product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
EWS (G-5) Antibody
catalog :
sc-28327
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G-5
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation, immunocytochemistry knockout validation
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry knockout validation; mouse; fig 2
  • western blot knockout validation; mouse; fig 1
Kim Y, Kang Y, Lee N, Kim K, Hwang Y, Kim H, et al. Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency. Autophagy. 2015;11:796-811 pubmed publisher
  • western blot; human; 1:1000; fig 2
Link S, Grund S, Diederichs S. Alternative splicing affects the subcellular localization of Drosha. Nucleic Acids Res. 2016;44:5330-43 pubmed publisher
Greulich B, Rajendran S, Downing N, Nicholas T, Hollenhorst P. A complex with poly(A)-binding protein and EWS facilitates the transcriptional function of oncogenic ETS transcription factors in prostate cells. J Biol Chem. 2023;299:105453 pubmed publisher
Nicholas T, Metcalf S, Greulich B, Hollenhorst P. Androgen signaling connects short isoform production to breakpoint formation at Ewing sarcoma breakpoint region 1. NAR Cancer. 2021;3:zcab033 pubmed publisher
Baron D, Matheny T, Lin Y, Leszyk J, Kenna K, Gall K, et al. Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS. Hum Mol Genet. 2019;: pubmed publisher
Kedage V, Strittmatter B, Dausinas P, Hollenhorst P. Phosphorylation of the oncogenic transcription factor ERG in prostate cells dissociates polycomb repressive complex 2, allowing target gene activation. J Biol Chem. 2017;292:17225-17235 pubmed publisher
Kedage V, Selvaraj N, Nicholas T, Budka J, Plotnik J, Jerde T, et al. An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer. Cell Rep. 2016;17:1289-1301 pubmed publisher
Nieto Soler M, Morgado Palacin I, Lafarga V, Lecona E, Murga M, Callen E, et al. Efficacy of ATR inhibitors as single agents in Ewing sarcoma. Oncotarget. 2016;7:58759-58767 pubmed publisher
Suárez Calvet M, Neumann M, Arzberger T, Abou Ajram C, Funk E, Hartmann H, et al. Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS. Acta Neuropathol. 2016;131:587-604 pubmed publisher
Ward C, Boggio K, Johnson B, Boyd J, Douthwright S, Shaffer S, et al. A loss of FUS/TLS function leads to impaired cellular proliferation. Cell Death Dis. 2014;5:e1572 pubmed publisher
Davidson Y, Robinson A, Hu Q, Mishra M, Baborie A, Jaros E, et al. Nuclear carrier and RNA-binding proteins in frontotemporal lobar degeneration associated with fused in sarcoma (FUS) pathological changes. Neuropathol Appl Neurobiol. 2013;39:157-65 pubmed publisher
Grund S, Polycarpou Schwarz M, Luo C, Eichmüller S, Diederichs S. Rare Drosha splice variants are deficient in microRNA processing but do not affect general microRNA expression in cancer cells. Neoplasia. 2012;14:238-48 pubmed
product information
Catalog Number :
sc-28327
Product Name :
EWS (G-5) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
G-5
Isotype :
IgG1
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
EWS
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA