| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; human; loading ...; fig 3h
| Lafave L, Beguelin W, Koche R, Teater M, Spitzer B, Chramiec A, et al. Loss of BAP1 function leads to EZH2-dependent transformation. Nat Med. 2015;21:1344-9 pubmed publisher |
- western blot; rat; loading ...
| Kong Y, Akatsuka S, Motooka Y, Zheng H, Cheng Z, Shiraki Y, et al. BRCA1 haploinsufficiency promotes chromosomal amplification under Fenton reaction-based carcinogenesis through ferroptosis-resistance. Redox Biol. 2022;54:102356 pubmed publisher |
- western blot; human; 1:1000; fig 2
| Mergener S, Siveke J, Peña Llopis S. Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma. Int J Mol Sci. 2021;22: pubmed publisher |
- western blot; human; 1:2000; loading ...; fig s5g
| Perkail S, Andricovich J, Kai Y, Tzatsos A. BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice. Nat Commun. 2020;11:3018 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 1a
| Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, et al. BAP1 links metabolic regulation of ferroptosis to tumour suppression. Nat Cell Biol. 2018;20:1181-1192 pubmed publisher |
- other; human; loading ...; fig 4c
| Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher |
- western blot; human; loading ...; fig 1d
| Bononi A, Giorgi C, Patergnani S, Larson D, Verbruggen K, Tanji M, et al. BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation. Nature. 2017;546:549-553 pubmed publisher |
- reverse phase protein lysate microarray; human; loading ...; fig st6
| Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher |
- reverse phase protein lysate microarray; human; loading ...; fig 3a
| . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher |
- immunohistochemistry; human; loading ...; tbl 2
| Wu L, Allo G, John T, Li M, Tagawa T, Opitz I, et al. Patient-Derived Xenograft Establishment from Human Malignant Pleural Mesothelioma. Clin Cancer Res. 2017;23:1060-1067 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:200; fig 1
| Tayao M, Andrici J, Farzin M, Clarkson A, Sioson L, Watson N, et al. Loss of BAP1 Expression Is Very Rare in Pancreatic Ductal Adenocarcinoma. PLoS ONE. 2016;11:e0150338 pubmed publisher |
- immunohistochemistry - free floating section; human; 1:50; fig s3
| Ho T, Kapur P, Joseph R, Serie D, Eckel Passow J, Tong P, et al. Loss of histone H3 lysine 36 trimethylation is associated with an increased risk of renal cell carcinoma-specific death. Mod Pathol. 2016;29:34-42 pubmed publisher |
- immunoprecipitation; human; fig 3
- immunocytochemistry; human; fig 3
- western blot; human; fig 6
| Qin J, Zhou Z, Chen W, Wang C, Zhang H, Ge G, et al. BAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5. Nat Commun. 2015;6:8471 pubmed publisher |
- immunoprecipitation; human; fig 1b
| Daou S, Hammond Martel I, Mashtalir N, Barbour H, Gagnon J, Iannantuono N, et al. The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer. J Biol Chem. 2015;290:28643-63 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; fig 5
- immunoprecipitation; human; fig 2
- western blot; human; fig 2
| Mori T, Sumii M, Fujishima F, Ueno K, Emi M, Nagasaki M, et al. Somatic alteration and depleted nuclear expression of BAP1 in human esophageal squamous cell carcinoma. Cancer Sci. 2015;106:1118-29 pubmed publisher |
- western blot; human; fig 3a
| Gagnon J, Daou S, Zamorano N, Iannantuono N, Hammond Martel I, Mashtalir N, et al. Undetectable histone O-GlcNAcylation in mammalian cells. Epigenetics. 2015;10:677-91 pubmed publisher |
- immunohistochemistry; human; 1:50
| Ho T, Kapur P, Joseph R, Serie D, Eckel Passow J, Parasramka M, et al. Loss of PBRM1 and BAP1 expression is less common in non-clear cell renal cell carcinoma than in clear cell renal cell carcinoma. Urol Oncol. 2015;33:23.e9-23.e14 pubmed publisher |
- chromatin immunoprecipitation; human
- immunoprecipitation; human
- immunocytochemistry; human; fig 2c
- western blot; human
| Ji Z, Mohammed H, Webber A, Ridsdale J, Han N, Carroll J, et al. The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex. Nucleic Acids Res. 2014;42:6232-42 pubmed publisher |
| Singh A, Busacca S, Gaba A, Sheaff M, Poile C, Nakas A, et al. BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms. Oncogene. 2022;: pubmed publisher |
| Kaler C, Dollar J, Cruz A, Kuznetsoff J, Sanchez M, Decatur C, et al. BAP1 Loss Promotes Suppressive Tumor Immune Microenvironment via Upregulation of PROS1 in Class 2 Uveal Melanomas. Cancers (Basel). 2022;14: pubmed publisher |
| Yang T, Li T, Huang R, Pan M, Lin S, Lin S, et al. Tumor suppressor BAP1 nuclear import is governed by transportin-1. J Cell Biol. 2022;221: pubmed publisher |
| Jiang H, Mei Y. SARS-CoV-2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro. Viruses. 2021;13: pubmed publisher |
| Bakhoum M, Francis J, Agustinus A, Earlie E, Di Bona M, Abramson D, et al. Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression. Nat Commun. 2021;12:5402 pubmed publisher |
| Fujino T, Goyama S, Sugiura Y, Inoue D, Asada S, Yamasaki S, et al. Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway. Nat Commun. 2021;12:1826 pubmed publisher |
| Makhov P, Sohn J, Serebriiskii I, Fazliyeva R, Khazak V, Boumber Y, et al. CRISPR/Cas9 genome-wide loss-of-function screening identifies druggable cellular factors involved in sunitinib resistance in renal cell carcinoma. Br J Cancer. 2020;123:1749-1756 pubmed publisher |
| Zhang Y, Koppula P, Gan B. Regulation of H2A ubiquitination and SLC7A11 expression by BAP1 and PRC1. Cell Cycle. 2019;18:773-783 pubmed publisher |
| Rose A, Luo R, Radia U, Kalirai H, Thornton S, Luthert P, et al. Detection of mutations in SF3B1, EIF1AX and GNAQ in primary orbital melanoma by candidate gene analysis. BMC Cancer. 2018;18:1262 pubmed publisher |
| Liao L, Liu Z, Langbein L, Cai W, Cho E, Na J, et al. Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer. elife. 2018;7: pubmed publisher |
| Yuan J, Ma Y, Huang T, Chen Y, Peng Y, Li B, et al. Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase. Mol Cell. 2018;72:380-394.e7 pubmed publisher |
| Rehrauer H, Wu L, Blum W, Pecze L, Henzi T, Serre Beinier V, et al. How asbestos drives the tissue towards tumors: YAP activation, macrophage and mesothelial precursor recruitment, RNA editing, and somatic mutations. Oncogene. 2018;37:2645-2659 pubmed publisher |
| Kolluri K, Alifrangis C, Kumar N, Ishii Y, Price S, Michaut M, et al. Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells. elife. 2018;7: pubmed publisher |
| Vader M, Madigan M, Versluis M, Suleiman H, Gezgin G, Gruis N, et al. GNAQ and GNA11 mutations and downstream YAP activation in choroidal nevi. Br J Cancer. 2017;117:884-887 pubmed publisher |
| Parasramka M, Yan I, Wang X, Nguyen P, Matsuda A, Maji S, et al. BAP1 dependent expression of long non-coding RNA NEAT-1 contributes to sensitivity to gemcitabine in cholangiocarcinoma. Mol Cancer. 2017;16:22 pubmed publisher |
| Andrici J, Sheen A, Sioson L, Wardell K, Clarkson A, Watson N, et al. Loss of expression of BAP1 is a useful adjunct, which strongly supports the diagnosis of mesothelioma in effusion cytology. Mod Pathol. 2015;28:1360-8 pubmed publisher |
| Hakiri S, Osada H, Ishiguro F, Murakami H, Murakami Tonami Y, Yokoi K, et al. Functional differences between wild-type and mutant-type BRCA1-associated protein 1 tumor suppressor against malignant mesothelioma cells. Cancer Sci. 2015;106:990-9 pubmed publisher |
| Arzt L, Quehenberger F, Halbwedl I, Mairinger T, Popper H. BAP1 protein is a progression factor in malignant pleural mesothelioma. Pathol Oncol Res. 2014;20:145-51 pubmed publisher |
| Popova T, Hebert L, Jacquemin V, Gad S, Caux Moncoutier V, Dubois d Enghien C, et al. Germline BAP1 mutations predispose to renal cell carcinomas. Am J Hum Genet. 2013;92:974-80 pubmed publisher |
| Yoshikawa Y, Sato A, Tsujimura T, Emi M, Morinaga T, Fukuoka K, et al. Frequent inactivation of the BAP1 gene in epithelioid-type malignant mesothelioma. Cancer Sci. 2012;103:868-74 pubmed publisher |
| Bott M, Brevet M, Taylor B, Shimizu S, Ito T, Wang L, et al. The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma. Nat Genet. 2011;43:668-72 pubmed publisher |
