product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
TLR4
catalog :
sc-293072
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
25
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 25
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:500; loading ...; fig 1d
Lindfors S, Polianskyte Prause Z, Bouslama R, Lehtonen E, Mannerla M, Nisen H, et al. Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo. Diabetologia. 2021;64:1866-1879 pubmed publisher
  • western blot; human; 1:200; loading ...; fig 3f
Loureiro J, Raimundo L, Calheiros J, Carvalho C, Barcherini V, Lima N, et al. Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance. Cancers (Basel). 2021;13: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 7
Sun Y, Wu D, Zeng W, Chen Y, Guo M, Lu B, et al. The Role of Intestinal Dysbacteriosis Induced Arachidonic Acid Metabolism Disorder in Inflammaging in Atherosclerosis. Front Cell Infect Microbiol. 2021;11:618265 pubmed publisher
  • western blot; mouse; fig 3b
Watahiki A, Hoshikawa S, Chiba M, Egusa H, Fukumoto S, Inuzuka H. Deficiency of Lipin2 Results in Enhanced NF-κB Signaling and Osteoclast Formation in RAW-D Murine Macrophages. Int J Mol Sci. 2021;22: pubmed publisher
  • western blot; human; loading ...; fig 7a
Iannucci A, Caneparo V, Raviola S, Debernardi I, Colangelo D, Miggiano R, et al. Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced by lipopolysaccharide binding. PLoS Pathog. 2020;16:e1008811 pubmed publisher
  • western blot; mouse; 1:300; loading ...; fig s4b
Duan X, Liu X, Liu N, Huang Y, Jin Z, Zhang S, et al. Inhibition of keratinocyte necroptosis mediated by RIPK1/RIPK3/MLKL provides a protective effect against psoriatic inflammation. Cell Death Dis. 2020;11:134 pubmed publisher
  • immunohistochemistry - paraffin section; dogs; 1:500; loading ...; fig 1
von Rüden E, Gualtieri F, Schönhoff K, Reiber M, Wolf F, Baumgartner W, et al. Molecular alterations of the TLR4-signaling cascade in canine epilepsy. BMC Vet Res. 2020;16:18 pubmed publisher
  • western blot; human; 1:500; loading ...; fig s3a
Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, et al. Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation. Nat Immunol. 2020;21:30-41 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 8b
Lu Y, Kim N, Jiang Y, Zhang H, Zheng D, Zhu F, et al. Cambogin suppresses dextran sulphate sodium-induced colitis by enhancing Treg cell stability and function. Br J Pharmacol. 2018;175:1085-1099 pubmed publisher
  • immunoprecipitation; rat; 1:100; loading ...; fig 7
  • western blot; rat; 1:50; loading ...; fig 6
Chen X, Tang L, Fu Y, Wang Y, Han Z, Meng J. Paralemmin-3 contributes to lipopolysaccharide-induced inflammatory response and is involved in lipopolysaccharide-Toll-like receptor-4 signaling in alveolar macrophages. Int J Mol Med. 2017;40:1921-1931 pubmed publisher
Li X, Huang R, Liu K, Li M, Luo H, Cui L, et al. Fucoxanthin attenuates LPS-induced acute lung injury via inhibition of the TLR4/MyD88 signaling axis. Aging (Albany NY). 2020;13:2655-2667 pubmed publisher
Zhang X, Zhang Y, Li R, Zhu L, Fu B, Yan T. Salidroside ameliorates Parkinson's disease by inhibiting NLRP3-dependent pyroptosis. Aging (Albany NY). 2020;12:9405-9426 pubmed publisher
Chang G, Zhang H, Wang Y, Ma N, Chandra R, Ye G, et al. Microbial community shifts elicit inflammation in the caecal mucosa via the GPR41/43 signalling pathway during subacute ruminal acidosis. BMC Vet Res. 2019;15:298 pubmed publisher
Huang C, Yang X, Huang J, Liu X, Yang X, Jin H, et al. Porcine Beta-Defensin 2 Provides Protection Against Bacterial Infection by a Direct Bactericidal Activity and Alleviates Inflammation via Interference With the TLR4/NF-κB Pathway. Front Immunol. 2019;10:1673 pubmed publisher
Menden H, Xia S, Mabry S, Noel MacDonnell J, Rajasingh J, Qing Ye S, et al. Histone Deacetylase 6 Regulates Endothelial MyD88-dependent canonical TLR signaling, Lung inflammation, and Alveolar Remodeling in the developing lung. Am J Physiol Lung Cell Mol Physiol. 2019;: pubmed publisher
Jia Y, Zheng Z, Xue M, Zhang S, Hu F, Li Y, et al. Extracellular Vesicles from Albumin-Induced Tubular Epithelial Cells Promote the M1 Macrophage Phenotype by Targeting Klotho. Mol Ther. 2019;: pubmed publisher
Zhang L, Yang Z, Huang W, Wu J. H19 potentiates let-7 family expression through reducing PTBP1 binding to their precursors in cholestasis. Cell Death Dis. 2019;10:168 pubmed publisher
Lv X, Wang H, Su A, Xu S, Chu Y. Herpes simplex virus type 2 infection triggers AP-1 transcription activity through TLR4 signaling in genital epithelial cells. Virol J. 2018;15:173 pubmed publisher
Gong H, Su W, Cao Z, Lian Y, Peng W, Liu Y, et al. Hippocampal Mrp8/14 signaling plays a critical role in the manifestation of depressive-like behaviors in mice. J Neuroinflammation. 2018;15:252 pubmed publisher
Xiang W, Shi R, Kang X, Zhang X, Chen P, Zhang L, et al. Monoacylglycerol lipase regulates cannabinoid receptor 2-dependent macrophage activation and cancer progression. Nat Commun. 2018;9:2574 pubmed publisher
Balan I, Warnock K, Puche A, GONDRE LEWIS M, JUNE H, Aurelian L. The GABAA Receptor α2 Subunit Activates a Neuronal TLR4 Signal in the Ventral Tegmental Area that Regulates Alcohol and Nicotine Abuse. Brain Sci. 2018;8: pubmed publisher
Xu Q, Bo L, Hu J, Geng J, Chen Y, Li X, et al. High mobility group box 1 was associated with thrombosis in patients with atrial fibrillation. Medicine (Baltimore). 2018;97:e0132 pubmed publisher
Gao J, Meng X, Zhang J, Chen W, Xia F, Peng K, et al. Dexmedetomidine Protects Cardiomyocytes against Hypoxia/Reoxygenation Injury by Suppressing TLR4-MyD88-NF-κB Signaling. Biomed Res Int. 2017;2017:1674613 pubmed publisher
Iampietro M, Younan P, Nishida A, Dutta M, Lubaki N, Santos R, et al. Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection. PLoS Pathog. 2017;13:e1006397 pubmed publisher
Shen Y, Qin H, Chen J, Mou L, He Y, Yan Y, et al. Postnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons. J Cell Biol. 2016;215:719-734 pubmed
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA