product summary
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company name :
Santa Cruz Biotechnology
product type :
gene knockdown
product name :
Met siRNA (h)
catalog :
sc-29397
quantity :
10 µM
price :
293 USD
citations: 9
Reference
Zhu K, Lv Z, Xiong J, Zheng H, Zhang S, Jin H, et al. MET inhibitor, capmatinib overcomes osimertinib resistance via suppression of MET/Akt/snail signaling in non-small cell lung cancer and decreased generation of cancer-associated fibroblasts. Aging (Albany NY). 2021;13:6890-6903 pubmed publisher
Majidi Zolbanin N, Jafari R, Majidi J, Atyabi F, Yousefi M, Jadidi Niaragh F, et al. Targeted Co-Delivery of Docetaxel and cMET siRNA for Treatment of Mucin1 Overexpressing Breast Cancer Cells. Adv Pharm Bull. 2018;8:383-393 pubmed publisher
Kumar D, New J, Vishwakarma V, Joshi R, Enders J, Lin F, et al. Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression. Cancer Res. 2018;78:3769-3782 pubmed publisher
Du S, Wang S, Wu Q, Hu J, Li T. Decorin inhibits angiogenic potential of choroid-retinal endothelial cells by downregulating hypoxia-induced Met, Rac1, HIF-1? and VEGF expression in cocultured retinal pigment epithelial cells. Exp Eye Res. 2013;116:151-60 pubmed publisher
Velpula K, Dasari V, Asuthkar S, Gorantla B, Tsung A. EGFR and c-Met Cross Talk in Glioblastoma and Its Regulation by Human Cord Blood Stem Cells. Transl Oncol. 2012;5:379-92 pubmed
Buraschi S, Pal N, Tyler Rubinstein N, Owens R, Neill T, Iozzo R. Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels. J Biol Chem. 2010;285:42075-85 pubmed publisher
Bu R, Uddin S, Bavi P, Hussain A, Al Dayel F, Ghourab S, et al. HGF/c-Met pathway has a prominent role in mediating antiapoptotic signals through AKT in epithelial ovarian carcinoma. Lab Invest. 2011;91:124-37 pubmed publisher
Welsh J, Mahadevan D, Ellsworth R, Cooke L, Bearss D, Stea B. The c-Met receptor tyrosine kinase inhibitor MP470 radiosensitizes glioblastoma cells. Radiat Oncol. 2009;4:69 pubmed publisher
Mukhopadhyay I, Sausville E, Doroshow J, Roy K. Molecular mechanism of adaphostin-mediated G1 arrest in prostate cancer (PC-3) cells: signaling events mediated by hepatocyte growth factor receptor, c-Met, and p38 MAPK pathways. J Biol Chem. 2006;281:37330-44 pubmed
product information
Catalog Number :
sc-29397
Product Name :
Met siRNA (h)
Product Type :
siRNA
Size :
10 µM
List Price :
293 USD
Immunogen :
Met
Specificity :
human
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA