product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Polycystin-2 (D-3) Antibody
catalog :
sc-28331
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D-3
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:100; loading ...; fig 1a
MacKay C, Leo M, Fernández Peña C, Hasan R, Yin W, Mata Daboin A, et al. Intravascular flow stimulates PKD2 (polycystin-2) channels in endothelial cells to reduce blood pressure. elife. 2020;9: pubmed publisher
  • immunocytochemistry; mouse; 1:300; loading ...; fig 7a
Yu F, Sharma S, Skowronek A, Erdmann K. The serologically defined colon cancer antigen-3 (SDCCAG3) is involved in the regulation of ciliogenesis. Sci Rep. 2016;6:35399 pubmed publisher
  • immunoprecipitation; mouse; fig 2
  • western blot; mouse; fig 2
Wodarczyk C, Rowe I, Chiaravalli M, Pema M, Qian F, Boletta A. A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus. PLoS ONE. 2009;4:e7137 pubmed publisher
Padhy B, Xie J, Wang R, Lin F, Huang C. Channel Function of Polycystin-2 in the Endoplasmic Reticulum Protects against Autosomal Dominant Polycystic Kidney Disease. J Am Soc Nephrol. 2022;33:1501-1516 pubmed publisher
Márquez Nogueras K, Vuchkovska V, DiNello E, Osorio Valencia S, Kuo I. Polycystin-2 (PC2) is a key determinant of in-vitro myogenesis. Am J Physiol Cell Physiol. 2022;: pubmed publisher
Decuypere J, Van Giel D, Janssens P, Dong K, Somlo S, Cai Y, et al. Interdependent Regulation of Polycystin Expression Influences Starvation-Induced Autophagy and Cell Death. Int J Mol Sci. 2021;22: pubmed publisher
Yanda M, Liu Q, Cebotaru L. A potential strategy for reducing cysts in autosomal dominant polycystic kidney disease with a CFTR corrector. J Biol Chem. 2018;293:11513-11526 pubmed publisher
Pema M, Drusian L, Chiaravalli M, Castelli M, Yao Q, Ricciardi S, et al. mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex. Nat Commun. 2016;7:10786 pubmed publisher
Dalagiorgou G, Piperi C, Georgopoulou U, Adamopoulos C, Basdra E, Papavassiliou A. Mechanical stimulation of polycystin-1 induces human osteoblastic gene expression via potentiation of the calcineurin/NFAT signaling axis. Cell Mol Life Sci. 2013;70:167-180 pubmed publisher
Sammels E, Devogelaere B, Mekahli D, Bultynck G, Missiaen L, Parys J, et al. Polycystin-2 activation by inositol 1,4,5-trisphosphate-induced Ca2+ release requires its direct association with the inositol 1,4,5-trisphosphate receptor in a signaling microdomain. J Biol Chem. 2010;285:18794-805 pubmed publisher
product information
Catalog Number :
sc-28331
Product Name :
Polycystin-2 (D-3) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
D-3
Isotype :
IgG2b
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
Polycystin-2
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA