product summary
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company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
ZEB2 (E-11) Antibody
catalog :
sc-271984
quantity :
200 µg/ml
price :
316 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
E-11
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 6b
Zhou S, da Silva S, Siegel P, Philip A. CD109 acts as a gatekeeper of the epithelial trait by suppressing epithelial to mesenchymal transition in squamous cell carcinoma cells in vitro. Sci Rep. 2019;9:16317 pubmed publisher
  • western blot; human; loading ...; fig 3b
Vl kov K, Vachtenheim J, R da J, Hor k P, Ondru ov L. Inducibly decreased MITF levels do not affect proliferation and phenotype switching but reduce differentiation of melanoma cells. J Cell Mol Med. 2018;22:2240-2251 pubmed publisher
  • western blot; human; fig 1i
Zhang L, Liu H, Mu X, Cui J, Peng Z. Dysregulation of Fra1 expression by Wnt/β-catenin signalling promotes glioma aggressiveness through epithelial-mesenchymal transition. Biosci Rep. 2017;37: pubmed publisher
  • western blot; mouse; loading ...; fig 2d
He Y, Northey J, Pelletier A, Kos Z, Meunier L, Haibe Kains B, et al. The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer. Oncogene. 2017;36:3490-3503 pubmed publisher
  • chromatin immunoprecipitation; mouse; loading ...; fig s2a
  • immunohistochemistry; mouse; 1:200; loading ...; fig 1a
Quintes S, Brinkmann B, Ebert M, Fröb F, Kungl T, Arlt F, et al. Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair. Nat Neurosci. 2016;19:1050-1059 pubmed publisher
  • western blot; human; 1:500; fig 5
Jiang S, He X, Xia Y, Hu W, Luo J, Zhang J, et al. MicroRNA-145-5p inhibits gastric cancer invasiveness through targeting N-cadherin and ZEB2 to suppress epithelial-mesenchymal transition. Onco Targets Ther. 2016;9:2305-15 pubmed publisher
  • western blot; human; fig 6k
Zhuang J, Lu Q, Shen B, Huang X, Shen L, Zheng X, et al. TGFβ1 secreted by cancer-associated fibroblasts induces epithelial-mesenchymal transition of bladder cancer cells through lncRNA-ZEB2NAT. Sci Rep. 2015;5:11924 pubmed publisher
  • western blot; human; fig 5
Zhao L, Liu S, Che X, Hou K, Ma Y, Li C, et al. Bufalin inhibits TGF-β-induced epithelial-to-mesenchymal transition and migration in human lung cancer A549 cells by downregulating TGF-β receptors. Int J Mol Med. 2015;36:645-52 pubmed publisher
  • western blot; human; loading ...; fig 2c
Qiao Y, Shiue C, Zhu J, Zhuang T, Jonsson P, Wright A, et al. AP-1-mediated chromatin looping regulates ZEB2 transcription: new insights into TNFα-induced epithelial-mesenchymal transition in triple-negative breast cancer. Oncotarget. 2015;6:7804-14 pubmed
Lin J, Zhang P, Liu W, Liu G, Zhang J, Yan M, et al. A positive feedback loop between ZEB2 and ACSL4 regulates lipid metabolism to promote breast cancer metastasis. elife. 2023;12: pubmed publisher
Chen Y, Fachko D, Ivanov N, Skalsky R. B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 Inhibition. mSphere. 2021;6: pubmed publisher
Jiang Y, Ji X, Liu K, Shi Y, Wang C, Li Y, et al. Exosomal miR-200c-3p negatively regulates the migraion and invasion of lipopolysaccharide (LPS)-stimulated colorectal cancer (CRC). BMC Mol Cell Biol. 2020;21:48 pubmed publisher
Kowolik C, Lin M, Xie J, Overman L, Horne D. Attenuation of hedgehog/GLI signaling by NT1721 extends survival in pancreatic cancer. J Exp Clin Cancer Res. 2019;38:431 pubmed publisher
Xie R, Tang J, Zhu X, Jiang H. Silencing of hsa_circ_0004771 inhibits proliferation and induces apoptosis in breast cancer through activation of miR-653 by targeting ZEB2 signaling pathway. Biosci Rep. 2019;39: pubmed publisher
Wang G, Jiao B, Liu Y, Li Y, Deng B. Reactivation of microRNA-506 inhibits gastric carcinoma cell metastasis through ZEB2. Aging (Albany NY). 2019;11:1821-1831 pubmed publisher
Yang J, Tian B, Sun H, Garofalo R, Brasier A. Epigenetic silencing of IRF1 dysregulates type III interferon responses to respiratory virus infection in epithelial to mesenchymal transition. Nat Microbiol. 2017;2:17086 pubmed publisher
Jimenez L, Lim J, Burd B, Harris T, Ow T, Kawachi N, et al. miR-375 Regulates Invasion-Related Proteins Vimentin and L-Plastin. Am J Pathol. 2017;187:1523-1536 pubmed publisher
Wright P, Li H, Huehn A, O Connor G, Cooley S, Miller J, et al. Characterization of a weakly expressed KIR2DL1 variant reveals a novel upstream promoter that controls KIR expression. Genes Immun. 2014;15:440-8 pubmed publisher
product information
Catalog Number :
sc-271984
Product Name :
ZEB2 (E-11) Antibody
Product Type :
Monoclonal
Host Species :
mouse
Clonality :
monoclonal
Clone Name :
E-11
Isotype :
IgG2a
Size :
200 µg/ml
List Price :
316 USD
Immunogen :
ZEB2
Specificity :
mouse, rat, human
Uses :
WB, IP, IF, ELISA
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
https://www.scbt.com
1.800.457.3801
headquarters: USA