer's disease. Brain. 2022;: pubmed publisher
Ikezu S, Ingraham Dixie K, Koro L, Watanabe T, Kaibuchi K, Ikezu T. Tau-tubulin kinase 1 and amyloid-β peptide induce phosphorylation of collapsin response mediator protein-2 and enhance neurite degeneration in Alzheimer disease mouse models. Acta Neuropathol Commun. 2020;8:12 pubmed publisher
Ko H, Chiou S, Wong Y, Wang Y, Lai Y, Chou C, et al. GSKIP-Mediated Anchoring Increases Phosphorylation of Tau by PKA but Not by GSK3beta via cAMP/PKA/GSKIP/GSK3/Tau Axis Signaling in Cerebrospinal Fluid and iPS Cells in Alzheimer Disease. J Clin Med. 2019;8: pubmed publisher
Oka M, Fujisaki N, Maruko Otake A, Ohtake Y, Shimizu S, Saito T, et al. Ca2+/calmodulin-dependent protein kinase II promotes neurodegeneration caused by tau phosphorylated at Ser262/356 in a transgenic Drosophila model of tauopathy. J Biochem. 2017;162:335-342 pubmed publisher
Zhang R, Xu J, Liu Y, Zuo P, Yang N, Ji C, et al. Propofol may protect PC12 cells from ?-amyloid????? induced apoptosis through the GSK-3? signaling pathway. Chin Med J (Engl). 2013;126:1884-9 pubmed
Qu X, Xu C, Wang H, Xu J, Liu W, Wang Y, et al. Hippocampal glutamate level and glutamate aspartate transporter (GLAST) are up-regulated in senior rat associated with isoflurane-induced spatial learning/memory impairment. Neurochem Res. 2013;38:59-73 pubmed publisher
Xu J, Zhang R, Zuo P, Yang N, Ji C, Liu W, et al. Aggravation effect of isoflurane on A?(25-35)-induced apoptosis and tau hyperphosphorylation in PC12 cells. Cell Mol Neurobiol. 2012;32:1343-51 pubmed publisher
Avsar T, Korkmaz D, Tutuncu M, Demirci N, Saip S, Kamasak M, et al. Protein biomarkers for multiple sclerosis: semi-quantitative analysis of cerebrospinal fluid candidate protein biomarkers in different forms of multiple sclerosis. Mult Scler. 2012;18:1081-91 pubmed publisher
Liu W, Xu J, Wang H, Xu C, Ji C, Wang Y, et al. Isoflurane-induced spatial memory impairment by a mechanism independent of amyloid-beta levels and tau protein phosphorylation changes in aged rats. Neurol Res. 2012;34:3-10 pubmed publisher
Chen L, Wang Y, Tseng G. Compression alters kinase and phosphatase activity and tau and MAP2 phosphorylation transiently while inducing the fast adaptive dendritic remodeling of underlying cortical neurons. J Neurotrauma. 2010;27:1657-69 pubmed publisher
product information
Catalog Number :
sc-32274
Product Name :
Tau (Tau 46) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
Tau 46
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Tau
Specificity :
mouse, rat, human
Uses :
WB, IP, IF
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA