product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
TrxR1 (B-2) Antibody
catalog :
sc-28321
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-2
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 16
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
Lou M, Liu Q, Ren G, Zeng J, Xiang X, Ding Y, et al. Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy. J Biol Chem. 2017;292:9136-9149 pubmed publisher
  • western blot; human; 1:1000
Ozdemirler Erata G, Kucukgergin C, Aktan G, Kadioglu A, Uysal M, Kocak Toker N. Is thioredoxin reductase involved in the defense against DNA fragmentation in varicocele?. Asian J Androl. 2013;15:518-22 pubmed publisher
Li Z, Ferguson L, Deol K, Roberts M, Magtanong L, Hendricks J, et al. Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability. Nat Chem Biol. 2022;18:751-761 pubmed publisher
Zhuge W, Chen R, Vladimir K, Dong X, Zia K, Sun X, et al. Costunolide specifically binds and inhibits thioredoxin reductase 1 to induce apoptosis in colon cancer. Cancer Lett. 2018;412:46-58 pubmed publisher
Pei J, Fu W, Yang L, Zhang Z, Liu Y. Oxidative stress is involved in the pathogenesis of Keshan disease (an endemic dilated cardiomyopathy) in China. Oxid Med Cell Longev. 2013;2013:474203 pubmed publisher
Liu Y, Lin D, Xiao T, Ma Y, Hu Z, Zheng H, et al. An immunohistochemical analysis-based decision tree model for estimating the risk of lymphatic metastasis in pN0 squamous cell carcinomas of the lung. Histopathology. 2011;59:882-91 pubmed publisher
Yu J, Shan Z, Chong W, Mao J, Geng Y, Zhang C, et al. Vitamin E ameliorates iodine-induced cytotoxicity in thyroid. J Endocrinol. 2011;209:299-306 pubmed publisher
Issaeva I, Cohen A, Eden E, Cohen Saidon C, Danon T, Cohen L, et al. Generation of double-labeled reporter cell lines for studying co-dynamics of endogenous proteins in individual human cells. PLoS ONE. 2010;5:e13524 pubmed publisher
Rock C, Moos P. Selenoprotein P protects cells from lipid hydroperoxides generated by 15-LOX-1. Prostaglandins Leukot Essent Fatty Acids. 2010;83:203-10 pubmed publisher
Dammeyer P, Arner E. Human Protein Atlas of redox systems - what can be learnt?. Biochim Biophys Acta. 2011;1810:111-38 pubmed publisher
Zhao H, Kim G, Liu C, Levine R. Transgenic mice overexpressing methionine sulfoxide reductase A: characterization of embryonic fibroblasts. Free Radic Biol Med. 2010;49:641-8 pubmed publisher
Rao A, Ziegler Y, McLeod I, Yates J, Nardulli A. Thioredoxin and thioredoxin reductase influence estrogen receptor alpha-mediated gene expression in human breast cancer cells. J Mol Endocrinol. 2009;43:251-61 pubmed publisher
Lam J, Chow K, Xu A, Lam K, Liu J, Wong N, et al. Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities. PLoS ONE. 2009;4:e4968 pubmed publisher
Michard Q, Commo S, Rocchetti J, El Houari F, Alleaume A, Wakamatsu K, et al. TRP-2 expression protects HEK cells from dopamine- and hydroquinone-induced toxicity. Free Radic Biol Med. 2008;45:1002-10 pubmed publisher
Dammeyer P, Damdimopoulos A, Nordman T, Jimenez A, Miranda Vizuete A, Arner E. Induction of cell membrane protrusions by the N-terminal glutaredoxin domain of a rare splice variant of human thioredoxin reductase 1. J Biol Chem. 2008;283:2814-21 pubmed
Sen A, Chatterjee N, Akbar M, Nandi N, Das P. The 29-kilodalton thiol-dependent peroxidase of Entamoeba histolytica is a factor involved in pathogenesis and survival of the parasite during oxidative stress. Eukaryot Cell. 2007;6:664-73 pubmed
product information
Catalog Number :
sc-28321
Product Name :
TrxR1 (B-2) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
B-2
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
TrxR1
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, IHC(P), ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA